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Biological markers in alcoholism.

Abstract：

:The search for biological markers of a predisposition towards alcoholism is the result of data indicating that this disorder is genetically influenced. The present paper reviews some methodological considerations important for trait marker research in alcoholism. To date, the most promising results have come from studies comparing populations at elevated risk (i.e., sons of alcoholics) to controls. Such investigations point towards a decreased intensity of reaction to ethanol in sons of alcoholics, a decreased amplitude of the P300 wave of event-related potentials, and the possibility of a unique pattern of waves on the background cortical EEGs. The potential implication of these findings is discussed.

journal_name

Prog Neuropsychopharmacol Biol Psychiatry

journal_title

Progress in neuro-psychopharmacology & biological psychiatry

authors

Schuckit MA

doi

10.1016/0278-5846(86)90073-4

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

191-9

issue

2

eissn

0278-5846

issn

1878-4216

journal_volume

10

pub_type

杂志文章

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