Lithium reduces maternal child abuse behaviour: a preliminary report.

abstract：WHAT IS KNOWN AND OBJECTIVE:This study developed a population pharmacokinetic (PK) model of levetiracetam (LEV) for treating neonatal seizures (NS) and determined the influence of clinically relevant covariates to explain the interindividual variability and residual error. METHODS:Twenty newborns admitted to the Neona...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Lima-Rogel V,López-López EJ,Medellín-Garibay SE,Gómez-Ruiz LM,Romero-Méndez C,Milán-Segovia RC,Romano-Moreno S

更新日期：2018-06-01 00:00:00

abstract：WHAT IS KNOW AND OBJECTIVE:Teriflunomide is indicated for the treatment of adult patients with relapsing-remitting multiple sclerosis. CASE SUMMARY:We present a rare intoxication with a high dose (672 mg) of teriflunomide. According to its product label, the only known treatment is the administration of colestyramine ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Mian P,van Haaften WT,Assink M,van Drie-Pierik RJHM

更新日期：2021-01-09 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Clinical pharmacokinetic profiles of clarithromycin and telithromycin in bronchopulmonary sites have not been fully characterized. This study aimed to describe in more detail the pharmacokinetics of the two macrolides in epithelial lining fluid (ELF) of human bronchi and to evaluate their ph...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ikawa K,Kikuchi E,Kikuchi J,Nishimura M,Derendorf H,Morikawa N

更新日期：2014-08-01 00:00:00

abstract：WHAT IS KNOWN:The increased risk of cardiovascular events in diabetic patients has been related to numerous metabolic and haemoreological factors. Some of these factors appear to be particularly evident during the post-prandial phases and to be related to peak plasma glucose level. AIM:To compare the effect of additio...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Derosa G,Mereu R,D'Angelo A,Salvadeo SA,Ferrari I,Fogari E,Gravina A,Palumbo I,Maffioli P,Randazzo S,Cicero AF

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Lactic acidosis is a rare, yet life-threatening adverse drug effect of highly active antiretroviral therapy (HAART), specifically stavudine and lamivudine. These nucleoside analogue reverse transcriptase inhibitors (NRTIs) are commonly used to treat patients infected with the human immunodeficiency virus (HI...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Marfo K,Garala M,Kvetan V,Gasperino J

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The anti-craving drug, naltrexone, is used as a pharmacotherapeutic adjunct in the treatment of alcohol dependence. In addictive disorders, compliance issues remain central. There are limited data on compliance with naltrexone treatment regimens within formalized rehabilitation programs and even less data th...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Feeney GF,Connor JP,Young RM,Tucker J,Czajkowski F

更新日期：2001-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Edoxaban has three dose adjustment factors (creatinine clearance, 15-50 mL/min; body weight, 60 kg or less; and concomitant medication with potent P-glycoprotein inhibitors) to prevent bleeding that results from elevated blood concentrations of the drug. A dose reduction (from 60 to 30 mg/da...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Takase T,Ikesue H,Nakagawa H,Kinoshita M,Muroi N,Kitai T,Furukawa Y,Hashida T

更新日期：2020-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Antituberculosis drug-induced liver injury (ATLI) is a serious adverse drug reaction, and its pathogenic mechanism is still largely unknown. Rifampin (RIF) has been reported to cause haemolysis due to the production of drug-dependent antibodies, and haemolysis results in an increased level o...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tao B,Yang M,Chen H,Pan H,Liu W,Yi H,Tang S

更新日期：2020-08-01 00:00:00

abstract：:Graft patency is a major factor contributing to the long-term results of coronary artery bypass graft (CABG) surgery. The systematic overview of the Antiplatelet Trialists' Collaboration provides unequivocal evidence that antiplatelet therapy reduces by nearly one-half the odds of coronary graft occlusion following CA...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Galea J,Manché A,Goiti JJ,Locke TJ,Wilkinson GA,Smith GH

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In our original study based on five monozygotic twin pairs and seven same-sex sib pairs, we previously showed that genetic factors contribute to body weight gain induced by the atypical antipsychotic clozapine. We aim to study this further by including patients treated with the atypical antipsy...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Gebhardt S,Theisen FM,Haberhausen M,Heinzel-Gutenbrunner M,Wehmeier PM,Krieg JC,Kühnau W,Schmidtke J,Remschmidt H,Hebebrand J

更新日期：2010-04-01 00:00:00

abstract：:A sensitive and specific high performance liquid chromatographic method (HPLC) was developed for measuring dopamine (DA) in human plasma samples. Dihydroxybenzylamine (DHBA) was employed as an internal standard. Following solvent extraction and separation on a C18 ion-pairing reversed phase column, the drug was detect...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Delval F,Dine T,Brunet C,Luyckx M,Gressier B,Cazin M,Cazin JC,Durocher A,Saulnier F

更新日期：1996-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The STOPP/START tool has been validated to assess elderly patients for potentially inappropriate prescribing. This study aimed to assess the effect of inclusion of a pharmacist on a physician-led ward round on potentially inappropriate prescribing in hospitalized elderly patients. METHODS:T...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Mulvogue K,Roberts JA,Coombes I,Cottrell N,Kanagarajah S,Smith A

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:To report the usefulness of antipsychotic dose-reduction for avoiding paralytic ileus in a patient with chronic schizophrenia and comorbid dementia. CASE SUMMARY:A 65-year-old in-patient developed severe paralytic ileus warranting a transfer to the general hospital. Constipation was very troublesome and he o...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Suzuki T,Uchida H,Watanabe K,Kashima H

更新日期：2007-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVES:To date, no case of headache has been reported with enoxaparin. We present the case of a 60-years-old man, who developed enoxaparin-induced throbbing headache and discuss the possible pharmacological mechanisms. We provide an analysis of enoxaparin-induced headache in three international da...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Brusadelli T,Carnovale C,Gentili M,Borsadoli C,Speziali A,Perrone V,Pellegrino P,Antoniazzi S,Pozzi M,Radice S,Clementi E

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:There is currently a lot of concern about the quality and therapeutic effectiveness of Mexican pharmaceutical products, and considerable price differences between alternative products containing the same active principle. OBJECTIVE:To establish whether four Mexican drug products, a high price and three lowe...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Hernández-Abad VJ,Castañeda-Hernández G,García-Jiménez S,Marroquín-Segura R,Sánchez-González E

更新日期：2008-06-01 00:00:00

abstract：:A drug use review of omeprazole was carried out at two centres in the Yorkshire Region from December 1990 to April 1991. Data collection documents were used and 66 patients in total were audited. Thirteen patients (19.7%) were treated for indications outside the product licence and 18 patients (27.3%) were treated for...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Norris CM,McManus PV,Petty D,Kay EA

更新日期：1992-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Mebendazole (MBZ) is a broad-spectrum antihelminthic agent of the benzimidazole type. Although MBZ has been reported to cause hepatic injury, case reports of severe hepatic injury are very rare. We report a case of severe hepatitis after administration of MBZ in a patient with Gilbert's synd...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tolomeo M,Colomba C,Meli M,Cascio A

更新日期：2019-12-01 00:00:00

abstract：:When designing studies of the optimal use of antimicrobial drugs, it is important to define at an early stage, which outcome parameters to use. It must be clear to which category a parameter to be measured belongs: the structure, the process or a clinical outcome. Attention must be paid to the measurement scales as we...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Natsch S,Kullberg BJ,Hekster YA,van der Meer JW

更新日期：2003-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Clinically validated pharmacogenomic information useful for patient selection and/or dose adjustment is included in drug labels. However, the label information may differ among countries. This commentary summarizes the pharmacogenomic information on drug labels in different countries. COMME...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Imatoh T,Sai K,Saito Y

更新日期：2018-08-01 00:00:00

abstract：:Flurbiprofen is a propionic acid-derived non-steroidal anti-inflammatory drug (NSAID) used widely in the treatment of rheumatism and non-arthritic pain. The pharmacokinetics of topically and orally administered flurbiprofen were compared in a two-part, open study involving healthy adult volunteers. In the first (cross...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Taburet AM,Singlas E,Glass RC,Thomas F,Leutenegger E

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVES:To determine the effects of temperature on binding characteristics of phenytoin to serum proteins in paediatric patients with epilepsy. METHOD:Serum samples examined in the study were obtained from 41 paediatric patients (23 male, 18 female) with epilepsy on phenytoin monotherapy. Their age ranged from 1 to...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kodama H,Kodama Y,Itokazu N,Shinozawa S,Kanemaru R,Sugimoto T

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:There is evidence that patients are being prescribed potentially hazardous drug-drug combinations in general practice despite the use of computerized drug interaction alert systems. One reason for this may be that general practitioners (GPs) are overriding these alerts without properly checking them. AIMS:(...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Magnus D,Rodgers S,Avery AJ

更新日期：2002-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Gabapentin has been used for the management of post-herpetic neuralgia (PHN). However, inconsistent results have been reported. This meta-analysis was performed to assess the efficacy and safety of gabapentin 1800 mg/day in PHN patients by conducting a meta-analysis. METHODS:Electronic data...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Fan H,Yu W,Zhang Q,Cao H,Li J,Wang J,Shao Y,Hu X

更新日期：2014-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The pharmacokinetic-pharmacodynamic parameter that best predicts the efficacy of vancomycin is the ratio of the area under the concentration versus time curve (AUC) to the minimum inhibitory concentration (MIC). A 24-h AUC (AUC24 )/MIC ratio ≥ 400 was recommended in an American consensus rev...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Fukumori S,Tsuji Y,Mizoguchi A,Kasai H,Ishibashi T,Iwamura N,To H

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To evaluate if once-daily dose (ODD) regimens of tobramycin attain pharmacodynamic goals using individualized pharmacokinetic monitoring of critically ill patients with creatinine clearance (Clcr) over 60 mL/min. METHODS:Fifty-one adult critically ill patients treated with intravenous tobramycin with ODD wer...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Peris-Marti JF,Borras-Blasco J,Rosique-Robles JD,Gonzalez-Delgado M

更新日期：2004-02-01 00:00:00

abstract：:The primary aim of this study was to assess patterns of prescribing of analgesic medications in a primary care setting in South Africa. Medication records of 47,103 patients for the year 1995 were retrospectively reviewed. Analgesic agents represented 12.3% of the total number and 14.2% of the total cost of all the pr...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Truter I

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Boric acid is generally not recognized as a poisonous substance. However, boric acid has potentially fatal actions such as hypotension, metabolic acidosis and oliguria. Death may result from circulation collapse and shock. OBJECTIVE:We present a clinical case history of the successful use of forced diuresis...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Teshima D,Taniyama T,Oishi R

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the effect of diluent type, storage conditions and the nature of package on the stability of reconstituted Parecoxib sodium for injection (PSI). METHODS:Parecoxib sodium for injection is a lyophilized product for single use. It is intended for the management of acute...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Crane IM,Mulhern MG,Nema S

更新日期：2003-10-01 00:00:00

abstract：:The extent and factors that influence drug use were studied in two rural cohorts of Finnish men. The men aged between 65 and 84 years belonged to the Finnish study population of the 25-year follow-up of the 'Seven Countries Study'. Of the original 1,711 men in 1959, 766 were still alive in 1984. The participation rate...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Enlund H,Martikainen J,Turakka H,Nissinen A

更新日期：1990-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Far more patients are now surviving cancer than ever before because of major advances in the diagnosis and treatment of primary and metastatic malignancy. Adjuvant chemotherapeutic drug and combination regimens have contributed to the success. However, persistent residual adverse effects inv...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Raffa RB

更新日期：2011-08-01 00:00:00