Abstract:
:Chronic abusers of alcohol and other drugs often exhibit persistent deficits on neuropsychological tests. These deficits are usually attributed to drug-induced brain dysfunction or to familial factors that depress performance independent of drug abuse. The aim of this study was to determine the plausibility of a third explanation: namely that some neuropsychological deficits of drug abusers arise because they acquire different forms of knowledge from non-drug abusers. This hypothesis predicts that drug abusers should excel on tests of knowledge that is related to their lifestyle. Sixty-three clients from a local methadone clinic and a comparison group of 24 non-abusing subjects who were knowledgeable about drugs listened to a song about cocaine addiction. They were asked to identify the title, artist, year the song was first popular and the meaning of the song. There were no significant differences between the groups in identifying the song title, artist or year, but the drug-abusers were significantly more likely to state that the song was about cocaine or drug addiction. In interpreting deficits by drug abusers on neuropsychological tests, differences in knowledge acquired should be considered.
journal_name
Prog Neuropsychopharmacol Biol Psychiatryauthors
Beatty WW,Borrell GKdoi
10.1016/s0278-5846(99)00086-xsubject
Has Abstractpub_date
2000-01-01 00:00:00pages
17-22issue
1eissn
0278-5846issn
1878-4216pii
S027858469900086Xjournal_volume
24pub_type
临床试验,杂志文章abstract::The serotonin 1B receptor (5-HT1B) is important to both the pathogenesis of major depressive disorder and the antidepressant effects of selective serotonin reuptake inhibitors. Although fluoxetine has been shown to be effective and safe in children and adolescents, not all patients experience a proper clinical respons...
journal_title:Progress in neuro-psychopharmacology & biological psychiatry
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章,评审
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 临床试验,杂志文章,多中心研究
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更新日期:2006-09-30 00:00:00
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
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更新日期:2006-08-30 00:00:00
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
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更新日期:1998-01-01 00:00:00
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
doi:10.1016/j.pnpbp.2013.05.001
更新日期:2013-08-01 00:00:00
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
doi:10.1016/j.pnpbp.2006.04.013
更新日期:2006-08-30 00:00:00
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
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更新日期:2003-09-01 00:00:00
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
doi:10.1016/j.pnpbp.2011.03.023
更新日期:2011-07-01 00:00:00
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章,随机对照试验
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更新日期:2018-06-08 00:00:00
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
doi:10.1016/j.pnpbp.2004.06.009
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 临床试验,杂志文章
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更新日期:2008-12-12 00:00:00
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
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更新日期:2009-06-15 00:00:00
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章,随机对照试验
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
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更新日期:2001-10-01 00:00:00
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
doi:10.1016/j.pnpbp.2017.07.009
更新日期:2017-10-03 00:00:00
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journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.pnpbp.2003.11.018
更新日期:2004-05-01 00:00:00
abstract::1. Dopamine agonists and dopamine releasers act at the level of the striatum to activate a mossy fiber pathway which in turn increases cerebellar cGMP in the rodent. 2. CCK acts to both decrease basal cerebellar cGMP levels as well as to antagonize increases in cerebellar cGMP elicited by dopaminergic agonists and rel...
journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
doi:10.1016/0278-5846(89)90139-5
更新日期:1989-01-01 00:00:00
abstract::There is some evidence in animals that dopamine (DA) affects melatonin secretion. The effect of apomorphine (Apo), a selective DA receptor agonist, and placebo on day-time melatonin secretion was studied in six normal men. Apo HCl in a dose (0.5 mg sc) which increased growth hormone secretion in all subjects had no ef...
journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 临床试验,杂志文章
doi:10.1016/0278-5846(87)90065-0
更新日期:1987-01-01 00:00:00