Gene expression in neurotrauma.

Abstract:

:It has been established that following injury to the central nervous system two types of damage take place, the initial insult and the secondary response to injury. This review will focus on the secondary molecular aspects of neurotrauma. These responses may be either deleterious or have protective effects upon the injured cell population. Molecular responses include the regulation of genes which change cellular architecture, up-regulate of growth factors, induce reparative stress responses, influence apoptosis and regulate the transcriptional process. The purpose of this study is to provide the reader with a brief overview of some of the molecular mechanisms which are activated following a neurological insult.

journal_name

Neurol Res

journal_title

Neurological research

authors

Dutcher SA,Michael DB

doi

10.1179/016164101101198343

subject

Has Abstract

pub_date

2001-03-01 00:00:00

pages

203-6

issue

2-3

eissn

0161-6412

issn

1743-1328

journal_volume

23

pub_type

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