Inflammatory responses in influenza A virus infection.

abstract：:Human metapneumovirus (HMPV) is a major cause of morbidity and mortality from acute lower respiratory tract illness, with most individuals seropositive by age five. Despite the presence of neutralizing antibodies, secondary infections are common and can be severe in young, elderly, and immunocompromised persons. Precl...

journal_title：Vaccine

authors： Hastings AK,Gilchuk P,Joyce S,Williams JV

更新日期：2016-05-23 00:00:00

abstract：:The aim of this study was to characterize the adverse events of attenuated measles vaccine in mainland China. We carried out prospective follow-up of adverse events after mass measles immunization practices, categorizing them into two groups: allergic reactions and serious adverse events. The incidence of anaphylaxis ...

journal_title：Vaccine

authors： Shu M,Liu Q,Wang J,Ao R,Yang C,Fang G,Wan C,Guo W

更新日期：2011-04-18 00:00:00

abstract：:Foot-and-mouth disease (FMD) is present in much of Turkey and its control is largely based on vaccination. The arrival of the FMD Asia-1 serotype in Turkey in 2011 caused particular concern, spreading rapidly westwards across the country towards the FMD free European Union. With no prior natural immunity, control of s...

journal_title：Vaccine

authors： Knight-Jones TJ,Bulut AN,Gubbins S,Stärk KD,Pfeiffer DU,Sumption KJ,Paton DJ

更新日期：2014-04-01 00:00:00

abstract：:A plasmid DNA vaccine encoding the circumsporozoite protein of malaria (pCSP) induces protective immunity in adult mice but persistent tolerance when administered to neonates. In an effort to improve antigen presenting cell (APC) function in newborns, we co-administered pCSP with a plasmid encoding granulocyte-macroph...

journal_title：Vaccine

authors： Ishii KJ,Weiss WR,Klinman DM

更新日期：1999-11-12 00:00:00

abstract：INTRODUCTION:Despite the enormous benefits of childhood and maternal immunisation to individual and population health, the uptake of maternal vaccines during pregnancy remains suboptimal. Midwives are a trusted information source for parents and play an important role in the provision of immunisation information. Under...

journal_title：Vaccine

authors： Frawley JE,McKenzie K,Sinclair L,Cummins A,Wardle J,Hall H

更新日期：2020-01-10 00:00:00

abstract：:Streptococcus pneumoniae is an important pathogen worldwide. Accurate sampling of S. pneumoniae carriage is central to surveillance studies before and following conjugate vaccination programmes to combat pneumococcal disease. Any bias introduced during sampling will affect downstream recovery and typing. Many variable...

journal_title：Vaccine

authors： Gladstone RA,Jefferies JM,Faust SN,Clarke SC

更新日期：2012-11-06 00:00:00

abstract：:Taking the results of a prospective cohort study by our group that evaluated the effectiveness of the inactivated subunit virosomal influenza vaccine (Inflexal V), Crucell-Berna) in the prevention of influenza-related diseases and the reduction of its negative economic consequences, the economic costs and benefits for...

journal_title：Vaccine

authors： Salleras L,Navas E,Domínguez A,Ibáñez D,Prat A,Garrido P,Asenjo MA,Torner N

更新日期：2009-05-26 00:00:00

abstract：:To test whether inactivated influenza vaccines distributed during the 2003-2004 influenza season in the northern hemisphere were able to confer protection against the mismatched variant A/Fujian/411/2002 virus strain, we measured haemagglutination inhibiting (HI) antibodies in elderly subjects vaccinated with three in...

journal_title：Vaccine

authors： Del Giudice G,Hilbert AK,Bugarini R,Minutello A,Popova O,Toneatto D,Schoendorf I,Borkowski A,Rappuoli R,Podda A

更新日期：2006-04-12 00:00:00

abstract：:The purpose of the present study was to compare serum and mucosal immune responses following either aerosol (Aer) or subcutaneous (SQ) measles immunization of Mexican school children. A cohort of 49 children from 6 to 7 years of age received either Aer ( n = 22) or SQ ( n = 27) Edmonston-Zagreb (EZ) measles vaccine. S...

journal_title：Vaccine

authors： Bellanti JA,Zeligs BJ,Mendez-Inocencio J,García-Garcia ML,Islas-Romero R,Omidvar B,Omidvar J,Kim G,Fernandez De Castro J,Sepulveda Amor J,Walls L,Bellini WJ,Valdespino-Gomez JL

更新日期：2004-03-12 00:00:00

abstract：:In this review, published peer-reviewed preclinical studies using prime-boost tuberculosis (TB) vaccine regimens in animal challenge models for tuberculosis have been evaluated. These studies have been divided into groups that describe prime-boost vaccine combinations that performed better than, equivalent to, or wors...

journal_title：Vaccine

authors： Brennan MJ,Clagett B,Fitzgerald H,Chen V,Williams A,Izzo AA,Barker LF

更新日期：2012-04-16 00:00:00

abstract：:A mass vaccination campaign against influenza A/H1N1 was launched in France in October 2009. Vaccination was offered free of charge to the entire population according to a pre-defined order of priority. Demographic data and data on vaccinations given were recorded in a dedicated database. We analysed vaccine uptake by...

journal_title：Vaccine

authors： Bone A,Guthmann JP,Nicolau J,Lévy-Bruhl D

更新日期：2010-11-29 00:00:00

abstract：BACKGROUND:Few studies report the effectiveness of trivalent inactivated influenza vaccine (TIV) in preventing hospitalisation for influenza-confirmed respiratory infections. Using a prospective surveillance platform, this study reports the first such estimate from a well-defined ethnically diverse population in New Ze...

journal_title：Vaccine

authors： Turner N,Pierse N,Bissielo A,Huang QS,Baker MG,Widdowson MA,Kelly H,SHIVERS investigation team.

更新日期：2014-06-17 00:00:00

abstract：:As part of a larger study exploring how European citizens' balance issues of public and private interest and the extent to which they are prepared to accept State intervention on a range of public health issues, focus group participants were asked whether childhood immunisation should be a matter of parental choice or...

journal_title：Vaccine

authors： Moran N,Shickle D,Richardson E

更新日期：2008-01-17 00:00:00

abstract：:This work describes the formulation design and development of a novel protein based adjuvant, a double mutant of heat labile toxin (dmLT), based on knowledge of the protein's structural integrity and physicochemical degradation pathways. Various classes of pharmaceutical excipients were screened for their stabilizing ...

journal_title：Vaccine

authors： Toprani VM,Sahni N,Hickey JM,Robertson GA,Middaugh CR,Joshi SB,Volkin DB

更新日期：2017-10-04 00:00:00

abstract：:Influenza is a significant cause of morbidity and mortality for pregnant women and infants worldwide. Influenza vaccination during pregnancy has been shown to be safe and highly effective and should be recommended for all pregnant women before the influenza season. Despite existing recommendations, the vaccine is unde...

journal_title：Vaccine

authors： Blanchard-Rohner G,Siegrist CA

更新日期：2011-10-06 00:00:00

abstract：:Sin Nombre virus (SNV; family Bunyaviridae, genus Hantavirus) causes a hemorrhagic fever known as hantavirus pulmonary syndrome (HPS) in North America. There have been approximately 200 fatal cases of HPS in the United States since 1993, predominantly in healthy working-age males (case fatality rate 35%). There are no...

journal_title：Vaccine

authors： Hooper JW,Josleyn M,Ballantyne J,Brocato R

更新日期：2013-09-13 00:00:00

abstract：:Dengue fever is a growing public health concern around the world and despite vaccine development efforts, there are currently no effective dengue vaccines. In the present study we report the induction of protective antibodies against dengue virus by DNA immunization with domain III (DIII) region of the envelope protei...

journal_title：Vaccine

authors： Mota J,Acosta M,Argotte R,Figueroa R,Méndez A,Ramos C

更新日期：2005-05-16 00:00:00

abstract：:The potential outcomes of a Phase II schistosomiasis vaccine trial are explored using mathematical models which assume some natural immunity and a vaccine providing partial protection for a limited time. Analyses suggest that vaccination may have only a limited impact on life-long cumulative worm burdens and may lead ...

journal_title：Vaccine

authors： Woolhouse ME

更新日期：1995-08-01 00:00:00

abstract：:The vast majority of women infected with human immunodeficiency virus (HIV) will be co-infected with human papillomavirus (HPV). The interaction between the two sexually transmitted infections appears to be related to the alteration in cell-mediated immunity in HIV infected persons, increased susceptibility, and possi...

journal_title：Vaccine

authors： Denny LA,Franceschi S,de Sanjosé S,Heard I,Moscicki AB,Palefsky J

更新日期：2012-11-20 00:00:00

abstract：:This paper presents the results of a global survey that aimed to collect information on country's immunization policy development processes, particularly on the presence and function of national Immunization Technical Advisory Groups (ITAGs). Characteristics of national ITAGs are described as well as attributes of the...

journal_title：Vaccine

authors： Bryson M,Duclos P,Jolly A,Cakmak N

更新日期：2010-04-19 00:00:00

abstract：:Recently, efforts have been made to fill a so-called "vaccine gap" between Japan and other countries; however, more work remains. Concerns about adverse events following immunization (AEFI) resulted in an historically passive approach to policy making in the National Immunization Program (NIP). For example, reports of...

journal_title：Vaccine

authors： Katsuta T,Moser CA,Feemster KA,Saitoh A,Offit PA

更新日期：2020-10-27 00:00:00

abstract：:A rapid and sensitive assay using surface plasmon resonance (SPR) immunoassay has been developed for the detection of Clostridium perfringens beta-toxin. The SPR immunoassay was conducted off-line by passing fermentation broth by a sensor chip coated with a monoclonal antibody specific for C. perfringens beta-toxin. Q...

journal_title：Vaccine

authors： Hsieh HV,Stewart B,Hauer P,Haaland P,Campbell R

更新日期：1998-05-01 00:00:00

abstract：:Despite of highly active antiretroviral therapy, the response to vaccines in HIV-infected children is poor and short-lived, probably due to a defect in cellular immune responses. We compared the cellular immune response (assessed in terms of IFN-γ production) to tetanus toxoid and to cytomegalovirus in a series of 13 ...

journal_title：Vaccine

authors： Alsina L,Noguera-Julian A,Fortuny C

更新日期：2013-05-07 00:00:00

abstract：:Susceptible dairy cattle were immunized with attenuated, live calf-derived, in vitro-cultured or biologically cloned Babesia bovis, with non-viable exoantigens, or with recombinant rhoptry-associated protein 1 (rRAP1). Antibody response assessed by the indirect fluorescent assay (IFA) and by the growth inhibition acti...

journal_title：Vaccine

authors： Fish L,Leibovich B,Krigel Y,McElwain T,Shkap V

更新日期：2008-12-19 00:00:00

abstract：:Recombinant Adenovirus serotype 5 (Ad5) vectors have been used as vaccine platforms in numerous animal and human clinical studies. The immune response induced by Ad5 vaccines can be mitigated due to pre-existing Ad5 immunity. We previously reported the use of a novel Ad5 platform to induce cellular immune responses (C...

journal_title：Vaccine

authors： Gabitzsch ES,Xu Y,Yoshida LH,Balint J,Amalfitano A,Jones FR

更新日期：2009-10-30 00:00:00

abstract：:The hemagglutinin/protease (HA/P) seems to be an attractive locus for the insertion of heterologous tags in live cholera vaccine strains. A deltaCTXphi spontaneous mutant derived from a pathogenic strain of O139 Vibrio cholerae was sequentially manipulated to obtain hapA Colon, two colons celA derivatives which were l...

journal_title：Vaccine

authors： Ledón T,Valle E,Valmaseda T,Cedré B,Campos J,Rodríguez BL,Marrero K,García H,García L,Fando R

更新日期：2003-03-07 00:00:00

abstract：:Former investigations demonstrated that the envelope glycoprotein E2 could protect pigs from classical swine fever virus (CSFV). Based on these findings, we prepared synthetic peptide vaccine using E2 N-terminal antigenic units B/C and hoped to induce protective activity against lethal challenge of virulent CSFV strai...

journal_title：Vaccine

authors： Dong XN,Wei K,Liu ZQ,Chen YH

更新日期：2002-12-13 00:00:00

abstract：:The continuous outbreaks of fatal Newcastle disease (ND) in commercial poultry flocks demonstrate that current vaccination strategies are not fully efficacious and should be improved by new generation of vaccines. In this context, maternally immune conventional layer chickens were vaccinated in ovo with a turkey herpe...

journal_title：Vaccine

authors： Rauw F,Gardin Y,Palya V,Anbari S,Lemaire S,Boschmans M,van den Berg T,Lambrecht B

更新日期：2010-01-08 00:00:00

abstract：BACKGROUND:We have previously developed a recombinant avian avulavirus serotype 10 (rAAvV-10/HA) expressing the hemagglutinin (HA) gene of a highly pathogenic avian influenza virus (HPAIV) as an emergency vaccine for poultry. rAAvV-10/HA can overcome the activity of the anti-AAvV-1 (Newcastle disease virus) antibody ac...

journal_title：Vaccine

authors： Tsunekuni R,Tanikawa T,Nakaya T,Saito T

更新日期：2020-01-22 00:00:00

abstract：:Despite a critical need for a respiratory syncytial virus (RSV) vaccine and decades of development efforts, a vaccine to protect infants, elderly, and other at-risk populations from RSV infection remains elusive. We have previously generated a new, live-attenuated vaccine candidate against RSV using rational, computer...

journal_title：Vaccine

authors： Mueller S,Stauft CB,Kalkeri R,Koidei F,Kushnir A,Tasker S,Coleman JR

更新日期：2020-03-23 00:00:00