The effect of perioperative aspirin therapy in peripheral vascular surgery: a decision analysis.

Abstract:

:Patients who undergo infrainguinal revascularization surgery are at increased risk for perioperative thrombotic complications. Aspirin decreases thrombotic events in the nonoperative setting; however, aspirin is often discontinued to avoid perioperative hemorrhagic complications. We used a decision analysis to determine whether aspirin should be discontinued before infrainguinal revascularization surgery. Two strategies were compared: aspirin cessation 2 wk before surgery and aspirin continuation throughout the perioperative period. Clinical events examined included myocardial infarction, thrombotic cerebrovascular accident, hemorrhagic cerebrovascular accident, gastrointestinal hemorrhage, and incisional hemorrhagic complications. Event rates and effect of aspirin were obtained by using MEDLINE. The outcomes were perioperative mortality, life expectancy, and quality-adjusted life expectancy. According to the model, continued aspirin use decreased perioperative mortality rates from 2.78% to 2.05%. Continued aspirin use increased life expectancy from 14.83 to 14.89 yr and increased quality-adjusted life expectancy from 14.72 to 14.79 yr. Aspirin increased the number of hemorrhagic complications by 2.46%, primarily because of an increased incidence of non-life-threatening complications.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Neilipovitz DT,Bryson GL,Nichol G

doi

10.1097/00000539-200109000-00009

subject

Has Abstract

pub_date

2001-09-01 00:00:00

pages

573-80

issue

3

eissn

0003-2999

issn

1526-7598

journal_volume

93

pub_type

临床试验,杂志文章,meta分析
  • Possible air embolism during eye surgery.

    abstract::We report a case of possible air embolism during a three-port pars plana vitrectomy and air-fluid exchange of the vitreous cavity of the eye. After the start of intraocular air flushing, sudden tachycardia, a decrease in oxygen saturation and end-tidal carbon dioxide tension, and a distinct "mill-wheel" murmur were ob...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ANE.0000154304.63828.C0

    authors: Ledowski T,Kiese F,Jeglin S,Scholz J

    更新日期:2005-06-01 00:00:00

  • Intracranial pressure effects of dexmedetomidine in rabbits.

    abstract::The alpha 2-adrenergic receptor agonist dexmedetomidine produces an anesthetic state in a variety of species. Although its effects on cerebral blood flow and the electroencephalogram have been investigated, the effect of this drug on intracranial pressure (ICP) has not been reported previously. Dexmedetomidine therefo...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/00000539-199208000-00014

    authors: Zornow MH,Scheller MS,Sheehan PB,Strnat MA,Matsumoto M

    更新日期:1992-08-01 00:00:00

  • The current status of continuous noninvasive measurement of total, carboxy, and methemoglobin concentration.

    abstract::Intraoperative early detection of anemia, identifying toxic levels of carboxyhemoglobin after carbon monoxide exposure and titrating drug dosage to prevent toxic levels of methemoglobin are important goals. The pulse oximeter works by illuminating light into the tissue and sensing the amount of light absorbed. The sam...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,评审

    doi:10.1213/ANE.0b013e318233041a

    authors: Shamir MY,Avramovich A,Smaka T

    更新日期:2012-05-01 00:00:00

  • The effects of systemic lidocaine on airway tone and pulmonary function in asthmatic subjects.

    abstract:BACKGROUND:To prevent reflex-induced bronchoconstriction in patients with asthma, local anesthetics are commonly administered by aerosol or IV as adjunct medication. Lidocaine attenuates responsiveness to a neurally active stimulus that increases tone, but there is scant information about the effect of lidocaine on bas...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000260638.57139.87

    authors: Chang HY,Togias A,Brown RH

    更新日期:2007-05-01 00:00:00

  • Myocardial Injury After Noncardiac Surgery: Preoperative, Intraoperative, and Postoperative Aspects, Implications, and Directions.

    abstract::Myocardial injury after noncardiac surgery (MINS) differs from myocardial infarction in being defined by troponin elevation apparently from cardiac ischemia with or without signs and symptoms. Such myocardial injury is common, silent, and strongly associated with mortality. MINS is usually asymptomatic and only detect...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,评审

    doi:10.1213/ANE.0000000000004567

    authors: Ruetzler K,Khanna AK,Sessler DI

    更新日期:2020-07-01 00:00:00

  • The effect of intravenous lidocaine on brain activation during non-noxious and acute noxious stimulation of the forepaw: a functional magnetic resonance imaging study in the rat.

    abstract:BACKGROUND:Lidocaine can alleviate acute as well as chronic neuropathic pain at very low plasma concentrations in humans and laboratory animals. The mechanism(s) underlying lidocaine's analgesic effect when administered systemically is poorly understood but clearly not related to interruption of peripheral nerve conduc...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ane.0b013e31818e0d34

    authors: Luo Z,Yu M,Smith SD,Kritzer M,Du C,Ma Y,Volkow ND,Glass PS,Benveniste H

    更新日期:2009-01-01 00:00:00

  • Recovery of the swallowing reflex after propofol anesthesia.

    abstract::The swallowing reflex is depressed by anesthetics. During recovery from anesthesia the rapid return of laryngeal and upper airway reflexes is important to protect the lower airway from aspiration. This study measures the recovery of the swallowing reflex after propofol anesthesia. Fifteen patients undergoing a colonos...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/00000539-199411000-00007

    authors: Rimaniol JM,D'Honneur G,Duvaldestin P

    更新日期:1994-11-01 00:00:00

  • The mechanism of helium-induced preconditioning: a direct role for nitric oxide in rabbits.

    abstract:BACKGROUND:Helium produces preconditioning against myocardial infarction by activating prosurvival signaling, but whether nitric oxide (NO) generated by endothelial NO synthase plays a role in this phenomenon is unknown. We tested the hypothesis that NO mediates helium-induced cardioprotection in vivo. METHODS:Rabbits...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ane.0b013e3181815995

    authors: Pagel PS,Krolikowski JG,Pratt PF Jr,Shim YH,Amour J,Warltier DC,Weihrauch D

    更新日期:2008-09-01 00:00:00

  • The impact of postoperative discontinuation or continuation of chronic statin therapy on cardiac outcome after major vascular surgery.

    abstract:BACKGROUND:Statins reduce cardiac morbidity in nonsurgical populations, and may benefit surgical patients. We sought to examine cardiac outcome in patients who continued, compared with those who discontinued, statin therapy after major vascular surgery. METHODS:Prospectively collected data were examined for an associa...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000263029.72643.10

    authors: Le Manach Y,Godet G,Coriat P,Martinon C,Bertrand M,Fléron MH,Riou B

    更新日期:2007-06-01 00:00:00

  • The incidence and prediction of automatically detected intraoperative cardiovascular events in noncardiac surgery.

    abstract:UNLABELLED:The objective of this study was to evaluate prognostic models for quality assurance purposes in predicting automatically detected intraoperative cardiovascular events (CVE) in 58458 patients undergoing noncardiac surgery. To this end, we assessed the performance of two established models for risk assessment ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000103262.26387.9c

    authors: Röhrig R,Junger A,Hartmann B,Klasen J,Quinzio L,Jost A,Benson M,Hempelmann G

    更新日期:2004-03-01 00:00:00

  • Release of beta-endorphin immunoreactive material under perioperative conditions into blood or cerebrospinal fluid: significance for postoperative pain?

    abstract::The function of beta-endorphin immunoreactive material (IRM) released under perioperative conditions remains to be clarified. In 17 patients undergoing orthopedic surgery, we determined beta-endorphin IRM in venous blood plasma and in cerebrospinal fluid (CSF) before surgery (t(A)); after termination of surgery and ge...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000539-200302000-00034

    authors: Matejec R,Ruwoldt R,Bödeker RH,Hempelmann G,Teschemacher H

    更新日期:2003-02-01 00:00:00

  • Sevoflurane inhibited beta-adrenoceptor-G protein bindings in myocardial membrane in rats.

    abstract::The effects of sevoflurane on the beta-adrenoceptor (beta AR) system, consisting of the receptor, stimulatory guanosine triphosphate (GTP) binding protein (Gs), and adenylate cyclase (AC), were studied in rat myocardial membrane. Cyclic adenosine monophosphate (cAMP) production rate was measured as cAMP generation sti...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/00000539-199409000-00011

    authors: Sanuki M,Yuge O,Kawamoto M,Fujii K,Azuma T

    更新日期:1994-09-01 00:00:00

  • Sufentanil pharmacokinetics in pediatric cardiovascular patients.

    abstract::The pharmacokinetics of sufentanil were studied in 28 pediatric patients undergoing cardiovascular procedures. Patients were divided into four groups on the basis of age: neonates (0-1 month, n = 9), infants (1-24 months, n = 7), children (2-12 yr, n = 7), and adolescents (12-18 yr, n = 5). Sufentanil 10-15 micrograms...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Greeley WJ,de Bruijn NP,Davis DP

    更新日期:1987-11-01 00:00:00

  • Sacroiliac joint radiofrequency ablation with a multilesion probe: a case series of 60 patients.

    abstract::This retrospective case series of patients with refractory sacroiliac joint (SIJ) pain presents our first 77 SIJ radiofrequency ablation (RFA) procedures performed with a multilesion probe. Of these, 16 (20.8%) provided no relief; 55 (71.4%) provided >50% pain relief at 6 weeks; 42 (54.5%, 95% confidence interval, 42....

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,多中心研究

    doi:10.1213/ANE.0000000000000282

    authors: Schmidt PC,Pino CA,Vorenkamp KE

    更新日期:2014-08-01 00:00:00

  • The inhibition of epidural morphine-induced pruritus by epidural droperidol.

    abstract:UNLABELLED:IV droperidol inhibits epidural morphine-induced pruritus, but this effect disappears when the dose is increased from 2.5 to 5.0 mg. This study was performed to determine whether epidural droperidol would have a similar effect. In this double-blinded study, we enrolled 140 patients undergoing Cesarean delive...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-200003000-00025

    authors: Horta ML,Ramos L,Gonçalves ZR

    更新日期:2000-03-01 00:00:00

  • Comparison of intramuscular dexmedetomidine and midazolam premedication for elective abdominal hysterectomy.

    abstract::The purpose of this study was to compare the perioperative effects of the intramuscular (i.m.) alpha 2 agonist, dexmedetomidine (DEX), and midazolam (MID) premedication. The study comprised 192 women (64 per group) scheduled for abdominal hysterectomy. The doses of the study drugs were chosen to obtain equal sedative ...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1213/00000539-199410000-00006

    authors: Erkola O,Korttila K,Aho M,Haasio J,Aantaa R,Kallio A

    更新日期:1994-10-01 00:00:00

  • Lack of CNS depression from large doses of trimethaphan in sheep.

    abstract::It is not uncommon to observe prolonged CNS depression for several hours following controlled hypotension and halothane anesthesia for neurosurgery. The present study evaluates possible contribution of large doses of trimethaphan to CNS depression. Four adult sheep were placed on transapical left ventricular bypass (T...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/00000539-197701000-00005

    authors: Wong KC,Peters JL,Roberts TS,McRea JC,Fukumasu H

    更新日期:1977-01-01 00:00:00

  • Cyclosporine can increase isoflurane MAC.

    abstract:UNLABELLED:Previous reports indicate that cyclosporine increases sleeping time from barbiturate administration, and analgesia from fentanyl administration, suggesting a possible contribution of cyclosporine to anesthesia. Accordingly, we determined whether cyclosporine pretreatment decreases isoflurane MAC (the minimum...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200210000-00025

    authors: Niemann CU,Stabernack C,Serkova N,Jacobsen W,Christians U,Eger EI 2nd

    更新日期:2002-10-01 00:00:00

  • Solubility of I-653, sevoflurane, isoflurane, and halothane in plastics and rubber composing a conventional anesthetic circuit.

    abstract::This study defines some characteristics of a standard anesthetic circuit that may impede anesthetic induction and recovery with I-653, sevoflurane, isoflurane, and halothane. Partition coefficients for anesthetic circuit components (masks, bellows, bags, airways, and circuit tubes) consistently ranked halothane greate...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Targ AG,Yasuda N,Eger EI 2nd

    更新日期:1989-08-01 00:00:00

  • Evaluation of residual neuromuscular block using train-of-four and double burst stimulation at the index finger.

    abstract::We examined the percentage of tactile detection of fade in response to train-of-four (TOF), double burst stimulation3,3 (DBS3,3), or DBS3,2 at the index finger compared with that at the thumb during continuous infusion of vecuronium. One hundred five adult patients were studied. At TOF ratios (T4/T1) of 0.41-0.70, fad...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验,收录出版

    doi:10.1097/00000539-199706000-00033

    authors: Saitoh Y,Nakazawa K,Makita K,Tanaka H,Amaha K

    更新日期:1997-06-01 00:00:00

  • Anesthetic and hemodynamic effects of single bolus versus incremental titration of hyperbaric spinal lidocaine through microcatheter.

    abstract::This study examined anesthetic development and hemodynamic changes during two techniques of hyperbaric lidocaine administration through 27-gauge intrathecal catheters for continuous spinal anesthesia in 55 elderly patients undergoing transurethral prostatic resection. Twenty-five patients were randomly assigned to rec...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1213/00000539-199407000-00022

    authors: Chan VW,Chung F,Gomez M,Seyone C,Baylon G

    更新日期:1994-07-01 00:00:00

  • The young: neuroapoptosis induced by anesthetics and what to do about it.

    abstract::Millions of human fetuses, infants, and children are exposed to anesthetic drugs every year in the United States and throughout the world. Anesthesia administered during critical stages of neurodevelopment has been considered safe and without adverse long-term consequences. However, recent reports provide mounting evi...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e3181c6b9ca

    authors: Creeley CE,Olney JW

    更新日期:2010-02-01 00:00:00

  • Cardiac function during intraperitoneal CO2 insufflation for aortic surgery: a transesophageal echocardiographic study.

    abstract::The effect of laparoscopy on cardiac function is controversial. We hypothesized that cardiac dysfunction related to increased afterload could be predominant in patients undergoing elective abdominal aortic repair. To test this hypothesis, we conducted a transesophageal echocardiographic study in 15 patients during lap...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000202473.17453.79

    authors: Alfonsi P,Vieillard-Baron A,Coggia M,Guignard B,Goeau-Brissonniere O,Jardin F,Chauvin M

    更新日期:2006-05-01 00:00:00

  • Nonuniform behavior of intravenous anesthetics on postischemic adhesion of neutrophils in the guinea pig heart.

    abstract:UNLABELLED:Adhesion of polymorphonuclear neutrophils (PMN) to the coronary endothelium is a crucial step in the development of ischemic myocardial injury. We tested the possible effects of six widely used IV anesthetics on non- and postischemic coronary adhesion of PMN in isolated perfused guinea pig hearts. Hearts (n ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200006000-00007

    authors: Szekely A,Heindl B,Zahler S,Conzen PF,Becker BF

    更新日期:2000-06-01 00:00:00

  • Malignant hyperthermia and muscular dystrophies.

    abstract:BACKGROUND:Patients with muscular dystrophy have been reported to experience a variety of life-threatening complications during and after general anesthesia. We performed a systematic analysis to define the spectrum of anesthetic-related complications in patients with muscular dystrophy, with an emphasis on malignant h...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,评审

    doi:10.1213/ane.0b013e3181aa5cf6

    authors: Gurnaney H,Brown A,Litman RS

    更新日期:2009-10-01 00:00:00

  • Presenting research information to children: a tale of two methods.

    abstract:BACKGROUND:Research information for children is often presented in a manner that is difficult to understand. We designed this study, therefore, to examine the effect of improved readability and processability of written study information on children's understanding. METHODS:One-hundred-ninety children aged 7-17 yr who...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/01.ane.0000270326.44507.11

    authors: Tait AR,Voepel-Lewis T,Malviya S

    更新日期:2007-08-01 00:00:00

  • Comparison of Thrombelastography-Derived Fibrinogen Values at Rewarming and Following Cardiopulmonary Bypass in Cardiac Surgery Patients.

    abstract:BACKGROUND:The inflated costs and documented deleterious effects of excess perioperative transfusion have led to the investigation of targeted coagulation factor replacement strategies. One particular coagulation factor of interest is factor I (fibrinogen). Hypofibrinogenemia is typically tested for using time-consumin...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章

    doi:10.1213/ANE.0000000000001465

    authors: Fabbro M 2nd,Gutsche JT,Miano TA,Augoustides JG,Patel PA

    更新日期:2016-09-01 00:00:00

  • Drugs to minimize perioperative blood loss in cardiac surgery: meta-analyses using perioperative blood transfusion as the outcome. The International Study of Peri-operative Transfusion (ISPOT) Investigators.

    abstract:UNLABELLED:Concern about the side effects of allogeneic red blood cell transfusion has increased interest in methods of minimizing perioperative transfusion. We performed meta-analyses of randomized trials evaluating the efficacy and safety of aprotinin, desmopressin, tranexamic acid, and epsilon-aminocaproic acid in c...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,meta分析

    doi:10.1097/00000539-199712000-00014

    authors: Laupacis A,Fergusson D

    更新日期:1997-12-01 00:00:00

  • The effects of pyrilamine and cimetidine on mRNA C-fos expression and nociceptive flinching behavior in rats.

    abstract:UNLABELLED:C-fos and Fos expression, frequently used as a neural nociceptive marker, is altered by many drugs. The effects of histamine receptor antagonists on c-fos messenger (m)RNA expression are unknown. We examined the effect of local and systemic administration of pyrilamine (H(1) receptor antagonist) and cimetidi...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000068883.63751.f8

    authors: Ashmawi HA,Chambergo FS,Araújo Palmeira CC,de Paula Posso I

    更新日期:2003-08-01 00:00:00

  • Epinephrine injection in lipid-based resuscitation from bupivacaine-induced cardiac arrest: transient circulatory return in rabbits.

    abstract:BACKGROUND:IV lipid emulsion has demonstrated to be effective therapy for bupivacaine-induced cardiotoxicity. However, the role of epinephrine when coadministered with lipid emulsion in toxin-induced cardiac arrest is unclear. We postulated superior resuscitation outcome in the absence of epinephrine in a rabbit model ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e3181e66050

    authors: Harvey M,Cave G,Prince G,Lahner D

    更新日期:2010-09-01 00:00:00