Abstract:
:tRNA with a terminal UCCA-3' forms a structure in which the 3'-sequence folds back. The adenine of glycyl-AMP can base-pair with the uridine of the UCCA-3' region, which places the glycine residue in close proximity to the 3'-terminal adenosine of tRNA, possibly enabling the transfer of glycine from glycyl-AMP to tRNA. Thus, the UCCA-3'-containing tRNA (as seen in eubacterial tRNA(Gly)s) would possess an intrinsic property of glycylation by glycyl-AMP. This model provides a new perspective on the origins of the glycine assignment in the genetic code, beyond the "frozen accident" hypothesis.
journal_name
J Mol Evoljournal_title
Journal of molecular evolutionauthors
Tamura Kdoi
10.1007/s00239-015-9694-8subject
Has Abstractpub_date
2015-10-01 00:00:00pages
69-71issue
3-4eissn
0022-2844issn
1432-1432pii
10.1007/s00239-015-9694-8journal_volume
81pub_type
信件abstract::Studies so far have correlated the variation in the composition of snake venoms with the target prey population and snake's diet. Here we present the first example of an alternative evolutionary link between venom composition and dietary adaptation of snakes. We describe a dinucleotide deletion in the only three finge...
journal_title:Journal of molecular evolution
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journal_title:Journal of molecular evolution
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journal_title:Journal of molecular evolution
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journal_title:Journal of molecular evolution
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doi:10.1007/s00239-004-2596-9
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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journal_title:Journal of molecular evolution
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更新日期:2001-02-01 00:00:00
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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更新日期:2003-12-01 00:00:00
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-009-9276-8
更新日期:2009-11-01 00:00:00
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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更新日期:1997-09-01 00:00:00
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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journal_title:Journal of molecular evolution
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更新日期:2002-05-01 00:00:00
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journal_title:Journal of molecular evolution
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更新日期:2002-04-01 00:00:00
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doi:10.1007/s00239-007-9062-4
更新日期:2008-01-01 00:00:00
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journal_title:Journal of molecular evolution
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更新日期:1996-06-01 00:00:00
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journal_title:Journal of molecular evolution
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journal_title:Journal of molecular evolution
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
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abstract::Insertions and deletions of entire codons have recently been discovered as a mechanism by which B cells, in addition to conventional base substitution, evolve the antibodies produced by their immunoglobulin genes. These events frequently seem to involve repetitive sequence motifs in the antibody-encoding genes, and it...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
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abstract::Alu elements are not distributed homogeneously throughout the human genome: old elements are preferentially found in the GC-rich parts of the genome, while young Alus are more often found in the GC-poor parts of the genome. The process giving rise to this differential distribution remains poorly understood. Here we in...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
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abstract::A 2550-bp portion of the mitochondrial genome of a Demosponge, genus Tetilla, was amplified from whole genomic DNA extract and sequenced. The sequence was found to code for the 3' end of the 16S rRNA gene, cytochrome c oxidase subunit II, a lysine tRNA, ATPase subunit 8, and a 5' portion of ATPase subunit 6. The Porif...
journal_title:Journal of molecular evolution
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abstract::In this study, the molecular population genetics of the orangutan's alpha-2 globin (HBA2) gene were investigated in order to test for the action of natural selection. Haplotypes from 28 orangutan chromosomes were collected from a 1.46-kilobase region of the alpha-2 globin locus. While many aspects of the data were con...
journal_title:Journal of molecular evolution
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更新日期:2005-03-01 00:00:00
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journal_title:Journal of molecular evolution
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