当前位置： SCI文献检索 > JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS期刊下所有文献 > Omission of aspirin in patients following coronary artery bypass graft surgery.

Omission of aspirin in patients following coronary artery bypass graft surgery.

Abstract：

:Graft patency is a major factor contributing to the long-term results of coronary artery bypass graft (CABG) surgery. The systematic overview of the Antiplatelet Trialists' Collaboration provides unequivocal evidence that antiplatelet therapy reduces by nearly one-half the odds of coronary graft occlusion following CABG. We retrospectively reviewed patients undergoing CABG during 1993 at the Cardiothoracic Unit, Northern General Hospital, to determine the incidence of, and indications for, aspirin omission following CABG: 462 patients with isolated CABG, 75 patients with a combined CABG and a heart valve procedure and 21 patients with a combined CABG and other non-valve procedure. Thirty-six patients (7.5%) with isolated CABG and CABG combined with a non-valve procedure were not prescribed aspirin. The reasons for aspirin omission were categorized into three groups depending on whether omission was fully justified (group 1), possibly justified (group 2) or unjustified (group 3). Twenty-one patients were in groups 2 and 3, nine of whom were started on aspirin 2-6 weeks after discharge without any ill effect. Forty-two patients were discharged from hospital on a three month course of warfarin. Four months later four patients had died, 24 had changed to aspirin, 10 were still on warfarin and four were on neither drug. Aspirin was sometimes omitted without clear indications. Better provisions for supervision should be made by either the General Practitioner or Hospital Practitioner during the change-over period from oral anticoagulation to antiplatelet therapy in patients on a short course of warfarin.

journal_name

J Clin Pharm Ther

journal_title

Journal of clinical pharmacy and therapeutics

authors

Galea J,Manché A,Goiti JJ,Locke TJ,Wilkinson GA,Smith GH

doi

10.1111/j.1365-2710.1994.tb00697.x

subject

Has Abstract

pub_date

1994-12-01 00:00:00

pages

381-6

issue

6

eissn

0269-4727

issn

1365-2710

journal_volume

19

pub_type

杂志文章

相关文献

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS文献大全
  • Linezolid and the risk of lactic acidosis: Data mining and analysis of the FDA Adverse Event Reporting System.

    abstract：WHAT IS KNOWN AND OBJECTIVE:Lactic acidosis (LA) is a rare but potentially lethal side effect of linezolid (LZD). However, limited by the study population, the number of patients with LA is insufficient to summarize all the clinical characteristics and risk factors. METHODS:We evaluated the association between LZD and...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/jcpt.13245

    authors： Dai Y,Wang Y,Zeng Y,Zhang C,Zhou Z,Shi D

    更新日期：2020-12-01 00:00:00

  • The impact of a computerized physician order entry system on medical errors with antineoplastic drugs 5 years after its implementation.

    abstract：WHAT IS KNOWN AND OBJECTIVE:Computerized physician order entry (CPOE) systems reduce medical errors (MEs). Nevertheless, a CPOE system may also lead to new types of errors, especially when it is first implemented. The objectives of this study were to determine the impact of a CPOE on the number of MEs and to identify t...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/jcpt.12305

    authors： Sanchez Cuervo M,Rojo Sanchis A,Pueyo Lopez C,Gomez de Salazar Lopez de Silanes E,Gramage Caro T,Bermejo Vicedo T

    更新日期：2015-10-01 00:00:00

  • Distribution of CYP2C19*17 allele and genotypes in an Indian population.

    abstract：WHAT IS KNOWN AND OBJECTIVE:CYP2C19*17 allele increases the metabolic activity of CYP2C19 resulting in decreased therapeutic levels of CYP2C19 substrates. There exist inter-ethnic differences in the distribution of this allele. The present study was aimed at establishing the allele and genotype frequencies of CYP2C19*1...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2710.2011.01294.x

    authors： Anichavezhi D,Chakradhara Rao US,Shewade DG,Krishnamoorthy R,Adithan C

    更新日期：2012-06-01 00:00:00

  • Comparison of single-point phenytoin dosage prediction techniques.

    abstract：:To dose the anticonvulsant phenytoin (PHT) in a clinical situation is difficult because of the non-linear metabolism of the drug. Therefore many techniques have been advocated to aid dosage adjustments based on a single-point PHT concentration determined at steady-state (ss). We retrospectively investigated six method...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2710.1988.tb00196.x

    authors： Yukawa E,Higuchi S,Ohtsubo K,Aoyama T

    更新日期：1988-08-01 00:00:00

  • Scope of new formulation approaches in the repurposing of pioglitazone for the management of Alzheimer's disease.

    abstract：WHAT IS KNOWN AND OBJECTIVE:Alzheimer's disease (AD) is the most common cause of dementia among the elderly. The exact cause of the disease is not clearly known, and no existing therapies are able to prevent disease progression. Identification of the possible "impaired brain insulin signalling in AD" enriched the scope...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/jcpt.12808

    authors： Jojo GM,Kuppusamy G

    更新日期：2019-06-01 00:00:00

  • Investigation of bioequivalence of a new fixed-dose combination of acarbose and metformin with the corresponding loose combination as well as the drug-drug interaction potential between both drugs in healthy adult male subjects.

    abstract：WHAT IS KNOWN AND OBJECTIVE:Both metformin and acarbose are recommended monotherapy and add-on therapy in type 2 diabetes mellitus (T2DM). A fixed-dose combination (FDC) of acarbose and metformin has been developed to reduce pill burden and potentially improve compliance. The current study investigated the bioequivalen...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/jcpt.12166

    authors： Kim S,Jang IJ,Shin D,Shin DS,Yoon S,Lim KS,Yu KS,Li J,Zhang H,Liu Y,Brendel E,Blode H,Wang Y

    更新日期：2014-08-01 00:00:00

  • Post-marketing safety-related regulatory actions on first-in-class drugs: A double-cohort study.

    abstract：WHAT IS KNOWN AND OBJECTIVE:New first-in-class (FIC) drugs with novel mechanisms of action may be highly effective, but lack adequate safety information, and therefore may be associated with crucial post-marketing safety issues. The objective of this study was to evaluate the post-marketing risk of FIC drug with compar...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/jcpt.13096

    authors： Ikeda J,Kaneko M,Narukawa M

    更新日期：2020-06-01 00:00:00

  • Effect of delayed and/or missed enteric-coated divalproex doses on valproic acid concentrations: simulation and dose replacement recommendations for the clinician.

    abstract：BACKGROUND AND OBJECTIVE:Enteric-coated, delayed-release divalproex sodium requires multiple daily administrations and high adherence rate to prevent breakthrough seizures and control adverse effects. We evaluated the effect of missing one or two doses of divalproex for up to 24 h, followed by replacement and resumptio...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2710.2006.00739.x

    authors： Dutta S,Reed RC

    更新日期：2006-08-01 00:00:00

  • Determinants of prescribing costs amongst single-handed general practitioners.

    abstract：OBJECTIVE:To investigate the contribution of patient and doctor characteristics in explaining observed variations in prescribing costs between individual doctors. METHOD:Secondary analysis of data collected from general practitioners, Family Health Services Authorities, 1991 Census data set and the Prescription Pricin...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1046/j.1365-2710.2001.00371.x

    authors： Gill PS,Roalfe A

    更新日期：2001-12-01 00:00:00

  • Drug-use pattern of Chinese herbal medicines in insomnia: a 4-year survey in Taiwan.

    abstract：BACKGROUND AND OBJECTIVE:Insomnia is a common complaint in the general population. Interest in the use of alternative treatments for insomnia is increasing exponentially and is fairly common in Taiwan. We undertook a survey to define the drug utilization patterns of Chinese herbal medicines (CM) for insomnia in Taiwan....

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2710.2009.01038.x

    authors： Chen LC,Chen IC,Wang BR,Shao CH

    更新日期：2009-10-01 00:00:00

  • Echinacea purpurea along with zinc, selenium and vitamin C to alleviate exacerbations of chronic obstructive pulmonary disease: results from a randomized controlled trial.

    abstract：WHAT IS KNOWN AND OBJECTIVE:Upper respiratory tract infections (URTI) frequently cause exacerbations of chronic-obstructive pulmonary disease (COPD). Stimulation of the innate immune system may provide an early defence against such infections. The objective of this study was to determine whether Echinacea purpurea (EP)...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/j.1365-2710.2010.01212.x

    authors： Isbaniah F,Wiyono WH,Yunus F,Setiawati A,Totzke U,Verbruggen MA

    更新日期：2011-10-01 00:00:00

  • Does levodopa improve swallowing dysfunction in Parkinson's disease patients?

    abstract：OBJECTIVE:To assess the influence of levodopa on swallowing dysfunction in Parkinson's disease patients. METHODS:A systematic review of the literature and a meta-analysis were performed. All studies referring to levodopa and swallowing dysfunction that provided direct data or data that could be transformed into mean +...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章,meta分析

    doi：10.1111/j.1365-2710.2009.01031.x

    authors： Menezes C,Melo A

    更新日期：2009-12-01 00:00:00

  • Microbial contamination and preservative efficacy of topical creams.

    abstract：:Nineteen different brands of topical creams were tested in duplicate for microbial growth. The efficacy of their preservation was assessed, when possible, by standard pharmacopoeial procedures. Microbial growth was demonstrated in cultures from all specimens. However, high counts (> 10(4) c.f.u./g) were obtained from ...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2710.1994.tb00808.x

    authors： Na'was T,Alkofahi A

    更新日期：1994-02-01 00:00:00

  • Population pharmacokinetics of ABT-594 in subjects with diabetic peripheral neuropathic pain.

    abstract：WHAT IS KNOWN AND OBJECTIVE:ABT-594 is a non-opioid, non-NSAID analgesic. The objective of this work was to characterize the population pharmacokinetics of ABT-594 in subjects with neuropathic pain. METHODS:Efficacy, safety and pharmacokinetics of ABT-594 in subjects with painful diabetic polyneuropathy were evaluated...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1111/j.1365-2710.2011.01325.x

    authors： Dutta S,Awni W

    更新日期：2012-08-01 00:00:00

  • Development of a novel algorithm for detecting glucocorticoid-induced diabetes mellitus using a medical information database.

    abstract：WHAT IS KNOWN AND OBJECTIVE:Glucocorticoid-induced diabetes mellitus (GIDM) increases the risk of diabetes mellitus (DM)-related complications but is generally difficult to detect in clinical settings. The criteria for diagnosing GIDM have not been established. Recently, medical information databases (MIDs) have been u...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/jcpt.12499

    authors： Imatoh T,Sai K,Hori K,Segawa K,Kawakami J,Kimura M,Saito Y

    更新日期：2017-04-01 00:00:00

  • Sleep quality and the use of benzodiazepine hypnotics in general practice.

    abstract：:The aim of the study was to determine the usage patterns of benzodiazepine hypnotics, the use of other ways of improving sleep and general sleep characteristics in patients prescribed these drugs on a regular basis and in a control group of age- and sex-matched patients not receiving hypnotics. Patients receiving regu...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2710.1995.tb00634.x

    authors： Krska J,MacLeod TN

    更新日期：1995-04-01 00:00:00

  • HbA1C as a marker of retrograde glycaemic control in diabetes patient with co-existed beta-thalassaemia: A case report and a literature review.

    abstract：WHAT IS KNOWN AND OBJECTIVE:The HbA1C marker used in assessing diabetes control quality is not sufficient in diabetes patients with thalassaemia. CASE DESCRIPTION:A male diabetic patient with thalassaemia was hospitalized due to distal neuropathic pain, right toe trophic ulcer, unacceptable five-point glycaemic profil...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/jcpt.13073

    authors： Gluvic Z,Obradovic M,Lackovic M,Samardzic V,Tica Jevtic J,Essack M,Bajic VB,Isenovic ER

    更新日期：2020-04-01 00:00:00

  • Pharmacokinetics of intravenous midazolam during epidural anaesthesia.

    abstract：:Midazolam concentration curves versus time were analysed in 10 otherwise healthy patients (ASA I-II) with inferior limb pathologies. The benzodiazepine was used as an adjuvant agent to epidural anaesthesia in view of its lower residual effect compared with other intravenous benzodiazepines. Midazolam pharmacokinetics...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2710.1991.tb00306.x

    authors： Sánchez-Alcaraz A,Sangrador G,Laguarda M,Quintana B

    更新日期：1991-06-01 00:00:00

  • Serum vitamin E level in patients with breast cancer.

    abstract：:In this study, the serum vitamin E (total tocopherol) levels in patients with breast cancer (n = 100) and healthy controls (n = 70) were measured. The mean values for vitamin E were found to be 0.44 mg/100 ml in breast cancer patients and 1.108 mg/100 ml in controls. In the statistical evaluation, the vitamin E levels...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2710.1995.tb00645.x

    authors： Torun M,Akgül S,Sargin H

    更新日期：1995-06-01 00:00:00

  • Long-term stability of vancomycin hydrochloride in intravenous infusions.

    abstract：BACKGROUND AND OBJECTIVE:Vancomycin is often used in antibiotic infusions for hospitalized patients and it is advantageous to prepare such intravenous solutions in advance. The objective of this study was to investigate the long-term stability of this antibiotic stored at 4 degrees C in polyvinyl chloride (PVC) bags. ...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2710.1997.tb00018.x

    authors： Galanti LM,Hecq JD,Vanbeckbergen D,Jamart J

    更新日期：1997-10-01 00:00:00

  • Stability and compatibility of anakinra with ceftriaxone sodium injection in 0.9% sodium chloride or 5% dextrose injection.

    abstract：:The stability and compatibility of anakinra (recombinant human interleukin-1 receptor antagonist) with ceftriaxone sodium in 0.9% sodium chloride or 5% dextrose injection was determined during a 4-h period at ambient room temperature and light. Anakinra was diluted in 0.9% sodium chloride or 5% dextrose to the concent...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1046/j.1365-2710.1997.95275952.x

    authors： Nahata MC,Morosco RS,Sabados BK,Weber TR

    更新日期：1997-06-01 00:00:00

  • The chemical and pharmaceutical equivalence of sulphadoxine/pyrimethamine tablets sold on the Tanzanian market.

    abstract：:This study investigated chemical and pharmaceutical equivalence of 11 brands of pyrimethamine-sulphadoxine combination tablets sold on the Tanzanian market. Physical and chemical tests were performed for all the 11 brands. These tests included hardness test, friability, disintegration, dissolution, weight uniformity a...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2710.2005.00687.x

    authors： Hebron Y,Tettey JN,Pournamdari M,Watson DG

    更新日期：2005-12-01 00:00:00

  • Exacerbation of psoriatic skin lesions in a patient with psoriatic arthritis receiving adalimumab.

    abstract：OBJECTIVE:To report a case of a patient with psoriatic arthritis (PsA) receiving adalimumab, who developed an exacerbation of palmoplantaris pustulosa psoriasis. CASE SUMMARY:A 38-year-old woman diagnosed with PsA had received treatment with non-steroidal antiinflammatory drugs. Two months prior to admission, the pati...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2710.2008.00915.x

    authors： Borrás-Blasco J,Gracia-Perez A,Nuñez-Cornejo C,Rosique-Robles JD,Mateu-Puchades A,Casterá MD,Rubio-Fabra M

    更新日期：2008-06-01 00:00:00

  • A phase I trial assessing the safety, tolerability, pharmacokinetic and pharmacodynamic characteristics of single-dose Auron Misheil therapy in healthy male subjects.

    abstract：BACKGROUND AND OBJECTIVE:Auron Misheil therapy (AMT) is a combination of widely used pharmaceuticals and herbal components that has been used since the 1980s as a supportive therapy, mainly in end-stage cancer patients on a compassionate basis. This phase I study was conducted to assess the safety, tolerability, and ph...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2710.2009.01087.x

    authors： Scheele J,Diergarten K,Drevs J,Niazi FR

    更新日期：2013-02-01 00:00:00

  • New medicines in primary care: a review of influences on general practitioner prescribing.

    abstract：BACKGROUND AND OBJECTIVE:The uptake of new medicines is slower in the UK than in many other countries. Previous research found that cost and price have little influence on general practitioner (GP) behaviour, but recent UK government policy may have heightened cost-consciousness. Focussing on new medicines, this review...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/j.1365-2710.2008.00875.x

    authors： Mason A

    更新日期：2008-02-01 00:00:00

  • Theophylline plasma clearance in critically ill geriatric patients receiving total parenteral nutrition and in control patients.

    abstract：:Mean values and standard deviations are reported for theophylline plasma clearance in 45 hospitalized geriatric patients (age greater than 65 years), distributed into two groups: Group I (n = 24) included critically ill patients admitted to the ICU on total parenteral nutrition (TPN). Group II (n = 21) included patien...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2710.1990.tb00385.x

    authors： Sangrador G,Sánchez-Alcaraz A,Ubeda R,Ibañez P

    更新日期：1990-08-01 00:00:00

  • Heparin-induced acute adverse reaction--case report of a patient with acute trauma and a genetic predisposition to thrombotic events: a concurrence of events.

    abstract：WHAT IS KNOWN AND OBJECTIVE:The most common complication of heparin therapy is bleeding. Allergic reactions to heparin are rare, and the mechanisms are poorly understood. We report on a case of acute systemic reaction after subcutaneous injections of a low-molecular-weight heparin (LMWH) in a patient with a genetic pre...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/j.1365-2710.2012.01360.x

    authors： Leone S,Zuccoli ML,Fucile C,Storace S,Martelli A,Mattioli F

    更新日期：2012-12-01 00:00:00

  • Phytotherapeutics: an evaluation of the potential of 1000 plants.

    abstract：OBJECTIVE:The aim of this review is to evaluate and summarize the available scientific information on the commonest plant extracts marketed in Western countries. In view of the intense, ongoing search for new plant extracts with powerful anti-inflammatory activity, we paid particular attention to this topic. The aim is...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/j.1365-2710.2009.01096.x

    authors： Cravotto G,Boffa L,Genzini L,Garella D

    更新日期：2010-02-01 00:00:00

  • Retinoic acid syndrome: a review.

    abstract：:The retinoic acid syndrome (RAS) is an unpredictable but frequent complication which may develop after administration of all-trans retinoic acid (ATRA) most commonly in patients with acute promyelocytic leukaemia (APL). In this review, we describe the incidence, predictive factors, clinical course, outcome and treatme...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/j.1365-2710.2008.00935.x

    authors： Patatanian E,Thompson DF

    更新日期：2008-08-01 00:00:00

  • Clinically significant drug-drug interaction between tacrolimus and fluconazole in stable renal transplant recipient and literature review.

    abstract：WHAT IS KNOWN AND OBJECTIVE:Clinical use of fluconazole against fungal infections in renal transplant patients is complicated by the potentially marked and unpredictable drug-drug interactions (DDIs). We report a case of tacrolimus-fluconazole DDI in a stable renal transplant recipient and describe the mechanism, magni...

    journal_title：Journal of clinical pharmacy and therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/jcpt.13075

    authors： He J,Yu Y,Yin C,Liu H,Zou H,Ma J,Yang W,Liu Y,Zhong L,Chen X

    更新日期：2020-04-01 00:00:00