Abstract：
AIMS:To establish whether subjects with previous evidence of sleep apnoea prior to adenotonsillectomy continue to have evidence of narrower upper airways during sleep, 12 years later. METHODS:Twenty subjects (median age 16 years) underwent repeat sleep studies at home, 12 years after such studies had shown significant sleep apnoea in many of them prior to an adenotonsillectomy. Twenty control subjects, also studied 12 years ago, underwent repeat home sleep studies as well. The sleep studies provided information on snoring, hypoxia, and inspiratory effort (from measures of pulse transit time). A questionnaire was also administered, the subjects were weighed, and their heights measured. RESULTS:There was more reported snoring in the previous adenotonsillectomy group (50% versus 20%) and also during the sleep study (80 versus 31 snores per hour). The measure of inspiratory effort overnight was higher in the previous adenotonsillectomy group (15.6 versus 12.3 ms). Allowance for potentially confounding variables (obesity and nasal congestion) partially reduced the statistical significance of the difference in snoring, but not that of the measure of inspiratory effort. CONCLUSION:Results suggest that a narrower upper airway during sleep, to the point of snoring, persists 12 years after adenotonsillectomy, and may partly account for the occurrence earlier of preoperative sleep apnoea while adenotonsillar hypertrophy was present. It is not known if this narrowing is one of the risk factors for later development of adult sleep apnoea.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Tasker C,Crosby JH,Stradling JRdoi
10.1136/adc.86.1.34subject
Has Abstractpub_date
2002-01-01 00:00:00pages
34-7issue
1eissn
0003-9888issn
1468-2044journal_volume
86pub_type
杂志文章abstract：:Cystic fibrosis is a disease that still causes a reduced life expectancy. The treatment burden remains high for affected individuals with often a combination of multiple oral and inhaled medications, as well as physiotherapy, required on a daily basis. In this article, we look at an overview of the pathogenesis, how t...
journal_title：Archives of disease in childhood
pub_type： 杂志文章,评审
doi：10.1136/archdischild-2013-304400
更新日期：2014-11-01 00:00:00
abstract：:The relation between intraventricular haemorrhage (IVH) and hyaline membrane disease (HMD) was studied in singletons that came to necropsy at Hammersmith Hospital over the years 1966-73. The incidence of IVH in singleton live births was 3-22/1000 and of HMD 4-44/1000. Although the high figures were partily due to the ...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.51.10.755
更新日期：1976-10-01 00:00:00
abstract：AIMS:To determine the prevalence of hypovitaminosis D among healthy adolescent schoolgirls attending an inner city multiethnic girls' school. METHODS:Fifty one (28%) of 182 girls (14 white, 37 non-white; median age 15.3 years, range 14.7-16.6) took part in the study. Biochemical parameters, dietary vitamin D intake, m...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.2005.077974
更新日期：2006-07-01 00:00:00
abstract：:Two male patients with congenital cleft lip and palate first seen at ages 10.2 and 21.5 years presented with typical signs of hypothalamic-interior pituitary hormone deficiencies. They were found to lack GH, LH, and FSH and to be partially deficient in TSH and ACTH. Several congenital defects may explain this rare syn...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.53.12.952
更新日期：1978-12-01 00:00:00
abstract：:Imaging has many uses, but in cases of suspected child abuse, radiographs and CT scans are vital in identifying fractures and head injury that may not be clinically obvious. There are growing concerns about the small but potential adverse effects of radiation, including cancer, in the paediatric population as a result...
journal_title：Archives of disease in childhood
pub_type： 杂志文章,评审
doi：10.1136/archdischild-2015-308418
更新日期：2015-12-01 00:00:00
abstract：:Ketamine hydrochloride 2 mg/kg, together with atropine 0.2 mg, has been given intravenously on 100 occasions on a general paediatric ward. No serious side effects occurred. Dreams followed in 4 children but did not reduce acceptability of the drug. In our hands it has greatly reduced the pain and distress of children ...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.51.1.56
更新日期：1976-01-01 00:00:00
abstract：:Pulmonary veno-occlusive disease is a rare form of primary pulmonary hypertension of unknown aetiology. Four cases were diagnosed in young patients. The diagnosis was suspected on the basis of clinical, radiological, echocardiographic, and catheter evidence and confirmed by taking a lung biopsy sample. In all patients...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.68.1.97
更新日期：1993-01-01 00:00:00
abstract：:Early postnatal malnutrition produces delay in growth and developmental processes, and children from a low socioeconomical level where undernutrition is prevalent are shorter than those from higher socioeconomic levels. We examined the effects of severe and early protein energy malnutrition on growth and bone maturati...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.61.3.257
更新日期：1986-03-01 00:00:00
abstract：:The allergic response is distinct from other immune reactions in its reliance on IgE, its high affinity receptor, Fc epsilon RI, and the primary effector cell--the tissue mast cell. Positive skin tests or raised concentrations of specific immunoglobulin E (IgE) in the serum define IgE sensitisation or "atopy". IgE par...
journal_title：Archives of disease in childhood
pub_type： 杂志文章,评审
doi：10.1136/adc.88.1.71
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:To assess height and body mass index standard deviation scores up to 20 years after treatment for acute lymphoblastic leukaemia (ALL). SUBJECTS AND METHODS:Height and body mass index standard deviation scores were measured in 33 patients (14 boys and 19 girls) with childhood ALL at diagnosis, after the end o...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.79.2.161
更新日期：1998-08-01 00:00:00
abstract：:The role of disseminated intravascular clotting (DIC) in the pathogenesis of the bleeding diathesis kwashiorkor was investigated in 22 patients. According to the severity of the clinical and haematological findings, two grades of DIC were observed. A severe grade of DIC was shown in 6 cases (5 fatal) presenting with ...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.50.4.308
更新日期：1975-04-01 00:00:00
abstract：:A 32-day-old male infant had hypocalcaemic convulsions associated with asymptomatic maternal hyperparathyroidism. Very low total and ionised serum calcium, increased serum phosphate, and normal serum parathyroid hormone (PTH) and 25-hydroxycholecalciferol (25-OHD3) concentrations were found at admission. After treatme...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.53.4.308
更新日期：1978-04-01 00:00:00
abstract：:Fulminant endocarditis affecting the mitral valve in an 11-year-old boy was caused by a nontoxogenic strain of Corynebacterium diphtheriae. ...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.51.3.227
更新日期：1976-03-01 00:00:00
abstract：:A neonate developed complete thrombosis of the abdominal aorta after catheterisation of the umbilical artery. This was successfully treated with an intravenous infusion of streptokinase. ...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.63.9.1086
更新日期：1988-09-01 00:00:00
abstract：:Five cases are reported of spontaneous remission of chronic childhood thrombocytopenia four or more years after diagnosis. Other than typical features of chronic idiopathic thrombocytopenic purpura there were no obvious markers predictive of late remission, although a slow progressive recovery was common to four of th...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.68.5.680
更新日期：1993-05-01 00:00:00
abstract：:We studied 91 offspring of ABO incompatible preganacies and 30 controls resulting from O--O pregnancies to test whether cord bilirubin levels could be used to predict the severity of hyperbilirubinaemia in ABO incompatibility. Blood group, direct Coombs's test, and serum bilirubin estimations were carried out on cord ...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.52.3.219
更新日期：1977-03-01 00:00:00
abstract：:The accuracies of chromogenic agar and the GeneXpert real-time PCR system (Cepheid, Sunnyvale, California, USA) for admission methicillin-resistant Staphylococcus aureus (MRSA) screening of 1336 consecutive paediatric intensive care unit patients (1282 evaluable swab results) were determined using enrichment culture a...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.2010.185785
更新日期：2012-03-01 00:00:00
abstract：:The introduction of chemoprophylaxis with rifampicin and isoniazid in 1981 significantly reduced the incidence of tuberculosis. Between 1978 and 1981 children accounted for 136 of 642 notified cases, and this was reduced to 55 of 418 between 1982 and 1986. This effect was most obvious among children from the Indian su...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.62.10.1005
更新日期：1987-10-01 00:00:00
abstract：:An 11 year old boy presented with severe acute hereditary coproporphyria. Despite supportive measures his condition deteriorated after admission. Haem arginate, started two days after presentation, produced appreciable inhibition of porphyrin precursor overproduction and clinical improvement. ...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.66.6.730
更新日期：1991-06-01 00:00:00
abstract：:In a newborn baby, suffering from persistent severe hypoglycaemia with convulsions glucagon deficiency was shown. Treatment with zinc-protamine-glucagon injection twice daily resulted in normal blood glucose levels. Motor development is delayed. ...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.53.5.422
更新日期：1978-05-01 00:00:00
abstract：:In 100 patients with cystic fibrosis the severity of steatorrhoea was assessed by three separate methods. Using chemical faecal fat assay as the gold standard, two other rapid and inexpensive methods were compared with it. The steatocrit method proved unreliable in our hands and gave little indication of the presence ...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.65.1.99
更新日期：1990-01-01 00:00:00
abstract：:Chromatographic analysis of sugars in the stools of 40 normal newborn infants has shown the presence of an oligosaccharide in 85% of samples. The oligosaccharide has been shown to contain fucose (6-deoxygalactose), glucose, and galactose and is present in normal breast milk. In addition fucose has also been found in t...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.53.11.913
更新日期：1978-11-01 00:00:00
abstract：:The numbers of children under 5 years in South Glamorgan admitted to hospital because of accidental poisoning have been analysed for 1980-4. There has been no significant fall in those taking solid dose, prescribable medications since the voluntary agreement between the government and the pharmaceutical profession in ...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.60.12.1155
更新日期：1985-12-01 00:00:00
abstract：:The clinical course of 6 children with primary intestinal lymphangiectuasia who have been treated with low fat medium chain triglyceride-supplemented diets for between 3 and 8 years (4 for longer than 5 years) is described. Though laboratory findings indicate continuing chyle leak, evidence for long-term benefit from ...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.50.4.269
更新日期：1975-04-01 00:00:00
abstract：BACKGROUND:Children with type 1 diabetes should be encouraged to participate in physical activity because exercise can benefit insulin sensitivity and improve known risk factors for atherosclerosis. METHODS:Physical activity patterns of 127 children and adolescents with stable type 1 diabetes were investigated by 24 h...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.2005.075283
更新日期：2005-12-01 00:00:00
abstract：:We describe two cases of a non-epileptic florid movement disorder presenting as status epilepticus. Both patients presented with florid jerking of the limbs and eyes. Convulsive status epilepticus related to presumed meningitis or encephalitis was suspected in both cases. The patients received treatment for seizures, ...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.2009.160044
更新日期：2009-11-01 00:00:00
abstract：OBJECTIVES:To describe common patterns of bath water scald injuries in children, to examine differences between accidental and non-accidental bath water scalds in children, and to examine potential for prevention. DESIGN:A two year six month retrospective analysis of admissions to a specialist burns unit. SETTING:The...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.71.2.156
更新日期：1994-08-01 00:00:00
abstract：AIMS:To determine whether current and postpartum maternal depression and low maternal intelligence are risk factors for malnutrition in children. METHODS:In rural South India 72 children with malnutrition were identified from a central register; 72 controls were matched for age, gender, and residence. RESULTS:Major d...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.2002.009738
更新日期：2004-04-01 00:00:00
abstract：OBJECTIVE:To develop a clinical algorithm to identify paediatric patients who should be offered HIV testing in a setting of moderate HIV prevalence and limited resources. METHODS:In a prospective cross-sectional study at Port Moresby General Hospital, Papua New Guinea, carers of inpatients were offered HIV testing and...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.2009.179143
更新日期：2011-01-01 00:00:00
abstract：:We describe a 21 month old male infant who presented with failure to thrive associated with severe hypokalaemia and metabolic acidosis, together with hypomagnesaemia. Evaluation revealed marked renal and probable faecal potassium wasting, distal renal tubular acidosis, mild urinary magnesium wasting, and a normal gast...
journal_title：Archives of disease in childhood
pub_type： 杂志文章
doi：10.1136/adc.84.6.504
更新日期：2001-06-01 00:00:00
