KAI1, CAR, and Smad4 expression in the progression of colorectal tumor.

abstract：:Soft drinks containing dietary fiber are popular in Japan. There seem to be two types, one containing polydextrose and the other, oligosaccharide. These beverages are claimed to be useful for constipation or obesity, but data are scanty. We examined four such fiber-containing beverages [Fibe-mini Otsuka Pharmaceutical...

journal_title：Journal of gastroenterology

authors： Kondo T,Nakae Y

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Although previous studies have indicated that serum pepsinogen I levels, as well as the pepsinogen I/II ratio, were positively correlated with maximal gastric output, the relationship may be different between Helicobacter pylori-negative and -positive subjects. The aim of this study was to investigate the re...

journal_title：Journal of gastroenterology

authors： Iijima K,Sekine H,Koike T,Imatani A,Ohara S,Shimosegawa T

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:The purpose of our study was to evaluate the long-term outcome and complications of balloon-occluded retrograde transvenous obliteration (B-RTO) in patients with hemorrhage from gastric fundal varices. METHODS:Thirty-four consecutive patients with bleeding from gastric varices who were treated with B-RTO we...

journal_title：Journal of gastroenterology

authors： Hiraga N,Aikata H,Takaki S,Kodama H,Shirakawa H,Imamura M,Kawakami Y,Takahashi S,Toyota N,Ito K,Tanaka S,Kitamoto M,Chayama K

更新日期：2007-08-01 00:00:00

abstract：:From its pattern of metastasis and recurrence, gastric carcinoma can be recognized as a slow-growing malignancy whose local control is still the most important part of treatment. With application of asymptomatic population screening and awareness of the high risk of this disease among the general population in Japan, ...

journal_title：Journal of gastroenterology

authors： Sasako M

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:Autoimmune pancreatitis (AIP) is a unique form of pancreatitis and can be complicated with various extrapancreatic lesions. Little is known about the long-term clinical course of AIP. Here we aimed to document the clinical course of AIP. METHODS:For this study, we recruited 21 patients, averaging 66.5 years in...

journal_title：Journal of gastroenterology

authors： Uchida K,Yazumi S,Nishio A,Kusuda T,Koyabu M,Fukata M,Miyoshi H,Sakaguchi Y,Fukui T,Matsushita M,Takaoka M,Okazaki K

更新日期：2009-01-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) could be curable by "immune rest" and correction of the genetic predisposition inherent in allogeneic hematopoietic stem cell transplantation. However, balancing risks against benefits remains challenging. The application of mesenchymal stem cells (MSCs) serving as a site-regulated "dr...

journal_title：Journal of gastroenterology

authors： Nagaishi K,Arimura Y,Fujimiya M

更新日期：2015-03-01 00:00:00

abstract：:Our objective was to determine whether the prevalence of vacuolating cytotoxin production differed among Helicobacter pylori isolates obtained from patients with chronic gastritis, gastric ulcer, or duodenal ulcer. We examined the vacuolating cytotoxin production of 114 clinical H. pylori isolates in rabbit gastic epi...

journal_title：Journal of gastroenterology

authors： Kodama K,Fujioka T,Ito A,Kubota T,Murakami K,Nasu M

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:In Japan, generally, patients with chronic hepatitis C are aged. The aim of this study was to investigate the effect of interferon (IFN) therapy on the mortality of chronic hepatitis C patients over age 60. METHODS:Seven-hundred and seven patients with histologically proven chronic hepatitis C were enrolled...

journal_title：Journal of gastroenterology

authors： Imai Y,Kasahara A,Tanaka H,Okanoue T,Hiramatsu N,Tsubouchi H,Yoshioka K,Kawata S,Tanaka E,Hino K,Hayashi K,Tamura S,Itoh Y,Sasaki Y,Kiyosawa K,Kakumu S,Okita K,Hayashi N

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Peristaltic reflex does not fully explain the polarity of peristalsis. In the distal colon, we propose that the balance of circular muscle contraction proximal and distal to the pellet is a local reflex that predicts polarity of peristalsis. METHODS:Guinea pig distal colon segments were harvested, and fecal...

journal_title：Journal of gastroenterology

authors： Gribovskaja-Rupp I,Kwak JM,Takahashi T,Ludwig K

更新日期：2014-05-01 00:00:00

abstract：:Accumulating data from animal models indicate that Inflammatory bowel disease (IBD) is mediated by a much more complicated mechanism than previously predicted. For example, the role of an individual molecule in the pathogenesis of IBD distinctly differs depending on several factors, including the fundamental mechanism...

journal_title：Journal of gastroenterology

authors： Mizoguchi A,Mizoguchi E

更新日期：2008-01-01 00:00:00

abstract：:In 1992, a seroepidemiologic study was carried out among hemodialysis patients and the general population in Fukuoka and Okinawa, Japan to determine the presence of hepatitis C virus (HCV) infection and HCV viremia. The markers used were antibody to HCV, determined by second-generation assay (anti-HCV), and HCV RNA, d...

journal_title：Journal of gastroenterology

authors： Hayashi J,Yoshimura E,Nabeshima A,Kishihara Y,Ikematsu H,Hirata M,Maeda Y,Kashiwagi S

更新日期：1994-06-01 00:00:00

abstract：:We measured urokinase-type plasminogen activator (u-PA) plasma levels in patients with various chronic liver diseases, including hepatocellular carcinoma (HCC), also measuring these levels in healthy volunteers. Plasma u-PA levels in the group of patients with decompensated liver cirrhosis (mean modified Pugh score of...

journal_title：Journal of gastroenterology

authors： Sato S,Higashi T,Ouguchi S,Hino N,Tsuji T

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Few epidemiologic studies have examined the role of nutrient intake in the development of pancreatic cancer in Japan. We addressed this association in a population-based case-control study. METHODS:The cases were 109 patients who were newly diagnosed with pancreatic cancer between January 2000 and March 200...

journal_title：Journal of gastroenterology

authors： Lin Y,Tamakoshi A,Hayakawa T,Naruse S,Kitagawa M,Ohno Y

更新日期：2005-03-01 00:00:00

abstract：:One complication of choledochal cyst in adulthood is the development of secondary carcinoma, usually well-differentiated adenocarcinoma. We report a case of extrahepatic bile duct carcinoma associated with choledochal cyst and presenting predominantly sarcomatous features. The patient was a 52-year-old female who pres...

journal_title：Journal of gastroenterology

authors： Nonomura A,Mizukami Y,Matsubara F,Ueda H

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:The relative contribution of gastric acid secretion and Helicobacter pylori infection to low-dose aspirin-induced gastropathy remains to be clarified. This is partly because the capability of the infection to modify gastric acid secretion complicates the interaction. The aim of this study was to estimate the...

journal_title：Journal of gastroenterology

authors： Iijima K,Ara N,Abe Y,Koike T,Iwai W,Uno K,Asano N,Imatani A,Ohara S,Shimosegawa T

更新日期：2011-05-01 00:00:00

abstract：:The clinical significance of small intestinal damage caused by nonsteroidal anti-inflammatory drugs (NSAIDs) remains under-appreciated. It occurs with greater frequency than the damage caused by these drugs in the upper gastrointestinal tract, but is much more difficult to diagnose and treat. Although the pathogenesis...

journal_title：Journal of gastroenterology

authors： Syer SD,Blackler RW,Martin R,de Palma G,Rossi L,Verdu E,Bercik P,Surette MG,Aucouturier A,Langella P,Wallace JL

更新日期：2015-04-01 00:00:00

abstract：:To study the appropriate period for formalin fixation in order to detect p53 abnormalities in formalin-fixed tissue, we used seven surgically resected human colorectal cancer specimens. The immunohistochemical reactivity of p53 immunostaining and amplification of DNA by polymerase chain reaction (PCR) of the p53 gene ...

journal_title：Journal of gastroenterology

authors： Matsubayashi H,Watanabe H,Nishikura K,Ajioka Y,Maejima T,Kijima H,Saitoh T

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Little is known about the difference in enhancement patterns of hepatocellular carcinoma (HCC) during multistep hepatocarcinogenesis between the post-vascular phase of Sonazoid-enhanced ultrasonography (SEUS) and hepatobiliary phase of gadolinium ethoxybenzyl diethylenetriamine (Gd-EOB-DTPA)-enhanced MRI, as...

journal_title：Journal of gastroenterology

authors： Ohama H,Imai Y,Nakashima O,Kogita S,Takamura M,Hori M,Seki Y,Sawai Y,Igura T,Fukuda K,Makino Y,Morimoto O,Ohsawa M,Sakamoto M,Murakami T

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Ghrelin is a novel 28-amino-acid peptide isolated from rat and human stomach. This peptide is an endogenous ligand for the growth hormone secretagogue receptor and stimulates the release of growth hormones. Although the principal site of ghrelin synthesis has been reported to be in the stomach, there have be...

journal_title：Journal of gastroenterology

authors： Tanaka-Shintani M,Watanabe M

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:NADPH oxidase 1 (Nox1) is preferentially expressed in the colon, but its functional role is not fully understood. This study was designed to elucidate a potential role of Nox1 in inflammation of the colon. METHODS:Superoxide production by T84 cells was measured by the cytochrome c method. Protein and mRNA l...

journal_title：Journal of gastroenterology

authors： Kamizato M,Nishida K,Masuda K,Takeo K,Yamamoto Y,Kawai T,Teshima-Kondo S,Tanahashi T,Rokutan K

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Dual oral therapy with daclatasvir plus asunaprevir yielded an SVR rate of 85% among patients with genotype 1b HCV. Treatment failure mainly occurred in patients with pre-existing HCV with NS5A-Y93H mutation. The significance of the mutation was evaluated. METHODS:The percent of serum NS5A-Y93H strains rela...

journal_title：Journal of gastroenterology

authors： Uchida Y,Kouyama J,Naiki K,Sugawara K,Ando S,Nakao M,Motoya D,Inao M,Imai Y,Nakayama N,Mochida S

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Anemia of inflammation, commonly observed in patients with chronic diseases, is associated with decreased serum iron. Hepcidin, mainly produced by hepatocytes in a STAT3- and/or SMAD-dependent manner, is involved in iron homeostasis. What remains to be established is whether or not the hepatic IL-6/STAT3 sig...

journal_title：Journal of gastroenterology

authors： Sakamori R,Takehara T,Tatsumi T,Shigekawa M,Hikita H,Hiramatsu N,Kanto T,Hayashi N

更新日期：2010-02-01 00:00:00

abstract：:There have been numerous reports that mucinous cystadenoma of the pancreas can transform to mucinous cystadenocarcinoma after cystenterostomy, but few authors have reported morphological changes long after cystenterostomy for mucinous cystadenoma. A 41-year-old Japanese woman had undergone cystgastrostomy at a nearby ...

journal_title：Journal of gastroenterology

authors： Masatsugu T,Yamaguchi K,Arima T,Chijiiwa K,Tanaka M

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Insufflation with carbon dioxide (CO(2)) in colonoscopy has not been widely adopted and, consequently, limited data are available on insufflated gas volume and blood pCO(2). The aim of this study was to compare CO(2) and air as an insufflation agent in patients undergoing colonoscopy without sedation in term...

journal_title：Journal of gastroenterology

authors： Yamano HO,Yoshikawa K,Kimura T,Yamamoto E,Harada E,Kudou T,Katou R,Hayashi Y,Satou K

更新日期：2010-12-01 00:00:00

abstract：:We report a case of gastrojejunal fistula caused by benign gastric ulcer, a very rare condition. The patient was an 81-year-old-woman who had had multiple recurrences of gastric ulcer. She also had diabetes mellitus. She was admitted to our hospital because of a left femoral head fracture, necessitating a mechanical b...

journal_title：Journal of gastroenterology

authors： Matsuoka M,Yoshida Y,Hayakawa K,Fukuchi S

更新日期：1998-04-01 00:00:00

abstract：:To assess the efficacy of the zinostatin derivative, the anti-tumor agent, styrene-maleic acid neocarzinostatin, in treating multiple small liver cancers, 29 patients with multiple hepatocellular carcinoma of 3 cm or less in diameter were treated with intraarterial injections of this high molecular weight agent, mixed...

journal_title：Journal of gastroenterology

authors： Ikeda K,Saitoh S,Suzuki Y,Tsubota A,Koida I,Kobayashi M,Arase Y,Chayama K,Murashima N,Kumada H

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Loss of imprinting (LOI) of the insulin-like growth factor 2 (IGF2) is an early event in the development of colorectal cancer (CRC). Whether LOI of IGF2 denotes a molecular or clinical cancer subgroup is currently unknown. METHODS:Tumor biopsies and paired normal mucosa from 399 patients with extensive clin...

journal_title：Journal of gastroenterology

authors： Belharazem D,Magdeburg J,Berton AK,Beissbarth L,Sauer C,Sticht C,Marx A,Hofheinz R,Post S,Kienle P,Ströbel P

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:The apelin receptor (APJ) is related to angiotensin-like-receptor 1 (AGTRL1). This study was designed to elucidate the in vivo localization and changes of APJ in cirrhotic liver, and the in vitro changes of APJ expression in cultured hepatic stellate cells (HSCs) and capillarized sinusoidal endothelial cells...

journal_title：Journal of gastroenterology

authors： Yokomori H,Oda M,Yoshimura K,Machida S,Kaneko F,Hibi T

更新日期：2011-02-01 00:00:00

abstract：:Cowden's disease, multiple hamartoma syndrome, is a dominantly inherited disorder characterized by multiple hamartomas of ectodermal, endodermal, and mesodermal origin and also by a high incidence of malignant tumors. Despite many efforts to identify the genetic alterations responsible for the syndrome, the molecular ...

journal_title：Journal of gastroenterology

authors： Suzuki T,Ichinose M,Matsubara Y,Yahagi N,Kurokawa K,Fukamachi H,Miki K

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Gastric marker mucins (MUC5AC and MUC6) and intestinal marker molecules (MUC2 and CD10) have been used to determine the cell lineage of epithelial cell of gastric carcinoma (GC). METHODS:To clarify the characteristics of Epstein-Barr virus (EBV)-associated GC, 18 cases were immunohistochemically evaluated a...

journal_title：Journal of gastroenterology

authors： Barua RR,Uozaki H,Chong JM,Ushiku T,Hino R,Chang MS,Nagai H,Fukayama M

更新日期：2006-08-01 00:00:00