Problems with parsimony in sequences of biased base composition.

abstract：:Runs of identical amino acids encoded by triplet repeats (homopolymers) are components of numerous proteins, yet their role is poorly understood. Large numbers of homopolymers are present in the Drosophila melanogaster mastermind (mam) protein surrounding several unique charged amino acid clusters. Comparison of mam s...

journal_title：Journal of molecular evolution

authors： Newfeld SJ,Schmid AT,Yedvobnick B

更新日期：1993-11-01 00:00:00

abstract：:Life is based on biopolymers that have the ability to replicate themselves. Here we consider how a self-replicating RNA system may have originated. We consider a reaction system in which polymerization is possible by the addition of an activated monomer to the end of a chain. We suppose that a small fraction of polyme...

journal_title：Journal of molecular evolution

authors： Wu M,Higgs PG

更新日期：2009-11-01 00:00:00

abstract：:Analysis of the expanded data set of Sibley and Ahlquist (1987) on primate phylogeny using a maximum likelihood mixed model analysis of variance method shows that there is significant evidence for resolving the Homo-Pan-Gorilla trifurcation in favor of a Homo-Pan clade. The resulting tree is close to that estimated by...

journal_title：Journal of molecular evolution

authors： Felsenstein J

更新日期：1987-01-01 00:00:00

abstract：:The availability of fast and accurate sequencing procedures along with the use of PCR has led to a proliferation of studies of variability at the molecular level in populations. Nevertheless, it is often impractical to examine long genomic stretches and a large number of individuals at the same time. In order to optim...

journal_title：Journal of molecular evolution

authors： Martin MJ,González-Candelas F,Sobrino F,Dopazo J

更新日期：1995-12-01 00:00:00

abstract：:Sequence comparisons of 14 distinct MHC class I cDNA clones isolated from species representing the three major taxonomic lineages of Felidae (domestic cat lineage, ocelot lineage, and pantherine lineage) revealed that feline MHC class I alleles have highly mosaic structures with short polymorphic sequence motifs that ...

journal_title：Journal of molecular evolution

authors： Yuhki N,O'Brien SJ

更新日期：1994-07-01 00:00:00

abstract：:The amino acid sequences of the largest subunits of the RNA polymerases I, II, and III from eukaryotes were compared with those of archaebacterial and eubacterial homologs, and their evolutionary relationships were analyzed in detail by a recently developed tree-making method, the likelihood method of protein phylogen...

journal_title：Journal of molecular evolution

authors： Iwabe N,Kuma K,Kishino H,Hasegawa M,Miyata T

更新日期：1991-01-01 00:00:00

abstract：:Ca(2+)/cation antiporter (CaCA) proteins are integral membrane proteins that transport Ca(2+) or other cations using the H(+) or Na(+) gradient generated by primary transporters. The CAX (for CAtion eXchanger) family is one of the five families that make up the CaCA superfamily. CAX genes have been found in bacteria, ...

journal_title：Journal of molecular evolution

authors： Shigaki T,Rees I,Nakhleh L,Hirschi KD

更新日期：2006-12-01 00:00:00

abstract：:Ubiquitin is remarkable for its ubiquitous distribution and its extreme protein sequence conservation. Ubiquitin genes comprise direct repeats of the ubiquitin coding unit with no spacers. The nucleotide sequences of several ubiquitin repeats from each of humans, chicken, Xenopus, Drosophila, barley, and yeast have re...

journal_title：Journal of molecular evolution

authors： Sharp PM,Li WH

更新日期：1987-01-01 00:00:00

abstract：:Previous studies have shown that pituitary growth hormone displays an episodic pattern of evolution, with a slow underlying evolutionary rate and occasional sustained bursts of rapid change. The present study establishes that pituitary prolactin shows a similar pattern. During much of tetrapod evolution the sequence o...

journal_title：Journal of molecular evolution

authors： Wallis M

更新日期：2000-05-01 00:00:00

abstract：:Microsatellite DNA sequences have become the dominant source of nuclear genetic markers for most applications. It is important to investigate the basis of variation between alleles and to know if current assumptions about the mechanisms of microsatellite mutation (that is to say, variations involving simple changes in...

journal_title：Journal of molecular evolution

authors： Grimaldi MC,Crouau-Roy B

更新日期：1997-03-01 00:00:00

abstract：:We have implemented a routine procedure for screening protein sequences for evidence of intragenic duplications. We tested 163 protein sequences representing 116 superfamilies of unrelated proteins. Twenty superfamilies contain proteins with internal gene duplications. The intragenic duplications detected can be divid...

journal_title：Journal of molecular evolution

authors： Barker WC,Ketcham LK,Dayhoff MO

更新日期：1978-02-21 00:00:00

abstract：:We outline a method for estimating quantitatively the influence of point mutations and selection on the frequencies of codons and amino acids. We show how the mutation rate, i.e., the rate of amino acid replacement due to point mutation, can be affected by the codon usage as well as by the rates of the involved base e...

journal_title：Journal of molecular evolution

authors： Frömmel C,Holzhütter HG

更新日期：1984-01-01 00:00:00

abstract：:HMG boxes were initially identified as DNA-binding domains of the human RNA polymerase I (pol I) transcription factor hUBF and the animal high-mobility-group (HMG) protein family HMG1. Since then, numerous sequences of HMG-box-containing HMG proteins and other DNA-binding proteins from several species have become avai...

journal_title：Journal of molecular evolution

authors： Griess EA,Rensing SA,Grasser KD,Maier UG,Feix G

更新日期：1993-08-01 00:00:00

abstract：:Males of three inbred lines of Drosophila melanogaster were heat-shocked 90 min at 37 degrees C. The progenies from treated and untreated males mated with untreated females of the same line were checked for their chromosomal insertion patterns of various mobile elements by either in situ hybridization or Southern blot...

journal_title：Journal of molecular evolution

authors： Arnault C,Biémont C

更新日期：1989-05-01 00:00:00

abstract：:Two competing effects at two vastly different scales may explain collagen's current translation length. The necessity to have long molecules for maintaining mechanical integrity at the organism and supraorganism scales may be limited by the need to have small molecules capable of robust self-assembly at the nanoscale....

journal_title：Journal of molecular evolution

authors： Layton BE,D'Souza AJ,Dampier W,Zeiger A,Sabur A,Jean-Charles J

更新日期：2008-06-01 00:00:00

abstract：:Sequences were obtained from five species of rodents that are orthologous to an H2a histone pseudogene from Mus musculus. The pseudogene is part of the cluster of replication-dependent histone genes found on Mus musculus chromosome 13. Comparative analysis of these five sequences together with the previously published...

journal_title：Journal of molecular evolution

authors： DeBry RW

更新日期：1998-03-01 00:00:00

abstract：:A few years ago we presented a stationary Markov model of gene evolution according to which only homologous genes from not too divergent species obeying the condition of being stationary may behave as reliable molecular clocks. A compartmentalized model of the nuclear genome in which the genes are distributed in compa...

journal_title：Journal of molecular evolution

authors： Saccone C,Pesole G,Preparata G

更新日期：1989-11-01 00:00:00

abstract：:tRNA with a terminal UCCA-3' forms a structure in which the 3'-sequence folds back. The adenine of glycyl-AMP can base-pair with the uridine of the UCCA-3' region, which places the glycine residue in close proximity to the 3'-terminal adenosine of tRNA, possibly enabling the transfer of glycine from glycyl-AMP to tRNA...

journal_title：Journal of molecular evolution

authors： Tamura K

更新日期：2015-10-01 00:00:00

abstract：:Complete chloroplast 23S rRNA and psbA genes from five peridinin-containing dinoflagellates (Heterocapsa pygmaea, Heterocapsa niei, Heterocapsa rotun-data, Amphidinium carterae, and Protoceratium reticulatum) were amplified by PCR and sequenced; partial sequences were obtained from Thoracosphaera heimii and Scrippsiel...

journal_title：Journal of molecular evolution

authors： Zhang Z,Green BR,Cavalier-Smith T

更新日期：2000-07-01 00:00:00

abstract：:Leucine-rich repeat receptor-like kinases (LRR RLKs) comprise the largest group within the plant receptor-like kinase (RLK) superfamily, and the Arabidopsis genome alone contains over 200 LRR RLK genes. Although there is clear evidence for diverse roles played by individual LRR RLK genes in Arabidopsis growth and deve...

journal_title：Journal of molecular evolution

authors： Zhang XS,Choi JH,Heinz J,Chetty CS

更新日期：2006-11-01 00:00:00

abstract：:Molecular characteristics, especially 18S rDNA sequences, may be of great value for the study of bivalve evolution and its numerous morphological convergencies once the reliability of these data can be evaluated. The analysis of 11 published complete molluscan sequences and two new ones, Arca noae and Atrina pectinata...

journal_title：Journal of molecular evolution

authors： Steiner G,Müller M

更新日期：1996-07-01 00:00:00

abstract：:Phylogenetic relationships of nematodes, nematomorphs, kinorhynchs, priapulids, and some other major groups of invertebrates were studied by 18S rRNA gene sequencing. Kinorhynchs and priapulids form the monophyletic Cephalorhyncha clade that is the closest to the coelomate animals. When phylogenetic trees were generat...

journal_title：Journal of molecular evolution

authors： Aleshin VV,Milyutina IA,Kedrova OS,Vladychenskaya NS,Petrov NB

更新日期：1998-11-01 00:00:00

abstract：:We have further characterized the Asian genotypes (Types 2 and 7) and subtypes of JC virus (JCV). Urine samples from 224 individuals with Han and Mongolian populations were collected in five regions in eastern China: Kunming, Chengdu, Shenyang, Chifeng, and Manzhouli. Also, 99 urine samples were collected from coastal...

journal_title：Journal of molecular evolution

authors： Cui X,Wang JC,Deckhut A,Joseph BC,Eberwein P,Cubitt CL,Ryschkewitsch CF,Agostini HT,Stoner GL

更新日期：2004-05-01 00:00:00

abstract：:Cosmochemical considerations suggest various potential sources for the accumulation of organic matter on Mars. However the Viking Molecular Analysis did not indicate any indigenous organic compounds on the surface of Mars. Their disappearance from the top layer is most likely caused by the combined action of the high ...

journal_title：Journal of molecular evolution

authors： Oró J,Holzer G

更新日期：1979-12-01 00:00:00

abstract：:The PIGSFEAST (PF) exon of the Drosophila dumpy gene is undergoing concerted evolution by the process of unequal crossing over. We have developed a long-range PCR-based assay to amplify the approximately 12 kb long exon which contains variable numbers of 303 or 306 nt long repeats in a tandem array. We applied this pr...

journal_title：Journal of molecular evolution

authors： Carmon A,Larson M,Wayne M,MacIntyre R

更新日期：2010-03-01 00:00:00

abstract：:Two catalytic functions were required, minimally, for the appearance of DNA in evolution: a ribonucleotide reductase (RNR) and a reverse transcriptase (RT). If one accepts the explanatory strength of the RNA world model, it is clear that DNA molecules arose in the RNA world at some stage during the early evolution of ...

journal_title：Journal of molecular evolution

authors： León PE

更新日期：1998-08-01 00:00:00

abstract：:One crucial event during evolution to multicellularity was the development of either direct cell-cell contact or indirect interaction via extracellular matrix (ECM) molecules. The identification of those polypeptides provides conclusive data on the phylogenetic relationship of metazoan phyla and helps us to understand...

journal_title：Journal of molecular evolution

authors： Schütze J,Skorokhod A,Müller IM,Müller WE

更新日期：2001-10-01 00:00:00

abstract：:The previously given systems-theoretic model for the synthesis of optical antipodes (AD and AL) in strongly asymmetric yield, which shows mono-bistable behaviour depending on the degree of "openess" of the chemical reaction system is reconsidered for two equal compartments (subscripts 1 and 2 on A) with coupling by di...

journal_title：Journal of molecular evolution

authors： Seelig FF,Zielke R

更新日期：1975-10-29 00:00:00

abstract：:The phylogeny of the creatine kinase (CK, EC 2.7.3.2) isozyme loci and their differential tissue expressions were determined for representatives of 65 families of vertebrates, with emphasis on the fishes. The transition from the single creatine kinase locus, characteristic of certain echinoderms, to the two creatine k...

journal_title：Journal of molecular evolution

authors： Fisher SE,Whitt GS

更新日期：1978-10-27 00:00:00

abstract：:EcoRI restriction of the B. nigra rDNA recombinants, isolated from a lambda genomic library, showed that the 3.9-kb fragment corresponded to the Intergenic Spacer (IGS), which was sequenced and found to be 3,928 bp in size. Sequence and dot-matrix analyses showed that the organization of the B. nigra rDNA IGS was typi...

journal_title：Journal of molecular evolution

authors： Bhatia S,Singh Negi M,Lakshmikumaran M

更新日期：1996-11-01 00:00:00