Abstract:
:The purpose was to investigate if antigenic fragments of aggrecan and cartilage oligomeric matrix protein (COMP) are detectable by enzyme-linked immunosorbent assay in lavage fluids from the temporomandibular joint (TMJ) and to examine if the relative content of these cartilage markers changes during development of osteoarthrosis (OA) after diskectomy. Lavage fluid was obtained at surgery and 6 months postoperatively in 13 patients. Computed tomography or magnetic resonance imaging was without evidence of hard-tissue changes prior to surgery in all patients. In 9 of the patients, sufficient material for analysis was obtained at both examinations. Aggrecan and COMP were detectable in all but 2 fluids, in which the COMP levels were below detection limit. The aggrecan/COMP ratio increased in all 9 patients during the 6-month period, indicating increased release of aggrecan relative to COMP fragments. The changed aggrecan/COMP ratio possibly reflects increased cartilage turnover during development of OA. Changes compatible with OA were present on computed tomography in all cases at the 6-month follow-up. This study shows that the lavage procedure is feasible for obtaining synovial fluid from the TMJ for immunochemical analyses of tissue-derived macromolecules.
journal_name
Eur J Oral Scijournal_title
European journal of oral sciencesauthors
Flygare L,Wendel M,Saxne T,Ericson S,Eriksson L,Petersson A,Rohlin Mdoi
10.1111/j.1600-0722.1997.tb00254.xsubject
Has Abstractpub_date
1997-08-01 00:00:00pages
369-72issue
4eissn
0909-8836issn
1600-0722journal_volume
105pub_type
杂志文章abstract::It has been suggested that occlusal interferences may lead to pain and tenderness of the masticatory muscles. Tender jaw muscles are more sensitive to pressure pain, as assessed by means of pressure algometry. We tested the effects of occlusal interferences on the pressure pain threshold of the jaw muscles by means of...
journal_title:European journal of oral sciences
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0722.2006.00298.x
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abstract::The aim of this investigation was to study the intraoral pH response on tooth surfaces in relation to dental erosion during and after drinking a sugar-free cola-type soft drink. Six different methods of drinking were tested in a randomized order: holding; short-sipping; long-sipping; gulping; nipping; and sucking. Two...
journal_title:European journal of oral sciences
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2004-12-01 00:00:00
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abstract::The present study evaluated the failure risks of an endodontically treated premolar with severely damaged coronal hard tissue and restored with either a computer-aided design/computer-aided manufacturing (CAD/CAM) ceramic endocrown or a classical crown configuration. Two, three-dimensional finite element maxillary pre...
journal_title:European journal of oral sciences
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journal_title:European journal of oral sciences
pub_type: 杂志文章,随机对照试验
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journal_title:European journal of oral sciences
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pub_type: 历史文章,杂志文章
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journal_title:European journal of oral sciences
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journal_title:European journal of oral sciences
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journal_title:European journal of oral sciences
pub_type: 杂志文章
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journal_title:European journal of oral sciences
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journal_title:European journal of oral sciences
pub_type: 杂志文章
doi:10.1046/j.0909-8836.2001.101160.x
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abstract::The effect of the dentifrice ingredient triclosan (2,4,4'-trichloro-2'-hydroxyldiphenyl ether) on the production of interleukin (IL)-1beta and IL-6 was studied in human gingival fibroblasts challenged with tumor necrosis factor alpha (TNFalpha) in vitro. When gingival fibroblasts were treated simultaneously with tricl...
journal_title:European journal of oral sciences
pub_type: 杂志文章
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更新日期:1998-04-01 00:00:00
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journal_title:European journal of oral sciences
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journal_title:European journal of oral sciences
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abstract::Temporomandibular joint (TMJ) histology was investigated in 8 female Scandinavian moose. 5 were 1-year-old with a carcass weight (cw) of 125-140 kg, and 3 were 2-years-old (160-175 kg cw). The condylar articular surface consisted of a connective tissue lining with parallel collagen fibres. Numerous blood vessels were ...
journal_title:European journal of oral sciences
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journal_title:European journal of oral sciences
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journal_title:European journal of oral sciences
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abstract::Comminution of food is the composite result of selection and breakage. Selection is characterised by the chance that a food particle will at least be damaged by the teeth during chewing. For any size, this chance equals the ratio between the weight of damaged or broken particles and that of all initial particles. The ...
journal_title:European journal of oral sciences
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abstract::The Enamel Defects Index (EDI) was created based on three innovative principles: (i) a basic level of the three major categories of defects; (ii) more detailed subcategories of each major category; and (iii) each category scored independently as present [1] or absent [0], simplifying decision making. The aim of this i...
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journal_title:European journal of oral sciences
pub_type: 杂志文章
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journal_title:European journal of oral sciences
pub_type: 杂志文章
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