Alpha 1-antitrypsin deficiency and infantile liver disease.

abstract：AIMS:To establish whether subjects with previous evidence of sleep apnoea prior to adenotonsillectomy continue to have evidence of narrower upper airways during sleep, 12 years later. METHODS:Twenty subjects (median age 16 years) underwent repeat sleep studies at home, 12 years after such studies had shown significant...

journal_title：Archives of disease in childhood

authors： Tasker C,Crosby JH,Stradling JR

更新日期：2002-01-01 00:00:00

abstract：:Four preterm infants of very low birthweight (less than 1500 g) developed signs of copper deficiency between age 8 and 10 weeks. All had required prolonged ventilatory support, parenteral nutrition, and nasojejunal feeding. The clinical features, which included osteoporosis, oedema, anaemia, neutropenia, and late apno...

journal_title：Archives of disease in childhood

authors： Sutton AM,Harvie A,Cockburn F,Farquharson J,Logan RW

更新日期：1985-07-01 00:00:00

abstract：:We have studied 50 children with one parent with asthma at a mean age of 6.4 years by symptom questionnaire and performed allergy skin testing and measurement of bronchial responsiveness to methacholine in both parent and child in 29-32 cases. Ninety eight per cent of the parents were receiving medication for asthma. ...

journal_title：Archives of disease in childhood

authors： Clifford RD,Pugsley A,Radford M,Holgate ST

更新日期：1987-01-01 00:00:00

abstract：:We report a child who presented with a progressive neurological disorder associated with hypertension and paroxysms of irritability and sweating in whom an abnormality of catecholamine metabolism or excretion was demonstrated. An elder sister died at the age of 2 1/2 years with similar clinical symptoms but without bl...

journal_title：Archives of disease in childhood

authors： Young I,Hosking GP

更新日期：1978-08-01 00:00:00

abstract：:1 case study and a clinical study with laboratory rats examined the question of breast milk jaundice. The case study confirmed clinical diagnosis of breast milk jaundice. The clinical study compared the effects of breast milk and 3alpha, 20beta-pregnanediol on the conjugation of bilirubin and o-aminophenol by rat li...

journal_title：Archives of disease in childhood

authors： Hargreaves T,Piper RF

更新日期：1971-04-01 00:00:00

abstract：:Fifty nine children of short stature exercised for 10 minutes on a non-motorised treadmill. In 49 a growth hormone concentration of greater than 15 mU/l was reached, effectively excluding growth hormone deficiency. In 10 children the growth hormone concentration failed to reach 15 mU/l; growth hormone deficiency was c...

journal_title：Archives of disease in childhood

authors： de San Lazaro C,Parkin JM,Turner SJ

更新日期：1984-12-01 00:00:00

abstract：:The role of budesonide in controlling chest symptoms in infants was assessed. It was administered from a metered dose inhaler into a large volume spacer (Nebuhaler) with attached Laerdal mask. Twenty nine infants were recruited into a double blind crossover trial. Five defaulted. The remaining 24 (mean age 11 months) ...

journal_title：Archives of disease in childhood

authors： Noble V,Ruggins NR,Everard ML,Milner AD

更新日期：1992-03-01 00:00:00

abstract：:The National Grid is a training scheme that represents a unique partnership between Deaneries and the Royal College of Paediatrics and Child Health (RCPCH) in offering through national competition, equitable access to high quality subspecialty training. Paediatrics is unusual in that within the umbrella Certificate of...

journal_title：Archives of disease in childhood

authors： McGraw M,Ng G

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Our current understanding regarding the aetiology of infantile acute liver failure largely derives from studies conducted by regional liver units. This may introduce selection bias and therefore not provide a true reflection of the wider population. METHODS:Every coagulation screen with a prothrombin time ≥...

journal_title：Archives of disease in childhood

authors： Wands D,Tayler R,Kelly D,Pinto F,Simpson JH,Hansen R

更新日期：2020-08-01 00:00:00

abstract：:Pethidine or an epidural injection of bupivacaine are common forms of obstetric analgesia in Britain. Bupivacaine has been thought to have little effect on the fetus, but neurobehavioural studies have cast doubt on this. We therefore investigated the elimination of these drugs by babies in similar population groups. B...

journal_title：Archives of disease in childhood

authors： Cooper LV,Stephen GW,Aggett PJ

更新日期：1977-08-01 00:00:00

abstract：OBJECTIVES:To determine the effectiveness of auditory integration training (AIT) or other methods of sound therapy in people with autism spectrum disorders (ASD). STUDY DESIGN:A systematic review was carried out of randomised controlled trials (RCTs) of adults or children with ASD. Meta-analysis was attempted. RESULT...

journal_title：Archives of disease in childhood

authors： Sinha Y,Silove N,Wheeler D,Williams K

更新日期：2006-12-01 00:00:00

abstract：:Social inequalities in a variety of indicators of child health were measured using a 'small area' geographical method of social classification. Cross sectional analyses of routine child health information and of a population survey of the height of primary school children were used. Social classification was by census...

journal_title：Archives of disease in childhood

authors： Reading R,Jarvis S,Openshaw S

更新日期：1993-05-01 00:00:00

abstract：:A 6-week-old girl with fever, hypernatraemia, dehydration, and polyuria failed to concentrate urine in response to exogenous vasopressin administration. There was no family history of nephrogenic diabetes insipidus. When she was 15 months old, the infusion of vasopressin did not produce an increase in urinary cyclic-A...

journal_title：Archives of disease in childhood

authors： Schreiner RL,Skafish PR,Anand SK,Northway JD

更新日期：1978-11-01 00:00:00

abstract：:Diabetic control in 88 children attending three general paediatric clinics was compared prospectively over one year with that of 89 children attending a specialist paediatric diabetic clinic. Glycated haemoglobin (HbA1) concentration and days admitted were significantly lower in the group attending the specialist clin...

journal_title：Archives of disease in childhood

authors： Bloomfield S,Farquhar JW

更新日期：1990-01-01 00:00:00

abstract：:Two newborn infants, male (A) and female (B), with lethal hyperammonaemia are described in the same family. In both, symptoms started on the second day of life. Lethargy and hypotonia were the most prominent initial findings and were followed by convulsions and coma. In both, blood ammonia levels rose to 570 mumol/u (...

journal_title：Archives of disease in childhood

authors： Mantagos S,Tsagaraki S,Burgess EA,Oberholzer V,Palmer T,Sacks J,Baibas S,Valaes T

更新日期：1978-03-01 00:00:00

abstract：:The communication development in 11 children with Angelman's syndrome is described. The clinical observation that these children appear to have a greater ability with receptive rather than expressive language is investigated and these skills assessed using published communication schedules. In addition the understandi...

journal_title：Archives of disease in childhood

authors： Jolleff N,Ryan MM

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVES:To understand the experiences and perceptions of healthcare services of children with life-limiting and life-threatening conditions and their family members, including palliative care. DESIGN:Longitudinal qualitative interview study with children and their family members. Up to three in-depth interviews wer...

journal_title：Archives of disease in childhood

authors： Mitchell S,Slowther AM,Coad J,Dale J

更新日期：2020-11-16 00:00:00

abstract：:Children with cystic fibrosis have variable degrees of exocrine pancreatic insufficiency which, if untreated, is the main cause of fat malabsorption. The impact of pancreatic enzyme supplementation on fat digestion was measured in 41 children with cystic fibrosis, 11 healthy controls, and five children with mucosal di...

journal_title：Archives of disease in childhood

authors： Amarri S,Harding M,Coward WA,Evans TJ,Weaver LT

更新日期：1997-04-01 00:00:00

abstract：:Fifteen per cent of children treated with growth hormone (GH) are receiving treatment for Turner syndrome, but few results are available on final height in the UK. In this study, data were obtained from the UK KIGS database for 485 girls with Turner syndrome who were treated from 1986, allowing an audit of practice an...

journal_title：Archives of disease in childhood

authors： Betts PR,Butler GE,Donaldson MD,Dunger DB,Johnston DI,Kelnar CJ,Kirk J,Price DA,Wilton P

更新日期：1999-03-01 00:00:00

abstract：:The provision of positive end expiratory pressure, via a unique portable system, in the long term management of a child with thoracic dystrophy is reported. The system uses low gas flow enabling a reduction in equipment and simplification of the circuit as compared with a standard continuous positive airways pressure ...

journal_title：Archives of disease in childhood

authors： Edees S,Moulden A,Winter RJ

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To determine risk factors for childhood overweight that can be identified during the first year of life to facilitate early identification and targeted intervention. DESIGN:Systematic review and meta-analysis. SEARCH STRATEGY:Electronic database search of MEDLINE, EMBASE, PubMed and CAB Abstracts. ELIGIBIL...

journal_title：Archives of disease in childhood

authors： Weng SF,Redsell SA,Swift JA,Yang M,Glazebrook CP

更新日期：2012-12-01 00:00:00

abstract：:Two hundred and twenty eight deprived children were compared with a matched sample of more endowed children living in the same urban area. Both groups were served by the same experienced primary health care team. The deprived group had a significantly higher number of general practitioner consultations and admissions ...

journal_title：Archives of disease in childhood

authors： Marsh GN,Channing DM

更新日期：1987-04-01 00:00:00

abstract：OBJECTIVE:To investigate possible renal toxicity of long-term gentamicin inhalation in patients with cystic fibrosis. METHODS:Urinary N-acetyl-beta-D-glucosaminidase (NAG) activity was measured during routine respiratory clinic visits. Outpatient records were reviewed for data on long-term gentamicin inhalation, and p...

journal_title：Archives of disease in childhood

authors： Ring E,Eber E,Erwa W,Zach MS

更新日期：1998-06-01 00:00:00

abstract：:The introduction of enteric coated pancreatic enzyme supplements in the early 1980s was undoubtedly one of the major advances in the care of children with cystic fibrosis. Further refinements in the presentation of these preparations inevitably followed, to improve patient acceptability and compliance. The emergence o...

journal_title：Archives of disease in childhood

authors： Smyth RL

更新日期：1996-05-01 00:00:00

abstract：:Urinary tract anomalies were prospectively investigated with ultrasound in 29 children with functional constipation. These children were compared before and after treatment with 451 age matched healthy controls without constipation. The bladder residue and upper renal tract dilatation after micturition were significan...

journal_title：Archives of disease in childhood

authors： Dohil R,Roberts E,Jones KV,Jenkins HR

更新日期：1994-01-01 00:00:00

abstract：:A family with multiple congenital scalp defects, over two generations and probably genetically determined, is described. Although alarming in appearance, surgical intervention is not indicated at least for small lesions. The risk of haemorrhage and meningitis is emphasized. ...

journal_title：Archives of disease in childhood

authors： Lassman LP,Sims DG

更新日期：1975-12-01 00:00:00

abstract：:The lungs of 482 liveborn infants were examined at necropsy for the presence of intravascular lipid. Forty one patients had received parenteral feeding (including lipid emulsion in 30), and 441 had died before starting feeds or had received enteral feeds alone. Tissue was processed into wax and then stained with Sudan...

journal_title：Archives of disease in childhood

authors： Puntis JW,Rushton DI

更新日期：1991-01-01 00:00:00

abstract：:Six families with at least one infant each with confirmed ornithine transcarbamylase deficiency were investigated by DNA analysis. All the affected sons had died, and no DNA had been stored. Using the restriction endonucleases MspI and Bam HI three restriction fragment length polymorphisms were detected which led to e...

journal_title：Archives of disease in childhood

authors： Svirklys LG,Wilcken B,Hammond J,Mackinlay AG,O'Sullivan WJ

更新日期：1988-03-01 00:00:00

abstract：:A 5.7 year old boy with alpha 1-antitrypsin deficiency developed intractable ascites after liver transplantation. Conservative treatment was unsuccessful and after 18 days concentrated ascitic fluid was reinfused intravenously using a Gambro haemofilter. The ascitic loss resolved rapidly. This new method of ultrafiltr...

journal_title：Archives of disease in childhood

authors： Noble-Jamieson G,Jamieson N,Barnes ND

更新日期：1991-08-01 00:00:00

abstract：:Cotton wool balls have been used to aid the collection of urine from infants. Concentrations of two urinary proteins, albumin and retinol binding protein, decreased by 40 and 80% respectively within 15 minutes of contact with the cotton wool. Cotton wool balls should not be used when investigating proteinuria. ...

journal_title：Archives of disease in childhood

authors： Smith GC,Taylor CM

更新日期：1992-12-01 00:00:00