Expression of the chemokine receptor CXCR3 and its ligand IP-10 during human cardiac allograft rejection.

abstract：BACKGROUND:In this study, we both investigated coronary flow velocity in hypertrophic obstructive cardiomyopathy (HOCM) and tested the hypothesis of differing coronary flow reserve (CFR) of coronary arteries perfusing left ventricular regions with nonuniform myocardial hypertrophy by measuring the relative CFR. METHOD...

journal_title：Circulation

authors： Kyriakidis MK,Dernellis JM,Androulakis AE,Kelepeshis GA,Barbetseas J,Anastasakis AN,Trikas AG,Tentolouris CA,Gialafos JE,Toutouzas PK

更新日期：1997-08-05 00:00:00

abstract：BACKGROUND:The myocardial protective role of heat shock protein (HSP) has been demonstrated, and there has been increasing interest in stress response in the heart. We examined the DNA-binding activity of heat shock transcription factor (HSF), by which the transcription of heat shock genes is mainly regulated, during h...

journal_title：Circulation

authors： Nishizawa J,Nakai A,Higashi T,Tanabe M,Nomoto S,Matsuda K,Ban T,Nagata K

更新日期：1996-11-01 00:00:00

abstract：:Neutrophil activation and infiltration into the ischemic myocardium after reperfusion may limit the amount of salvageable myocardium (reperfusion injury). The effects of intravenous perfluorochemicals (Fluosol-DA) on infarct size, ventricular contractility, and neutrophil function were assessed in an occlusion-reperfu...

journal_title：Circulation

authors： Bajaj AK,Cobb MA,Virmani R,Gay JC,Light RT,Forman MB

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Apoptosis is common in advanced human atheroma and contributes to plaque instability. Because annexin V has a high affinity for exposed phosphatidylserine on apoptotic cells, radiolabeled annexin V may be used for noninvasive detection of apoptosis in atherosclerotic lesions. METHODS AND RESULTS:Atheroscler...

journal_title：Circulation

authors： Kolodgie FD,Petrov A,Virmani R,Narula N,Verjans JW,Weber DK,Hartung D,Steinmetz N,Vanderheyden JL,Vannan MA,Gold HK,Reutelingsperger CP,Hofstra L,Narula J

更新日期：2003-12-23 00:00:00

abstract：BACKGROUND:Recognition of rates and causes of hard, patient-centered outcomes of death and cerebrovascular events (CVEs) after heart rhythm disorder management (HRDM) procedures is an essential step for the development of quality improvement programs in electrophysiology laboratories. Our primary aim was to assess and ...

journal_title：Circulation

authors： Lee JZ,Ling J,Diehl NN,Hodge DO,Padmanabhan D,Killu AM,Madhavan M,Noseworthy PA,Kapa S,McLeod CJ,Cha YM,Deshmukh AJ,Srivathsan K,Kusumoto FM,Shen WK,Friedman PA,Munger TM,Asirvatham SJ,Packer DL,Mulpuru SK

更新日期：2018-01-02 00:00:00

abstract：:Digoxin, in a common clinical dose and at a low serum level, brought out severe manifestations of sinus node dysfunction in a patient who had previously undergone successful mitral valve replacement. This report presents the results of extensive clinical and electrophysiologic studies of this patient before and after ...

journal_title：Circulation

authors： Margolis JR,Strauss HC,Miller HC,Gilbert M,Wallace AG

更新日期：1975-07-01 00:00:00

abstract：BACKGROUND:The role of angiotensin as a vasoconstrictor is well established. Lately, several other actions of this hormone on vascular smooth muscle (VSM) cells have been recognized including the induction of hypertrophy and/or DNA synthesis. Platelet-derived growth factor (PDGF), a mitogen recently shown to increase p...

journal_title：Circulation

authors： van Leeuwen RT,Kol A,Andreotti F,Kluft C,Maseri A,Sperti G

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Elevated levels of high-sensitivity C-reactive protein (hsCRP) are associated with higher risk of adverse outcomes in patients at risk for or with established coronary artery disease. Retrospective analyses suggest that this risk may be modified with statin therapy. However, a role for hsCRP in monitoring th...

journal_title：Circulation

authors： Morrow DA,de Lemos JA,Sabatine MS,Wiviott SD,Blazing MA,Shui A,Rifai N,Califf RM,Braunwald E

更新日期：2006-07-25 00:00:00

abstract：:Proton (hydrogen-1) magnetic resonance imaging techniques have potential for the detection and characterization of changes associated with myocardial ischemia. Since image contrast is dependent on T1 and T2 relaxation times, we examined these parameters in a canine preparation of occlusion of the left anterior descend...

journal_title：Circulation

authors： Johnston DL,Brady TJ,Ratner AV,Rosen BR,Newell JB,Pohost GM,Okada RD

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:We examined the association of 3 polymorphisms in the lectin-like oxidized LDL receptor-1 (LOX1 or OLR1) gene with coronary artery disease in the Women's Ischemia Syndrome Evaluation (WISE) study population. METHODS AND RESULTS:The WISE sample comprised 589 white and 122 black women who underwent angiograph...

journal_title：Circulation

authors： Chen Q,Reis SE,Kammerer C,Craig WY,LaPierre SE,Zimmer EL,McNamara DM,Pauly DF,Sharaf B,Holubkov R,Bairey Merz CN,Sopko G,Bontempo F,Kamboh MI

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Lung hypoplasia and persistent pulmonary hypertension of the newborn limit survival in congenital diaphragmatic hernia (CDH). Unlike other diseases resulting in persistent pulmonary hypertension of the newborn, infants with CDH are refractory to inhaled nitric oxide (NO). Nitric oxide mediates pulmonary vaso...

journal_title：Circulation

authors： Luong C,Rey-Perra J,Vadivel A,Gilmour G,Sauve Y,Koonen D,Walker D,Todd KG,Gressens P,Kassiri Z,Nadeem K,Morgan B,Eaton F,Dyck JR,Archer SL,Thébaud B

更新日期：2011-05-17 00:00:00

abstract：:We reviewed 35 patients undergoing resection of a chronic postinfarction left ventricular aneurysm. There was 5.7% operative mortality. Of the long-term survivors, 80% are functional class I or II. Ten patients had postoperative left ventriculograms studied by means of a computerized analysis of endocardial motion usi...

journal_title：Circulation

authors： Shaw RC,Connors JP,Hieb BR,Ludbrook PA,Krone R,Kleiger RE,Ferguson TB,Weldon CS

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:The lysyl oxidases are extracellular copper enzymes that initiate the crosslinking of collagens and elastin, 5 human isoenzymes having been characterized so far. The crosslinks formed provide the tensile strength and elastic properties for various extracellular matrices, including vascular walls. We studied ...

journal_title：Circulation

authors： Mäki JM,Räsänen J,Tikkanen H,Sormunen R,Mäkikallio K,Kivirikko KI,Soininen R

更新日期：2002-11-05 00:00:00

abstract：BACKGROUND:There is no published randomized study comparing amiodarone therapy and radiofrequency catheter ablation (RFA) after only 1 episode of symptomatic atrial flutter (AFL). The aim of the Loire-Ardèche-Drôme-Isère-Puy-de-Dôme (LADIP) Trial of Atrial Flutter was 2-fold: (1) to prospectively compare first-line RFA...

journal_title：Circulation

authors： Da Costa A,Thévenin J,Roche F,Romeyer-Bouchard C,Abdellaoui L,Messier M,Denis L,Faure E,Gonthier R,Kruszynski G,Pages JM,Bonijoly S,Lamaison D,Defaye P,Barthélemy JC,Gouttard T,Isaaz K,Loire-Ardèche-Drôme-Isère-Puy-de-D

更新日期：2006-10-17 00:00:00

abstract：BACKGROUND:We measured cardiovagal baroreflex gain and its vascular mechanical and neural components during dynamic baroreflex engagement in 10 young untrained men, 6 older untrained men, and 12 older, physically active men. METHODS AND RESULTS:Our newly developed assessment of beat-to-beat carotid diameters during ba...

journal_title：Circulation

authors： Hunt BE,Farquhar WB,Taylor JA

更新日期：2001-05-22 00:00:00

abstract：BACKGROUND:After a cavopulmonary anastomosis, the superior vena caval flow, by virtue of being the effective pulmonary blood flow, is the most important factor influencing the systemic arterial saturation. Determination of the amount of this blood flow will allow a better understanding of the physiology of the circulat...

journal_title：Circulation

authors： Salim MA,DiSessa TG,Arheart KL,Alpert BS

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Echocardiographically determined left ventricular hypertrophy (LVH) has a well-demonstrated association with cardiovascular morbidity and mortality. However, whether or not there is a sex differential in the impact of LVH on mortality has never been systematically explored. METHODS AND RESULTS:This study en...

journal_title：Circulation

authors： Liao Y,Cooper RS,Mensah GA,McGee DL

更新日期：1995-08-15 00:00:00

abstract：BACKGROUND:This study sought to evaluate the clinical impact of angiographic complete revascularization (CR) after drug-eluting stent implantation or coronary artery bypass graft surgery for multivessel coronary disease. METHODS AND RESULTS:A total of 1914 consecutive patients with multivessel coronary disease undergo...

journal_title：Circulation

authors： Kim YH,Park DW,Lee JY,Kim WJ,Yun SC,Ahn JM,Song HG,Oh JH,Park JS,Kang SJ,Lee SW,Lee CW,Park SW,Park SJ

更新日期：2011-05-31 00:00:00

abstract：:Twenty-one patients with documented coronary atherosclerotic heart disease were studied to determine the effect of high dose oral isosorbide dinitrate (ISDN) on heart rate, blood pressure, and exercise time until angina pectoris. Patients were tested in two phases, initially with 0.4 mg of sublingual nitroglycerin and...

journal_title：Circulation

authors： Danahy DT,Burwell DT,Aronow WS,Prakash R

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Molecular targeted chemotherapies have been shown to significantly improve the outcomes of patients who have cancer, but they often cause cardiovascular side effects that limit their use and impair patients' quality of life. Cardiac dysfunction induced by these therapies, especially trastuzumab, shows a dist...

journal_title：Circulation

authors： Kitani T,Ong SG,Lam CK,Rhee JW,Zhang JZ,Oikonomopoulos A,Ma N,Tian L,Lee J,Telli ML,Witteles RM,Sharma A,Sayed N,Wu JC

更新日期：2019-05-21 00:00:00

abstract：BACKGROUND:Functional mitral regurgitation (MR) is common in patients with heart failure and left ventricular (LV) dysfunction, and its severity may vary over time, depending primarily on the loading conditions. Because dynamic changes in the severity of functional MR may affect forward stroke volume, we hypothesized t...

journal_title：Circulation

authors： Lapu-Bula R,Robert A,Van Craeynest D,D'Hondt AM,Gerber BL,Pasquet A,Melin JA,De Kock M,Vanoverschelde JL

更新日期：2002-09-10 00:00:00

abstract：:Two-dimensional suprasternal notch echocardiography was performed in 1033 patients, ages 1 day to 18 years. For the long-axis suprasternal notch view, the transducer was positioned in the suprasternal notch and angled to obtain a plane passing between the right nipple and left scapular tip. In this view, the entire ao...

journal_title：Circulation

authors： Snider AR,Silverman NH

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Intentional weight loss is associated with lower risk of heart failure (HF) and atherosclerotic cardiovascular disease among patients with type 2 diabetes. However, the contribution of baseline measures and longitudinal changes in fat mass (FM), lean mass (LM), and waist circumference (WC) to the risk of HF ...

journal_title：Circulation

authors： Patel KV,Bahnson JL,Gaussoin SA,Johnson KC,Pi-Sunyer X,White U,Olson KL,Bertoni AG,Kitzman DW,Berry JD,Pandey A,Look AHEAD Research Group.

更新日期：2020-12-22 00:00:00

abstract：:Phasic blood flow recorded in five unobstructed dog aortocoronary bypass grafts to the left coronary artery was similar to that of normal coronary arteries, with a high diastolic-to-systolic flow ratio which averaged 2.7 +/- 0.4. With an average of 52 +/- 7% and 72 +/- 6% stenosis in the coronary artery distal to the ...

journal_title：Circulation

authors： Folts JD,Kahn DR,Bittar N,Rowe GG

更新日期：1975-08-01 00:00:00

abstract：:Verapamil, a calcium antagonist, has been used extensively for treatment of cardiac arrhythmias. Concern persists, however, that it may seriously depress myocardial function in cardiac patients. To investigate this possibility, 20 patients with coronary artery disease (CAD) but no heart failure were given intravenous ...

journal_title：Circulation

authors： Ferlinz J,Easthope JL,Aronow WS

更新日期：1979-02-01 00:00:00

abstract：:Organ donor scarcity has resulted in an increasing number of long-distance cardiac allograft procurements. The effect on short-term (90-day) survival and cardiac function was assessed in a consecutive series of 167 heart transplants performed between April 1981 and July 1988. During that time, total allograft ischemic...

journal_title：Circulation

authors： Pflugfelder PW,Thomson D,Singh NR,Menkis AH,McKenzie FN,Kostuk WJ

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:The use of balloon coarctation angioplasty instead of surgery as treatment for unoperated coarctation of the aorta is controversial. The efficacy and complications of the two procedures have not been studied before in a prospective fashion. METHODS AND RESULTS:Thirty-six patients were prospectively randomiz...

journal_title：Circulation

authors： Shaddy RE,Boucek MM,Sturtevant JE,Ruttenberg HD,Jaffe RB,Tani LY,Judd VE,Veasy LG,McGough EC,Orsmond GS

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:We measured the content and activities of components of the beta-adrenergic receptor-G protein-adenylate cyclase complex and adrenergic neurotransmitter levels in left and right ventricular myocardial preparations derived from 77 end-stage failing human hearts from patients with idiopathic dilated cardiomyop...

journal_title：Circulation

authors： Bristow MR,Anderson FL,Port JD,Skerl L,Hershberger RE,Larrabee P,O'Connell JB,Renlund DG,Volkman K,Murray J

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Chronic Chlamydia pneumoniae and Helicobacter pylori infections could be a risk factor for ischemic heart disease (IHD), possibly by increasing fibrinogen levels. The aim of our study was to evaluate changes in fibrinogen level in patients with IHD and H pylori and/or C pneumoniae positivity randomly assigne...

journal_title：Circulation

authors： Torgano G,Cosentini R,Mandelli C,Perondi R,Blasi F,Bertinieri G,Tien TV,Ceriani G,Tarsia P,Arosio C,Ranzi ML

更新日期：1999-03-30 00:00:00

abstract：BACKGROUND:Chronic heart failure is associated with endothelial dysfunction including impaired endothelium-mediated, flow-dependent dilation (FDD). Since endothelial function is thought to play an important role in coordinating tissue perfusion and modulating arterial compliance, interventions to improve endothelial dy...

journal_title：Circulation

authors： Hornig B,Maier V,Drexler H

更新日期：1996-01-15 00:00:00