The current status of continuous noninvasive measurement of total, carboxy, and methemoglobin concentration.

abstract：:Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse events (i.e., platelet activation, decreased platelet count, febrile responses, changes in hemodynamic function). The Phase I studies described in this report were parallel, randomized, double-blinded, placebo-controlled studies condu...

journal_title：Anesthesia and analgesia

authors： Leese PT,Noveck RJ,Shorr JS,Woods CM,Flaim KE,Keipert PE

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine, a selective α2-adrenergic agonist currently approved for continuous intensive care unit sedation, is being widely evaluated for its role as a potential anesthetic. The closed-loop anesthesia delivery system (CLADS) is a method to automatically administer propofol total intravenous anesthesia...

journal_title：Anesthesia and analgesia

authors： Dutta A,Sethi N,Sood J,Panday BC,Gupta M,Choudhary P,Puri GD

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Postoperative nausea (PON) is a common complication of anesthesia and surgery. Antiemetic medication for higher-risk patients may reduce but does not reliably prevent PON. We examined aromatherapy as a treatment for patients experiencing PON after ambulatory surgery. Our primary hypothesis was that in compar...

journal_title：Anesthesia and analgesia

authors： Hunt R,Dienemann J,Norton HJ,Hartley W,Hudgens A,Stern T,Divine G

更新日期：2013-09-01 00:00:00

abstract：:We studied the pharmacokinetics of thiopental enantiomers in 14 healthy patients aged 37-73 yr receiving racemic thiopental by intravenous (IV) bolus or IV infusion. Plasma concentration of each enantiomer was measured by chiral high-performance liquid chromatography. After IV bolus, the total plasma clearance (CL) (2...

journal_title：Anesthesia and analgesia

authors： Nguyen KT,Stephens DP,McLeish MJ,Crankshaw DP,Morgan DJ

更新日期：1996-09-01 00:00:00

abstract：:We report a rare complication of spinal anesthesia-divergence paresis-which is characterized by an acquired horizontal diplopia at distance without evidence for abducens palsy. A 64-yr-old man underwent prostatectomy under spinal anesthesia with 2.5 mL of dibucaine hydrochloride 0.3% injected through a 20-gauge cuttin...

journal_title：Anesthesia and analgesia

authors： Arai M,Matsushima S,Terada H

更新日期：2006-06-01 00:00:00

abstract：UNLABELLED:Forty-eight healthy parturients scheduled for elective cesarean delivery were randomly allocated to receive intrathecally either 12 mg of hyperbaric bupivacaine plus 12.5 microg of fentanyl (n = 23) or bupivacaine alone (n = 25). In the latter group, IV 12.5 microg of fentanyl was administered immediately af...

journal_title：Anesthesia and analgesia

authors： Siddik-Sayyid SM,Aouad MT,Jalbout MI,Zalaket MI,Berzina CE,Baraka AS

更新日期：2002-07-01 00:00:00

abstract：:Dr. Paul Janssen was the founder of Janssen Pharmaceutica and the developer of over 80 pharmaceutical compounds that proved useful in human, botanical, and veterinary medicine. He and his coworkers synthesized the fentanyl family of drugs, many other potent analgesics, droperidol, etomidate, and numerous other importa...

journal_title：Anesthesia and analgesia

authors： Stanley TH,Egan TD,Van Aken H

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Neuromuscular blocking drugs have been implicated in intraoperative bronchoconstrictive episodes. We examined the effects of clinically relevant doses of cisatracurium and rocuronium on the lung mechanics of pediatric subjects. We hypothesized that cisatracurium and rocuronium would have bronchoconstrictive ...

journal_title：Anesthesia and analgesia

authors： Yang CI,Fine GF,Jooste EH,Mutich R,Walczak SA,Motoyama EK

更新日期：2013-12-01 00:00:00

abstract：:The suction-biopsy channel of a flexible bronchofiberscope was used to provide subglottic jet ventilation in six dogs and eight adult human subjects. In dogs, after 75 minutes of ventilation at a driving pressure of 2580 torr/cm2 (50 lb/in2) the PaO2 was 412 +/- 18 torr and the PaCO2 32 +/- 3 torr with a peak airway p...

journal_title：Anesthesia and analgesia

authors： Satyanarayana T,Capan L,Ramanathan S,Chalon J,Turndorf H

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:Perioperative major adverse cardiovascular and cerebrovascular events (MACCEs) are incompletely understood, and risk prediction is imprecise. Atherogenic leukocytes are crucial in cardiovascular events. However, it is unclear if surgical interventions affect leukocyte counts or activation status. Therefore, ...

journal_title：Anesthesia and analgesia

authors： Handke J,Scholz AS,Gillmann HJ,Janssen H,Dehne S,Arens C,Kummer L,Uhle F,Weigand MA,Motsch J,Larmann J

更新日期：2019-06-01 00:00:00

abstract：:Anesthesia information systems (AIS) record data from patient monitors and create a detailed electronic anesthesia record. Because the anesthesia record is a primary piece of evidence used in court during a malpractice proceeding, the ability to create an anesthesia record has fostered considerable debate concerning t...

journal_title：Anesthesia and analgesia

authors： Feldman JM

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Prolonged continuous oxytocin administration during labor may induce oxytocin receptor desensitization, which attenuates the response of the myometrium to further oxytocin, increasing the risk of postpartum hemorrhage. The literature comparing pulsatile (intermittent) versus continuous oxytocin administratio...

journal_title：Anesthesia and analgesia

authors： Talati C,Carvalho JCA,Luca A,Balki M

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Every facility that performs cases on holidays has in some way decided on its operating room (OR) and anesthesia staffing for holidays. Previous studies have not examined how best to calculate appropriate holiday staffing. METHODS:We analyzed weekend and holiday data from a university hospital. RESULTS:The...

journal_title：Anesthesia and analgesia

authors： Dexter F,Epstein RH

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Safe and effective alternatives are required in labor when epidural analgesia is not appropriate. We hypothesized that patient-controlled IV remifentanil labor analgesia would not be inferior to patient-controlled epidural labor analgesia. METHODS:This randomized nonblinded controlled noninferiority study i...

journal_title：Anesthesia and analgesia

authors： Stocki D,Matot I,Einav S,Eventov-Friedman S,Ginosar Y,Weiniger CF

更新日期：2014-03-01 00:00:00

abstract：:Phenylephrine and methoxamine are direct-acting, predominantly α(1) adrenergic receptor (AR) agonists. To better understand their physiologic effects, we screened 463 articles on the basis of PubMed searches of "methoxamine" and "phenylephrine" (limited to human, randomized studies published in English), as well as ci...

journal_title：Anesthesia and analgesia

authors： Thiele RH,Nemergut EC,Lynch C 3rd

更新日期：2011-08-01 00:00:00

abstract：:The acute central nervous and cardiovascular effects of the local anesthetics ropivacaine and bupivacaine were compared in 12 volunteers in a randomized double-blind manner with use of intravenous infusions at a rate of 10 mg/min up to a maximal dose of 150 mg. The volunteers were all healthy men. They were familiariz...

journal_title：Anesthesia and analgesia

authors： Scott DB,Lee A,Fagan D,Bowler GM,Bloomfield P,Lundh R

更新日期：1989-11-01 00:00:00

abstract：:Although clonidine has been shown to increase the duration of local anesthetic action and prolong postoperative analgesia when included in single-injection nerve blocks, a controlled investigation of the efficacy of this practice to improve analgesia for continuous perineural local anesthetic infusion has not been rep...

journal_title：Anesthesia and analgesia

authors： Ilfeld BM,Morey TE,Enneking FK

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Nerve injury can generate neuropathic pain. The accompanying mechanical allodynia may be reduced by the intrathecal administration of adenosine. The neuroprotective effects of adenosine are mediated by the adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channel. We assessed the relationship between...

journal_title：Anesthesia and analgesia

authors： Song JG,Hahm KD,Kim YK,Leem JG,Lee C,Jeong SM,Park PH,Shin JW

更新日期：2011-06-01 00:00:00

abstract：UNLABELLED:Reductions in cerebral venous oxyhemoglobin saturation (SjO2) occur during the rewarming phase of hypothermic cardiopulmonary bypass (CPB). We prospectively investigated the effects of propofol on these reductions in SjO2 (SjO2 <50%). Fiberoptic jugular bulb catheters were inserted in 30 patients undergoing ...

journal_title：Anesthesia and analgesia

authors： Souter MJ,Andrews PJ,Alston RP

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Tissue damage associated with surgery often produces peripheral and central sensitization that may outlast the stimuli, leading to exaggerated postoperative pain. Paradoxically, the use of opioid analgesia, which is essential for surgical pain management may induce pain sensitization leading to enhanced post...

journal_title：Anesthesia and analgesia

authors： Laboureyras E,Chateauraynaud J,Richebé P,Simonnet G

更新日期：2009-08-01 00:00:00

abstract：:We investigated the usefulness of peripheral flow index (PFI) measurement using a standard pulse oximetry digit probe for early prediction of successful regional blocks. Sixty-six patients scheduled for limb surgery underwent either axillary or sciatic block using a nerve stimulator technique with mepivacaine 1.5%. PF...

journal_title：Anesthesia and analgesia

authors： Galvin EM,Niehof S,Verbrugge SJ,Maissan I,Jahn A,Klein J,van Bommel J

更新日期：2006-07-01 00:00:00

abstract：:The hemodynamic effects of an induction dose of propofol, 2.5 mg/kg, or etomidate, 0.3 mg/kg, were studied in eight dogs. In addition, cardiodynamic changes were measured using a left ventricular catheter and needle force probes. Propofol was associated with significant decreases in systolic (19.9%) and diastolic (25....

journal_title：Anesthesia and analgesia

authors： Brüssel T,Theissen JL,Vigfusson G,Lunkenheimer PP,Van Aken H,Lawin P

更新日期：1989-07-01 00:00:00

abstract：:The ideal choice of a priming solution of the cardiopulmonary bypass (CPB) and its influence on the hemostatic system are not clear. Addition of albumin was reported to inhibit platelet damaging by blood-surface interactions ("coating"). To explore this possibility in 60 consecutive male patients undergoing elective a...

journal_title：Anesthesia and analgesia

authors： Boldt J,Zickmann B,Ballesteros BM,Stertmann F,Hempelmann G

更新日期：1992-02-01 00:00:00

abstract：:In certifying competence of anesthesiologists who have finished residency training, knowledge and judgment are evaluated objectively using written and oral examinations. Clinical motor skills, however, are not routinely assessed by objective techniques. This implicitly assumes that knowledge and judgment correlate wit...

journal_title：Anesthesia and analgesia

authors： Sivarajan M,Miller E,Hardy C,Herr G,Liu P,Willenkin R,Cullen B

更新日期：1984-06-01 00:00:00

abstract：:Catecholamine and serotonin concentrations in the cord, medulla, and hypothalamus were measured in rats after saline, after sufentanil sufficient to reduce the minimum alveolar concentration (MAC) of halothane by 30% or less, or after sufentanil sufficient to reduce the MAC of halothane by 80% or more. In the cord, hi...

journal_title：Anesthesia and analgesia

authors： Althaus JS,Miller ED Jr,Moscicki JC,Hecker BR,DiFazio CA

更新日期：1985-09-01 00:00:00

abstract：:Experimental aspiration pneumonitis studies in general have focused on the pathogenesis of the acidic component of the lung injury, although the injury produced by the particulate component of gastric contents largely has been ignored. The present study compares the inflammatory potential of small gastric particles to...

journal_title：Anesthesia and analgesia

authors： Knight PR,Rutter T,Tait AR,Coleman E,Johnson K

更新日期：1993-10-01 00:00:00

abstract：:Pregnancy is associated with an increased sensitivity to both general and local anesthetics. The exact reason is uncertain, but increased concentrations of progesterone and endogenous opiates have been implicated. Therefore, we tested the ability of intrathecally administered progesterone to produce analgesia and to p...

journal_title：Anesthesia and analgesia

authors： Jayaram A,Carp H

更新日期：1993-04-01 00:00:00

abstract：UNLABELLED:This study examines the effect of spinal ibuprofen on the behavioral manifestations associated with the opioid abstinence syndrome. Rats (n = 8 per group) were infused for 5 days with morphine and then pretreated with a spinal bolus dose of ibuprofen before systemic naloxone antagonism (300 microg). Groups i...

journal_title：Anesthesia and analgesia

authors： Dunbar SA,Karamov IG,Buerkle H

更新日期：2000-08-01 00:00:00

abstract：:The purpose of the present study was to assess patients' anxiety level and information requirement in the preoperative phase. During routine preoperative screening, 320 patients were asked to assess their anxiety and information requirement on a six-item questionnaire, the Amsterdam Preoperative Anxiety and Informatio...

journal_title：Anesthesia and analgesia

authors： Moerman N,van Dam FS,Muller MJ,Oosting H

更新日期：1996-03-01 00:00:00

abstract：:We considered the allocation of operating room (OR) time at facilities where the strategic decision had been made to increase the number of ORs. Allocation occurs in two stages: a long-term tactical stage followed by short-term operational stage. Tactical decisions, approximately 1 yr in advance, determine what specia...

journal_title：Anesthesia and analgesia

authors： Dexter F,Ledolter J,Wachtel RE

更新日期：2005-05-01 00:00:00