Common processing of in vivo MR spectra.

abstract：:Current functional MRI (fMRI) approaches assess underlying neuronal activity through monitoring the related local variations in cerebral blood oxygenation, blood volume and blood flow. This vascular response is likely to vary across brain regions and across individuals, depending on the composition of the local vascul...

journal_title：NMR in biomedicine

authors： Driver ID,Andoh J,Blockley NP,Francis ST,Gowland PA,Paus T

更新日期：2015-05-01 00:00:00

abstract：:An MR thermometry method is proposed for measuring in vivo small temperature changes engendered by external RF heat sources. The method relies on reproducible and stable respiration and therefore currently applies to ventilated animals whose breathing is carefully controlled. It first consists in characterizing the st...

journal_title：NMR in biomedicine

authors： Boulant N,Bottlaender M,Uhrig L,Giacomini E,Luong M,Amadon A,Massire A,Larrat B,Vignaud A

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to investigate proton changes of the parotid gland after gustatory stimulation by semi-quantitative parameters and an empirical mathematical model (EMM) using high-temporal-resolution, double-echo, echo-planar imaging (EPI). Approved by a local institutional review board, this study examined ...

journal_title：NMR in biomedicine

authors： Liu YJ,Lee YH,Chang HC,Chiu HC,Chiu TW,Hsu K,Pen CM,Hsu HH,Juan CJ

更新日期：2018-03-01 00:00:00

abstract：:Non-alcoholic steatohepatitis (NASH) is characterized at histology by steatosis, hepatocyte ballooning and inflammatory infiltrates, with or without fibrosis. Although diamagnetic material in fibrosis and inflammation can be detected with quantitative susceptibility imaging, fatty acid composition changes in NASH rela...

journal_title：NMR in biomedicine

authors： Leporq B,Lambert SA,Ronot M,Vilgrain V,Van Beers BE

更新日期：2017-10-01 00:00:00

abstract：:Cross-talk between adipose tissue and liver is disturbed in the metabolic syndrome. Moreover, the relative fatty acid composition of adipose and liver fat is poorly characterized. Long-TE (1)H MRS can determine the unsaturation and polyunsaturation of adipose tissue. The aim of this study was to use long-TE (1)H MRS t...

journal_title：NMR in biomedicine

authors： Lundbom J,Hakkarainen A,Söderlund S,Westerbacka J,Lundbom N,Taskinen MR

更新日期：2011-04-01 00:00:00

abstract：:The intimal and medial linings of the pulmonary artery consist largely of vascular endothelial cells (VECs) and vascular smooth muscle cells (VSMCs), respectively. The migration of these cell types to a potential tissue-engineered pulmonary valve (TEPV) implant process is therefore of interest in understanding the val...

journal_title：NMR in biomedicine

authors： Ramaswamy S,Schornack PA,Smelko AG,Boronyak SM,Ivanova J,Mayer JE Jr,Sacks MS

更新日期：2012-03-01 00:00:00

abstract：:Glucose metabolism in control and estrogen stimulated rat uteri was investigated using 13C NMR spectroscopy. By employing an NMR adapted perifusion system, and developing protocols and methods based on the application of [1-13C]glucose labeling, it was possible to measure, with a temporal resolution of 10 min, the kin...

journal_title：NMR in biomedicine

authors： Shinkarenko L,Kaye AM,Degani H

更新日期：1994-08-01 00:00:00

abstract：:We review several methods that have been developed to infer microstructural and physiological information about isotropic and anisotropic tissues from diffusion weighted images (DWIs). These include Diffusion Imaging (DI), Diffusion Tensor Imaging (DTI), isotropically weighted imaging, and q-space imaging. Just as DI ...

journal_title：NMR in biomedicine

authors： Basser PJ

更新日期：1995-11-01 00:00:00

abstract：:Lung cancer is a primary cause of cancer deaths worldwide. Timely detection of this pathology is necessary to delay or interrupt lung cancer progression, ultimately resulting in a possible better prognosis for the patient. In this context, magnetic resonance imaging (MRI) is especially promising. Ultra-short echo time...

journal_title：NMR in biomedicine

authors： Bianchi A,Gobbo OL,Dufort S,Sancey L,Lux F,Tillement O,Coll JL,Crémillieux Y

更新日期：2017-11-01 00:00:00

abstract：:Quantitative mapping of MR tissue parameters such as the spin-lattice relaxation time (T1 ), the spin-spin relaxation time (T2 ), and the spin-lattice relaxation in the rotating frame (T1ρ ), referred to as MR relaxometry in general, has demonstrated improved assessment in a wide range of clinical applications. Compar...

journal_title：NMR in biomedicine

authors： Feng L,Ma D,Liu F

更新日期：2020-10-15 00:00:00

abstract：:Qualitative and quantitative (1) H NMR analysis of lipid extracts of gallbladder tissue in chronic cholecystitis (CC, benign) (n = 14), xanthogranulomatous cholecystitis (XGC, intermediate) (n = 9) and gallbladder cancer (GBC, malignant) (n = 8) was carried out to understand the mechanisms involved in the transformati...

journal_title：NMR in biomedicine

authors： Jayalakshmi K,Sonkar K,Behari A,Kapoor VK,Sinha N

更新日期：2011-05-01 00:00:00

abstract：:In recent years considerable effort has been devoted to applying pattern recognition techniques to the complex task of data analysis in magnetic resonance spectroscopy. It may be argued that such techniques will facilitate putting MRS technology to practical clinical use. This paper reviews approaches of pattern recog...

journal_title：NMR in biomedicine

authors： el-Deredy W

更新日期：1997-05-01 00:00:00

abstract：:A special characteristic of the brain is the usage of lactate as alternative fuel instead of glucose to preserve its energy homeostasis. This physiological function is valid for sufficient cerebral glucose supply, as well as presumably during hypoglycemia, given that exogenous lactate infusion suppresses hormonal coun...

journal_title：NMR in biomedicine

authors： Richter J,Rabe D,Duysen K,Melchert UH,Oltmanns KM

更新日期：2019-11-01 00:00:00

abstract：:1H NMR spin-echo spectroscopy has been used to study the metabolism of exogenous compounds in human erythrocytes. The non-invasive nature of the technique and the continuous monitoring makes it ideal to investigate both the conversion of substrates and the occurrence and the nature of the products. Hydrolysis rates ma...

journal_title：NMR in biomedicine

authors： Skibsted U,Hansen PE

更新日期：1990-12-01 00:00:00

abstract：:The aim of this study was to acquire the transient MRI signal of hyperpolarized tracers and their metabolites efficiently, for which specialized imaging sequences are required. In this work, a multi-echo balanced steady-state free precession (me-bSSFP) sequence with Iterative Decomposition with Echo Asymmetry and Leas...

journal_title：NMR in biomedicine

authors： Müller CA,Hundshammer C,Braeuer M,Skinner JG,Berner S,Leupold J,Düwel S,Nekolla SG,Månsson S,Hansen AE,von Elverfeldt D,Ardenkjaer-Larsen JH,Schilling F,Schwaiger M,Hennig J,Hövener JB

更新日期：2020-06-01 00:00:00

abstract：:High-energy phosphate metabolism, which allows the synthesis and regeneration of adenosine triphosphate (ATP), is a vital process for neuronal survival and activity. In particular, creatine kinase (CK) serves as an energy reservoir for the rapid buffering of ATP levels. Altered CK enzyme activity, reflecting compromis...

journal_title：NMR in biomedicine

authors： Jeong EK,Sung YH,Kim SE,Zuo C,Shi X,Mellon EA,Renshaw PF

更新日期：2011-08-01 00:00:00

abstract：:d-amino acid oxidase (DAO) is a peroxisomal enzyme that catalyzes the oxidative deamination of several neutral and basic d-amino acids to their corresponding α-keto acids. In most mammalian species studied, high DAO activity is found in the kidney, liver, brain and polymorphonuclear leukocytes, and its main function i...

journal_title：NMR in biomedicine

authors： Radaelli A,Gruetter R,Yoshihara HAI

更新日期：2020-07-01 00:00:00

abstract：:Chronic pain is a major problem for the individual and for society. Despite a range of drugs being available to treat chronic pain, only inadequate pain relief can be achieved for many patients. There is therefore a need for the development of new analgesic compounds. The assessment of pain depends to date entirely on...

journal_title：NMR in biomedicine

authors： Schweinhardt P,Bountra C,Tracey I

更新日期：2006-10-01 00:00:00

abstract：:Owing to the small quantity of tissue available in human biopsy specimens, aqueous and lipid components often have to be determined in the same tissue sample. Perchloric acid (PCA) used for the extraction of aqueous metabolites has a deleterious effect on lipid components; the severity of the damage is not known. In t...

journal_title：NMR in biomedicine

authors： Srivastava NK,Pradhan S,Mittal B,Kumar R,Pandey CM,Gowda GA

更新日期：2008-02-01 00:00:00

abstract：:An optimized semi-LASER sequence that is capable of acquiring artefact-free data with an echo time (TE) of 20.1 ms on a standard clinical 3 T MR system was developed. Simulations were performed to determine the optimal TEs that minimize the expected Cramér-Rao lower bound (CRLB) as proxy for quantification accuracy of...

journal_title：NMR in biomedicine

authors： Landheer K,Gajdošík M,Juchem C

更新日期：2020-09-01 00:00:00

abstract：:The steady-state distribution of the general anesthetic halothane in different rat tissues, including a renal adenocarcinoma with and without hyperthermia treatment, has been evaluated by in vivo 19F NMR spectroscopy. The 19F spectra of halothane (which is a hydrophobic probe) from within tissue show differences in th...

journal_title：NMR in biomedicine

authors： Burt CT,Moore RR,Roberts MF

更新日期：1993-09-01 00:00:00

abstract：:High grade and metastatic brain tumours exhibit considerable spatial variations in proliferation, angiogenesis, invasion, necrosis and oedema. Vascular heterogeneity arising from vascular co-option in regions of invasive growth (in which the blood-brain barrier remains intact) and neoangiogenesis is a major challenge ...

journal_title：NMR in biomedicine

authors： Boult JK,Borri M,Jury A,Popov S,Box G,Perryman L,Eccles SA,Jones C,Robinson SP

更新日期：2016-11-01 00:00:00

abstract：:Increased lactate production through glycolysis in aerobic conditions is a hallmark of cancer. Some anticancer drugs have been designed to exploit elevated glycolysis in cancer cells. For example, lonidamine (LND) inhibits lactate transport, leading to intracellular acidification in cancer cells. Chemical exchange sat...

journal_title：NMR in biomedicine

authors： McVicar N,Li AX,Meakin SO,Bartha R

更新日期：2015-05-01 00:00:00

abstract：:Dynamic contrast-enhanced MRI (DCE MRI) has been used to study tumor response to treatment for many years. In this study, the modified full width at half-maximum (mFWHM), calculated from the wash-in slope histogram, is proposed as a parameter for the evaluation of changes in tumor heterogeneity which respond to radiot...

journal_title：NMR in biomedicine

authors： Peng SL,Chen CF,Liu HL,Lui CC,Huang YJ,Lee TH,Chang CC,Wang FN

更新日期：2013-04-01 00:00:00

abstract：:The main aim of this study was to employ high-resolution MRI to investigate the spatiotemporal development of pathological features associated with contusive spinal cord injury (SCI) in mice. Experimental mice were subjected to either sham surgery or moderate contusive SCI. A 16.4-T small-animal MR system was employed...

journal_title：NMR in biomedicine

authors： Blomster LV,Cowin GJ,Kurniawan ND,Ruitenberg MJ

更新日期：2013-02-01 00:00:00

abstract：:MRI detects changes in blood-oxygenation-level dependent (BOLD) contrast in tumors caused by tumor oxygenating agents. These changes can be used to guide the design of improved tumor oxygenating treatments (TOXs). The conventional approach to detection of BOLD effects assumes that the water resonance is a single, homo...

journal_title：NMR in biomedicine

authors： Al-Hallaq HA,Fan X,Zamora M,River JN,Moulder JE,Karczmar GS

更新日期：2002-02-01 00:00:00

abstract：:Two FDA-approved agents, ferumoxides (Feridex), a suspension of superparamagnetic iron oxide (SPIO) nanoparticles and protamine sulfate, a drug used to reverse heparin anticoagulation, can be complexed and used to label cells magnetically ex vivo. Labeling stem cells with ferumoxides-protamine sulfate (FePro) complexe...

journal_title：NMR in biomedicine

authors： Arbab AS,Yocum GT,Rad AM,Khakoo AY,Fellowes V,Read EJ,Frank JA

更新日期：2005-12-01 00:00:00

abstract：:The purpose of this work was to assess the reproducibility of percentage of ventilated lung volume (PV) measured from hyperpolarized (HP) (3)He and (1)H anatomical images acquired in the same breath-hold when compared with PV measured from (3)He and (1)H images from separate breath-holds. Volumetric (3)He ventilation ...

journal_title：NMR in biomedicine

authors： Horn FC,Tahir BA,Stewart NJ,Collier GJ,Norquay G,Leung G,Ireland RH,Parra-Robles J,Marshall H,Wild JM

更新日期：2014-12-01 00:00:00

abstract：:This study aimed to demonstrate a reliable automatic segmentation method for independently separating reduced diffusion and decreased perfusion areas in ischemic stroke brains using constrained nonnegative matrix factorization (cNMF) pattern recognition in directional intravoxel incoherent motion MRI (IVIM-MRI). First...

journal_title：NMR in biomedicine

authors： Jang M,Jin S,Kang M,Han S,Cho H

更新日期：2020-05-01 00:00:00

abstract：:Q-ball imaging (QBI) is an imaging technique that is capable of resolving intravoxel fiber crossings; however, the signal readout based on echo-planar imaging (EPI) introduces geometric distortions in the presence of susceptibility gradients. This study proposes an imaging technique that reduces susceptibility distort...

journal_title：NMR in biomedicine

authors： Chou MC,Huang TY,Chung HW,Hsieh TJ,Chang HC,Chen CY

更新日期：2013-12-01 00:00:00