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There is no influence of a temperature rise on in vivo adsorption of UV filters into the stratum corneum.

Abstract：

:Temperature influences the stratum corneum adsorption of several topically applied compounds. This study was designed to evaluate the influence of the temperature on the stratum corneum adsorption of 3 UV filters. The UV filters were solubilized in two vehicles, an emulsion gel and petroleum jelly and applied at respectively, 31 and 40 degrees C during 30 min. In vivo stratum corneum UV filter content was measured using the tape stripping method. Similar amounts of UV filter were detected in the stratum corneum when comparing applications at the different temperatures. Application of the UV filters in the emulsion gel resulted in higher stratum corneum UV filter concentrations compared with application in the petroleum jelly. The application temperature did not influence the stratum corneum adsorption of the tested UV filters while the nature of the vehicle significantly influenced the amount of UV filters recovered from the stratum corneum.

journal_name

J Dermatol Sci

journal_title

Journal of dermatological science

authors

Clarys P,Gabard B,Lambrecht R,Barel A,Bieli E,Lüdi S

doi

10.1016/s0923-1811(01)00100-1

subject

Has Abstract

pub_date

2001-10-01 00:00:00

pages

77-81

issue

2

eissn

0923-1811

issn

1873-569X

pii

S0923181101001001

journal_volume

27

pub_type

杂志文章

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