Kinetic and cardiovascular comparison of immediate-release isradipine and sustained-release isradipine among non-treatment-seeking, cocaine-dependent individuals.

abstract：:Synaptic dysfunction has recently gained attention for its involvement in mood disorders. Electroconvulsive therapy (ECT) possibly plays a role in synaptic repair. However, the underlying mechanisms remain uncertain. Thrombospondin-1 (TSP-1), a member of the TSP family, is reported to be secreted by astrocytes and to ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Okada-Tsuchioka M,Segawa M,Kajitani N,Hisaoka-Nakashima K,Shibasaki C,Morinobu S,Takebayashi M

更新日期：2014-01-03 00:00:00

abstract：:Spinophilin is a multifunctional scaffold protein that regulates the formation and function of dendritic spines and plays a role in neuronal migration. The distinct roles of spinophilin depend on its localization and the direct interaction with other proteins, which may target spinophilin to specific locations within ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Brocos-Mosquera I,Nuñez Del Moral A,Morentin B,Meana JJ,Callado LF,Erdozain AM

更新日期：2018-02-02 00:00:00

abstract：:1. Twenty-two patients hospitalized for treatment of depression were treated under conditions simulating those of home treatment. 2. Full doses of nortriptyline, from 100 to 150 mg/day, were started after baseline observations were made. 3. Two patients were dropped from the study, one for orthostatic hypotension, one...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Peabody C,Van Norman J,Hollister L,Warner D

更新日期：1991-01-01 00:00:00

abstract：:Characteristics of primary cultures of neurons or of astrocytes are discussed which suggest that such cultures are appropriate models for their in vivo counterparts. Advantages or disadvantages of these cultures for studies of receptor binding are: Neuronal and astrocytic binding can be studied separately. Binding can...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Hertz L,Bender AS,Richardson JS

更新日期：1983-01-01 00:00:00

abstract：:The authors investigated the impact of the CYP2D6 genotypes on the plasma concentration of paroxetine (PAX) in 55 Japanese psychiatric patients. They were administered 10 to 40 mg/day (24+/-10.0 mg/day) of PAX and maintained at the same daily dose for at least two weeks to obtain the steady-state concentrations. The p...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Ueda M,Hirokane G,Morita S,Okawa M,Watanabe T,Akiyama K,Shimoda K

更新日期：2006-05-01 00:00:00

abstract：:1. Alzheimer's Disease (AD) is accompanied by a disruption in iron metabolism. There is no universally accepted method for detecting brain iron. 2. The authors have developed a novel "ratio" method which uses the red nucleus as an internal reference. We postulated that this method would improve our sensitivity in dete...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Parsey RV,Krishnan KR

更新日期：1997-11-01 00:00:00

abstract：:1. Leukocyte enumeration through flow cytometry has revealed that severe depression may be accompanied by a systemic immune activation, indicative of an inflammatory response. The latter condition allegedly involves an important modification of acute phase plasma protein (APP) equilibrium. 2. In order to elucidate whe...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Maes M,Scharpe S,Bosmans E,Vandewoude M,Suy E,Uyttenbroeck W,Cooreman W,Vandervorst C,Raus J

更新日期：1992-07-01 00:00:00

abstract：:A major component of opiate reward is derived from a drug action in the ventral tegmental area: (a) rats quickly learn to self-administer morphine directly into the ventral tegmentum, (b) intracranial self-administration into other brain sites is not quickly learned, and (c) narcotic antagonist microinjections into th...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Bozarth MA,Wise RA

更新日期：1983-01-01 00:00:00

abstract：:1. To test the hypothesis that lithium-induced body weight gain is related to an unbalance in the reproductive hormones, lithium carbonate (900 mg/day) or placebo was administered to healthy men for 1 month. 2. Body weight, skin folds and the serum levels of thyrotropic hormone, tetraiodothyroxine, prolactin, follicle...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Baptista T,Alastre T,Contreras Q,Martinez JL,Araujo de Baptista E,Burguera JL,de Burguera M,Hernández L

更新日期：1997-08-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Nutrition, as part of lifestyle and modifiable environmental factors, constitutes an interesting approach for the prevention of geriatric syndromes. The objective of this review was to examine the most recent evidence on the association between nutrition, from dietary patterns to specific nutrient...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Feart C

更新日期：2019-12-20 00:00:00

abstract：:The effect of electrical vagus nerve stimulation (VNS) on sleep and behavior was analyzed in freely moving cats. Eight cats were prepared for 23-h sleep recordings. The left vagus nerve of four of them was stimulated during 1 min, five times at 1-h intervals, for 5 days. The VNS induces: ipsilateral myosis, blinking, ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Valdés-Cruz A,Magdaleno-Madrigal VM,Martínez-Vargas D,Fernández-Mas R,Almazán-Alvarado S,Martínez A,Fernández-Guardiola A

更新日期：2002-01-01 00:00:00

abstract：:1. Genetic databases are an expanding and readily accessible repository of information on the mapping and sequencing of the human genome, and that of other model organisms. The integration and application of this information to neuropsychiatric disease is illustrated using neuroendocrine and neuropharmacologic data, c...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Jaworski M,Edwards E

更新日期：1991-01-01 00:00:00

abstract：:The aversive experience we call "pain" results from the coordinated activation of multiple brain areas, commonly described as a "pain matrix". This is not a fixed arrangement of structures but rather a fluid system composed of several interacting networks: A 'nociceptive matrix' includes regions receiving input from a...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Garcia-Larrea L,Bastuji H

更新日期：2018-12-20 00:00:00

abstract：:Physical exercise protocols have varied widely across studies raising the question of whether there is an optimal intensity, duration and frequency that would produce maximal benefits in attenuating symptoms related to anxiety disorders. Although physical exercise causes modifications in neurotransmission systems, the...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Costa MS,Ardais AP,Fioreze GT,Mioranzza S,Botton PH,Portela LV,Souza DO,Porciúncula LO

更新日期：2012-01-10 00:00:00

abstract：:Delayed carbon monoxide (CO) encephalopathy is a serious complication of acute CO poisoning. We present a case of successful treatment of ziprasidone, a newer atypical antipsychotic, in delayed CO encephalopathy. A 52-year-old depressed woman suffered acute CO intoxication after an attempt of suicide by burning charco...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Hu MC,Shiah IS,Yeh CB,Chen HK,Chen CK

更新日期：2006-06-01 00:00:00

abstract：:Ibogaine (IBO) is an alkaloid with putative antiaddictive properties, alleviating opiates dependence and withdrawal. The glutamate N-methyl-D-aspartate (NMDA) receptors have been implicated in the physiological basis of drug addiction; accordingly, IBO acts as a noncompetitive NMDA antagonist. The purpose of this stud...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Leal MB,Michelin K,Souza DO,Elisabetsky E

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Open and randomized, double blind, placebo-controlled clinical trials have demonstrated clinical efficacy of infrared whole-body hyperthermia in treatment of major depressive disorder (MDD). Demonstration of antidepressant-like behavioral effects of whole-body hyperthermia in preclinical rodent models would ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Hale MW,Lukkes JL,Dady KF,Kelly KJ,Paul ED,Smith DG,Raison CL,Lowry CA

更新日期：2017-10-03 00:00:00

abstract：:Apoptosis is a form of programmed cell death that results in the orderly and efficient removal of damaged or unnecessary cells, such as those resulting from DNA damage or during development. There are many factors that contribute to this process, each demonstrating specificity of function, regulation, and pathway invo...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Ashe PC,Berry MD

更新日期：2003-04-01 00:00:00

abstract：:1. Adrafmil is a novel vigilance promoting agent developed in France by Louis Lafon Laboratories. 2. Adrafinil causes increased locomotion without producing stereotypical activity in canines tested in an open field. 3. The effectiveness of a single treatment is long-lasting, and the effectiveness persists over repeate...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Siwak CT,Callahan H,Milgram NW

更新日期：2000-07-01 00:00:00

abstract：:A number of neuroprotective effects of curcumin have been demonstrated in recent years. However, whether curcumin exerts any beneficial effects on age-related impaired cognition and memory has not been well characterized; nor was there any detailed data on the molecular pathways activated by curcumin. The present stud...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Yu SY,Zhang M,Luo J,Zhang L,Shao Y,Li G

更新日期：2013-08-01 00:00:00

abstract：:1. 15 schizophrenic patients diagnosed according to criteria of I.C.D.-9 were treated with d1-propranolol in a 4 week open study. 2. A fixed dose schedule was followed and a maximum dose of 1920 mg/day was reached by day 17. 3. Results revealed a significant reduction in core schizophrenic symptoms of CPRS & BPRS star...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Sethi BB,Dubé S

更新日期：1983-01-01 00:00:00

abstract：:Previous studies have reported abnormalities in static brain activity and connectivity in patients with generalized anxiety disorder (GAD). However, the dynamic patterns of brain connectivity in patients with GAD have not been fully explored. In this study, we aimed to investigate the dynamic local brain functional co...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Cui Q,Chen Y,Tang Q,Han S,Hu S,Pang Y,Lu F,Nan X,Sheng W,Shen Q,Wang Y,He Z,Chen H

更新日期：2020-04-20 00:00:00

abstract：:People with Huntington's disease (HD) exhibit altered processing of emotional information, especially disgust and other negative emotions. These impairments are likely due to the effects of the disease on underlying brain networks. We examined whether oxytocin, when given intranasally, would normalise aberrant brain r...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Labuschagne I,Poudel G,Kordsachia C,Wu Q,Thomson H,Georgiou-Karistianis N,Stout JC

更新日期：2018-02-02 00:00:00

abstract：:1. Type I risk factor for tardive dyskinesia is defined as a risk leading primarily to a reversible form, while Type II factors to irreversible forms. 2. Central anticholinergic drugs appear as the prototype of Type I drug factor which increased the clinical manifestations of the disorder, but not its overall incidenc...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Chouinard G,Steinberg S

更新日期：1982-01-01 00:00:00

abstract：:The term "drug of abuse" is highly contextual. What constitutes a drug of abuse for one population of patients does not for another. It is therefore important to examine the needs of the patient population to properly assess the status of drugs of abuse. The focus of this article is on the bidirectional relationship b...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Mursaleen LR,Stamford JA

更新日期：2016-01-04 00:00:00

abstract：:Deficits in serotonergic (5-HT-ergic) neurotransmission and stressful life events have been implicated in affective disorders, and chronic variable stress (CVS) can elicit behavioral changes reminiscent of increased emotionality, anxiety and atypical depression after partial 5-HT depletion. This study examined the eff...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Tõnissaar M,Mällo T,Eller M,Häidkind R,Kõiv K,Harro J

更新日期：2008-01-01 00:00:00

abstract：:1. Agonists may act at any one of three sites on the N-methyl-D-aspartate (NMDA) receptor-effector complex to promote opening of the associated ion channel. The three sites are activated by i) NMDA, L-glutamate, aspartate, and other dicarboxylic amino acids; ii) glycine, D-serine, D-cycloserine, and others; iii) the p...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Lehmann J,Colpaert F,Canton H

更新日期：1991-01-01 00:00:00

abstract：:There is strong evidence that oxygen free radicals may play an important role in the pathophysiology of schizophrenia. Impaired antioxidant defense and increased lipid peroxidation have been previously reported in drug-naïve, first episode and chronically medicated schizophrenic patients using typical neuroleptics. We...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Gama CS,Salvador M,Andreazza AC,Kapczinski F,Silva Belmonte-de-Abreu P

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:An abnormality in regional cerebral blood flow (rCBF) in anorexia nervosa (AN) patients has been reported. There are very few studies that have investigated the rCBF changes in the recovery process of AN. METHODS:For eight female AN patients, we performed (123)I-IMP single photon emission computed tomograph...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Matsumoto R,Kitabayashi Y,Narumoto J,Wada Y,Okamoto A,Ushijima Y,Yokoyama C,Yamashita T,Takahashi H,Yasuno F,Suhara T,Fukui K

更新日期：2006-09-30 00:00:00

abstract：:Autism (MIM 209850) is a neurodevelopmental disorder characterized by difficulties with verbal and non-verbal communication, impairments in reciprocal social interactions, and displays of stereotypic behaviors, interests and activities. Twin and family studies have indicated a robust role of genetic factors in the dev...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Marui T,Koishi S,Funatogawa I,Yamamoto K,Matsumoto H,Hashimoto O,Ishijima M,Nanba E,Nishida H,Sugiyama T,Kasai K,Watanabe K,Kano Y,Kato N,Sasaki T

更新日期：2007-05-09 00:00:00