Effect of in situ plaque mineral supplementation on the state of saturation of plaque fluid during sugar-induced acidogenesis.

Abstract:

:Dental plaque fluid is normally supersaturated with respect to enamel mineral but this may change to a state of undersaturation when plaque pH falls following sugar exposure, placing the adjacent enamel at risk of caries. We have determined the saturation status of the fluid in both resting and fermenting plaque following mineral supplementation. Eleven subjects abstained from oral hygiene and rinsed their mouth 3 times/d for 3 d with a placebo solution or with test solutions designed to enrich plaque with hydroxyapatite or fluorhydroxyapatite. On the morning of day 4, plaque samples were collected before and after exposure to 10% sucrose. Compared to the placebo, use of the test rinses resulted in significantly higher concentrations of Ca, P and F in plaque residue. In plaque fluid, higher post-sucrose Ca2+ free concentrations and saturation levels with respect to enamel mineral and fluorapatite were found after use of the hydroxyapatite rinse compared to the placebo, effects that probably resulted from the release of cell-bound Ca2+ as well as from the dissolution of apatite. Thus, some evidence was obtained that the test mouthrinses can counteract the fall in saturation level found when plaque is exposed briefly to sucrose. Potential long-term benefits of the test mouthrinses deserve further study.

journal_name

Eur J Oral Sci

authors

Pearce EI,Margolis HC,Kent RL Jr

doi

10.1046/j.0909-8836.1999.eos107404.x

subject

Has Abstract

pub_date

1999-08-01 00:00:00

pages

251-9

issue

4

eissn

0909-8836

issn

1600-0722

journal_volume

107

pub_type

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