Abstract：
:The previously given systems-theoretic model for the synthesis of optical antipodes (AD and AL) in strongly asymmetric yield, which shows mono-bistable behaviour depending on the degree of "openess" of the chemical reaction system is reconsidered for two equal compartments (subscripts 1 and 2 on A) with coupling by diffusion. In this configuration three threshold values, j1, is less than j2 is less than j3, for the influx j of the common precursor substance appear. For j is less than j1 only one steady state (s.s.) with no optical activity (ADi = ALi, i-1;2) and equal distribution of the antipodes in both compartments (AD1 = AD2, AL1 = AL2) exists. For j is greater than j 1, this totally symmetric s.s. becomes unstable and a pair of s.s. with optical activity (AD1 is less than AL1, AD2 is less than AL2 or AD1 is greater than AL1, AD2 is greater than AL2) but no spatial asymmetry emerges (parallel flipping), i.e. both compartments be8have as a whole, showing a preponderance of either the D- or the L-form. For j is greater than j2 in addition two new s.s. are possible with antiparallel flipping (AD1 is less than AL1, AD2 is greater than AL2 or AD1 is greater than AL1, AD2 is less than AL2), i.e. in one compartment the D-form has the majority and in the other one the L-form, but these are stable only beyond a third threshold value j3. A third thinkable pair with no optical activity, but different sum concentrations in both cells, does not exist in this special circuitry, but can be obtained in a slightly changed arrangement. So for j is greater than j2, 5 different (4 stable, 1 unstable) s.s., exist for the same set of parameters, one of which is chosen by the system.
journal_name
J Mol Evoljournal_title
Journal of molecular evolutionauthors
Seelig FF,Zielke Rdoi
10.1007/BF01732292keywords:
subject
Has Abstractpub_date
1975-10-29 00:00:00pages
117-29issue
2eissn
0022-2844issn
1432-1432journal_volume
6pub_type
杂志文章abstract：:Restriction modification (RM) systems serve to protect bacteria against bacteriophages. They comprise a restriction endonuclease activity that specifically cleaves DNA and a corresponding methyltransferase activity that specifically methylates the DNA, thereby protecting it from cleavage. Such systems are very common ...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02198833
更新日期：1996-02-01 00:00:00
abstract：:This study investigated the evolution of a transition metal ion-binding cluster ([H--X--X--X--H](n); Tx) in the alternatively spliced NH(2)-terminal variable region of avian pectoral muscle troponin T (TnT). Encoded by avian fast skeletal muscle TnT-specific P exons, Tx-like structures were expressed in the breast mus...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s002390010139
更新日期：2001-02-01 00:00:00
abstract：:Segmental pattern in Drosophila melanogaster is set up via a set of cell-cell interactions mediated by the products of the segment polarity genes. Among these is the armadillo gene, whose product seems to be required for the reception of an intercellular signal encoded by the wingless gene. As part of our effort to re...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00160477
更新日期：1993-03-01 00:00:00
abstract：:Studies so far have correlated the variation in the composition of snake venoms with the target prey population and snake's diet. Here we present the first example of an alternative evolutionary link between venom composition and dietary adaptation of snakes. We describe a dinucleotide deletion in the only three finge...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-004-0138-0
更新日期：2005-01-01 00:00:00
abstract：:In studies of molecular evolution, the assumption that protein evolution is reversible has often been made, but rarely tested. Here we use a large set of orthologous murid protein coding sequences to perform a simple test of reversibility, and find no evidence to reject the assumption of reversibility in protein evolu...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s002390010176
更新日期：2001-05-01 00:00:00
abstract：:Previous studies have shown that pituitary growth hormone displays an episodic pattern of evolution, with a slow underlying evolutionary rate and occasional sustained bursts of rapid change. The present study establishes that pituitary prolactin shows a similar pattern. During much of tetrapod evolution the sequence o...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s002390010049
更新日期：2000-05-01 00:00:00
abstract：:While studies of the evolutionary histories of protein families are commonplace, little is known on noncoding RNAs beyond microRNAs and some snoRNAs. Here we investigate in detail the evolutionary history of the nine spliceosomal snRNA families (U1, U2, U4, U5, U6, U11, U12, U4atac, and U6atac) across the completely o...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-008-9149-6
更新日期：2008-12-01 00:00:00
abstract：:Comparisons of the sequence divergence of three species of Hawaiian Drosophila have been made by hybridization of single-copy tracer DNA of each of the species with driver DNA from each species, and measurement of the average melting temperature (Tma) in a chaotropic solvent (2.4 M tetraethylammonium chloride) which m...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF01734358
更新日期：1981-01-01 00:00:00
abstract：:The beta-globin gene cluster of Wistar rat was extensively cloned and the embryonic genes were mapped and sequenced. Four overlapping lambda Dash recombinant clones cover about 31 kb and contain four nonadult beta-globin genes, 5'-epsilon1-gamma1-gamma2-psigamma3-3'. The epsilon1 and gamma2 are active genes, since the...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/pl00006525
更新日期：1999-07-01 00:00:00
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journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00175814
更新日期：1995-11-01 00:00:00
abstract：:The 70-kDa heat-shock protein (HSP70) constitutes the most conserved protein present in all organisms that is known to date. Based on global alignment of HSP70 sequences from organisms representing all three domains, numerous sequence signatures that are specific for prokaryotic and eukaryotic homologs have been ident...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00182743
更新日期：1993-12-01 00:00:00
abstract：:Phylogenetic relationships of 25 mammalian species representing 17 of the 18 eutherian orders were examined using DNA sequences from a 1.2-kb region of the 5' end of exon 1 of the single-copy nuclear gene known as interphotoreceptor retinoid binding protein (IRBP). A wide variety of methods of analysis of the DNA sequ...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02337352
更新日期：1996-08-01 00:00:00
abstract：:The internal transcribed spacer region (ITS) of the nuclear rDNA cistron represents the barcoding locus for Fungi. Intragenomic variation of this multicopy gene can interfere with accurate phylogenetic reconstruction of biological entities. We investigated the amount and nature of this variation for the lichenized fun...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-013-9603-y
更新日期：2014-02-01 00:00:00
abstract：:Nuclear DNA contents were estimated by microdensitometry in five species of Akodon rodents: Arodon molinae, A. dolores, A. mollis, A. azarae, Bolomys obscurus) and in three chromosomal varieties of A. molinae (2n = 42; 2n = 43, 2n = 22). The data obtained showed that the species with the highest DNA content was B. obs...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02101640
更新日期：1983-01-01 00:00:00
abstract：:The level reached by the optimization of the polarity distances during the evolution of the genetic code was investigated. The results, although not conclusive, indicate that this optimization level is higher than the data reported in the literature. The results seem compatible with the reaching of an evolutionary min...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02103616
更新日期：1989-10-01 00:00:00
abstract：:The sequence of a cloned Anopheles stephensi gene showed 72% inferred amino acid identity with Drosophila melanogaster Dox-A2 and 93% with its putative ortholog in Anopheles gambiae. Dox-A2 is the reported but herein disputed structural locus for diphenol oxidase A2. Database searches identified Dox-A2 related gene se...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s002390010053
更新日期：2000-06-01 00:00:00
abstract：:Simple sequence repeats (SSRs) in DNA sequences are tandem iterations of a single nucleotide or a short oligonucleotide. SSRs are subject to slipped-strand mutations and a common source of phase variation in bacteria and antigenic variation in pathogens. Significantly long SSRs are generally rare in prokaryotic genome...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-008-9166-5
更新日期：2008-11-01 00:00:00
abstract：:RNA has a myriad of biological roles in contemporary life. We use the RNA paradigm for genotype-phenotype mappings to study the evolution of multiple coding in dependence to mutation rates. We study three different one-to-many genotype-phenotype mappings which have the potential to encode the information for multiple ...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-014-9648-6
更新日期：2014-12-01 00:00:00
abstract：:Cot and chemical analysis show that the haploid genome size of Thermobia domestica is 3-4x10(9) nucleotide pairs. Of this DNA 33% is single copy sequences and 67% is repetitive sequences. The repetitive sequences are predominantly 300 nucleotides in length and are interspersed among the single copy sequences in a shor...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF01733135
更新日期：1980-08-01 00:00:00
abstract：:The periodic protein collagen is of special interest for the study of the relationship which exists between the structure of a protein and that of its mRNA, because oligopeptides containing glycine, proline (hydroxyproline) and alanine occur with great frequency in it. Collagen is particularly rich in these amino acid...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF01739101
更新日期：1976-08-03 00:00:00
abstract：:A model of nucleotide substitution that allows the transition/transversion rate bias to vary across sites was constructed. We examined the fit of this model using likelihood-ratio tests by analyzing 13 protein coding genes and 1 pseudogene. Likelihood-ratio testing indicated that a model that allows variation in the t...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/pl00006448
更新日期：1999-01-01 00:00:00
abstract：:Scorpion venom toxins were systematically classified according to amino acid composition, insertion/deletion events and sequence. The significance of each comparison method and its outcome is discussed in relation to known immunological and structural properties. A general classification of the toxins is proposed that...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02257372
更新日期：1984-01-01 00:00:00
abstract：:The nearly neutral theory attributes most nucleotide substitution and polymorphism to genetic drift acting on weakly selected mutants, and assumes that the selection coefficients for these mutants are drawn from a continuous distribution. This means that parameter estimation can require numerical integration, and this...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-008-9146-9
更新日期：2008-10-01 00:00:00
abstract：:Factors involved in the selection of the 20 protein L-alpha-amino acids during chemical evolution and the early stages of Darwinian evolution are discussed. The selection is considered on the basis of the availability in the primitive ocean, function in proteins, the stability of the amino acid and its peptides, stabi...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF01795749
更新日期：1981-01-01 00:00:00
abstract：:Cyclooxygenase (COX) enzymatically converts arachidonic acid into prostaglandin G/H in animals and has importance during pregnancy, digestion, and other physiological functions in mammals. COX genes have mainly been described from vertebrates, where gene duplications are common, but few studies have examined COX in in...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-015-9670-3
更新日期：2015-04-01 00:00:00
abstract：:Seven new Italian and two new British HTLV-II isolates were obtained from injecting drug users and the entire long terminal repeat (LTR) region was sequenced. Restriction analysis showed that all the Italian isolates are of the IIb subtype, whereas the British isolates are of the IIa subtype. To understand whether the...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/pl00006340
更新日期：1998-05-01 00:00:00
abstract：:DNA methylation is one of the many hypotheses proposed to explain the observed deficiency in CpG dinucleotides in a variety of genomes covering a wide taxonomic distribution. Recent studies challenged the methylation hypothesis on empirical grounds. First, it cannot explain why the Mycoplasma genitalium genome exhibit...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-003-0003-6
更新日期：2003-01-01 00:00:00
abstract：:The transposable element mariner occurs widely in the melanogaster species group of Drosophila. However, in drosophilids outside of the melanogaster species group, sequences showing strong DNA hybridization with mariner are found only in the genus Zaprionus. The mariner sequence obtained from Zaprionus tuberculatus is...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02102804
更新日期：1991-12-01 00:00:00
abstract：:Multiple phospholipase A2 (PLA2) isoenzymes found in a single snake venom induce a variety of pharmacological effects. These multiple forms are formed by gene duplication and accelerated evolution of exons. We examined the amino acid sequences of 127 snake venom PLA2 enzymes and their homologues to study in which loca...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/pl00006450
更新日期：1999-02-01 00:00:00
abstract：:Eight new examples of retrotransposons of the Gypsy/Ty3 class have been identified in marine species. A 525-nt pol gene-coding region was amplified using degenerate primers from highly conserved regions and has extended the range of recognition of Gypsy/Ty3 far beyond those previously known. The following matrix shows...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00166592
更新日期：1995-01-01 00:00:00
