Carbon dioxide insufflation for colonoscopy: evaluation of gas volume, abdominal pain, examination time and transcutaneous partial CO2 pressure.

Abstract:

BACKGROUND:Insufflation with carbon dioxide (CO(2)) in colonoscopy has not been widely adopted and, consequently, limited data are available on insufflated gas volume and blood pCO(2). The aim of this study was to compare CO(2) and air as an insufflation agent in patients undergoing colonoscopy without sedation in terms of insufflated gas volume, pCO(2), pain and examination time. METHODS:This was a randomized, double-blind, control trial. Consecutive patients presenting for colonoscopy, excluding those with lung or malignant disease, were randomized into two groups: insufflation with air or with CO(2), respectively. Insufflated gas volume, pain, pCO(2) and examination time were assessed. RESULTS:The study cohort comprised 120 patients (66 randomized to CO(2) group). No significant difference in insufflated gas volumes was found between the CO(2) and air groups. The mean pCO(2) measured before, during (the peak value) and 30 min after colonoscopy were 40, 43 and 40 mmHg, respectively, in both groups. The pain scores in the air group were significantly greater than those in the CO(2) group until 3 h after the examination. There was a significant faster cecal intubation time and a trend toward shorter examination time in the CO(2) group. CONCLUSIONS:The CO(2) gas volume used in our study (14.0 L) was much greater than that reported by others (8.3 L), but the pCO(2) values were still within the normal reference range, indicating the safety of CO(2) insufflation over a greater range of CO(2) gas volume. Among our patients, CO(2) insufflation was associated with relatively less pain and a shorter examination time. Based on our results, we recommend that CO(2) become the standard gas for insufflation in patients undergoing colonoscopy without sedation.

journal_name

J Gastroenterol

authors

Yamano HO,Yoshikawa K,Kimura T,Yamamoto E,Harada E,Kudou T,Katou R,Hayashi Y,Satou K

doi

10.1007/s00535-010-0286-5

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

1235-40

issue

12

eissn

0944-1174

issn

1435-5922

journal_volume

45

pub_type

杂志文章,随机对照试验
  • Colonic cancer in a patient with primary sclerosing cholangitis and long-standing ulcerative colitis.

    abstract::A 27-year-old woman with a 9-year history of ulcerative colitis involving the entire colon was admitted to our hospital in August 1992 because of bloody stools and left lower abdominal pain. She had been treated with sulfasalazine since 1983 and the colitis had been clinically quiescent or mild for 7 years. She had al...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/BF01213301

    authors: Seo M,Okada M,Osamura S,Hara S,Umeno T,Maeshiro K,Yamada Y,Yuh K

    更新日期:1997-02-01 00:00:00

  • Long-term follow-up study of Crohn's disease in Japan. The Research Committee of Inflammatory Bowel Disease in Japan.

    abstract::Two hundred and three patients with Crohn's disease seen at Kyushu University, Fukuoka University, and their affiliated centers from 1973 to 1988 were followed for 4.4 +/- 3.2 years (mean +/- SD), to evaluate the prognosis relative to life span and surgery. Cumulative survival rate and cumulative operation rate were c...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Iida M,Yao T,Okada M

    更新日期:1995-11-01 00:00:00

  • The role of nuclear factor-kappaB in the effect of angiotensin II in the paraventricular nucleus in protecting the gastric mucosa from ischemia-reperfusion injury in rats.

    abstract:BACKGROUND:The purpose of this study was to elucidate the role of nuclear factor kappaB (NF-kappaB) in the development of gastric ischemia-reperfusion (GI-R) injury and in mediating the effects of angiotensin II (Ang II) in the paraventricular nucleus (PVN) on GI-R injury. METHODS:GI-R injury was induced in rats by cl...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-008-2217-2

    authors: Zhang YM,Wei EQ,Hu X,Qiao WL,Shi Y,Xu M,Zhang JF

    更新日期:2008-01-01 00:00:00

  • Introduction of an examination and treatment for Helicobacter pylori infection in high school health screening.

    abstract:BACKGROUND:Recently, a significant relationship between gastric cancer and Helicobacter pylori infection has been proven. The purpose of this study was to elucidate the actual conditions of H. pylori infection in Japanese teenagers. METHODS:The study subjects were students at a certain high school between 2007 and 200...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-011-0450-6

    authors: Akamatsu T,Ichikawa S,Okudaira S,Yokosawa S,Iwaya Y,Suga T,Ota H,Tanaka E

    更新日期:2011-12-01 00:00:00

  • Dieulafoy's vascular malformation of the jejunum: first case report of laparoscopic treatment.

    abstract::A case of Dieulafoy's vascular malformation of the jejunum treated by laparoscopic surgery is described. The patient was a 31-year-old-woman who had complained of melena and had severe anemia needing blood transfusion. Angiography revealed microaneurysms and hypervascularity of the jejunum in the area between the firs...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1007/s00535-003-1305-6

    authors: Mino A,Ogawa Y,Ishikawa T,Uchima Y,Yamazaki M,Nakamura S,Yukawa T,Matsumoto T,Arakawa T,Hirakawa K

    更新日期:2004-01-01 00:00:00

  • The tight junction of pancreatic exocrine cells is a morphometrically dynamic structure altered by intraductal hypertension.

    abstract::The tight junction of pancreatic exocrine cells is thought to regulate paracellular permeability, and is a possible reflux route of pancreatic juice into the blood flow. Morphological changes in the tight junction of canine pancreatic acinar cells following intraductal hypertension and secretin stimulation were morpho...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350070035

    authors: Akao S,Oya M,Akiyama H,Ishikawa H

    更新日期:2000-01-01 00:00:00

  • Characteristics of Japanese inflammatory bowel disease susceptibility loci.

    abstract:BACKGROUND:There are substantial differences in inflammatory bowel disease (IBD) genetics depending on the populations examined. We aimed to identify Japanese population-specific or true culprit susceptibility genes through a meta-analysis of past genetic studies of Japanese IBD. METHODS:For this study, we reviewed 2,...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00535-013-0866-2

    authors: Arimura Y,Isshiki H,Onodera K,Nagaishi K,Yamashita K,Sonoda T,Matsumoto T,Takahashi A,Takazoe M,Yamazaki K,Kubo M,Fujimiya M,Imai K,Shinomura Y

    更新日期:2014-08-01 00:00:00

  • Meta-analysis: mortality and serious adverse events of peginterferon plus ribavirin therapy for chronic hepatitis C.

    abstract:BACKGROUND:Pegylated interferon (PEG-IFN) plus ribavirin (RBV) therapy is the current standard of care for patients with chronic hepatitis C. Determining precisely the risk of serious adverse events (SAEs) and mortality from a single study is rather difficult because of the infrequency of such events. The aim of this s...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.1007/s00535-012-0631-y

    authors: Minami T,Kishikawa T,Sato M,Tateishi R,Yoshida H,Koike K

    更新日期:2013-02-01 00:00:00

  • Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancers.

    abstract::Chronic inflammatory bowel disease (IBD) is an important etiologic factor in the development of colorectal cancer. However, the mechanism underlying the development of colorectal cancers through chronic inflammation is not known. Activation-induced cytidine deaminase (AID) was originally identified as an inducer of so...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-010-0326-1

    authors: Endo Y,Marusawa H,Chiba T

    更新日期:2011-01-01 00:00:00

  • Comparison of long-term outcomes after endoscopic sphincterotomy versus endoscopic papillary balloon dilation: a propensity score-based cohort analysis.

    abstract:BACKGROUND:Endoscopic sphincterotomy (ES) is widely performed in patients with common bile duct stones (CBDS). However, the long-term outcomes of patients following ES have not been sufficiently elucidated. Impaired papillary function following ES may result in additional late complications. In contrast, endoscopic pap...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-012-0707-8

    authors: Doi S,Yasuda I,Mukai T,Iwashita T,Uemura S,Yamauchi T,Nakashima M,Adachi S,Shimizu M,Tomita E,Itoi T,Moriwaki H

    更新日期:2013-09-01 00:00:00

  • Paired tumor marker of soluble E-selectin and its ligand sialyl Lewis A in colorectal cancer.

    abstract:BACKGROUND:Better diagnosis of metastatic disease has been pursued by oncologists: however, many of the tumor markers have been still controversial. Our purpose was to estimate the usefulness of soluble E-selectin and its ligand sialyl Lewis A for more accurate diagnosis as a combined tumor marker for metastases in col...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350170004

    authors: Ito K,Ye CL,Hibi K,Mitsuoka C,Kannagi R,Hidemura K,Ando H,Kasai Y,Akiyama S,Nakao A

    更新日期:2001-12-01 00:00:00

  • Hepatic subcapsular hematoma after extracorporeal shock wave lithotripsy (ESWL) for pancreatic stones.

    abstract::We present a patient with complication of huge hepatic subcapsular hematoma after extracorporeal shock wave lithotripsy (ESWL) for pancreatic lithotripsy. The hematoma measured 78-110mm. Angiography showed a subcapsular hematoma, rather than a hematoma in the liver. In the arterial phase, the distal end of the small v...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350050325

    authors: Hirata N,Kushida Y,Ohguri T,Wakasugi S,Kojima T,Fujita R

    更新日期:1999-12-01 00:00:00

  • Does gastroesophageal reflux have an influence on bleeding from esophageal varices?

    abstract:BACKGROUND:Mucosal breaks induced by gastroesophageal reflux of gastric contents were more frequently found on the right anterior wall of the lower esophagus. Bleeding from esophageal varices may be also derived from gastroesophageal reflux. The circumferential location of the ruptured esophageal varices was evaluated ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-008-2232-3

    authors: Okamoto E,Amano Y,Fukuhara H,Furuta K,Miyake T,Sato S,Ishihara S,Kinoshita Y

    更新日期:2008-01-01 00:00:00

  • Regulation of anergy-related ubiquitin E3 ligase, GRAIL, in murine models of colitis and patients with Crohn's disease.

    abstract:BACKGROUND:Abrogating tolerance is a critical step in the pathogenesis of Crohn's disease (CD). T cell-anergy is one of the main mechanisms of tolerance and is regulated by the gene related to anergy in lymphocytes (GRAIL). This study investigated the expressions and regulation of GRAIL in CD and murine colitis models....

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-013-0923-x

    authors: Mukai A,Iijima H,Hiyama S,Fujii H,Shinzaki S,Inoue T,Shiraishi E,Kawai S,Araki M,Hayashi Y,Kondo J,Mizushima T,Kanto T,Egawa S,Nishida T,Tsujii M,Takehara T

    更新日期:2014-12-01 00:00:00

  • Effects of epidermal growth factor and insulin on migration and proliferation of primary cultured rabbit gastric epithelial cells.

    abstract::We assessed the influence of epidermal growth factor (EGF) and insulin on gastric epithelial restoration in vitro. Rabbit gastric epithelial cells were cultured and formed a complete monolayer cell sheet in 2 days. We created a wound (1.8 +/- 0.05 mm2) by denuding an area of cells, and EGF (0.1-30 ng/ml) and/or insuli...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/BF02934104

    authors: Maehiro K,Watanabe S,Hirose M,Iwazaki R,Miwa H,Sato N

    更新日期:1997-10-01 00:00:00

  • Cellular membrane fluidity measurement by fluorescence polarization in indomethacin-induced gastric cellular injury in vitro.

    abstract:BACKGROUND:Gastric complications of indomethacin involve generation of reactive oxygen species, which induce gastric mucosal injury via lipid peroxidation of cell membranes. Peroxidation by reactive oxygen species alters the amounts of unsaturated fatty acids in the cell membrane and thus affects membrane fluidity. Ind...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-007-2116-y

    authors: Kaneko T,Matsui H,Shimokawa O,Nakahara A,Hyodo I

    更新日期:2007-12-01 00:00:00

  • Symptomatic and endoscopic outcome of heartburn 3-4.5 years after starting lansoprazole therapy: a prospective study of 142 patients.

    abstract:BACKGROUND:Heartburn is a common symptom with great impact on quality of life and on the economy. An approach that helps to alleviate patients' symptoms, decrease the burden on the economy, and improve longterm outcome is needed. Step-down therapy, starting with the proton pump inhibitor lansoprazole, seems to achieve ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-003-1194-8

    authors: Abu Farsakh N

    更新日期:2003-01-01 00:00:00

  • Percutaneous ultrasound-guided radiofrequency ablation of hepatocellular carcinoma with artificially induced pleural effusion and ascites.

    abstract:BACKGROUND:Ultrasound-guided procedures are sometimes of limited use because the tumor is located under the diaphragm or near the surface of the liver. We investigated the safety and efficacy of radiofrequency ablation (RFA) with artificial pleural effusion and/or artificial ascites. METHODS:Between January 2002 and M...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-006-1949-0

    authors: Uehara T,Hirooka M,Ishida K,Hiraoka A,Kumagi T,Kisaka Y,Hiasa Y,Onji M

    更新日期:2007-04-01 00:00:00

  • Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44⁺ gastric cancer cells via attenuating Wnt signaling.

    abstract:BACKGROUND:Gastric cancer stem cells (CSCs), which require activation of Wnt signaling to maintain their self-renewal and tumorigenicity, are proposed to be critical targets for effective therapy of gastric carcinomas. Gene therapies that are delivered by adenovirus of serotype 5 (Ad5) or chimeric 5/35(Ad5/35) adenovir...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-012-0711-z

    authors: Wang B,Liu J,Ma LN,Xiao HL,Wang YZ,Li Y,Wang Z,Fan L,Lan C,Yang M,Hu L,Wei Y,Bian XW,Chen D,Wang J

    更新日期:2013-07-01 00:00:00

  • Quantification of Helicobacter pylori infection: Simple and rapid 13C-urea breath test in Taiwan.

    abstract::The 13C-urea breath test (13C-UBT) is a non-invasive method for detecting Helicobacter pylori. This study was performed to determine the cutoff value and evaluate the sensitivity and specificity of 13C-UBT in Taiwan. 13C-Urea (100 mg of 99% 13C-labeled urea) was dissolved in 50 ml sterile water for the test. The test ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350050092

    authors: Wang WM,Lee SC,Ding HJ,Jan CM,Chen LT,Wu DC,Liu CS,Peng CF,Chen YW,Huang YF,Chen CY

    更新日期:1998-06-01 00:00:00

  • Long-term prognosis of patients with hepatitis B infection: causes of death and utility of nucleos(t)ide analogue therapy.

    abstract:BACKGROUND:Long-term nucleos(t)ide analogue (NA) therapy for chronic hepatitis B (CHB) patients has been reported to reduce the risk of hepatocellular carcinoma (HCC) development. However, survival rates and causes of death in CHB patients either treated or not treated with NA therapy are unclear. Therefore, we investi...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-014-1011-6

    authors: Tada T,Kumada T,Toyoda H,Kiriyama S,Tanikawa M,Hisanaga Y,Kanamori A,Kitabtake S,Ito T

    更新日期:2015-07-01 00:00:00

  • Meta-analysis: the effect of interferon on development of hepatocellular carcinoma in patients with chronic hepatitis B virus infection.

    abstract:PURPOSE:In patients chronically infected with hepatitis B virus, interferon has been used for the purpose of viral suppression by loss of hepatitis B e antigen (HBeAg) with or without seroconversion to antibody to HBeAg (anti-HBe). However, discussion about the effect of interferon on the development of hepatocellular ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.1007/s00535-009-0024-z

    authors: Miyake Y,Kobashi H,Yamamoto K

    更新日期:2009-01-01 00:00:00

  • Hybrid training of voluntary and electrical muscle contractions reduces steatosis, insulin resistance, and IL-6 levels in patients with NAFLD: a pilot study.

    abstract:BACKGROUND:Physical inactivity is a risk factor for the development of non-alcoholic fatty liver disease (NAFLD). "Hybrid training", a training that involves both voluntary and electrical muscle contractions, causes beneficial alterations in muscles even after short durations of exercise. The aim of this study was to i...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-011-0378-x

    authors: Kawaguchi T,Shiba N,Maeda T,Matsugaki T,Takano Y,Itou M,Sakata M,Taniguchi E,Nagata K,Sata M

    更新日期:2011-06-01 00:00:00

  • Eradication of Helicobacter pylori for primary gastric cancer and secondary gastric cancer after endoscopic mucosal resection.

    abstract::Because most gastric cancers develop from a background of Helicobacter pylori-infected gastric mucosa, H. pylori plays an important role in gastric carcinogenesis. Therefore, eradication of H. pylori may inhibit the incidence of gastric cancers. In experimental studies, H. pylori eradication has proved to act as a pro...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1007/s00535-006-1928-5

    authors: Kato M,Asaka M,Ono S,Nakagawa M,Nakagawa S,Shimizu Y,Chuma M,Kawakami H,Komatsu Y,Hige S,Takeda H

    更新日期:2007-01-01 00:00:00

  • Anorectal malignant melanoma: preoperative usefulness of magnetic resonance imaging.

    abstract::Magnetic resonance imaging (MRI) findings in three patients with primary anorectal malignant melanoma are described. Two patients had melanotic and one had amelanotic anorectal melanoma. The findings of MRI with a pelvic coil and an endorectal coil were consistent with pathologic findings. MRI with a pelvic coil demon...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-005-1638-4

    authors: Matsuoka H,Nakamura A,Iwamoto K,Sugiyama M,Hachiya J,Atomi Y,Masaki T

    更新日期:2005-08-01 00:00:00

  • Long-term effects of Helicobacter pylori eradication in Mongolian gerbils.

    abstract:BACKGROUND:In this study, to clarify whether Helicobacter pylori eradication alters the course of the development of gastric mucosal changes in the stomach, we examined the long-term effects of H. pylori eradication on H. pylori-inoculated gerbils. METHODS:A total of 40 H. pylori-inoculated gerbils were randomized and...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350200130

    authors: Hirayama F,Takagi S,Yokoyama Y,Yamamoto K,Iwao E,Haga K

    更新日期:2002-01-01 00:00:00

  • Advantages of immunostaining over DNA analysis using PCR amplification to detect p53 abnormality in long-term formalin-fixed tissues of human colorectal carcinomas.

    abstract::To study the appropriate period for formalin fixation in order to detect p53 abnormalities in formalin-fixed tissue, we used seven surgically resected human colorectal cancer specimens. The immunohistochemical reactivity of p53 immunostaining and amplification of DNA by polymerase chain reaction (PCR) of the p53 gene ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350050153

    authors: Matsubayashi H,Watanabe H,Nishikura K,Ajioka Y,Maejima T,Kijima H,Saitoh T

    更新日期:1998-10-01 00:00:00

  • Isolation of novel mouse genes that were differentially expressed in W/W(V) mouse fundus.

    abstract:BACKGROUND:Using cDNA microarray analysis that displays a total of 8734 mouse genes, we have identified 21 known and novel transcripts, including mouse expressed sequence tags (ESTs) that were consistently up- or downregulated in the fundus of wild-type mice and W/W(V) mice, where intramuscular interstitial cells of Ca...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-003-1283-8

    authors: Daigo Y,Takayama I,Ward SM,Sanders KM,Fujino MA

    更新日期:2004-01-01 00:00:00

  • Photodynamic therapy for human hepatoma-cell-line tumors utilizing biliary excretion properties of indocyanine green.

    abstract:BACKGROUND:Photodynamic therapy (PDT) has not been reported for human hepatoma, because cancer cells only weakly take up the photosensitizer. Indocyanine green (ICG) is a photosensitizer normally excreted into the bile, and bile excretion is impaired in human hepatomas. We examined whether human hepatoma cell lines pre...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-013-0775-4

    authors: Kaneko J,Inagaki Y,Ishizawa T,Gao J,Tang W,Aoki T,Sakamoto Y,Hasegawa K,Sugawara Y,Kokudo N

    更新日期:2014-01-01 00:00:00

  • D-Penicillamine improved laparoscopic and histological findings of the liver in a patient with Wilson's disease: 3-year follow-up after diagnosis of Coombs-negative hemolytic anemia of Wilson's disease.

    abstract::We report a 13-year-old girl who presented with hepatic failure and hemolytic anemia. Laboratory findings showed a normal serum copper level (104 microg/dl), high urinary copper level (2370 microg/dl), and low serum ceruloplasmin level (14.3 microg/dl). Slit-lamp examination revealed Kayser-Fleischer rings on her corn...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-005-1600-5

    authors: Sakaida I,Kawaguchi K,Kimura T,Tamura F,Okita K

    更新日期:2005-06-01 00:00:00