Determinants of prescribing costs amongst single-handed general practitioners.

abstract：WHAT IS KNOWN AND OBJECTIVE:Edoxaban has three dose adjustment factors (creatinine clearance, 15-50 mL/min; body weight, 60 kg or less; and concomitant medication with potent P-glycoprotein inhibitors) to prevent bleeding that results from elevated blood concentrations of the drug. A dose reduction (from 60 to 30 mg/da...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Takase T,Ikesue H,Nakagawa H,Kinoshita M,Muroi N,Kitai T,Furukawa Y,Hashida T

更新日期：2020-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Therapeutic effects of anti-VEGF agents, corticosteroids and laser therapy have been previously examined for treating macular oedema secondary to branch and central retinal vein occlusion (BRVO and CRVO). However, anti-VEGF efficacy has not been previously compared to corticosteroid or laser...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Qian T,Zhao M,Xu X

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There is concern regarding long-term excess calcium intake in end-stage renal disease populations. Because calcium carbonate is an over-the-counter (OTC) medication, few studies have been able to track its use. The Veterans Health Administration (VA) tracks national pharmacy data for both OTC a...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Borzecki AM,Lee A,Wang SW,Brenner L,Kazis LE

更新日期：2007-12-01 00:00:00

abstract：:The effects of age and co-medication on steady-state phenobarbital (PB) level-dose (L/D) ratios were evaluated retrospectively in 539 paediatric patients. The PB L/D ratio increased significantly with age up to 15 years. Associated anti-epileptic therapy affected the PB L/D ratio, which was significantly increased in ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Yukawa E,Higuchi S,Aoyama T

更新日期：1992-08-01 00:00:00

abstract：:Isolated human mononuclear cells exposed to either lipopolysaccharide or Staphylococcus aureus secreted interleukin-1 like material. The secretion was concentration dependent. The minimal detectable level in the test solution of lipopolysaccharide and Staphylococcus aureus was 200 pg/ml and 10(5) cells/ml respectively...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Hansen EW,Christensen JD

更新日期：1990-12-01 00:00:00

abstract：:When designing studies of the optimal use of antimicrobial drugs, it is important to define at an early stage, which outcome parameters to use. It must be clear to which category a parameter to be measured belongs: the structure, the process or a clinical outcome. Attention must be paid to the measurement scales as we...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Natsch S,Kullberg BJ,Hekster YA,van der Meer JW

更新日期：2003-12-01 00:00:00

abstract：:Caffeine elimination was studied in 73 patients admitted to an intensive care unit, 33 of whom had liver disease. Mean plasma clearance of caffeine in patients with no liver disease (1.30 +/- 0.79 ml/kg/min) was significantly higher than in patients with liver disease (0.39 +/- 0.23 ml/kg/min). Mean half-life of caffe...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Calatayud O,Rodríguez M,Sánchez-Alcaraz A,Ibáñez P

更新日期：1995-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Aloe vera (Aloe vera (L.) Burm.f., Xanthorrhoeaceae family) has long been used in folk or traditional medicine for diabetes. Several studies have been conducted on the effect of Aloe vera on glycaemic control, but the results appear inconsistent. We undertook a systematic review and meta-ana...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Suksomboon N,Poolsup N,Punthanitisarn S

更新日期：2016-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Computerized physician order entry (CPOE) systems reduce medical errors (MEs). Nevertheless, a CPOE system may also lead to new types of errors, especially when it is first implemented. The objectives of this study were to determine the impact of a CPOE on the number of MEs and to identify t...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Sanchez Cuervo M,Rojo Sanchis A,Pueyo Lopez C,Gomez de Salazar Lopez de Silanes E,Gramage Caro T,Bermejo Vicedo T

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Ropivacaine hydrochloride (HCl) ('Naropin') is a long-acting local anaesthetic agent, administered epidurally to patients undergoing various surgical procedures. A combination of local anaesthetic and opioid is often administered for the management of severe pain to ensure that a minimal dose of each is used...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Oster Svedberg K,McKenzie J,Larrivee-Elkins C

更新日期：2002-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:There is increasing evidence that epigenetics plays a major role in the pathogenesis of the idiopathic mental disorders. This article comments on the role of epigenetics in the pharmacotherapy, psychotherapy and nutritional management of these disorders. COMMENT:There are two classes of epi...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Peedicayil J

更新日期：2012-10-01 00:00:00

abstract：WHAT IS KNOWN:The increased risk of cardiovascular events in diabetic patients has been related to numerous metabolic and haemoreological factors. Some of these factors appear to be particularly evident during the post-prandial phases and to be related to peak plasma glucose level. AIM:To compare the effect of additio...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Derosa G,Mereu R,D'Angelo A,Salvadeo SA,Ferrari I,Fogari E,Gravina A,Palumbo I,Maffioli P,Randazzo S,Cicero AF

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To assess the influence of levodopa on swallowing dysfunction in Parkinson's disease patients. METHODS:A systematic review of the literature and a meta-analysis were performed. All studies referring to levodopa and swallowing dysfunction that provided direct data or data that could be transformed into mean +...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Menezes C,Melo A

更新日期：2009-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Adverse drug events (ADE), common and underestimated in ICU patients, have direct consequences on length of stay, mortality and hospital costs. Critically ill patients with HIV/AIDS are at a high risk of ADE because of their need for multiple drug therapies. ADE can be prevented, especially ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ramos GV,Guaraldo L,Japiassú AM,Bozza FA

更新日期：2015-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Tacrolimus, a widely used immunosuppressive agent in organ transplantation, has a narrow therapeutic window. It has been suggested that its interaction with lansoprazole could be dependent on polymorphisms of CYP3A5 and CYP2C19. The objective of this study was to investigate how, 1 year afte...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Miura M,Niioka T,Kagaya H,Saito M,Hayakari M,Habuchi T,Satoh S

更新日期：2011-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Appraisal of drug information centres (DICs) is mainly by word of mouth communication and surveys of overall user satisfaction. Efforts to study the impact of this type of informatics and decision support systematically are generally lacking within the healthcare system. COMMENT:Scandinavia...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Schjøtt J,Spigset O

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Vancomycin is often used in antibiotic infusions for hospitalized patients and it is advantageous to prepare such intravenous solutions in advance. The objective of this study was to investigate the long-term stability of this antibiotic stored at 4 degrees C in polyvinyl chloride (PVC) bags. ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Galanti LM,Hecq JD,Vanbeckbergen D,Jamart J

更新日期：1997-10-01 00:00:00

abstract：:The paper describes an in-depth study of the parenteral fat emulsions, Intralipid 20% and Ivelip 20%. A large number of emulsion samples from separate containers and batches was sampled. The parameters measured were droplet size (both by photon correlation and laser diffraction), pH and zeta potential. These parameter...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Washington C,Koosha F,Davis SS

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:Renal function was estimated in 129 elderly patients with methicillin-resistant Staphylococcus aureus (MRSA) who were treated with vancomycin (VCM). The estimation was performed by substituting serum creatinine (SCR) measured enzymatically and a value converted using the Jaffe method into the Cockcroft-Gault ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tsuji Y,Hiraki Y,Mizoguchi A,Sadoh S,Sonemoto E,Kamimura H,Karube Y

更新日期：2009-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The CHOP regimen with rituximab (R-CHOP) remains the standard for chemotherapy in patients with aggressive non-Hodgkin's lymphoma (NHL). The cardiotoxicity of doxorubicin appears to be a key problem in clinical practice. We studied the cardiotoxicity of CHOP/R-CHOP regimen in a retrospective...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Limat S,Daguindau E,Cahn JY,Nerich V,Brion A,Perrin S,Woronoff-Lemsi MC,Deconinck E

更新日期：2014-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Clinical pharmacists actively participate in patient care via patients' medication use. Yet the setting of Coronavirus Disease 2019 (COVID-19) limits patient contact with healthcare personnel. We aimed to review the services provided and drug-related problems detected using telemonitoring me...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Surapat B,Sungkanuparph S,Kirdlarp S,Lekpittaya N,Chunnguleum K

更新日期：2021-02-01 00:00:00

abstract：:Standard meta-analytical and pharmacoeconomic techniques were used to study the clinical effectiveness and the cost-effectiveness ratio of the prophylactic (or pre-emptive) administration of G-CSF to patients with small cell lung cancer treated with conventional myelosuppressive cytotoxic chemotherapy. In the first pa...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Messori A,Trippoli S,Tendi E

更新日期：1996-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Nephrotoxicity is a recognized side effect of cisplatin chemotherapy. However, the optimal strategy for preventing cisplatin-induced nephrotoxicity, if any, remains unclear. The primary objective for this study was to determine whether mannitol or furosemide provides better nephroprotection ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Mach CM,Kha C,Nguyen D,Shumway J,Meaders KM,Ludwig M,Williams-Brown MY,Anderson ML

更新日期：2017-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Moringa oleifera (MO) Lam (Moringaceae) is commonly used as food supplement and as medicine in most African countries where malaria is also endemic. Therefore, co-administration of MO with antimalarials is a possibility. This study investigated the effects of MO leaves powder on the pharmaco...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Olawoye OS,Adeagbo BA,Bolaji OO

更新日期：2018-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Upper respiratory tract infections (URTI) frequently cause exacerbations of chronic-obstructive pulmonary disease (COPD). Stimulation of the innate immune system may provide an early defence against such infections. The objective of this study was to determine whether Echinacea purpurea (EP)...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Isbaniah F,Wiyono WH,Yunus F,Setiawati A,Totzke U,Verbruggen MA

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To describe the current practice of Israeli paediatricians regarding acetaminophen dosing. METHODS:A cross-sectional survey among 200 paediatricians. The paediatricians were questioned of the recommended dose of acetaminophen, and whether they give prescriptions for acetaminophen and instruct their patients ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Greenberg R,Grossman Z,Goldstein L,Berkovitch M,Kozer E

更新日期：2005-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The 4-factor prothrombin complex concentrate (4F-PCC) may be used to emergently achieve haemostasis in patients on anticoagulation prior to surgery. Limited data exist using the intraosseous route of administration of 4F-PCC in patients taking factor Xa inhibitors. CASE DESCRIPTION:We descr...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ratliff P,Nutley K,Schroeder W,Cottingham L

更新日期：2020-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Metronidazole is one of the drugs with a well-recognized potential to rarely cause acute pancreatitis. The relation of other drugs of the 5-aminoimidazole group (e.g. tinidazole) to acute pancreatitis remains unknown. For the treatment of protozoal infections, tinidazole may be considered as...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Hegazi MO,Saleh F,John JE

更新日期：2015-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Ticagrelor is a reversibly binding and selective P2Y12 -receptor antagonist approved for the prevention of atherothrombotic events in patients with acute coronary syndromes. As bleeding events remain a hazard with antiplatelet therapy, this study investigated the effect of the vasopressin ag...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Teng R,Mitchell PD,Butler K

更新日期：2014-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Anti-tuberculosis drug-induced liver injury (ATLI) is one of the most significant adverse reactions for this line of therapy. N-acetyltransferase 2 (NAT2) is an important metabolic enzyme involved in drug metabolism and detoxification. Genetic polymorphism and DNA methylation have been prove...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Zhang D,Hao J,Hou R,Yu Y,Hu B,Wei L

更新日期：2020-06-01 00:00:00