Metabolic treatment of hyperuricosuric autism.

Abstract:

:A single male subject with hyperuricosuric autism was treated for a period of 2 years with an oral dose of uridine, which increased from 50 to 500 mg/kg/day. This patient experienced dramatic social, cognitive, language, and motor improvements. These improvement decreased within 72 h of the discontinuation of uridine, but reappeared when uridine supplementation was resumed. Thus, it appears that patients with hyperuricosuric autism benefit from metabolic therapy with oral uridine therapy in a manner similar to that seen in other disorders of purine metabolism in which there is autistic symptomatology.

authors

Page T,Moseley C

doi

10.1016/s0278-5846(01)00249-4

subject

Has Abstract

pub_date

2002-02-01 00:00:00

pages

397-400

issue

2

eissn

0278-5846

issn

1878-4216

pii

S0278-5846(01)00249-4

journal_volume

26

pub_type

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