Downgaze eyelid position in patients with blepharoptosis.

Abstract:

PURPOSE:To prospectively examine the change in upper eyelid position on downgaze in patients with blepharoptosis. METHODS:Upper eyelid margin to corneal light reflex distance (uMRD) was measured in primary gaze and in 30 degrees to 40 degrees downgaze in 50 consecutive patients with acquired ptosis and 10 consecutive patients with congenital ptosis. RESULTS:For the acquired ptosis group, the mean change in uMRD on downgaze was -0.8 mm (range, -2.5 to 1.0 mm), with one patient (2%) showing an increase, 10 (20%) no change, and 39 (78%) a decrease in upper eyelid position. For the congenital group, the mean change in uMRD on downgaze was +2.1 mm (range, 1.0-4.0 mm), with all patients demonstrating an increase in upper eyelid position. The difference between the group means was highly significant (P < 0.001). CONCLUSIONS:Worsening of ptosis on downgaze is common with acquired ptosis and likely represents a normal physiologic process, which may exacerbate functional impairment of activities (i.e., reading) in this gaze position. The consistent increase in upper eyelid position on downgaze in patients with typical congenital ptosis is an abnormal differentiating sign.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Meyer DR,Rheeman CH

doi

10.1016/s0161-6420(95)30837-8

subject

Has Abstract

pub_date

1995-10-01 00:00:00

pages

1517-23

issue

10

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(95)30837-8

journal_volume

102

pub_type

杂志文章
  • Efficacy and Safety of Intravitreal Sirolimus for Noninfectious Uveitis of the Posterior Segment: Results from the Sirolimus Study Assessing Double-Masked Uveitis Treatment (SAKURA) Program.

    abstract:PURPOSE:To evaluate the efficacy and safety of intravitreal sirolimus in the management of noninfectious uveitis of the posterior segment (NIU-PS). DESIGN:Combined analysis of 2 phase 3, randomized, double-masked, multinational, 6-month studies. PARTICIPANTS:Adults with active NIU-PS (intermediate uveitis, posterior ...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ophtha.2020.03.033

    authors: Merrill PT,Clark WL,Banker AS,Fardeau C,Franco P,LeHoang P,Ohno S,Rathinam SR,Ali Y,Mudumba S,Shams N,Nguyen QD,Sirolimus Study Assessing Double-Masked Uveitis Treatment (SAKURA) Study Group.

    更新日期:2020-10-01 00:00:00

  • The Relationship between Medicare Payment and Service Volume for Retina Procedures from 2005 through 2009.

    abstract:PURPOSE:To calculate the relationship between Medicare payment and service volume for the 3 highest-volume retina procedures: intravitreal injection (Current Procedural Terminology [CPT] code 67028), laser treatment for retinal edema (CPT code 67210), and laser treatment for proliferative retinopathy (CPT code 67228). ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2015.04.040

    authors: Gong D,Jun L,Tsai JC

    更新日期:2015-08-01 00:00:00

  • Posterior Vitreous Detachment as Observed by Wide-Angle OCT Imaging.

    abstract:PURPOSE:Posterior vitreous detachment (PVD) plays an important role in vitreoretinal interface disorders. Historically, observations of PVD using OCT have been limited to the macular region. The purpose of this study is to image the wide-angle vitreoretinal interface after PVD in normal subjects using montaged OCT imag...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2018.02.039

    authors: Tsukahara M,Mori K,Gehlbach PL,Mori K

    更新日期:2018-09-01 00:00:00

  • Retinal crystals in type 2 idiopathic macular telangiectasia.

    abstract:PURPOSE:To characterize the phenotype and investigate the associations of intraretinal crystalline deposits in a large cohort with type 2 idiopathic macular telangiectasia (MacTel). DESIGN:Case-control study. PARTICIPANTS:Patients with and without retinal crystals from the Macular Telangiectasia Project, an internati...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ophtha.2011.05.022

    authors: Sallo FB,Leung I,Chung M,Wolf-Schnurrbusch UE,Dubra A,Williams DR,Clemons T,Pauleikhoff D,Bird AC,Peto T,MacTel Study Group.

    更新日期:2011-12-01 00:00:00

  • MK-507 versus sezolamide. Comparative efficacy of two topically active carbonic anhydrase inhibitors.

    abstract::Topical carbonic anhydrase inhibitors MK-507 and sezolamide hydrochloride (previously known as MK-417) were compared in a double-masked, randomized, placebo-controlled study in 82 patients with bilateral primary open-angle glaucoma or ocular hypertension. MK-507 was given every 8 or 12 hours, sezolamide every 8 hours,...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0161-6420(91)32295-4

    authors: Lippa EA,Schuman JS,Higginbotham EJ,Kass MA,Weinreb RN,Skuta GL,Epstein DL,Shaw B,Holder DJ,Deasy DA

    更新日期:1991-03-01 00:00:00

  • Prognostic accuracy of the mean of the largest nucleoli, vascular patterns, and PC-10 in posterior uveal melanoma.

    abstract:OBJECTIVE:This study aimed to compare the prognostic value and the predictive accuracy of the PC-10 cell cycling marker with the largest tumor diameter, the mean of the largest nucleoli, and vascular patterns in posterior uveal melanoma. DESIGN:The study design was a case-control study. PARTICIPANTS:Eyes enucleated f...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/S0161-6420(98)93032-9

    authors: Seregard S,Spångberg B,Juul C,Oskarsson M

    更新日期:1998-03-01 00:00:00

  • Analysis of the Stargardt disease gene (ABCR) in age-related macular degeneration.

    abstract:PURPOSE:Age-related macular degeneration (AMD) is a complex genetic disorder and the leading cause of severe vision loss in the elderly. The Stargardt disease gene (ABCR) has been proposed as a major genetic risk factor in AMD. The purpose of this study was to evaluate the authors' AMD population for the specific ABCR ...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/S0161-6420(99)90449-9

    authors: De La Paz MA,Guy VK,Abou-Donia S,Heinis R,Bracken B,Vance JM,Gilbert JR,Gass JD,Haines JL,Pericak-Vance MA

    更新日期:1999-08-01 00:00:00

  • Glaucoma after pars plana vitrectomy and silicone oil injection for complicated retinal detachments.

    abstract:OBJECTIVE:To determine the incidence and associations of glaucoma after pars plana vitrectomy (PPV) and silicone oil injection (SOI) for complicated retinal detachments and the response to treatment. DESIGN:Retrospective noncomparative case series. PARTICIPANTS:A total of 150 eyes of 150 patients who had completed a ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/S0161-6420(99)90017-9

    authors: Honavar SG,Goyal M,Majji AB,Sen PK,Naduvilath T,Dandona L

    更新日期:1999-01-01 00:00:00

  • Comparison of intraocular lens power calculation formulae in pediatric eyes.

    abstract:PURPOSE:To evaluate accuracy of intraocular lens (IOL) power calculation formulae (SRK II, SRK/T, Holladay 1, Hoffer Q) in pediatric eyes. DESIGN:Retrospective case series. PARTICIPANTS:One hundred thirty-five eyes of 96 children with congenital, developmental, or acquired cataracts who underwent uncomplicated catara...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2009.12.031

    authors: Nihalani BR,VanderVeen DK

    更新日期:2010-08-01 00:00:00

  • Primary cystadenocarcinoma of the lacrimal gland.

    abstract:PURPOSE:To report a patient with a cystadenocarcinoma of the lacrimal gland, a tumor not previously described in the ophthalmic literature. Salivary gland cystadenocarcinomas constitute a distinct group of epithelial malignancies characterized by an invasive, predominantly cystic pattern of growth that have an indolent...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/S0161-6420(03)00490-1

    authors: Devoto MH,Croxatto JO

    更新日期:2003-10-01 00:00:00

  • Visual recovery in macula-off rhegmatogenous retinal detachments.

    abstract:OBJECTIVE:This study aimed to review the best postoperative visual recovery in patients with macula-off detachments of 7 days' duration or less. DESIGN:Noncontrolled, prospective, interventional case series. PARTICIPANTS:A total of 104 patients with macula-off detachments of 7 days or less were studied, and the time ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/S0161-6420(98)91142-3

    authors: Ross WH,Kozy DW

    更新日期:1998-11-01 00:00:00

  • Management of exposed hydroxyapatite orbital implants.

    abstract:BACKGROUND:Porous coralline hydroxyapatite orbital implants have gained significant popularity for use in anophthalmic sockets. Several reports have noted increased rates of early implant exposure. METHODS:Six patients with exposure complications of primary hydroxyapatite implants after enucleation or evisceration wer...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(94)31112-2

    authors: Kim YD,Goldberg RA,Shorr N,Steinsapir KD

    更新日期:1994-10-01 00:00:00

  • Comparison of external dacryocystorhinostomy with nonlaser endonasal dacryocystorhinostomy.

    abstract:OBJECTIVE:We compared outcomes after dacryocystorhinostomies (DCRs) performed by the traditional external approach (EX-DCR) or by a nonlaser, nonendoscopic endonasal approach (EN-DCR). DESIGN:Retrospective, nonrandomized, comparative interventional case series. PARTICIPANTS:A total of 354 consecutive cases of DCR wer...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(02)01452-5

    authors: Dolman PJ

    更新日期:2003-01-01 00:00:00

  • The Evolution of Outer Retinal Tubulation, a Neurodegeneration and Gliosis Prominent in Macular Diseases.

    abstract:PURPOSE:To document outer retinal tubulation (ORT) formation in advanced retinal disorders. DESIGN:Retrospective, observational study. PARTICIPANTS:Consecutive cases with retinal diseases showing outer retinal disruption and atrophy of the retinal pigment epithelium (RPE) associated with ORT on spectral-domain (SD) o...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2017.03.043

    authors: Dolz-Marco R,Litts KM,Tan ACS,Freund KB,Curcio CA

    更新日期:2017-09-01 00:00:00

  • Retreatment after photorefractive keratectomy for low myopia.

    abstract:OBJECTIVE:The purpose of the study was to evaluate the results of retreatment for low myopia after primary photorefractive keratectomy (PRK). DESIGN:A prospective study. PARTICIPANTS:A total of 48 eyes of 37 patients from 566 eyes of 331 patients originally treated for myopia of up to -6 diopters (D) were studied. I...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/S0161-6420(98)97018-X

    authors: Rozsíval P,Feuermannová A

    更新日期:1998-07-01 00:00:00

  • Adjunctive glaucoma therapy. A comparison of apraclonidine to dipivefrin when added to timolol maleate.

    abstract::The authors compared the additive intraocular pressure (IOP)-lowering effects of two different topical medications, apraclonidine hydrochloride and dipivefrin hydrochloride, when used in conjunction with timolol maleate. Eighteen patients with elevated IOPs entered a randomized, double-masked, cross-over study. Each u...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0161-6420(89)32977-0

    authors: Morrison JC,Robin AL

    更新日期:1989-01-01 00:00:00

  • Toward zero effective phacoemulsification time using femtosecond laser pretreatment.

    abstract:OBJECTIVE:To compare effective phacoemulsification time after femtosecond laser pretreatment with conventional phacoemulsification and the associated effect on visual outcomes and endothelial cell loss. DESIGN:Prospective, consecutive, single-surgeon case-control study. CONTROLS:Controls underwent phacoemulsification...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2012.11.045

    authors: Abell RG,Kerr NM,Vote BJ

    更新日期:2013-05-01 00:00:00

  • IntraLase-enabled astigmatic keratotomy for post-keratoplasty astigmatism: on-axis vector analysis.

    abstract:PURPOSE:To determine the refractive predictability, stability, efficacy, and complication rate of femtosecond laser-enabled astigmatic keratotomy for post-keratoplasty astigmatism. DESIGN:A retrospective case series (pilot study). PARTICIPANTS:Thirty-seven eyes of 34 patients. METHODS:All eyes underwent IntraLase-en...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2009.10.041

    authors: Kumar NL,Kaiserman I,Shehadeh-Mashor R,Sansanayudh W,Ritenour R,Rootman DS

    更新日期:2010-06-01 00:00:00

  • Two-Year Clinical Trial of the Low-Concentration Atropine for Myopia Progression (LAMP) Study: Phase 2 Report.

    abstract:PURPOSE:To evaluate the efficacy and safety of 0.05%, 0.025%, and 0.01% atropine eye drops over 2 years to determine which is the optimal concentration for longer-term myopia control. DESIGN:Randomized, double-masked trial extended from the Low-Concentration Atropine for Myopia Progression (LAMP) Study. PARTICIPANTS:...

    journal_title:Ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ophtha.2019.12.011

    authors: Yam JC,Li FF,Zhang X,Tang SM,Yip BHK,Kam KW,Ko ST,Young AL,Tham CC,Chen LJ,Pang CP

    更新日期:2020-07-01 00:00:00

  • Results of phase III excimer laser photorefractive keratectomy for myopia. The Summit PRK Study Group.

    abstract:OBJECTIVE:The purpose of the study is to determine safety and efficacy outcomes of excimer laser photorefractive keratectomy (PRK) for the treatment of mild-to-moderate myopia. DESIGN:A prospective, multicenter, phase III clinical trial. PARTICIPANTS:A total of 701 eyes of 701 patients were entered in the study; 612 ...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1016/s0161-6420(97)30073-6

    authors: Hersh PS,Stulting RD,Steinert RF,Waring GO 3rd,Thompson KP,O'Connell M,Doney K,Schein OD

    更新日期:1997-10-01 00:00:00

  • Risk factors, clinical features, and outcomes of recurrent fungal keratitis after corneal transplantation.

    abstract:PURPOSE:To study the risk factors, clinical features, and treatment of recurrent fungal keratitis after corneal transplantation. DESIGN:Retrospective, interventional case series. PARTICIPANTS:Eight hundred ninety-nine patients (eyes) with fungal keratitis who underwent corneal transplantation at the Shandong Eye Inst...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2009.10.004

    authors: Shi W,Wang T,Xie L,Li S,Gao H,Liu J,Li H

    更新日期:2010-05-01 00:00:00

  • Aqueous misdirection after glaucoma drainage device implantation.

    abstract:OBJECTIVE:To describe the clinical presentation, outcome, and possible underlying mechanism of aqueous misdirection after glaucoma drainage device implantation. DESIGN:Retrospective, noncomparative, interventional case series. PARTICIPANTS:Ten eyes (five primary open-angle glaucoma, four chronic angle-closure glaucom...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/S0161-6420(99)00530-8

    authors: Greenfield DS,Tello C,Budenz DL,Liebmann JM,Ritch R

    更新日期:1999-05-01 00:00:00

  • Different Factors Associated with 2-Year Outcomes in Patients with Branch versus Central Retinal Vein Occlusion Treated with Ranibizumab.

    abstract:PURPOSE:To investigate characteristics associated with visual and anatomic outcomes in branch and central retinal vein occlusion (BRVO and CRVO) patients treated with ranibizumab. DESIGN:Post hoc analysis of patients with BRVO and CRVO from 2 multicenter clinical trials who completed month 12 of the HORIZON extension ...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ophtha.2019.07.018

    authors: Sophie R,Wang PW,Channa R,Quezada-Ruiz C,Clark A,Campochiaro PA

    更新日期:2019-12-01 00:00:00

  • A randomized, double-masked trial of topical ketorolac versus artificial tears for treatment of viral conjunctivitis.

    abstract:OBJECTIVE:To determine if topical ketorolac 0.5% relieves the symptoms and signs of viral conjunctivitis better than artificial tears. DESIGN:Randomized, controlled trial. PARTICIPANTS:One hundred seventeen patients with a clinical diagnosis of viral conjunctivitis were randomized to the treatment group or control gr...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0161-6420(00)00177-9

    authors: Shiuey Y,Ambati BK,Adamis AP

    更新日期:2000-08-01 00:00:00

  • The Impact of Systemic Factors on Clinical Response to Ranibizumab for Diabetic Macular Edema.

    abstract:PURPOSE:To evaluate the effect of systemic factors on best-corrected visual acuity (BCVA) achieved with ranibizumab (Lucentis; Genentech, Inc, South San Francisco, CA) for treatment of diabetic macular edema (DME) in the RIDE and RISE phase 3 studies. DESIGN:Exploratory, post hoc analysis of 2 randomized, double-maske...

    journal_title:Ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ophtha.2016.03.038

    authors: Singh RP,Habbu K,Ehlers JP,Lansang MC,Hill L,Stoilov I

    更新日期:2016-07-01 00:00:00

  • Genetic polymorphisms in DNA repair genes OGG1, APE1, XRCC1, and XPD and the risk of age-related cataract.

    abstract:PURPOSE:To analyze the association of the polymorphisms in 8-oxoguanine glycosylase-1 (OGG1), X-ray repair cross-complementing-1 (XRCC1), and AP endonuclease-1 (APE1) genes in the base excision repair pathway and xeroderma pigmentosum complementation group D (XPD) in the nucleotide excision repair pathway with the risk...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2011.11.004

    authors: Zhang Y,Zhang L,Song Z,Sun DL,Liu HR,Fu SB,Liu DR,Liu P

    更新日期:2012-05-01 00:00:00

  • Effect of focal lamina cribrosa defect on glaucomatous visual field progression.

    abstract:OBJECTIVE:To evaluate the association between focal, structural defects of the lamina cribrosa (LC) and glaucomatous visual field (VF) progression. DESIGN:Retrospective, observational study. PARTICIPANTS:A total of 169 patients with glaucoma (169 eyes) with a range of glaucomatous damage. METHODS:Serial horizontal a...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2014.02.017

    authors: Faridi OS,Park SC,Kabadi R,Su D,De Moraes CG,Liebmann JM,Ritch R

    更新日期:2014-08-01 00:00:00

  • Follow-up study of presumed ocular histoplasmosis syndrome.

    abstract::One hundred and sixty-two patients with presumed ocular histoplasmosis syndrome were evaluated. New macular scars not present on initial angiogram developed in 9% of eyes. The risk of developing a symptomatic macular lesion in eyes with asymptomatic macular scars was 23%. In eyes with peripapillary scarring, 3.8% deve...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(80)35226-3

    authors: Lewis ML,Van Newkirk MR,Gass JD

    更新日期:1980-05-01 00:00:00

  • Long-term outcome of keratolimbal allograft with or without penetrating keratoplasty for total limbal stem cell deficiency.

    abstract:PURPOSE:To evaluate the long-term outcome of ocular surface reconstruction, including keratolimbal allograft (KLAL) and amniotic membrane transplantation (AMT) with or without penetrating keratoplasty (PKP), in patients with nonambulatory vision secondary to total limbal stem cell deficiency (LSCD). DESIGN:Retrospecti...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(02)00960-0

    authors: Solomon A,Ellies P,Anderson DF,Touhami A,Grueterich M,Espana EM,Ti SE,Goto E,Feuer WJ,Tseng SC

    更新日期:2002-06-01 00:00:00

  • Outpatient cataract surgery: incident and procedural risk analysis do not support current clinical ophthalmology guidelines.

    abstract:OBJECTIVE:To evaluate whether an ophthalmologist-led, non-anesthesia-supported, limited monitoring pathway for phacoemulsification/intraocular lens cataract surgery, can be performed safely with only a medical emergency team providing support. DESIGN:Retrospective, observational, cohort study. PARTICIPANTS:All patien...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2014.08.030

    authors: Koolwijk J,Fick M,Selles C,Turgut G,Noordergraaf JI,Tukkers FS,Noordergraaf GJ

    更新日期:2015-02-01 00:00:00