Abstract:
:1. The effect of gender, smoking and pubertal development on platelet monoamine oxidase (MAO) activity was described in a randomly selected, large sample of 9- and 15-years old healthy children. 2. Platelet MAO activity was measured in 1129 children by a radioenzymatic method with beta-phenylethylamine as the substrate. Smoking habits were reported in an anonymous questionnaire. Pubertal status was assessed visually using Tanner's stages. 3. Boys, younger children and smokers had significantly lower platelet MAO activity than girls, older children and non-smokers, respectively. Girls in Tanner's stage V for breast and pubic hair development had significantly lower MAO than girls in stage IV. 4. Differences in gender, age, pubertal status and smoking habits must be taken into account if the relationship between platelet MAO activity, personality and psychiatric disorders is studied in children.
journal_name
Prog Neuropsychopharmacol Biol Psychiatryauthors
Harro M,Eensoo D,Kiive E,Merenäkk L,Alep J,Oreland L,Harro Jdoi
10.1016/s0278-5846(01)00212-3subject
Has Abstractpub_date
2001-11-01 00:00:00pages
1497-511issue
8eissn
0278-5846issn
1878-4216pii
S0278-5846(01)00212-3journal_volume
25pub_type
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