Abstract：
:The effect of electrical vagus nerve stimulation (VNS) on sleep and behavior was analyzed in freely moving cats. Eight cats were prepared for 23-h sleep recordings. The left vagus nerve of four of them was stimulated during 1 min, five times at 1-h intervals, for 5 days. The VNS induces: ipsilateral myosis, blinking, licking, abdominal contractions, upward gaze, swallowing, and eventually yawning and compulsive eating, as well as an increase of ponto-geniculate-occipital (PGO) wave density and of the number of stages and total amount of rapid eye movement (REM) sleep. Besides, there was a sudden transition from waking stage to REM sleep. The present results suggest that VNS modifies sleep in the cat. This effect could be explained by an activation of the areas involved in the physiological mechanisms of sleep.
journal_name
Prog Neuropsychopharmacol Biol Psychiatryauthors
Valdés-Cruz A,Magdaleno-Madrigal VM,Martínez-Vargas D,Fernández-Mas R,Almazán-Alvarado S,Martínez A,Fernández-Guardiola Adoi
10.1016/s0278-5846(01)00228-7subject
Has Abstractpub_date
2002-01-01 00:00:00pages
113-8issue
1eissn
0278-5846issn
1878-4216pii
S0278-5846(01)00228-7journal_volume
26pub_type
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