Effect of apomorphine on melatonin secretion in normal subjects.

Abstract:

:There is some evidence in animals that dopamine (DA) affects melatonin secretion. The effect of apomorphine (Apo), a selective DA receptor agonist, and placebo on day-time melatonin secretion was studied in six normal men. Apo HCl in a dose (0.5 mg sc) which increased growth hormone secretion in all subjects had no effect on day-time melatonin concentrations in plasma. In keeping with other clinical studies these data suggest that melatonin secretion is not regulated by a DA mechanism in man.

authors

Lal S,Isaac I,Pilapil C,Nair NP,Hariharasubramanian N,Guyda H,Quirion R

doi

10.1016/0278-5846(87)90065-0

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

229-33

issue

2-3

eissn

0278-5846

issn

1878-4216

journal_volume

11

pub_type

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