Cellular membrane fluidity measurement by fluorescence polarization in indomethacin-induced gastric cellular injury in vitro.

abstract：:Preoperative biliary drainage (PBD) has been thought to be preferable regardless of the site of biliary strictures, e.g., distal or proximal strictures because PBD by endoscopy or interventional radiology decreases postoperative mortality and morbidity rates. However, recently, several studies have revealed that PBD s...

journal_title：Journal of gastroenterology

authors： Umeda J,Itoi T

更新日期：2015-09-01 00:00:00

abstract：:Gastrointestinal symptoms such as abdominal pain, dyspepsia, and diarrhea are relatively nonspecific and a common cause for seeking medical attention. To date, it is challenging for physicians to differentiate between functional and organic gastrointestinal conditions and it involves the use of serological and endosco...

journal_title：Journal of gastroenterology

authors： Ikhtaire S,Shajib MS,Reinisch W,Khan WI

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Among the factors influencing variceal relapse after endoscopic treatment, portal hemodynamic changes, especially in portal systemic shunts, could be the most important factor because hemodynamics are directly related to the development of esophageal varices. We aimed to clarify the influence of endoscopic t...

journal_title：Journal of gastroenterology

authors： Ito K,Matsutani S,Maruyama H,Akiike T,Nomoto H,Suzuki T,Fukuzawa T,Mizumoto H,Saisho H

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Ulcerative colitis (UC) is characterized by chronic inflammation in the colon and epigenetic factors underlying the occurrence. Circular RNAs (circRNAs) have been under intensive focus due to the circular construct and gene-regulating functions. However, the changes and roles of circRNAs in UC remain unknown...

journal_title：Journal of gastroenterology

authors： Wang T,Chen N,Ren W,Liu F,Gao F,Ye L,Han Y,Zhang Y,Liu Y

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:The gap junction (GJ) plays important roles in the maintenance of tissue homeostasis, the control of cell growth and differentiation, and the prevention of experimental hepatocarcinogenesis. In this study, we examined the relationship between the expression of the GJ protein connexin (Cx) 32 in 24 human hepa...

journal_title：Journal of gastroenterology

authors： Nakashima Y,Ono T,Yamanoi A,El-Assal ON,Kohno H,Nagasue N

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Angiogenesis is essential for gastric ulcer healing. Recent results suggest that vascular endothelial growth factor receptor 1 (VEGFR1), which binds to VEGF, promotes angiogenesis. In the present study, we investigated the role of VEGFR1 signaling in gastric ulcer healing and angiogenesis. METHODS:Gastric u...

journal_title：Journal of gastroenterology

authors： Sato T,Amano H,Ito Y,Eshima K,Minamino T,Ae T,Katada C,Ohno T,Hosono K,Suzuki T,Shibuya M,Koizumi W,Majima M

更新日期：2014-03-01 00:00:00

abstract：:A 55-year-old woman was treated at our hospital for multiple sclerosis. Therapy consisted of glucocorticosteroids and cyclosporin. In the 7th week after these drugs were discontinued the patient developed acute liver failure due to fulminant hepatitis (FH) and died. Post-mortem examination showed massive liver necrosi...

journal_title：Journal of gastroenterology

authors： Funaoka M,Kato K,Komatsu M,Ono T,Hoshino T,Kato J,Kuramitsu T,Ishii T,Toyoshima I,Masamune O

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:The search is on to find more effective drug regimens for patients with severe ulcerative colitis, as conventional drugs such as sulfasalazine and its congeners fail to prevent relapse in a significant number of patients. Azathioprine has also been reported to be useful as a steroid-sparing drug in patients ...

journal_title：Journal of gastroenterology

authors： Sood A,Kaushal V,Midha V,Bhatia KL,Sood N,Malhotra V

更新日期：2002-01-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) could be curable by "immune rest" and correction of the genetic predisposition inherent in allogeneic hematopoietic stem cell transplantation. However, balancing risks against benefits remains challenging. The application of mesenchymal stem cells (MSCs) serving as a site-regulated "dr...

journal_title：Journal of gastroenterology

authors： Nagaishi K,Arimura Y,Fujimiya M

更新日期：2015-03-01 00:00:00

abstract：:Combined hepatocellular (HCC) and cholangiocellular carcinoma (CCC) (mixed carcinoma) is a rare subtype of primary hepatic carcinoma. We report a case of mixed carcinoma that developed in a non-cirrhotic liver, in a patient who was serologically negative for both hepatitis B and C viruses. A 65-year-old Japanese woman...

journal_title：Journal of gastroenterology

authors： Shiraishi M,Takushi Y,Simoji H,Oshiro T,Shinzato S,Tanigawa N,Kusano T,Muto Y

更新日期：1998-08-01 00:00:00

abstract：:A new triple therapy using a proton pump inhibitor and two antibiotics shows high efficiency against Helicobacter pylori infection. The aim of this study was to determine the optimal dose and duration of lansoprazole (LA) administration in combination with amoxicillin (AMPC) and metronidazole (MNZ). A total of 91 pati...

journal_title：Journal of gastroenterology

authors： Nishikawa K,Sugiyama T,Ishizuka J,Kudo T,Komatsu Y,Katagiri M,Sukegawa M,Kagaya H,Kudo M,Kato M,Takeda H,Toyota J,Asaka M

更新日期：1999-01-01 00:00:00

abstract：:In a pilot study of direct dissolution therapy of gallstones with methyl tert-butyl ether (MTBE), endoscopic transpapillary catheterization in the gallbladder (ETCG) was performed. Complete dissolution was seen in 8 out of 12 (66%) patients and partial dissolution was seen in 2 (16%) patients. In one of the 8 complete...

journal_title：Journal of gastroenterology

authors： Uchida N,Nakatsu T,Hirabayashi S,Minami A,Fukuma H,Ezaki T,Morshed SA,Fuke C,Ameno K,Ijiri I

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Whether mucosal inflammation affects gastric motility in patients with functional dyspepsia (FD) is controversial. Few reports discuss gastric motility in relation to histologic gastritis. We examined the relation between gastric motility and histologic gastritis in Japanese patients with FD. METHODS:Subjec...

journal_title：Journal of gastroenterology

authors： Matsumoto Y,Ito M,Kamino D,Tanaka S,Haruma K,Chayama K

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:To further clarify the clinico-epidemiological features of autoimmune pancreatitis (AIP) in Japan, we conducted the fourth nationwide epidemiological survey. METHODS:This study consisted of two stage surveys; the number of AIP patients was estimated by the first survey and their clinical features were asses...

journal_title：Journal of gastroenterology

authors： Masamune A,Kikuta K,Hamada S,Tsuji I,Takeyama Y,Shimosegawa T,Okazaki K,Collaborators.

更新日期：2020-04-01 00:00:00

abstract：:Our objective was to determine whether the prevalence of vacuolating cytotoxin production differed among Helicobacter pylori isolates obtained from patients with chronic gastritis, gastric ulcer, or duodenal ulcer. We examined the vacuolating cytotoxin production of 114 clinical H. pylori isolates in rabbit gastic epi...

journal_title：Journal of gastroenterology

authors： Kodama K,Fujioka T,Ito A,Kubota T,Murakami K,Nasu M

更新日期：1996-11-01 00:00:00

abstract：:Cholecystokinin (CCK) receptor antagonists have been reported on have an inhibitory effect on acute experimental pancreatitis, but their long-term administration is also reported to block pancreatic regeneration. We examined whether the short-term administration of KSG-504 (KSG), a synthetic CCK-A receptor antagonist,...

journal_title：Journal of gastroenterology

authors： Okumura Y,Inoue H,Fujiyama Y,Bamba T

更新日期：1995-08-01 00:00:00

abstract：:Cowden's disease, multiple hamartoma syndrome, is a dominantly inherited disorder characterized by multiple hamartomas of ectodermal, endodermal, and mesodermal origin and also by a high incidence of malignant tumors. Despite many efforts to identify the genetic alterations responsible for the syndrome, the molecular ...

journal_title：Journal of gastroenterology

authors： Suzuki T,Ichinose M,Matsubara Y,Yahagi N,Kurokawa K,Fukamachi H,Miki K

更新日期：1997-10-01 00:00:00

abstract：:Eosinophilic esophagitis (EE) is a rarely diagnosed condition involving eosinophilic infiltration of the esophageal mucosa. Here we present a case of EE in a 69-year-old Japanese man, who presented with abdominal pain, appetite loss, and a history of bronchial asthma. Laboratory findings included peripheral eosinophil...

journal_title：Journal of gastroenterology

authors： Furuta K,Adachi K,Kowari K,Mishima Y,Imaoka H,Kadota C,Koshino K,Miyake T,Kadowaki Y,Furuta K,Kazumori H,Sato S,Ishihara S,Amano Y,Honda M,Kinoshita Y

更新日期：2006-07-01 00:00:00

abstract：:Reducing the incidence of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB) is the key ultimate goal set in essentially all treatment guidelines. There has been solid evidence supporting the relationship between serum hepatitis B virus (HBV) DNA level and risk of HCC. Antiviral treatment with o...

journal_title：Journal of gastroenterology

authors： Yip TC,Lai JC,Wong GL

更新日期：2020-11-01 00:00:00

abstract：:We estimated the levels of free sialic acid and sialylated oligosaccharides excreted in the urine of normal donors (n = 10) and patients with gastric cancer (n = 6) and colorectal cancer (n = 4). The total sialic acid level in cancer patients was similar to that in normal donors. However, the ratios of glycosidically ...

journal_title：Journal of gastroenterology

authors： Shimada I,Shoji M,Futatsuya R,Katoh T,Kominato Y,Sakamoto T,Fujikura T

更新日期：1995-02-01 00:00:00

abstract：:Three-dimensional-computed tomography (3D-CT) cholangiography is a 3D shaded surface display image of the biliary tract obtained by using helical CT after intravenous cholangiography or cholangiography per percutaneous transhepatic cholangio-drainage tube. We investigated whether 3D-CT cholangiography could provide a ...

journal_title：Journal of gastroenterology

authors： Kinami S,Yao T,Kurachi M,Ishizaki Y

更新日期：1999-02-01 00:00:00

abstract：:Several components of the gastrointestinal tract including the esophagogastric junction (EGJ) show circumferential asymmetry in the formation of pathological lesions, which is caused by the morphological and functional asymmetry of the gastrointestinal tract. Pressure in the lower esophageal sphincter (LES) is higher ...

journal_title：Journal of gastroenterology

authors： Kinoshita Y,Furuta K,Adachi K,Amano Y

更新日期：2009-01-01 00:00:00

abstract：:We aimed to determine the safety and feasibility of an alternative postoperative oral intake protocol for Japanese patients who had had oncological colorectal surgery, with the goal of shortening the length of postoperative stay to the same level as that in Western countries. The subjects of the study were 42 consecut...

journal_title：Journal of gastroenterology

authors： Kawamura YJ,Uchida H,Watanabe T,Nagawa H

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Gene therapy is a promising therapeutic method but is severely hampered due to its lack of an ideal delivery system. Therefore, in this study, a nonviral and magnetic resonance imaging (MRI) visible vector, polyethylene glycol-grafted polyethylenimine and superparamagnetic iron oxide nanoparticles (PEG-g-PEI...

journal_title：Journal of gastroenterology

authors： Chen Y,Lian G,Liao C,Wang W,Zeng L,Qian C,Huang K,Shuai X

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Liver cirrhosis affects the results of many of the traditional techniques currently used to evaluate nutritional status. Our aim was to compare the traditional two-compartment model (subjective global assessment and anthropometry and blood tests) of nutritional assessment with a multicompartmental model (bod...

journal_title：Journal of gastroenterology

authors： Figueiredo FA,Perez RM,Freitas MM,Kondo M

更新日期：2006-05-01 00:00:00

abstract：:Acute and chronic pancreatitises are gastrointestinal inflammatory diseases, the incidence of which is increasing worldwide. Most (~ 80%) acute pancreatitis (AP) patients have mild disease, and about 20% have severe disease, which causes multiple organ failure and has a high mortality rate. Chronic pancreatitis (CP) i...

journal_title：Journal of gastroenterology

authors： Sato T,Shibata W,Maeda S

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:The levels of serum HER2 extracellular domain (ECD) are highly correlated with tissue HER2 status in metastatic gastric cancer (AGC). We sought to explore whether serum HER2 ECD could predict the efficacy of trastuzumab-treated HER2-positive AGC. MATERIALS AND METHODS:From 2011 to 2013, trastuzumab-treated ...

journal_title：Journal of gastroenterology

authors： Zhou J,Peng Z,Liu Y,Gong J,Zhang X,Lu M,Gao J,Li Y,Li Y,Shen L

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:The T-helper (Th)1 immune reaction is essential for the eradication of hepatitis C virus (HCV) during interferon (IFN) therapy in patients with chronic hepatitis C. Osteopontin is a cytokine crucial for the initiation of the Th1 response. Recently, we identified four single-nucleotide polymorphisms (SNPs) in...

journal_title：Journal of gastroenterology

authors： Naito M,Matsui A,Inao M,Nagoshi S,Nagano M,Ito N,Egashira T,Hashimoto M,Mishiro S,Mochida S,Fujiwara K

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Adiponectin has been shown to have suppressive effects on tumor development, but the expression of adiponectin receptors in tumor tissue has not been fully elucidated. The purpose of this study was to quantitatively evaluate the expression of two adiponectin receptors, AdipoR1 and AdipoR2, in gastric cancer ...

journal_title：Journal of gastroenterology

authors： Otani K,Kitayama J,Kamei T,Soma D,Miyato H,Yamauchi T,Kadowaki T,Nagawa H

更新日期：2010-09-01 00:00:00

abstract：:We report a patient who survived total colonic type ulcerative colitis (UC) complicated by toxic megacolon (TM), disseminated intravascular coagulation (DIC), methicillin-resistant Staphylococcus aureus infection, and phlebothrombosis. A 69-year-old man was treated for about 4 months under the diagnosis of ischemic co...

journal_title：Journal of gastroenterology

authors： Arai H,Hanai H,Furuta T,Sato Y,Yamada M,Kaneko E,Baba S,Sugimura H

更新日期：1999-06-01 00:00:00