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Type I tardive dyskinesia induced by anticholinergic drugs, dopamine agonists and neuroleptics.

Abstract：

:1. Type I risk factor for tardive dyskinesia is defined as a risk leading primarily to a reversible form, while Type II factors to irreversible forms. 2. Central anticholinergic drugs appear as the prototype of Type I drug factor which increased the clinical manifestations of the disorder, but not its overall incidence. 3. Clinical investigations of dopamine agonists suggest an important role for them in clinical management and understanding of neuroleptic-induced supersensitivity disorder. 4. We would like to propose a new classification of neuroleptics. Type I neuroleptics (estrogens, diphenylbutylpiperidines) are associated with milder and reversible dyskinesia, while Type II (Classical neuroleptics) with severe and irreversible forms.

journal_name

Prog Neuropsychopharmacol Biol Psychiatry

journal_title

Progress in neuro-psychopharmacology & biological psychiatry

authors

Chouinard G,Steinberg S

doi

10.1016/s0278-5846(82)80151-6

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

571-8

issue

4-6

eissn

0278-5846

issn

1878-4216

pii

S0278-5846(82)80151-6

journal_volume

6

pub_type

杂志文章

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