Abstract:
BACKGROUND:After a cavopulmonary anastomosis, the superior vena caval flow, by virtue of being the effective pulmonary blood flow, is the most important factor influencing the systemic arterial saturation. Determination of the amount of this blood flow will allow a better understanding of the physiology of the circulation after this anastomosis. The purposes of this study were to determine the volumetric flow in the superior vena cava and to evaluate its contribution to the cardiac output as children grow. METHODS AND RESULTS:Using two-dimensional and Doppler echocardiography, we measured the diameter of and mean flow velocities in the superior venae cavae and the pulmonary arteries of 145 healthy children. We calculated the volumetric flow in each vessel and determined the ratio of superior vena caval flow to total cardiac output. Cardiac output and superior vena caval flow increased with increasing age and body surface area. The superior vena caval flow accounted for 49% of cardiac output in newborn infants. This contribution increased to a maximum of 55% at the age of 2.5 years. Afterward, there was a slow decline in the ratio of superior vena caval-pulmonary arterial flow; it reached the adult value of 35% by 6.6 years of age. CONCLUSIONS:There is a maturational change in the superior vena caval contribution to total cardiac output in children. This is most likely related to somatic growth and changes in body segment proportions. This flow maturation may explain the higher systemic saturation in infants compared with older children after cavopulmonary anastomosis.
journal_name
Circulationjournal_title
Circulationauthors
Salim MA,DiSessa TG,Arheart KL,Alpert BSdoi
10.1161/01.cir.92.7.1860subject
Has Abstractpub_date
1995-10-01 00:00:00pages
1860-5issue
7eissn
0009-7322issn
1524-4539journal_volume
92pub_type
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