当前位置： SCI文献检索 > FERTILITY AND STERILITY期刊下所有文献 > Prevalence of Y chromosome microdeletions in oligospermic and azoospermic candidates for intracytoplasmic sperm injection.

Prevalence of Y chromosome microdeletions in oligospermic and azoospermic candidates for intracytoplasmic sperm injection.

Abstract：

OBJECTIVE:To determine the prevalence and type of Y chromosome microdeletions in 136 consecutively seen intracytoplasmic sperm injection (ICSI) candidates and in 50 consecutively seen azoospermic men attending an infertility clinic. DESIGN:Controlled clinical study. SETTING:Genetics laboratory and infertility clinic at a University hospital. PATIENT(S):One hundred eighty-six men who were seen at an infertility clinic and who were referred to a genetics counseling service for genetic assessment before ICSI. INTERVENTION(S):Collection of semen and blood samples. MAIN OUTCOME MEASURE(S):Semen analysis; serum FSH, LH, and T levels; karyotype analysis; and presence or absence of several single tagged site markers along the Y chromosome (sY274, sY238, sY276, sY84, sY102, sY143, sY153, sY254, sY269, sY202, sY158, sY160). RESULT(S):Yq chromosome microdeletions were detected in 10 (5.4%) of 186 consecutively seen ICSI candidates. The number of microdeletions was much higher in azoospermic patients (16%; 8 of 50) than in oligospermic patients (1.5%; 2 of 136). Two of the azoospermic patients with a Yq microdeletion also had sex chromosome aneuploidy mosaicism. No microdeletions were detected in 100 consecutively seen fathers who were included as controls. CONCLUSION(S):The prevalence of Yq microdeletions in the azoospermic group was much higher than in the oligospermic group and was consistent with the prevalence of Yq microdeletions detected in other series of azoospermic men in different geographic areas. All Yq microdeletions found in our patients belong to the AZFc region, indicating that microdeletions of the AZFa and AZFb regions are infrequent among oligospermic ICSI candidates or azoospermic males in our population.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Oliva R,Margarit E,Ballescá JL,Carrió A,Sánchez A,Milà M,Jiménez L,Alvarez-Vijande JR,Ballesta F

doi

10.1016/s0015-0282(98)00195-2

subject

Has Abstract

pub_date

1998-09-01 00:00:00

pages

506-10

issue

3

eissn

0015-0282

issn

1556-5653

pii

S0015028298001952

journal_volume

70

pub_type

临床试验,杂志文章

相关文献

FERTILITY AND STERILITY文献大全
  • Partnered sexual activity moderates menstrual cycle-related changes in inflammation markers in healthy women: an exploratory observational study.

    abstract：OBJECTIVE:To examine differences in inflammation markers in sexually active versus abstinent women and observe changes in inflammation markers across the menstrual cycle. Cycle-related immune fluctuations may have evolved to reduce interference with conception. If so, reproductively active (i.e., sexually active) women...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2016.11.010

    authors： Lorenz TK,Demas GE,Heiman JR

    更新日期：2017-03-01 00:00:00

  • Professional self-regulation for preimplantation genetic diagnosis: experience of the American Society for Reproductive Medicine and other professional societies.

    abstract：:Professional societies that are stakeholders in preimplantation genetic diagnosis have democratically elected officers and favor self-regulation. Their practice guidelines are cognizant of societal needs and allow for introduction of new technologies. These societies have demonstrated the ability for professional self...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2006.02.072

    authors： Simpson JL,Rebar RW,Carson SA

    更新日期：2006-06-01 00:00:00

  • Carbohydrate and lipid studies in women using the progesterone intrauterine device for one year.

    abstract：:Carbohydrate and lipid metabolism was evaluated in 31 women before and after 1 year's use of a progesterone-releasing intrauterine device. The studies involved measuring blood glucose and plasma insulin levels during a 3-hour oral glucose tolerance test and also measuring fasting cholesterol and triglyceride levels. T...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)43932-4

    authors： Spellacy WN,Buhi WC,Birk SA

    更新日期：1979-04-01 00:00:00

  • Endometrial integrin expression in women exposed to diethylstilbestrol in utero.

    abstract：OBJECTIVE:To determine if the endometrium of women exposed in utero to diethylstilbestrol (DES) demonstrates altered integrin expression compared with normal fertile controls. DESIGN:Case control study. Expression of eight integrins in 15 luteal phase endometrial biopsies from DES-exposed women were compared with 17 b...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：

    authors： Castelbaum AJ,Sawin SW,Bellardo LJ,Lessey BA

    更新日期：1995-06-01 00:00:00

  • Free sex steroid and sex hormone-binding globulin levels in oligozoospermic men with varicoceles.

    abstract：OBJECTIVE:To measure free T, free E2, and sex hormone-binding globulin (SHBG) levels in oligozoospermic men with varicoceles. DESIGN:Retrospective study. PATIENTS:Sixty-four infertile patients with varicoceles. SETTING:A university-based tertiary care referral center. INTERVENTIONS:Assessment of seminal cellular ch...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：

    authors： Hudson RW

    更新日期：1996-08-01 00:00:00

  • Accumulation of nicotine in the uterine fluid of the six-day pregnant rabbit.

    abstract：:In 6-day pregnant New Zealand White rabbits dosed intravenously with 3H-nicotine, the 3H-activity in the uterine fluid was approximately 5 to 11 times greater than that in the plasma at the corresponding times; 3H-nicotine itself accounted for most of this radioactivity. Dichlorodiphenyltrichloroethane (DDT) also accu...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：

    authors： McLachlan JA,Dames NM,Sieber SM,Fabro S

    更新日期：1976-10-01 00:00:00

  • Society for assisted reproductive technology position statement on donor suitability of recipients of smallpox vaccine (vaccinia virus).

    abstract：:Although there is presently no definitive evidence linking vaccinia virus transmission through reproductive cells, SART/ASRM accordingly recommends that assisted reproductive technology (ART) practitioners consider deferring donors who have recently received smallpox vaccine or contracted symptomatic vaccinia virus in...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2003.12.013

    authors： Practice Committee of the American Society for Reproductive Medicine.,Society for Assisted Reproductive Technology.

    更新日期：2004-04-01 00:00:00

  • Pregnancy outcomes decline with increasing body mass index: analysis of 239,127 fresh autologous in vitro fertilization cycles from the 2008-2010 Society for Assisted Reproductive Technology registry.

    abstract：OBJECTIVE:To examine the effect of body mass index (BMI) on IVF outcomes in fresh autologous cycles. DESIGN:Retrospective cohort study. SETTING:Not applicable. PATIENT(S):A total of 239,127 fresh IVF cycles from the 2008-2010 Society for Assisted Reproductive Technology registry were stratified into cohorts based on...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2015.11.008

    authors： Provost MP,Acharya KS,Acharya CR,Yeh JS,Steward RG,Eaton JL,Goldfarb JM,Muasher SJ

    更新日期：2016-03-01 00:00:00

  • The effect of centchroman on serum luteinizing hormone in normal males.

    abstract：:Elevation of serum luteinizing hormone levels was observed in five normal male volunteers while they were taking Centchroman. This effect resembles that of clomiphene and suggests a new biologic potential of Centchroman. ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)41785-1

    authors： Vaidya RA,Sheth A,Meherji P,Joshi L,Devi PK

    更新日期：1976-04-01 00:00:00

  • Transvaginal ultrasonography combined with water-contrast in the rectum in the diagnosis of rectovaginal endometriosis infiltrating the bowel.

    abstract：:This prospective study evaluated the efficacy of transvaginal ultrasonography combined with water-contrast in the rectum (RWC-TVS) in the diagnosis of rectal infiltration in 35 women with rectovaginal endometriosis; ultrasonographic findings were compared with surgery and histology. The sensitivity of RWC-TVS in ident...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2007.07.1336

    authors： Menada MV,Remorgida V,Abbamonte LH,Fulcheri E,Ragni N,Ferrero S

    更新日期：2008-03-01 00:00:00

  • The basal body temperature chart in artificial insemination by donor pregnancy cycles.

    abstract：:The basal body temperature (BBT) charts in pregnancy cycles of 110 consecutive women who became pregnant by a single heterologous insemination were studied. The occurrence of ovulation was proved by the pregnancies in each case. All of these pregnancy charts showed a biphasic pattern, and most followed one of three st...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)46577-5

    authors： Newill RG,Katz M

    更新日期：1982-10-01 00:00:00

  • Blastocyst formation, pregnancy, and birth derived from human oocytes cryopreserved for 5 years.

    abstract：OBJECTIVE:To report a live birth after the transfer of a single blastocyst derived from a human oocyte cryopreserved for 5 years. DESIGN:Case report. SETTING:Private assisted reproduction center. PATIENT(S):A 39-year-old woman with tubal infertility and her partner with male-related infertility. INTERVENTION(S):Ooc...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2008.01.106

    authors： Parmegiani L,Fabbri R,Cognigni GE,Bernardi S,Pocognoli P,Filicori M

    更新日期：2008-11-01 00:00:00

  • Deoxyribonucleic acid flow cytometry of germ cells in the investigatin of male infertility.

    abstract：:DNA flow cytometry was applied to fine-needle aspiration biopsy specimens from the testes of 20 oligospermic or azoospermic men under investigation for infertility. All aspirations gave sufficient material for DNA flow cytometry, and no complications occurred after aspiration. In both groups many DNA patterns deviated...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)45014-4

    authors： Clausen OP,Abyholm T

    更新日期：1980-10-01 00:00:00

  • Effects of interstitial fallopian tube polyps on isthmic tubal diameter.

    abstract：OBJECTIVE:To study the apparent association between interstitial fallopian tube polyps and isthmic tubal dilatation. DESIGN:Retrospective clinical study. SETTING:Tertiary academic medical center. PATIENT(S):Sixty-five patients with normal hysterosalpingograms and 40 patients with interstitial tubal polyps (25 unilat...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2004.10.049

    authors： Brubaker LM,Clark RL

    更新日期：2005-05-01 00:00:00

  • "Crushed glass" appearance of particles observed in roentgenograms after hysterosalpingography as an indicator of pelvic abnormalities.

    abstract：OBJECTIVE:To evaluate the diagnostic value of the crushed glass appearance of particles observed on roentgenogram after hysterosalpingography in patients with pelvic abnormalities. DESIGN:Retrospective study of 32 patients whose roentgenogram had particles with a crushed glass appearance and 16 patients without crushe...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(97)00415-9

    authors： Sawada T,Kuroki J,Yoshimura Y,Kawakami S

    更新日期：1997-12-01 00:00:00

  • Flow cytometry provides rapid and highly accurate detection of antisperm antibodies.

    abstract：OBJECTIVE:Immunobead testing (IBT), the current standard for antisperm antibody detection, is time consuming and somewhat subjective. To overcome these limitations and maintain accuracy, we studied an immunofluorescent assay using flow cytometry. DESIGN:A validation study comparing flow cytometry to IBT in the detecti...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：

    authors： Ke RW,Dockter ME,Majumdar G,Buster JE,Carson SA

    更新日期：1995-04-01 00:00:00

  • Comparison of three computer methods of sperm head analysis.

    abstract：OBJECTIVE:Analysis of sperm heads using three different computer morphometrical tools and experimental conditions to find a more reliable and secure strategy among them. DESIGN:Controlled experiments on sperm morphology analysis from volunteers. SETTING:Laboratory of microscopy and imaging processing. PATIENT(S):Ten...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(03)00978-6

    authors： Goulart AR,de Alencar Hausen M,Monteiro-Leal LH

    更新日期：2003-09-01 00:00:00

  • Utilization of fertility-related services in the United States.

    abstract：:To describe trends in the types of fertility-related medical services that women and/or their partners have received while trying to become pregnant, the author analyzed data from women aged 20-44 years who participated in the 2002 National Survey of Family Growth. Advice (74%) and infertility testing (59%) were the m...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2007.10.034

    authors： Vahratian A

    更新日期：2008-10-01 00:00:00

  • A prospective randomized controlled trial comparing two embryo transfer catheters in an ART program.

    abstract：OBJECTIVE:To compare the performance of the Cook Sydney IVF (SIVF) embryo transfer (ET) catheter and the Edwards-Wallace (EW) ET catheter. DESIGN:Prospective randomized controlled clinical trial with an intention-to-treat analysis. SETTING:Two-center study. PATIENT(S):Four hundred consecutive women <40 years undergo...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.fertnstert.2007.06.085

    authors： Saldeen P,Abou-Setta AM,Bergh T,Sundström P,Holte J

    更新日期：2008-09-01 00:00:00

  • Assessing the true incidence of mosaicism in preimplantation embryos.

    abstract：:Modern technologies applied to the field of preimplantation genetic diagnosis for aneuploidy screening (PGD-A) have improved the ability to identify the presence of mosaicism. Consequently, new questions can now be addressed regarding the potential impact of embryo mosaicism on diagnosis accuracy and the feasibility o...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,评审

    doi：10.1016/j.fertnstert.2017.03.019

    authors： Vera-Rodriguez M,Rubio C

    更新日期：2017-05-01 00:00:00

  • Tests of prolactin secretion in the diagnosis of hyperprolactinemic states: nomifensine and domperidone.

    abstract：:Forty-one subjects with hyperprolactinemia underwent testing on separate occasions with nomifensine, an indirectly acting dopamine agonist, and domperidone, a dopamine receptor-blocking agent. Nomifensine (200 mg orally) did not significantly modify plasma levels of prolactin (PRL) in 17 subjects in whom the existence...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)45314-8

    authors： Massara F,Genazzani AR,Camanni F,De Leo V,Molinatti GM,Müller EE

    更新日期：1981-02-01 00:00:00

  • Cycle dependency of intrauterine vascular endothelial growth factor levels is correlated with decidualization and corpus luteum function.

    abstract：OBJECTIVE:To determine intrauterine levels of vascular endothelial growth factor (VEGF)-A during the menstrual cycle in the human female and to investigate the impact of decidualization and corpus luteum function. DESIGN:Prospective clinical study. SETTING:Tertiary university center. PATIENT(S):Fifty-four women with...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(03)02165-4

    authors： Licht P,Russu V,Lehmeyer S,Wissentheit T,Siebzehnrübl E,Wildt L

    更新日期：2003-11-01 00:00:00

  • Effects of fibrin sealant on single-layer uterine incision closure in the New Zealand white rabbit.

    abstract：OBJECTIVE:To determine if the addition of fibrin sealant to incision closure in a rabbit uterine horn myomectomy model affects adhesion formation or strength of incision closure. DESIGN:Prospective randomized controlled trial. SETTING:Academic research center. ANIMAL(S):New Zealand white female rabbits. INTERVENTIO...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2005.07.1337

    authors： Peacock KE,Hurst BS,Marshburn PB,Matthews ML

    更新日期：2006-04-01 00:00:00

  • Screening of conditions for rapid freezing of human oocytes: preliminary study toward their cryopreservation.

    abstract：:One hundred and twenty-one freshly-collected human oocytes and 839 unfertilized human oocytes after insemination were cryopreserved by vitrification. The cryoprotectants used were dimethylsulfoxide (DMSO) and sucrose. Vital staining and morphological criteria were used to assess injuries to cells. Variation of the tim...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)61032-4

    authors： Pensis M,Loumaye E,Psalti I

    更新日期：1989-11-01 00:00:00

  • Effect of danazol in vitro and in vivo on monocyte-mediated enhancement of endometrial cell proliferation in women with endometriosis.

    abstract：OBJECTIVE:To investigate danazol's effect in vitro and in vivo on the ability of peripheral blood monocytes (PBM) from women with endometriosis to stimulate endometrial cell proliferation. DESIGN:Uterine endometrial cells from untreated or danazol-treated patients with endometriosis were cultured with or without autol...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：

    authors： Braun DP,Gebel H,Dmowski WP

    更新日期：1994-07-01 00:00:00

  • A mechanism for integrated health care is ideal for women with primary ovarian insufficiency.

    abstract：:It is clear that women with primary ovarian insufficiency are asking the health care community to alter the current standard, which requires the patient to seek a different specialist for each of her health care needs, and instead work as a team of caregivers that embraces each patient as a woman with complex and indi...

    journal_title：Fertility and sterility

    pub_type： 评论,杂志文章

    doi：10.1016/j.fertnstert.2011.03.006

    authors： Sullivan SD

    更新日期：2011-05-01 00:00:00

  • The effect of intrauterine devices containing zinc and copper on their levels in serum.

    abstract：:Serum levels of copper and zinc were determined in 11 health women in whom Latex Leaf intrauterine devices (IUDs) containing copper and zinc had been inserted. Patients with low levels of serum copper or zinc before insertion usually had increased levels of either of these metals while using the device, but they did n...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)43032-3

    authors： Anteby SO,Bassat HA,Yarkoni S,Aboulafia Y,Sadovsky E

    更新日期：1978-01-01 00:00:00

  • A tissue-engineered human endometrial stroma that responds to cues for secretory differentiation, decidualization, and menstruation.

    abstract：OBJECTIVE:To show the responsiveness of tissue-engineered human endometrial stroma to combinations of hormones that mimic the secretory and menstrual phases of the cycle. DESIGN:In vitro experimental study. SETTING:University uterine biology research laboratory. PATIENT(S):None. INTERVENTION(S):Telomerase immortali...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2012.01.098

    authors： Schutte SC,Taylor RN

    更新日期：2012-04-01 00:00:00

  • Effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate on endometrial bleeding.

    abstract：OBJECTIVE:To evaluate vaginal bleeding profiles with lower doses of conjugated equine estrogens (CEE) and medroxyprogesterone acetate (MPA) as continuous combined therapy. DESIGN:The Women's Health, Osteoporosis, Progestin, Estrogen (Women's HOPE) study, a randomized, double-blind, placebo-controlled trial. SETTING:S...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/s0015-0282(01)01792-7

    authors： Archer DF,Dorin M,Lewis V,Schneider DL,Pickar JH

    更新日期：2001-06-01 00:00:00

  • Experimental immunological infertility effect of anti-GAPDH-2 antibodies on the fertility of female mice.

    abstract：OBJECTIVE:To examine the relationship between an antibody against GAPDH-2, a sperm-specific protein, and infertility of female mice. DESIGN:Basic research. SETTING:National Research Institute for Family Planning Beijing, World Health Organization Collaboration Center of Human Reproduction. ANIMAL(S):New Zealand rabb...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2008.09.001

    authors： Wang Y,Zhang N,Zhang X,Miao S,Zong S,Koide SS,Wang L

    更新日期：2009-12-01 00:00:00