Physicochemical properties of parenteral fat emulsions containing 20% triglyceride; Intralipid and Ivelip.

abstract：WHAT IS KNOWN AND OBJECTIVE:The STOPP/START tool has been validated to assess elderly patients for potentially inappropriate prescribing. This study aimed to assess the effect of inclusion of a pharmacist on a physician-led ward round on potentially inappropriate prescribing in hospitalized elderly patients. METHODS:T...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Mulvogue K,Roberts JA,Coombes I,Cottrell N,Kanagarajah S,Smith A

更新日期：2017-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Long non-coding RNAs (lncRNAs) have been proved to regulate. LncRNA TUG1 is well characterized in cancer biology. This study was carried out to investigate the molecular function of lncRNA TUG1 in myocardial infarction. METHODS:This study enrolled 58 MI patients and 52 healthy volunteers, a...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Li B,Wu Y

更新日期：2020-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Edoxaban has three dose adjustment factors (creatinine clearance, 15-50 mL/min; body weight, 60 kg or less; and concomitant medication with potent P-glycoprotein inhibitors) to prevent bleeding that results from elevated blood concentrations of the drug. A dose reduction (from 60 to 30 mg/da...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Takase T,Ikesue H,Nakagawa H,Kinoshita M,Muroi N,Kitai T,Furukawa Y,Hashida T

更新日期：2020-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The 4-factor prothrombin complex concentrate (4F-PCC) may be used to emergently achieve haemostasis in patients on anticoagulation prior to surgery. Limited data exist using the intraosseous route of administration of 4F-PCC in patients taking factor Xa inhibitors. CASE DESCRIPTION:We descr...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ratliff P,Nutley K,Schroeder W,Cottingham L

更新日期：2020-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Despite recommendations to avoid fluoroquinolones (FQs) as a first-line treatment for uncomplicated cystitis, recent data suggest that FQs remain widely prescribed. Therefore, the objectives of this study were to evaluate the appropriateness of empiric FQ use compared to nitrofurantoin for u...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Robinson TF,Barsoumian AE,Aden JK,Giancola SE

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Although the kinetic behaviour of tramadol has been described, the present study is the first to our knowledge, to report specifically on the population pharmacokinetic modelling of tramadol hydrochloride. METHODS:The parametric Iterative Two-stage Bayesian Population Model (IT2B) program foll...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Gan SH,Ismail R,Wan Adnan WA,Zulmi W,Jelliffe RW

更新日期：2004-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Diphenhydramine (DPH) is a first-generation antihistamine, which is useful in treating allergic reaction, and is usually considered innocuous. We describe a retired nurse with history of depression, who began to develop drug-seeking behaviour after her first receiving of an intramuscular (IM...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Chen TY,Yeh YW,Kuo SC,Chen CY,Lin TP,Chang CC

更新日期：2014-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Clinical use of fluconazole against fungal infections in renal transplant patients is complicated by the potentially marked and unpredictable drug-drug interactions (DDIs). We report a case of tacrolimus-fluconazole DDI in a stable renal transplant recipient and describe the mechanism, magni...

journal_title：Journal of clinical pharmacy and therapeutics

authors： He J,Yu Y,Yin C,Liu H,Zou H,Ma J,Yang W,Liu Y,Zhong L,Chen X

更新日期：2020-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Every prescriber knows that patients often do not take their medicines as prescribed. Hippocrates, the wise man of Kos, knew over two millennia ago. Our objective is to comment on the types of studies aimed at understanding and optimizing drug usage and to draw attention to the need to seek ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Li-Wan-Po A,Peterson GM

更新日期：2021-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:New first-in-class (FIC) drugs with novel mechanisms of action may be highly effective, but lack adequate safety information, and therefore may be associated with crucial post-marketing safety issues. The objective of this study was to evaluate the post-marketing risk of FIC drug with compar...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ikeda J,Kaneko M,Narukawa M

更新日期：2020-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Chronic obstructive pulmonary disease (COPD) is associated with significant morbidity and mortality, and frequent exacerbations are associated with an increased risk of death, deterioration in lung function and reduced quality of life. Current Australian guidelines developed by the Lung Foun...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Brownridge DJ,Zaidi STR

更新日期：2017-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Metronidazole is one of the drugs with a well-recognized potential to rarely cause acute pancreatitis. The relation of other drugs of the 5-aminoimidazole group (e.g. tinidazole) to acute pancreatitis remains unknown. For the treatment of protozoal infections, tinidazole may be considered as...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Hegazi MO,Saleh F,John JE

更新日期：2015-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVES:Thiopurines are cornerstone drugs in the treatment of acute lymphoblastic leukaemia (ALL), but their use can be complicated by the incidence of life-threatening leucopenia. CASE DESCRIPTION:We describe a case of a 6-year-old Chinese boy with B-ALL receiving extremely low dose of 6-mercapto...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Zhai XY,Zhou Y,Dong L,Nie AQ,Zhi LJ,Jacqz-Aigrain E,Wang TY,Wang L,Zhao W

更新日期：2021-02-01 00:00:00

abstract：:Caffeine elimination was studied in 73 patients admitted to an intensive care unit, 33 of whom had liver disease. Mean plasma clearance of caffeine in patients with no liver disease (1.30 +/- 0.79 ml/kg/min) was significantly higher than in patients with liver disease (0.39 +/- 0.23 ml/kg/min). Mean half-life of caffe...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Calatayud O,Rodríguez M,Sánchez-Alcaraz A,Ibáñez P

更新日期：1995-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are one of the preferred approved treatment options for people with type 2 diabetes (T2D) and inadequate glycaemic control. The objective of this review is to provide a general clinical overview of the similarities and differences in the ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Cornell S

更新日期：2020-09-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The complexity and diversity of irritable bowel syndrome's (IBS) presentation make treatment difficult. Although there are reviews and guidelines for treating IBS, they focus on the efficacy of medications for IBS symptoms using high-priority endpoints, leaving those of lower priority largel...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Trinkley KE,Nahata MC

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:A pain relief score 50% of the maximum is often used as a clinically meaningful outcome in meta-analyses of analgesic trials. This arbitrary value requires validation. OBJECTIVE:To determine the optimum pain relief score for predicting pain relief sufficient to obviate the need for analgesic remedication in...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Li Wan Po A,Petersen B

更新日期：2006-04-01 00:00:00

abstract：:Mean values and standard deviations are reported for theophylline plasma clearance in 45 hospitalized geriatric patients (age greater than 65 years), distributed into two groups: Group I (n = 24) included critically ill patients admitted to the ICU on total parenteral nutrition (TPN). Group II (n = 21) included patien...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Sangrador G,Sánchez-Alcaraz A,Ubeda R,Ibañez P

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Patients' own medications (POM) are medications that patients have obtained in the community setting and bring to the hospital when admitted. The practice of using POMs has not been well studied. OBJECTIVE:To identify benefits, risks and other impacts on the use of POM in hospitals. METHODS:A systematic se...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Lummis H,Sketris I,Veldhuyzen van Zanten S

更新日期：2006-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Pregabalin is used for neuropathic and postherpetic pain and generalized anxiety. The aim of this study was to obtain the onset profiles of adverse events (AE) related to falls (AEFs) such as "somnolence," "dizziness," "loss of consciousness" and "fall" onset and several clinical factor comb...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Mukai R,Hasegawa S,Umetsu R,Nakao S,Shimada K,Uranishi H,Masuta M,Suzuki H,Nishibata Y,Nakamura M

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Patients with congestive heart failure (CHF) are at risk for hyperkalemia because of coexisting comorbidities and use of multiple medications that impair potassium (K) excretion such as angiotensin converting enzyme (ACE) inhibitors. OBJECTIVE:To identify clinical factors associated with hyperkalemia on ini...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ramadan FH,Masoodi N,El-Solh AA

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:To evaluate if once-daily dose (ODD) regimens of tobramycin attain pharmacodynamic goals using individualized pharmacokinetic monitoring of critically ill patients with creatinine clearance (Clcr) over 60 mL/min. METHODS:Fifty-one adult critically ill patients treated with intravenous tobramycin with ODD wer...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Peris-Marti JF,Borras-Blasco J,Rosique-Robles JD,Gonzalez-Delgado M

更新日期：2004-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVES:Subjects of different ethnic groups may respond differently to drugs. The present study was conducted to compare the oral pharmacokinetics of midazolam among healthy volunteers from five different ethnic groups in China: Han, Mongolian, Uygur, Hui and Korean. METHODS:Healthy volunteers (10...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Guo T,Mao GF,Xia DY,Su XY,Zhao LS

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Antiviral medications cost-effectively reduce influenza-related morbidity and potentially mortality. We sought to assess the appropriateness of antiviral prescribing for influenza. METHOD:We performed a retrospective analysis of visits by adults to primary care clinics during influenza seasons...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Linder JA,Chan JC,Bates DW

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Drug-drug interaction is a potential cause of adverse drug reactions. The incidence of such drug interactions in university hospitals in Thailand is unknown. PURPOSE:To estimate the rate of potential drug-drug interactions in outpatients of a typical Thai university hospital, and to identify risk factors fo...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Janchawee B,Wongpoowarak W,Owatranporn T,Chongsuvivatwong V

更新日期：2005-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The CHOP regimen with rituximab (R-CHOP) remains the standard for chemotherapy in patients with aggressive non-Hodgkin's lymphoma (NHL). The cardiotoxicity of doxorubicin appears to be a key problem in clinical practice. We studied the cardiotoxicity of CHOP/R-CHOP regimen in a retrospective...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Limat S,Daguindau E,Cahn JY,Nerich V,Brion A,Perrin S,Woronoff-Lemsi MC,Deconinck E

更新日期：2014-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Low-dose methotrexate (LDMTX) has been widely used for many decades in clinical settings, with good safety profiles compared with those of high-dose methotrexate. LDMTX is also used as one of the off-label conservative therapies in treating placenta accreta (PA). Until now, only a few mild a...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tan Z,Liu W,Guo H,Hu K,Zhao R

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The use of extemporaneously prepared admixtures of drugs must be supported by documentation of their chemical stability. OBJECTIVE:To assess the physical compatibility and the chemical stability of nefopam hydrochloride, a centrally acting non-opioid analgesic, when admixed with selected proton pump inhibit...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kambia NK,Luyckx M,Dine T,Dupin-Spriet T,Gressier B,Brunet C

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In our original study based on five monozygotic twin pairs and seven same-sex sib pairs, we previously showed that genetic factors contribute to body weight gain induced by the atypical antipsychotic clozapine. We aim to study this further by including patients treated with the atypical antipsy...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Gebhardt S,Theisen FM,Haberhausen M,Heinzel-Gutenbrunner M,Wehmeier PM,Krieg JC,Kühnau W,Schmidtke J,Remschmidt H,Hebebrand J

更新日期：2010-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Based on extrapolation, biosimilar infliximab (IFX) was approved to treat inflammatory bowel disease (IBD). The first studies in adults have shown similar efficacy and safety in comparison with reference drug. The aim of this review was to collect and evaluate all the literature data regardi...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Dipasquale V,Romano C

更新日期：2020-12-01 00:00:00