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Oversized grafts in children.

Abstract：

OBJECTIVE:To evaluate the efficacy of oversized corneal grafts in the pediatric age group. DESIGN:Prospective, nonrandomized clinical trial. PARTICIPANTS AND INTERVENTION:Forty pediatric patients with unilateral or bilateral corneal opacification of congenital or acquired origin underwent corneal grafting surgery over a period of 2 years using donor corneal buttons oversized by 1 mm. MAIN OUTCOME MEASURES:The parameters evaluated were indications for keratoplasty, graft clarity, visual acuity, keratometry, spherical equivalent, anterior chamber depth, and complications. RESULTS:Corneal ulceration was the most common cause of corneal opacification (25%), followed by trauma (20%) and sclerocornea (20%). At 1 year, clear grafts were achieved in 85% of the cohort. The average keratometry at the end of 1 year was 43.28 +/- 1.65 diopters (D) in the congenital opacity group and 43.04 +/- 2.20 D in the acquired group. The keratometric astigmatism was 3.60 +/- 2.60 D in the congenital group and 2.52 +/- 2.20 D in the acquired group. Oversized grafts provided an adequate anterior chamber depth of 2.20 +/- 0.612 mm in the congenital group and 2.36 +/- 0.302 mm in the acquired group. Visual acuity of 20/80 or better was recorded in only 30% of cases in the congenital group as opposed to 47% with acquired opacities. Nine cases had episodes of graft rejection. CONCLUSION:Oversizing donor buttons by 1 mm provides adequate anterior chamber depth and increases the morphologic success of corneal grafting in children.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Vajpayee RB,Ramu M,Panda A,Sharma N,Tabin GC,Anand JR

doi

10.1016/S0161-6420(99)90174-4

subject

Has Abstract

pub_date

1999-04-01 00:00:00

pages

829-32

issue

4

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(99)90174-4

journal_volume

106

pub_type

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