Abstract:
BACKGROUND:Antiepileptics including benzodiazepines have long been recognized to provoke seizures and precipitate status epilepticus occasionally. This has a special clinical importance in the case of diazepam because of its use as first choice medication in its management. This report is intended to highlight the clinical importance of such a situation. METHODS:The clinical course of a 28-year old man with complex partial status, which lasted for two months, is described in detail. RESULTS:Paradoxic response to diazepam was documented under EEG monitoring. A similar response was also noted for midazolam, and had probably contributed in exacerbating and prolonging the duration of status. CONCLUSION:Paradoxic response to diazepam and midazolam is rare, but may be under-recognized. It should be considered in the setting of refractory status epilepticus.
journal_name
Arch Med Resjournal_title
Archives of medical researchauthors
Al Tahan Adoi
10.1016/s0188-4409(00)00043-6subject
Has Abstractpub_date
2000-01-01 00:00:00pages
101-4issue
1eissn
0188-4409issn
1873-5487pii
S0188-4409(00)00043-6journal_volume
31pub_type
杂志文章abstract:BACKGROUND:Wind instrument playing requires a strenuous respiratory activity. Previous studies investigating effect of wind instrument playing on pulmonary function are equivocal. METHODS:In the present study, 34 male, non-smoker wind players in a military band were compared with 44 healthy non-smoker males by pulmona...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2005.09.015
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Molluscum contagiosum has a worldwide occurrence and its primary mode of transmission is via direct human contact including sexual means. The aim of the study was to implement a polymerase chain reaction-based assay for detection and subtyping of Molluscum contagiosum virus (MCV) in skin lesions diagnosed wi...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2005.05.020
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:We undertook this study to compare the effectiveness and safety of antenatal daily and weekly supplementation with iron, folic acid, and vitamin B(12) in healthy, pregnant women who were not anemic at gestational week 20. METHODS:Women with singleton pregnancies and blood hemoglobin (Hb) >115 g/L at gestati...
journal_title:Archives of medical research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.arcmed.2005.11.011
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Considering results among previous studies regarding the relationship of red blood cell distribution width (RDW) and all-cause mortality in chronic kidney disease (CKD) patients, we aimed to perform a comprehensive meta-analysis to evaluate the potential association between RDW and all-cause mortality in CKD...
journal_title:Archives of medical research
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.arcmed.2017.06.009
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:Lipoprotein(a) [Lp(a)] is an independent cardiovascular risk factor. We present real-life characteristics of patients with increased Lp(a) levels attending a University Lipid Clinic. METHODS:We retrospectively studied patients attending the University of Ioannina Hospital Lipid Clinic with Lp(a) levels ≥30 m...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2020.12.003
更新日期:2020-12-27 00:00:00
abstract:BACKGROUND:It has been recently shown that oral administration of D002, a mixture of higher aliphatic primary alcohols isolated from beeswax, inhibits rat microsomal lipid peroxidation. This justified the present attempt to investigate whether D002 also exerts antioxidant effects in humans. METHODS:The effects of D002...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0188-4409(01)00315-0
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:Studies in platelet of 5-HT uptake transporters have been performed using binding assay methodology designed for ligand-receptor interactions; however, uptake transporters present requirements that may question the validity of these particular binding assays. METHODS:To explore methodologic aspects that may...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2003.03.001
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:The benefits of a special stroke care unit (SSCU) over a non-specialized stroke care unit (NSSCU) is well documented in the literature. However, there are concerns that the benefits seen in the SSCU do not consider clinical risk factors that affect thrombolysis therapy. METHOD:Retrospective data were collec...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2019.01.002
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND AND AIMS:Streptococcus pneumoniae is the leading cause of acute otitis media, pneumonia, meningitis, and sepsis. The heptavalent pneumococcal conjugate vaccine (PCV7) was incorporated into the national immunization program in Mexico in 2008. The aim of the study was to analyze the frequency of S. pneumoniae ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2015.02.004
更新日期:2015-02-01 00:00:00
abstract::Glutamate neurotransmitter action on postsynaptic receptors is terminated by its clearance from the synaptic cleft by transporter proteins located in neurons and glial cells. Failure of glutamate removal can lead to neuronal death due to its well-known neurotoxic properties. Glutamate transporters are dependent on ext...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:10.1016/j.arcmed.2005.05.014
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:The present study was designed to examine whether resveratrol, a potent antioxidant, protects against renal ischemia-reperfusion (I/R) injury. METHODS:Wistar albino rats were unilaterally nephrectomized and subjected to 45 min of renal pedicle occlusion followed by 6 h of reperfusion. Resveratrol (RVT, 30 m...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2006.04.003
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND AND AIMS:Identifying gene-environment interaction in the context of multiple environmental factors has been a challenging task. We aimed to use conditional inference tree (CTREE) to strata myocardial infarction (MI) risk synthesizing information from both genetic and environmental factors. METHODS:We conduc...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2017.12.001
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:There is a need to assess whether human immunodeficiency virus (HIV)-infected patients are more likely than noninfected individuals to have any of the specific lipoprotein combination profiles identified as the best predictors of future cardiovascular disease in the general population. METHODS:One hundred f...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2007.06.012
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Neurofibromatosis type I (NF1) is one of the most common neurocutaneous syndromes characterized by development of adult neurofibromas which is mainly made up of Schwann cells. The disease is generally accepted to be caused by inactivation mutation of Nf1 gene. And Nf1 deficiency had been reported to...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2017.11.014
更新日期:2017-08-01 00:00:00
abstract::Three exoglucanase genes have been described in Saccharomyces cerevisiae. The bulk of the exoglucanase (EXO) activity is encoded by the EXG1 gene, whose primary gene product is differentially glycosylated during its transit to the cell surface to yield three isoenzymes: EXOI, EXOII and EXOII1/2. EXOII, the major isoen...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1993-10-01 00:00:00
abstract::To determine the effect of low protein and corn-based diets on the maturation of cerebellum, three groups of young rats were fed during a period of 6 weeks with different diets; 23 and 8% of protein (Purina-Chow base) and a corn-based diet (8% protein). At the end of that period, the concentration of free amino acids ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::The number of patients requiring lung transplantation is increasing, with a significant unmet demand for grafts. Ex vivo lung perfusion has been developed to increase graft recruitment. The major complications of lung transplantation include chronic allograft dysfunction (CLAD) whose cumulative incidence ranges from 4...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2015.03.004
更新日期:2015-04-01 00:00:00
abstract::In Mexico, hypercholesterolemia has become a major public health problem particularly in the states of the north of the country and in Mexico City, where a prevalence of 20% has been reported. Schemes of treatment have now been reinforced by the appearance of new cholesterol reducing drugs. The objective of the study ...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract:BACKGROUND:This investigation was undertaken to study the clinical characteristics and the humoral immune pattern in lymphedema patients undergoing O-beta-hydroxy-ethyl rutoside therapy. METHODS:A complete physical examination was performed on 27 lymphedema patients (postmastectomy and postphlebitis) and 17 healthy co...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-4409(00)00272-1
更新日期:2001-03-01 00:00:00
abstract::Phagocytic host defense mechanisms play a pivotal role in the prevention and containment of invasive, disseminated candidiasis, aspergillosis, and other opportunistic mycoses. The specific processes involved depend upon both the species, growth phase, and surface properties of the fungal target and the type and differ...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Adrenoceptors have been involved in the regulation of hepatocyte proliferation after partial hepatectomy, as well as in primary culture. This report characterizes alpha 1- and beta-adrenoceptor change during the time-course of liver regeneration in adult Wistar Kyoto rats. METHODS:Saturation binding assays ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-0128(98)00028-1
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND AND AIMS:Genome-wide association studies recently found IGF2BP2 rs4402960 polymorphism associated with enhanced risk of type 2 diabetes mellitus (T2DM). Numerous studies have been published to replicate the association. However, results were inconsistent and inconclusive. To clarify the relationship of IGF2B...
journal_title:Archives of medical research
pub_type: 杂志文章,meta分析
doi:10.1016/j.arcmed.2011.08.001
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND AND AIMS:The present study analyzed the relationship between TP53 codon 72 polymorphisms and the clinical outcome of advanced gastric cancer patients receiving capecitabine plus paclitaxel chemotherapy. METHODS:Three hundred patients with advanced gastric cancer treated with paclitaxel and capecitabine comb...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章
doi:10.1016/j.arcmed.2015.12.001
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND AND AIMS:The major limiting factor in therapeutic application of mesenchymal stem cells (MSCs) is their high vulnerability during the early days of transplantation. Hence, researchers have been encouraged to find various strategies to make the cells resistant to different stresses before and after transplant...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2013.03.006
更新日期:2013-04-01 00:00:00
abstract::A matrix metalloproteinase with selective affinity for collagen was identified and partially purified from normal rat kidney. A two-step purification procedure consisting of gel filtration and affinity chromatography on Sepharose 4B-collagen resulted in an increase in specific activity of more than 3,000 times. The pa...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract::Public and governmental concern regarding increasing cancer mortality trends in children in Mexico led us to investigate the current situation of childhood cancer in this country, as well as to discuss the reasons for which no decline in total and childhood cancer mortality has been documented during the past decades....
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-4409(00)00094-1
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Tumor necrosis factor-alpha (TNF-alpha) is found to play important roles in acute myocardial infarction (AMI). Ventricular arrhythmias arising from AMI are leading causes of sudden cardiac death (SCD). We sought to clarify the effect of TNF-alpha early expression on ventricular arrhythmias in rats with AMI a...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2007.10.004
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Selenoproteins S (SELS or VIMP) may regulate cytokine production, and thus play a key role in the control of the inflammatory response. METHODS:This study consisted of 136 Iranian patients with cardiovascular disease (65 MetS-affected and 71 MetS un-affected individuals) in the selengene study. Expression o...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2020.05.005
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND AND AIMS:The cardiac regulator of G-protein signaling 2 (RGS2) negatively regulates G-protein-coupled receptor signaling. The C1114G polymorphism reduces RGS2 gene expression. This molecular disorder may be one of the important factors influencing progress of neurally mediated syncope. The aim of the study w...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2009.02.005
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND AND AIMS:T-helper (Th) cells involved in the pathogenesis of multiple sclerosis (MS) represent a functionally heterogeneous population defined by their cytokine secretion profile. The effects of immunotherapeutic drugs on the cytokine network are still not fully clarified. This study aimed to investigate ser...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2014.08.001
更新日期:2014-08-01 00:00:00