Abstract:
BACKGROUND:In studies of idiopathic pulmonary fibrosis (IPF), whites makeup the vast majority of subjects. Whether ethnic/racial differences in idiopathic pulmonary fibrosis occur in the general population is unknown. METHODS:To compare the presence of IPF between ethnic/racial groups of U.S. decedents from 1989 to 2007 by using the National Center for Health Statistics database. RESULTS:There were 251,058 U.S. decedents with IPF; 87.2% were non-Hispanic whites (White), 5.1% were non-Hispanic African American (black), 5.4% were Hispanic, and 2.2% were from other ethnic/racial groups (other). Whites coded with IPF died older than those in the other groups (77.9 years vs. 72.1 years for blacks, 75.3 years for Hispanics, and 75.6 years for others; p < 0.0001 for all pairwise comparisons). When controlling for age and for sex, compared with whites, both Hispanics and Others were more likely to be coded with IPF (OR = 1.47, 95% CI 1.44-1.49, p < 0.0001 and OR = 1.29, 95% CI 1.26-1.36, p < 0.0001 respectively), while blacks were significantly less likely to be coded with IPF (OR = 0.48, 95% CI 0.47-0.49, p < 0.0001). Among decedents with IPF, Hispanics were more likely, and blacks were less likely, than whites to die from IPF (OR = 1.24, 95% CI 1.20-1.29, p < 0.0001 and OR = 0.91, 95% CI 0.87-0.94, p < 0.0001). CONCLUSION:From 1989 to 2007, black decedents were less-and Hispanics were more-likely than whites to die of/with IPF. Research is needed to determine if genetic differences between ethnic/racial groups explain these findings.
journal_name
Respir Medjournal_title
Respiratory medicineauthors
Swigris JJ,Olson AL,Huie TJ,Fernandez-Perez ER,Solomon J,Sprunger D,Brown KKdoi
10.1016/j.rmed.2012.01.002subject
Has Abstractpub_date
2012-04-01 00:00:00pages
588-93issue
4eissn
0954-6111issn
1532-3064pii
S0954-6111(12)00034-0journal_volume
106pub_type
杂志文章abstract::Although the principles of asthma management are well established in Europe, the available data indicate that asthma in patients is not well controlled. Many patients derive incomplete benefit from their inhaled medication because they do not use inhaler devices correctly and this may compromise asthma control. The Ae...
journal_title:Respiratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.rmed.2006.01.008
更新日期:2006-09-01 00:00:00
abstract:UNLABELLED:We report bronchoscopic changes observed in children with recurrent lower airways infections (RLAI) and findings in control children undergoing bronchoscopy for causes other than RLAI. PATIENTS AND METHODS:Retrospective case-control cohorts study. The clinical records of children who had fiberoptic bronchos...
journal_title:Respiratory medicine
pub_type: 杂志文章
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abstract::Inhalation of on-demand salbutamol (ODS) several times daily is sometimes the only beta2-agonist prescribed in moderate persistent asthma, whereas a long-acting beta2-agonist should be added. This trial aimed to compare the efficacy of formoterol dry-powder capsule 12 microg b.i.d. (Foradil) and ODS in patients with m...
journal_title:Respiratory medicine
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1053/rmed.2000.0972
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Slovenia is one of the few countries where IS6110 RFLP is applied for genotyping M. tuberculosis at a nationwide level, which has been in effect since 2000. Based on S6110 RFLP clustering, typical risk factors and routes of M. tuberculosis transmission were identified, such as alcohol abuse, homelessness, an...
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abstract:BACKGROUND:The 6 min walk test (6MWT) provides prognostic information in various respiratory diseases, but limited data exist in cystic fibrosis (CF) adults. METHODS:Consecutive CF adults who performed 6MWT at Cochin Hospital (Paris, France) over 12 years were analyzed. The cut-off 6 min walking distance (6MWD) value ...
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/j.rmed.2004.08.003
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abstract:BACKGROUND:Non-invasive ventilation and exercise training might prove beneficial in the management of COPD patients. OBJETIVE:to compare the combined use of exercise training and non-invasive ventilation with the two interventions separately in chronic respiratory failure due to chronic obstructive pulmonary disease. ...
journal_title:Respiratory medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.rmed.2014.10.005
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Spirometry data predict mortality, but are less sensitive to detect dysfunction in small airways as compared to the slope of phase III (the N2 slope) of the single breath nitrogen test. The association between the N2 slope and mortality has been studied with conflicting results. In the present study the prog...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2016.01.002
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journal_title:Respiratory medicine
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1990-09-01 00:00:00
abstract:BACKGROUND:Exhaled breath condensate (EBC) is simple to collect and as such a non-invasive method that has attracted substantial interest in the last few years. However, several methodological concerns have been raised and it has been difficult to reproduce results between different centres. Because of low concentratio...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2005.04.007
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abstract::Long-acting bronchodilators in combination with inhaled corticosteroids (ICS) are recommended to decrease the risk of recurrent exacerbations in patients with Global initiative for chronic Obstructive Lung Disease (GOLD) stage 3-4 chronic obstructive pulmonary disease (COPD). There is increasing concern about the clin...
journal_title:Respiratory medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.rmed.2014.01.002
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVES:To identify factors associated with late recovery (≥ 8 days from exacerbation start) in patients with acute exacerbations of chronic bronchitis/COPD (AECB/AECOPD). METHODS:An international, observational, non-interventional study in outpatients with AECB/AECOPD who received treatment for their exacerbation ...
journal_title:Respiratory medicine
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.rmed.2012.06.002
更新日期:2012-09-01 00:00:00
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journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2007.04.001
更新日期:2007-09-01 00:00:00
abstract::Primary ciliary dyskinesia (PCD) is a genetic condition resulting in bronchiectasis. Exhaled gas nitric oxide (FE(NO)) is reduced in PCD. A model of pulmonary NO exchange dynamics can be used to demonstrate relative contributions of bronchial (J'aw(NO)) and peripheral airway (Calv(NO)) NO to the final FE(NO) concentra...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2008.12.004
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:This study investigated the accuracy of impulse oscillometry (IOS) combined with fractional exhaled nitric oxide (FeNO) to assess asthma control among preschool children. METHODS:A total of 79 preschool children(3-6 year old) with asthma and 25 healthy preschool children who visited a paediatrician were enro...
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pub_type: 杂志文章
doi:10.1016/j.rmed.2018.10.009
更新日期:2018-12-01 00:00:00
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journal_title:Respiratory medicine
pub_type: 信件
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更新日期:2016-11-01 00:00:00
abstract:INTRODUCTION:Chronic obstructive pulmonary disease (COPD) is a common respiratory condition and the fourth leading cause of death in Canada. However, little is known about the impact of COPD on the lives and attitudes of individuals living with this condition. The purpose of this study was to determine whether Canadian...
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pub_type: 杂志文章
doi:10.1016/j.rmed.2009.01.018
更新日期:2009-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.rmed.2020.106146
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abstract:BACKGROUND:Cystic Fibrosis (CF) is the most common life limiting genetic disorder, characterized by chronic respiratory failure secondary to inflammation and chronic bacterial lung infection. Pseudomonas aeruginosa lung infection is associated with more severe lung disease and rapid progression of respiratory failure w...
journal_title:Respiratory medicine
pub_type: 杂志文章
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journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/s0954-6111(96)90148-1
更新日期:1996-10-01 00:00:00
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journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2004.09.001
更新日期:2005-04-01 00:00:00
abstract::Totally implantable venous intravenous access devices (TIVADs) have an essential role in the frequent delivery of antibiotics in cystic fibrosis (CF) patients. This study at the Royal Brompton Hospital (RBH) reports the experience of TIVADs in patients attending the RBH adult CF unit implanted at the RBH and elsewhere...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1053/rmed.2000.0943
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND:Combination therapy with inhaled corticosteroids (ICS) and long-acting β(2)-adrenergic agonists (LABA) is reported to have superior effects on controlling asthma symptoms to ICS alone; however, there is no molecular-based evidence to explain the clinical effects. Here, the effect of the ICS/LABA combination ...
journal_title:Respiratory medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.rmed.2011.08.020
更新日期:2011-12-01 00:00:00
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journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1053/rmed.2000.0797
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:Apoptosis is thought to play an important role in the development of acute respiratory distress syndrome (ARDS). We evaluated the bronchoalveolar lavage (BAL) fluid from ARDS patients focusing on apoptosis. METHODS:The study enrolled 31 ARDS patients and 20 healthy controls. BAL fluid levels of caspase-clea...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2007.10.001
更新日期:2008-03-01 00:00:00
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journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2003.10.009
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:Inappropriate use of short-acting beta-agonists (SABA) has been associated with increased morbidity and mortality in asthma. However, the extent and pattern of SABA use have changed significantly over recent years. The outcomes in patients who are contemporarily receiving inappropriate doses of SABA have not...
journal_title:Respiratory medicine
pub_type: 杂志文章
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更新日期:2017-10-01 00:00:00
abstract:AIMS:This study tested inhibitory effects of in vitro Montelukast treatment on nasal airway epithelial cells (AEC) cultured from asthmatic patients treated with Montelukast with and without concomitant allergic rhinitis. We further examined the effect of Montelukast withdrawal in these patients on cytokine release from...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2013.09.006
更新日期:2013-12-01 00:00:00
abstract::Gastroesophageal reflux (GER) may induce respiratory symptoms (RS) through inhalation of acid gastric contents. To characterize the airway inflammation associated with this condition, 20 children [7.4 (0.9) yr old] with "difficult to treat" RS and a positive 24-h oesophageal pH monitoring (pHm) were studied and bronch...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2005.05.011
更新日期:2006-02-01 00:00:00
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journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2009.01.011
更新日期:2009-07-01 00:00:00