Abstract:
UNLABELLED:VAP is a complex nosocomial infection, the disease expression and resulting patient outcome of which is dependent on host factors, the causative organism, the timing and adequacy of treatment, and the presence of intrinsic or inducible antibiotic resistance. Significant improvements have been achieved in our ability to reduce the occurrence of VAP in the hospital setting. Clinicians caring for mechanically ventilated patients should strive to develop focused programs for the prevention of VAP, other nosocomial infections, and the occurrence of antibiotic-resistant infections at their institutions. The benefits of such programs are well demonstrated. The components of a PDSA (Plan-Do-STUDY-Act) model that can be simply employed to develop a VAP prevention program are as follows: Stages Plan: 1. Identify potentially modifiable risk factors for VAP at the institutional level. 2. Develop a strategy to modify or prevent the occurrence of these risk factors. [figure: see text] Do: 1. Carry out the planned intervention strategy. 2. Identify problems in the implementation of the designed intervention. 3. Update the intervention with solutions for the identified problems. 4. Collect basic data (e.g., VAP rates, severity of illness). STUDY:1. Analyze data. 2. Summarize the results. Act: 1. Determine the overall success or failure of the intervention. 2. Identify potential modifications to improve the intervention strategy. 3. Prepare for next PDSA cycle. Inherent in the development and application of such programs is the concept that they are continuous processes striving to improve clinical performance over time (Fig. 3). At any given institution, the most likely approach to the prevention of NP and VAP will be a multifaceted one, employing interventions aimed at reducing the occurrence of aerodigestive tract colonization with pathogenic bacteria and aspiration. To be successful, such quality improvement programs must be embraced at the institutional level. Only in this way can hospitals hope to successfully reduce their rates of VAP and sustain or improve upon those efforts over time.
journal_name
Clin Chest Medjournal_title
Clinics in chest medicineauthors
Kollef MHdoi
10.1016/s0272-5231(05)70242-2subject
Has Abstractpub_date
1999-09-01 00:00:00pages
653-70issue
3eissn
0272-5231issn
1557-8216pii
S0272-5231(05)70242-2journal_volume
20pub_type
杂志文章,评审abstract::Our understanding of chronic bronchitis has been hampered by the fact that the diagnosis is based upon historical evidence of recurrent cough and sputum without any requirement that certain physiologic or microscopic criteria be met. Despite the fact that epidemiological studies have implicated viruses, bacteria, and ...
journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:
更新日期:1981-01-01 00:00:00
abstract::Recent progress in medical therapies has diminished the role of transplantation in the management of PPH during the past decade. Drug therapy is not effective in some patients, responses to therapy are not sustained over time in others, and drug side effects eventually limit the benefits of treatment in a few more. Lu...
journal_title:Clinics in chest medicine
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abstract::Biologic drugs have revolutionized the treatment of certain hematologic, autoimmune, and malignant diseases, but they may place patients at risk for reactivation or acquisition of tuberculosis. This risk is highest with the tumor necrosis factor-alpha (TNF-α) inhibitors. Amongst this class of drugs, the monoclonal ant...
journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ccm.2019.07.003
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:
更新日期:1988-03-01 00:00:00
abstract::Lung transplantation is an accepted treatment for a large number of end-stage pulmonary diseases. There are several complications that pertain specifically to lung transplant recipients, including airway ischemia, reperfusion edema, infections, acute rejection, obliterative bronchiolitis, and other postoperative probl...
journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/s0272-5231(05)70257-4
更新日期:1999-12-01 00:00:00
abstract::Several medications have been associated with the development of the BOOP lesion. Often, symptoms include nonproductive cough and shortness of breath with bilateral crackles by examination. Occasionally, there is fever and rash, and, rarely, eosinophilia. The chest radiograph usually shows bilateral patchy infiltrates...
journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/S0272-5231(03)00140-0
更新日期:2004-03-01 00:00:00
abstract::Many different therapeutic compounds are associated with pulmonary toxicity. Although the mechanism of injury for many of these compounds is poorly defined, several compounds are believed to produce alterations in normal lung biochemistry. These mechanisms of injury in both clinical and experimental models are discuss...
journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:
更新日期:1989-03-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/s0272-5231(05)70420-2
更新日期:1997-12-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ccm.2015.02.005
更新日期:2015-06-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/s0272-5231(05)70387-7
更新日期:1997-06-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ccm.2006.11.009
更新日期:2007-03-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ccm.2005.08.004
更新日期:2006-03-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:
更新日期:1984-12-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:
更新日期:1986-03-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章
doi:
更新日期:1985-12-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/s0272-5231(03)00067-4
更新日期:2002-03-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:
更新日期:1984-06-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:
更新日期:1990-03-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:
更新日期:1989-06-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ccm.2009.02.010
更新日期:2009-06-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ccm.2010.10.007
更新日期:2011-03-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ccm.2009.02.003
更新日期:2009-06-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:
更新日期:1993-09-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ccm.2018.01.011
更新日期:2018-06-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ccm.2020.02.004
更新日期:2020-06-01 00:00:00
abstract::Because of physiologic changes associated with aging and the development of chronic illness, the elderly will continue to be at risk for catastrophic illnesses including adult respiratory distress syndrome (ARDS). Current management of elderly patients with ARDS is only supportive and focused on avoiding complications...
journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:
更新日期:1993-09-01 00:00:00
abstract::Current advances in guided bronchoscopy methods permit minimally invasive access to essentially any area of the lungs. This provides a potential means to treat patients with localized lung malignancies who might not otherwise tolerate conventional treatment, which commonly relies on surgical resection. Ablation method...
journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ccm.2017.11.014
更新日期:2018-03-01 00:00:00
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journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:
更新日期:1989-03-01 00:00:00
abstract::This article focuses primarily on the recent literature on abdominal compartment syndrome (ACS) and the definitions and recommendations published by the World Society for the Abdominal Compartment Syndrome. The definitions regarding increased intra-abdominal pressure (IAP) are listed and are followed by an overview of...
journal_title:Clinics in chest medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ccm.2008.09.003
更新日期:2009-03-01 00:00:00