Abstract:
OBJECTIVE:To study the effect of Lactobacillus helveticus fermented milk on sleep and health perception in elderly healthy subjects. SUBJECTS:The study included 29 healthy elderly subjects aged 60-81 years. METHODS:Prospective, randomized, double-blind and placebo-controlled, with a crossover design. The study included two intervention periods of 3 weeks each, separated by a 3-week washout period. Subjects took 100 g of fermented milk drink or a placebo drink (artificially acidified milk) daily in the first supplementary period and the other drink in the second supplementary period. For each period, we measured sleep quality by means of actigraphy and a sleep questionnaire, and assessed the quality of life (QOL) by SF-36 health survey. RESULTS:There was a significant improvement in sleep efficiency (P=0.03) and number of wakening episodes (P=0.007) in actigraph data after intake of fermented milk, whereas no significant changes were observed for the placebo. Fermented milk did not improve the SF-36 scores significantly from the baseline period. In the GH domain (general health perception) of the SF-36, however, there was marginal improvement as compared to the baseline period. Although the difference between fermented milk and placebo was not statistically significant for any of the sleep or QOL parameters, fermented milk produced slightly greater mean values for many parameters. CONCLUSION:This short-term (3-week) intervention study indicates that Lactobacillus helveticus fermented milk may have a more favorable effect on improving sleep in healthy elderly people as compared with placebo.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Yamamura S,Morishima H,Kumano-go T,Suganuma N,Matsumoto H,Adachi H,Sigedo Y,Mikami A,Kai T,Masuyama A,Takano T,Sugita Y,Takeda Mdoi
10.1038/sj.ejcn.1602898subject
Has Abstractpub_date
2009-01-01 00:00:00pages
100-5issue
1eissn
0954-3007issn
1476-5640pii
1602898journal_volume
63pub_type
杂志文章,随机对照试验abstract:BACKGROUND:Children in China with Autism Spectrum Disorders (ASD) are prone to vitamin A deficiency (VAD). The present study compared two vitamin A supplements (VAS) in two groups of children with ASD and VAD to explore a better VAS program for children with ASD. METHOD:A total of 138 3-8-year-old children with ASD (1...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-00827-9
更新日期:2020-12-16 00:00:00
abstract::The principal metabolic function of vitamin B6 is in amino acid metabolism, although the greater part of the body's vitamin B6 is in muscle, associated with glycogen phosphorylase, and the vitamin also has an important role in the actions of steroid hormones. It is usual to calculate vitamin B6 requirements relative t...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:1989-05-01 00:00:00
abstract::The present study tested the hypotheses that: (a) individual body composition estimates obtained with the Durnin-Womersley (D-W) equations have low validity in certain populations in developing countries; (b) there exists a poor relationship between the body mass index (BMI) and body composition estimates (fat mass (B...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
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abstract::Assessing diet through dietary patterns has become popular in diet-disease investigations due to the appealing simplicity of expressing several dietary exposures through one variable. Current evidence suggests that there may exist a priori and a posteriori dietary patterns that are consistently associated with reduced...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/s41430-018-0128-8
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abstract:BACKGROUND/OBJECTIVES:Long-term observational cohorts provide the opportunity to investigate the potential impact of dietary patterns on death. We aimed to investigate all-cause death according to the consumption of selected food groups, and then to identify those independently associated with reduced mortality. SUBJE...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.19
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:We set up a baseline data on urinary iodine excretion from a nationwide representative sample of rural schoolchildren before instituting iodine supplementation. DESIGN:Stratified multistage cluster sampling in three different strata: lowlands, foothills and mountainous areas. Early morning urine samples were...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600562
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abstract:OBJECTIVE:To evaluate glycaemic and insulinaemic index and in vitro digestibility of the five most common Cameroonian mixed meals consisting of rice+tomato soup (diet A), bean stew+plantains (B), foofoo corn+ndolé (C), yams+groundnut soup (D), and koki beans+cassava (E). SUBJECTS:Ten healthy non-obese volunteers, aged...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601592
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVE:To compare the relations of adiposity and body fat distribution to body mass index (BMI) in Australians of Aboriginal and European ancestry. DESIGN:Cross-sectional volunteer samples. SETTING:Australian Aboriginal communities in remote central and northern Australia, urban European Australians resident in Me...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601630
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of low and marginal iodine intake and urinary iodine excretion among adults in the Netherlands and to investigate determinants of urinary iodine excretion. DESIGN AND SUBJECTS:The study population consisted of 444 people aged 20-79 y, balanced for sex and 10 y age classes with an ove...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To investigate (i) associations of intimate partner violence (IPV) and chronic undernutrition among women of reproductive age and (ii) whether women who experience both poverty and IPV are unique in their nutritional disadvantages. SUBJECTS/METHODS:This study used the data from the 2007 Banglades...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2012.202
更新日期:2013-03-01 00:00:00
abstract::In this issue we would like to thank all those listed below for taking the time to review for the European Journal of Clinical Nutrition in 2019-your generosity is much appreciated and we hope your association with the journal continues in the future. ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-0589-4
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Protocols for enhanced recovery after surgery (ERAS) provide comprehensive and evidence-based guidelines to improve perioperative care. It remains elusive whether early enteral nutrition (EEN) will play an active role in the ERAS protocols. Laparoscopic common bile duct exploration (LCBDE) is a sa...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41430-019-0425-x
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abstract:BACKGROUND/OBJECTIVES:To examine students' beverage choice in school, with reference to its contribution to students' intake of non-milk extrinsic (NME) sugars. SUBJECTS/METHODS:Beverage and food selection data for students aged 11-18 years (n=2461) were collected from two large secondary schools in England, for a con...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.158
更新日期:2016-02-01 00:00:00
abstract::Consumers and patients are unsure of whom to trust for nutritional advice. Although medical doctors are seen as experts in nutrition and their advice is regularly followed, data are lacking on the amount of nutrition education in European medical school curricula. In line with US research, we distributed a survey on r...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.75
更新日期:2014-07-01 00:00:00
abstract::Adult (primary) lactose malabsorption is practically universal in Africans of Bantu and San ('Bushmen') stock. Recent environmental changes, especially in rural areas, have exacerbated rates of malnutrition in hospital patients belonging to these groups. In order to assess the advisability of using milk as a nutrition...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract:OBJECTIVE:To study the relation between indicators of infection and Schistosoma mansoni and S. haematobium infection, and serum concentrations of zinc, ferritin and retinol. DESIGN:Cross-sectional. SETTING AND SUBJECTS:313 rural Zimbabwean schoolchildren (144 boys and 169 girls, 11-17 years). VARIABLES:S. mansoni an...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::Energy density of foods, as opposed to their sugar or fat content, is said to be a key determinant of energy intakes. Recent laboratory studies have shown that, under ad lib conditions, subjects consume a constant weight or volume of food, so that their energy intakes depend on the energy density of the diet. Because ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1600879
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVE:To explore the association of eating styles with overweight and obesity in young adults, controlling for identical genetic background in monozygotic twins. DESIGN:Prospective twin cohort study. SETTING:Finland, 1991-2002. SUBJECTS:Two-hundred and thirty-three women and 2060 men from the FinnTwin16 study, a...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602601
更新日期:2007-07-01 00:00:00
abstract::The article deals with the generation of a prediction equation for basal metabolic rate (BMR) of well-nourished Indian males, from prospective measurements on 121 males, using a single validated technique. The equation related BMR to simple measures such as weight (WT) and age, and was given by: BMR (kJ/d) = 48.7 * WT...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:1993-06-01 00:00:00
abstract::The development of atherosclerotic vascular disease is influenced by multiple factors present since early age. Abnormal lipid metabolism, a major cause of atherosclerosis, results from genetic predisposition and is influenced by a variety of exogenous conditions. This article reviews the published studies of serum cho...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Coffee is one of the most popularly consumed beverages worldwide. Many epidemiological studies have investigated the association between coffee consumption and lung cancer risk, but the results are inconsistent. Hence, we conducted a systematic analysis of relevant population-based studies to exam...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,meta分析,评审
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更新日期:2016-02-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601064
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Diets rich in plant-based foods such as vegetables, fruits and soy foods have been suggested to have beneficial effects on health. However, phytochemicals contained in plant-based foods are generally bitter and acrid. We investigated whether intake of vegetables, fruits and soy foods is associated...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2011.127
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Urinary and plasma indices are utilized to assess whole-body water balance in healthy adults, whereas the urine-to-plasma osmolality ratio (Uosm:Posm) rarely is. To explore the efficacy of Uosm:Posm as a hydration biomarker, diet records of 120 college women were analyzed (beverage water+food wate...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.79
更新日期:2013-09-01 00:00:00
abstract::Nutrition affects the brain throughout life, with profound implications for cognitive decline and dementia. These effects are mediated by changes in expression of multiple genes, and responses to nutrition are in turn affected by individual genetic variability. An important layer of regulation is provided by the epige...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/ejcn.2014.173
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:To examine seasonality of 25-hydroxyvitamin D (25OH-D) levels in British preschool children and the effect of vitamin D supplementation on this. DESIGN:The National Diet and Nutrition Survey of children aged 1.5 4.5 y in Britain during 1992-3 measured dietary intakes and blood status indices, including thos...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600697
更新日期:1999-03-01 00:00:00
abstract::Infant feeding pattern was studied longitudinally from birth to 52 weeks among all infants born in the period September 1982-December 1984 in three villages in Madura, East Java (n = 687). Genuine demand breast-feeding was practised but it is the custom to force-feed infants from as early as the third day after birth ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Cross-sectionally, educational attainment is strongly associated with the prevalence of obesity, but this association is less clear for weight change during adult life. The objective of this study is to examine the association between educational attainment and weight change during adult life in t...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2012.55
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVES:Prevention of cardiovascular diseases by paleolithic or hunter-gatherer diets has been discussed during recent years. METHODS:Our aim was to assess the effect of a paleolithic diet in a pilot study on healthy volunteers during 3 weeks. The intention was to include 20 subjects, of whom 14 fulfilled the study...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602790
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To compare the effects of a rapeseed oil-based diet containing an increased proportion of easily oxidised polyunsaturated fatty acids such as alpha-linolenic acid with a diet rich in saturated fatty acids on the degree of lipid peroxidation in the human body. DESIGN:A randomised cross-over study. SUBJECTS A...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2001-11-01 00:00:00