当前位置： SCI文献检索 > RESPIRATORY MEDICINE期刊下所有文献 > Asthma from childhood to adulthood: course and outcome of lung function.

Asthma from childhood to adulthood: course and outcome of lung function.

Abstract：

:Lung function (FEV1 before and after bronchodilatation) was studied prospectively over five visits in 55 asthmatic children (28 boys) from childhood to adulthood (age 30). At the last follow-up recordings were made at rest, after cold air challenge (CACh), and after bronchodilatation. Results were related to clinical asthma scoring and to sensitization to furred animals, as described in a companion paper. Lung function outcome was shown to be influenced by initial FEV1 (% predicted) and gender, but not by initial asthma severity or sensitization. FEV1 (% predicted) was higher in females than in males over the first two follow-ups, but the reverse was found over the subsequent visits. It deteriorated from childhood to adulthood in the females but improved in the males. In adulthood the females (for height 170 cm) had a steeper normalized annual fall in post-bronchodilator FEV1 than the males (55 +/- 38 vs. 25 +/- 36 ml; P = 0.006). The degree of bronchial hyperresponsiveness was associated significantly with asthma severity and the extent of sensitization to furred animals, but not with gender. The results indicate a better lung function outcome for asthmatic boys than for girls, confirming trends seen in clinical asthma severity. In adulthood the extent of sensitization to relevant perennial inhaled allergens significantly influences airway responsiveness and asthma severity, but not lung function.

journal_name

Respir Med

journal_title

Respiratory medicine

authors

Gustafsson PM,Kjellman B

doi

10.1053/rmed.1999.0763

subject

Has Abstract

pub_date

2000-05-01 00:00:00

pages

466-74

issue

5

eissn

0954-6111

issn

1532-3064

pii

S0954-6111(99)90763-1

journal_volume

94

pub_type

杂志文章

相关文献

RESPIRATORY MEDICINE文献大全
  • Dental caries is associated with lower respiratory tract infections: A population-based cohort study.

    abstract：INTRODUCTION:Dental caries and respiratory tract infections are among the most common infectious diseases worldwide and they both are appearing in the respiratory system. However, their relations are still unclear. This study investigated the association of dental caries on the risk of lower respiratory tract infection...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2019.09.002

    authors： Mehtonen IT,Rantala AK,Hugg TT,Jaakkola MS,Jaakkola JJK

    更新日期：2019-01-01 00:00:00

  • Chest low-dose computed tomography in neutropenic acute myeloid leukaemia patients.

    abstract：BACKGROUND:We aimed to compare chest low-dose computed tomography (LDCT) with chest radiography (CXR) in the assessment of febrile acute myeloid leukaemia neutropenic patients. METHODS:A prospective non-randomized study was carried out between 30 May, 2003 and 3 June, 2004 in consecutive neutropenic patients who requi...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2009.11.003

    authors： Patsios D,Maimon N,Chung T,Roberts H,Disperati P,Minden M,Paul N

    更新日期：2010-04-01 00:00:00

  • Extrinsic allergic alveolitis: problems in diagnosis and a potential use for computed tomography.

    abstract：:Bird fancier's lung, the most common form of extrinsic allergic alveolitis in Britain, can be a difficult diagnostic problem. The symptoms are non-specific, often insidious in onset and frequently misdiagnosed as influenza or a viral or bacterial pneumonia. Frequently there is a delay in eliciting the history of expos...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/s0954-6111(06)80230-1

    authors： Vincent JM,Flower CD,Shneerson JM,Stewart S

    更新日期：1992-03-01 00:00:00

  • A high incidence of asthma and respiratory symptoms in 4-11 year old children.

    abstract：:A study assessing the prevalence of respiratory symptoms in two primary schools in Birmingham, U.K. was performed. A questionnaire was delivered to pupils in both schools after which three open days were conducted in one of the schools, where probable asthmatics were identified and referred to their General Practition...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/s0954-6111(06)80007-7

    authors： Ayres JG,Pansari S,Weller PH,Sykes A,Williams J,Butler N,Low D

    更新日期：1992-09-01 00:00:00

  • Quality control for multiple breath washout tests in multicentre bronchiectasis studies: Experiences from the BRONCH-UK clinimetrics study.

    abstract：INTRODUCTION:Multiple Breath Washout (MBW) to measure Lung Clearance Index (LCI) is increasingly being used as a secondary endpoint in multicentre bronchiectasis studies. LCI data quality control or "over-reading" is resource intensive and the impact is unclear. OBJECTIVES:To assess the proportion of MBW tests deemed ...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2018.10.030

    authors： O'Neill K,Lakshmipathy GR,Ferguson K,Cosgrove D,Hill AT,Loebinger MR,Carroll M,Chalmers JD,Gatheral T,Johnson C,DeSoyza A,Hurst JR,Bradbury I,Elborn JS,Bradley JM

    更新日期：2018-12-01 00:00:00

  • A study of loculated tuberculous pleural effusions treated with intrapleural urokinase.

    abstract：AIM:To assess the effect of intrapleural urokinase, vis-à-vis simple pleural drainage, on residual pleural thickening in a series of patients suffering from loculated tuberculous pleural effusion. PATIENTS AND METHOD:Twenty-nine patients (21 males and 8 females) with loculated pleural effusion were studied. These pati...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.rmed.2006.02.010

    authors： Cases Viedma E,Lorenzo Dus MJ,González-Molina A,Sanchis Aldás JL

    更新日期：2006-11-01 00:00:00

  • Serum latent transforming growth factor-β binding protein 4 as a novel biomarker for idiopathic pleuroparenchymal fibroelastosis.

    abstract：BACKGROUND:Idiopathic pleuroparenchymal fibroelastosis (IPPFE) is a rare idiopathic interstitial pneumonia characterized by an upper lobe-dominant interstitial increase in predominantly elastic fibers. The accumulation of cases has resulted in a refinement of the disease concept, but there are no blood biomarkers to ai...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2020.106077

    authors： Kinoshita Y,Ikeda T,Kushima H,Fujita M,Nakamura T,Nabeshima K,Ishii H

    更新日期：2020-09-01 00:00:00

  • Ethnic and racial differences in the presence of idiopathic pulmonary fibrosis at death.

    abstract：BACKGROUND:In studies of idiopathic pulmonary fibrosis (IPF), whites makeup the vast majority of subjects. Whether ethnic/racial differences in idiopathic pulmonary fibrosis occur in the general population is unknown. METHODS:To compare the presence of IPF between ethnic/racial groups of U.S. decedents from 1989 to 20...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2012.01.002

    authors： Swigris JJ,Olson AL,Huie TJ,Fernandez-Perez ER,Solomon J,Sprunger D,Brown KK

    更新日期：2012-04-01 00:00:00

  • Long-term non-invasive ventilation in COPD after acute-on-chronic respiratory failure.

    abstract：BACKGROUND:COPD patients who remain hypercapnic after acute respiratory failure requiring mechanical ventilation have a poor prognosis. Long-term nocturnal non-invasive ventilation (NIV) may be beneficial for these patients. We hypothesized that stable patients on long-term NIV would experience clinical worsening after...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.rmed.2010.09.005

    authors： Funk GC,Breyer MK,Burghuber OC,Kink E,Kirchheiner K,Kohansal R,Schmidt I,Hartl S

    更新日期：2011-03-01 00:00:00

  • Are the results of early long-term trials of sodium cromoglycate valid?

    abstract：:The first long-term study of sodium cromoglycate, reported in 1972, demonstrated the effectiveness of sodium cromoglycate in controlling asthma. The trial had various limitations, but more recent trials have been designed so that they overcome some of these problems. Results of these trials validate the results obtain...

    journal_title：Respiratory medicine

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0954-6111(89)80244-6

    authors： Turner-Warwick M

    更新日期：1989-05-01 00:00:00

  • Minimal (clinically) important differences for the Fatigue Assessment Scale in sarcoidosis.

    abstract：OBJECTIVE:The usefulness of any questionnaire in clinical management and research trials depends on its ability to indicate a likelihood of treatment success during follow-up. The Minimal Clinically Important Difference (MCID) reflects a clinically relevant change score. The aim of this study was to estimate the MCID f...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2011.05.004

    authors： de Kleijn WP,De Vries J,Wijnen PA,Drent M

    更新日期：2011-09-01 00:00:00

  • Methodological improvements for measuring eicosanoids and cytokines in exhaled breath condensate.

    abstract：BACKGROUND:Exhaled breath condensate (EBC) is simple to collect and as such a non-invasive method that has attracted substantial interest in the last few years. However, several methodological concerns have been raised and it has been difficult to reproduce results between different centres. Because of low concentratio...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2005.04.007

    authors： Tufvesson E,Bjermer L

    更新日期：2006-01-01 00:00:00

  • Changes in airway hyperresponsiveness following smoking cessation: comparisons between Mch and AMP.

    abstract：BACKGROUND:Given the observed association between smoking, inflammation and airway hyperresponsiveness (AHR) one may predict that smoking cessation may improve AHR. However, only a few studies have investigated the effect of smoking on AHR and their results appear to be conflicting depending on the stimulus used in the...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2007.09.004

    authors： Piccillo G,Caponnetto P,Barton S,Russo C,Origlio A,Bonaccorsi A,Di Maria A,Oliveri C,Polosa R

    更新日期：2008-02-01 00:00:00

  • Salmeterol provides prolonged protection against exercise-induced bronchoconstriction in a majority of subjects with mild, stable asthma.

    abstract：:In patients with asthma, exercise-induced symptoms are well recognized and frequently limiting. Currently available beta 2-receptor agonists have a short duration of action and breakthrough symptoms may occur. We studied the efficacy of the recently developed long acting inhaled beta 2-agonist salmeterol with respect ...

    journal_title：Respiratory medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0954-6111(93)90070-g

    authors： Newnham DM,Ingram CG,Earnshaw J,Palmer JB,Dhillon DP

    更新日期：1993-08-01 00:00:00

  • The role of microRNAs in chronic pseudomonas lung infection in Cystic fibrosis.

    abstract：BACKGROUND:Cystic Fibrosis (CF) is the most common life limiting genetic disorder, characterized by chronic respiratory failure secondary to inflammation and chronic bacterial lung infection. Pseudomonas aeruginosa lung infection is associated with more severe lung disease and rapid progression of respiratory failure w...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2019.04.012

    authors： Fesen K,Silveyra P,Fuentes N,Nicoleau M,Rivera L,Kitch D,Graff GR,Siddaiah R

    更新日期：2019-05-01 00:00:00

  • Pleural manometry in patients with pleural diseases - the usefulness in clinical practice.

    abstract：:Although pleural manometry is a relatively simple medical procedure it is only occasionally used to follow pleural pressure (Ppl) changes during a therapeutic thoracentesis and pneumothorax drainage. As some studies showed that pleural pressure monitoring might be associated with significant advantages, pleural manome...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,评审

    doi：10.1016/j.rmed.2018.01.014

    authors： Grabczak EM,Krenke R,Zielinska-Krawczyk M,Light RW

    更新日期：2018-12-01 00:00:00

  • A randomized, double-blind dose-ranging study of the novel LAMA GSK573719 in patients with COPD.

    abstract：BACKGROUND:This study evaluated the dose-response and dosing interval of the novel long-acting muscarinic receptor antagonist (LAMA) GSK573719 in patients with COPD. METHODS:This randomized, double-blind, placebo-controlled, 3-way cross-over, incomplete block study evaluated 5 once-daily doses of GSK573719 (62.5-1000 ...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.rmed.2012.03.012

    authors： Donohue JF,Anzueto A,Brooks J,Mehta R,Kalberg C,Crater G

    更新日期：2012-07-01 00:00:00

  • Lower airway bacterial colonization in asymptomatic smokers and smokers with chronic bronchitis and recurrent exacerbations.

    abstract：:Bacterial colonization of the lower airways in patients with chronic bronchitis (CB) has been described mainly in patients with co-existing chronic obstructive pulmonary disease (COPD). Although smoking has been identified as a risk factor for bacterial colonization it is not known whether asymptomatic smokers (AS) ca...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1053/rmed.2000.0857

    authors： Qvarfordt I,Riise GC,Andersson BA,Larsson S

    更新日期：2000-09-01 00:00:00

  • Comparative study of two different modes of noninvasive home mechanical ventilation in chronic respiratory failure.

    abstract：STUDY OBJECTIVE:Two modes of noninvasive home mechanical ventilation (NIHMV) with volumetric ventilators were compared in patients with chronic respiratory failure. DESIGN:Retrospective, parallel-group, comparative study. SETTING:Third-level teaching Hospital in Barcelona (Spain). PATIENTS AND METHODS:We studied 110...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2005.08.008

    authors： Muñoz X,Crespo A,Marti S,Torres F,Ferrer J,Morell F

    更新日期：2006-04-01 00:00:00

  • Airway inflammation in obstructive sleep apnea: is leptin the missing link?

    abstract：BACKGROUND:Local and systemic inflammation is implicated in the pathophysiology of Obstructive Sleep Apnea (OSA). Exhaled breath condensate (EBC) is a non-invasive sampling method for the lower airways. However, it is important to consider the potential effect of the systemic origin whereas systemic inflammation is sig...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2008.04.021

    authors： Antonopoulou S,Loukides S,Papatheodorou G,Roussos C,Alchanatis M

    更新日期：2008-10-01 00:00:00

  • Tumor necrosis factor-alpha serum levels, weight loss and tissue oxygenation in chronic obstructive pulmonary disease.

    abstract：:Weight loss has been recognized as a feature of advanced emphysema and a factor of poor prognosis, but its mechanisms remain obscure. Studies have demonstrated high serum concentrations of TNF-a (cachexin) in chronic obstructive pulmonary disease (COPD) patients with emphysema. Pink puffers (PP) COPD patients have wor...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1053/rmed.2002.1322

    authors： Pitsiou G,Kyriazis G,Hatzizisi O,Argyropoulou P,Mavrofridis E,Patakas D

    更新日期：2002-08-01 00:00:00

  • Severe vocal cord dysfunction resistant to all current therapeutic interventions.

    abstract：:Vocal cord dysfunction (VCD) is characterised by paradoxical vocal cord adduction during inspiration or throughout the respiratory cycle, it results in wheeze, stridor, cough and dyspnoea. Although asthma and VCD can coexist, patients with VCD are frequently misdiagnosed with refractory asthma. It can severely restric...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2006.08.009

    authors： Goldstein R,Bright J,Jones SM,Niven RM

    更新日期：2007-04-01 00:00:00

  • Lactate dehydrogenase as prognostic factor in limited and extensive disease stage small cell lung cancer - a retrospective single institution analysis.

    abstract：PURPOSE:The aim of this retrospective study is to present data on clinical significance of lactate dehydrogenase (LDH) serum levels in an unselected contemporary patient population with small cell lung cancer (SCLC) in limited disease (LD) and extensive disease stage (ED). PATIENTS AND METHODS:From June 2004 to June 2...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2010.07.013

    authors： Hermes A,Gatzemeier U,Waschki B,Reck M

    更新日期：2010-12-01 00:00:00

  • Self-reported sleepiness while driving as a risk factor for traffic accidents in patients with obstructive sleep apnoea syndrome and in non-apnoeic snorers.

    abstract：:The obstructive sleep apnoea syndrome (OSAS) is a condition causing daytime sleepiness and has been related to an increased risk for traffic accidents. However, the evidence linking severity of OSAS to a higher rate of automobile crashes is based on limited data. The aims of this study were to study the traffic accide...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1053/rmed.2000.0869

    authors： Lloberes P,Levy G,Descals C,Sampol G,Roca A,Sagales T,de la Calzada MD

    更新日期：2000-10-01 00:00:00

  • Omalizumab-induced decrease of FcξRI expression in patients with severe allergic asthma.

    abstract：BACKGROUND:It is documented that omalizumab treatment reduces the cell surface expression of immunoglobulin E high-affinity receptor (FcɛRI) on several cell types. This has not been investigated in patients with uncontrolled severe persistent allergic asthma. METHODS:In a double-blind, randomized, placebo-controlled s...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.rmed.2010.07.011

    authors： Chanez P,Contin-Bordes C,Garcia G,Verkindre C,Didier A,De Blay F,de Lara MT,Blanco P,Moreau JF,Robinson P,Bourdeix I,Trunet P,Le Gros V,Humbert M,Molimard M

    更新日期：2010-11-01 00:00:00

  • Association between all-cause and cause-specific mortality and the GOLD stages 1-4: A 30-year follow-up among Finnish adults.

    abstract：BACKGROUND:Mortality correlates with the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria of airway obstruction. Yet, little data exist concerning the long-term survival of patients presenting with different levels of obstruction. METHODS:We studied the association between all-cause and cause-spe...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.rmed.2015.06.002

    authors： Mattila T,Vasankari T,Kanervisto M,Laitinen T,Impivaara O,Rissanen H,Knekt P,Jousilahti P,Saarelainen S,Puukka P,Heliövaara M

    更新日期：2015-08-01 00:00:00

  • A single high dose of formoterol is as effective as the same dose administered in a cumulative manner in patients with acute exacerbation of COPD.

    abstract：:Several clinical trials have shown that the inhaled beta2-agonists with long-acting properties, formoterol and salmeterol, may be effective in acute exacerbations of chronic obstructive pulmonary disease (COPD). However, there is a great deal of controversy regarding the timing and optimal dose of inhaled beta2-agonis...

    journal_title：Respiratory medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1053/rmed.2002.1456

    authors： Cazzola M,Santus P,Matera MG,Carlucci P,Belloli E,Di Marco F,Centanni S

    更新日期：2003-05-01 00:00:00

  • Low prevalence of pulmonary involvement in children with inflammatory bowel disease.

    abstract：BACKGROUND:Since extraintestinal sites of inflammation have been demonstrated in patients with Crohn's disease (CD) and ulcerative colitis (UC), both entities are regarded as systemic disorders. There are only scarce data on the prevalence of inflammatory bowel disease (IBD)-associated lung involvement in children. OB...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2012.03.005

    authors： Peradzyńska J,Krenke K,Lange J,Banaszkiewicz A,Łazowska-Przeorek I,Radzikowski A,Kulus M

    更新日期：2012-07-01 00:00:00

  • The relationship between indicators of building dampness and respiratory health in young Swedish adults.

    abstract：:Several epidemiological studies have indicated that building dampness affects the respiratory health of the inhabitants. In this study we investigated the relationship between building dampness and respiratory symptoms in young Swedish adults. In 1993, as a part of the European Community Respiratory Health Survey stag...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1053/rmed.2002.1389

    authors： Gunnbjörnsdottir MI,Norbäck D,Plaschke P,Norrman E,Björnsson E,Janson C

    更新日期：2003-04-01 00:00:00

  • Prevalence of work-related symptoms and serum-specific antibodies to wheat flour in exposed workers in the bakery industry.

    abstract：BACKGROUND:Although baker's asthma (BA) is a common occupational asthma, there have been few reports on this disease in Korean subjects. OBJECTIVES:We evaluated the prevalence of serum-specific IgE, IgG1, and IgG4 antibodies in relation to work-related respiratory symptoms in a single industrial bakery. METHODS:Three...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2007.11.015

    authors： Hur GY,Koh DH,Kim HA,Park HJ,Ye YM,Kim KS,Park HS

    更新日期：2008-04-01 00:00:00