Inhibitory avoidance learning inhibits ectonucleotidases activities in hippocampal synaptosomes of adult rats.

abstract：:Somatostatin contents of striatum, hippocampus, and pons medulla have been followed in two inbred strains of mice (C57B1/6J and Balb/cJ) with aging and long term alcohol exposure (over a 25 month period of intoxication). Marked strain dependent differences in basic levels of somatostatin and genotypic variations in re...

journal_title：Neurochemical research

authors： Fuhrmann G,Strosser MT,Besnard F,Kempf E,Kempf J,Ebel A

更新日期：1986-05-01 00:00:00

abstract：:The effects of chronic pentobarbital (PB) treatment on the binding characteristics of [3H]flunitrazepam (FLU) in rat brain were examined. Saline or sodium PB (500 micrograms/10 microliters/hr) was infused into the lateral cerebral ventricles of rats for 6 days using osmotic pumps. Immediately before withdrawal, there ...

journal_title：Neurochemical research

authors： Miyaoka T,Kimura T,Saunders PA,Tseng YT,Ho IK

更新日期：1994-01-01 00:00:00

abstract：:The standard ELISA technique was improved for the detection of antigalactocerebroside antibody in biological fluid. Mouse monoclonal antigalactocerebroside antibody was used to demonstrate specificity and sensitivity of the technique. After optimization of the assay, the usefulness of this measurement for the evaluati...

journal_title：Neurochemical research

authors： Ichioka T,Uobe K,Stoskopf M,Kishimoto Y,Tennekoon G,Tourtellotte WW

更新日期：1988-03-01 00:00:00

abstract：:The endogenous sialidase (N-acetylneuraminidase) activity of membranes prepared from goldfish retina and optic tectum displays characteristics similar to those reported for neural plasma membrane sialidases of other organisms. Endogenous membrane sialidase activity was found to be optimal at ph 4.0, and maximal releas...

journal_title：Neurochemical research

authors： Leskawa KC,Agranoff BW

更新日期：1983-01-01 00:00:00

abstract：:In this review we examine successively: 1) the major effects of thyroid hormone deficiency seen during brain development with special emphasis on the changes in neuronal morphology and migration occurring postnatally in the cerebellum. 2) The effects of this hormone on microtubule assembly during neurite outgrowth and...

journal_title：Neurochemical research

authors： Nunez J,Couchie D,Aniello F,Bridoux AM

更新日期：1991-09-01 00:00:00

abstract：:Previous studies have shown that early life stress induced by maternal separation or non-handling can lead to behavioural deficits in rats and that these deficits can be alleviated by providing palatable cafeteria high-fat diet (HFD). In these studies we investigated the effects of maternal separation or non-handling ...

journal_title：Neurochemical research

authors： Bobrovskaya L,Maniam J,Ong LK,Dunkley PR,Morris MJ

更新日期：2013-04-01 00:00:00

abstract：:Fecal incontinence and constipation still remain the major complications after procedures for anorectal malformations (ARMs). Previous studies have demonstrated a decrease of neural cell in lumbosacral spinal cord of ARMs patients and rat models. However, the underlying mechanism remains elusive. In this study, the ne...

journal_title：Neurochemical research

authors： Yang Z,Geng Y,Yao Z,Jia H,Bai Y,Wang W

更新日期：2017-11-01 00:00:00

abstract：:In the present study, we investigated the effects of pioglitazone (PGZ) in the hippocampal CA1 region of low- or high-fat diet (LFD or HFD) fed gerbils after transient forebrain ischemia. After 8 weeks of LFD or HFD feeding, PGZ (30 mg/kg) was intraperitoneally administered to the gerbils, following which ischemia was...

journal_title：Neurochemical research

authors： Moon SM,Choi GM,Yoo DY,Jung HY,Yim HS,Kim DW,Hwang IK,Cho BM,Chang IB,Cho SM,Won MH

更新日期：2015-05-01 00:00:00

abstract：:The influence of theophylline (2.5--100 mg/kg p.o.) on cyclic 3',5'-adenosine monophosphate (cAMP) and cyclic 3',5'-guanosine monophosphate (cGMP) in brain of Sprague-Dawley rats (0.5--3.0 hr after administration of theophylline) was investigated. It was found that theophylline increases cAMP and cGMP levels when admi...

journal_title：Neurochemical research

authors： Stefanovich V

更新日期：1979-10-01 00:00:00

abstract：:A very large body of evidence from in vivo studies has been accumulated on a link between the change of energy and cell survival/apoptosis. Using an in vitro ischemia model, we have previously shown that ischemia could induce apoptosis in astrocytes. In this study, we utilized the same in vitro model to investigate ch...

journal_title：Neurochemical research

authors： Yu AC,Lau AM,Fu AW,Lau LT,Lam PY,Chen XQ,Xu ZY

更新日期：2002-12-01 00:00:00

abstract：:In the present study, we aimed to investigate the effects of pinealectomy and chronic melatonin administration on focal epileptiform activity induced by penicillin in the rat cortex and to determine the relation between melatonin levels and electrocorticogram (ECoG) power spectrum. For this purpose, male Sprague-Dawle...

journal_title：Neurochemical research

authors： Yildirim M,Aydin-Abidin S,Abidin I,Akca M,Canpolat S,Cansu A

更新日期：2013-08-01 00:00:00

abstract：:N-Methyl-D-aspartate (NMDA) and L-glutamate activate membrane receptors that produce substantial permeation of Na+, K+ and Ca2+ through the neuronal membrane. These ionic fluxes are intimately linked to processes that regulate neuronal survival, growth and differentiation. Intracellular free Ca2+ concentrations are th...

journal_title：Neurochemical research

authors： Michaelis EK,Michaelis ML

更新日期：1992-01-01 00:00:00

abstract：:Remyelination promoting human IgMs effectively increase the number of myelinated axons in animal models of multiple sclerosis. Hence, they ultimately stimulate myelin production by oligodendrocytes (OLs); however, their exact mechanism of action remains to be elucidated, and in particular, it remains unclear whether t...

journal_title：Neurochemical research

authors： Grassi S,Giussani P,Prioni S,Button D,Cao J,Hakimi I,Sarmiere P,Srinivas M,Cabitta L,Sonnino S,Prinetti A

更新日期：2019-06-01 00:00:00

abstract：:The nerve agent VX has a variable and delayed absorption through the skin, which may have implications for treatment regimens. In the present study, central and peripheral effects of percutaneous VX intoxication were investigated in hairless guinea pigs. Although onset times of clinical signs varied considerably, the ...

journal_title：Neurochemical research

authors： Joosen MJ,van der Schans MJ,van Helden HP

更新日期：2008-02-01 00:00:00

abstract：:Cerebral blood flow (CBF) and cerebellar blood flow (CeBF) were measured and correlated with brain lactate, pyruvate and adenosine triphosphate concentrations from groups representing 3-week old suckling (n = 10), 18-22-week old adult (n = 9) and 70-week old aged (n = 7) Sprague-Dawley rats before and during bilateral...

journal_title：Neurochemical research

authors： He Z,Ibayashi S,Sugimori H,Fujii K,Sadoshima S,Fujishima M

更新日期：1997-01-01 00:00:00

abstract：:The serotoninergic system modulates nociceptive and locomotor spinal cord circuits. Exercise improves motor function and changes dopaminergic, noradrenergic, and serotonergic central systems. However, the direct relationship between serotonin, peripheral nerve lesion and aerobic treadmill exercise has not been studied...

journal_title：Neurochemical research

authors： Korb A,Bonetti LV,da Silva SA,Marcuzzo S,Ilha J,Bertagnolli M,Partata WA,Faccioni-Heuser MC

更新日期：2010-03-01 00:00:00

abstract：:The mechanism of focal demyelination in multiple sclerosis has been a long-standing enigma of this disorder. Cytokines, a diverse family of signalling molecules, are viewed as potential mediators of the process based on clinical observations and studies with animal models and tissue/cell culture systems. Myelin and ol...

journal_title：Neurochemical research

authors： Ledeen RW,Chakraborty G

更新日期：1998-03-01 00:00:00

abstract：:Alcohol abuse affects several neurological pathways and causes significant alterations in the brain. Abstention from alcohol causes only a marginal decrease in oxidative stress and neuro inflammation. Our previous studies had shown that an active metabolite of vitamin A, all trans retinoic acid (ATRA), ameliorates alc...

journal_title：Neurochemical research

authors： Priyanka SH,Syam Das S,Thushara AJ,Rauf AA,Indira M

更新日期：2018-09-01 00:00:00

abstract：:Glycogen is the main storage form of glucose in the brain. In contrast with previous beliefs, brain glycogen has recently been shown to play important roles in several brain functions. A fraction of metabolized glucose molecules are being shunted through glycogen before reentering the glycolytic pathway, a phenomenon ...

journal_title：Neurochemical research

authors： Jakobsen E,Bak LK,Walls AB,Reuschlein AK,Schousboe A,Waagepetersen HS

更新日期：2017-09-01 00:00:00

abstract：:The significant increase of free calcium concentration ([Ca2+]i) was found in rat cerebral cortex synaptosomes and hippocampal crude synaptosomal fraction after their exposure to glutamate. But no change of [Ca2+]i was revealed in cerebellar synaptosomes, the slight increase of [Ca2+]i in striatal synaptosomes was not...

journal_title：Neurochemical research

authors： Avrova NF,Shestak KI,Zakharova IO,Sokolova TV,Leont'ev VG

更新日期：1999-09-01 00:00:00

abstract：:This study examined the relationship between the distance of axotomy and the death of injured retinal ganglion cells (RGCs) in adult hamsters and the relationship of cytochrome c and caspase-3 on the death pathway of RGCs. The left optic nerve (ON) of adult hamsters was transected either at 1 or 3 mm away from the opt...

journal_title：Neurochemical research

authors： He MH,Cheung ZH,Yu EH,Tay DK,So KF

更新日期：2004-11-01 00:00:00

abstract：:The secretion of fluid and electrolytes by salivary gland acinar cells requires the coordinated regulation of multiple ion channel and transporter proteins, signaling components, and water transport. Importantly, neurotransmitter stimulated increase in the cytosolic free [Ca(2+)] ([Ca(2+)](i)) is critical for the regu...

journal_title：Neurochemical research

authors： Ambudkar IS

更新日期：2011-07-01 00:00:00

abstract：:The effects of the following drugs: nimodipine (1 mg/kg b.w., i.p.), 2-amino-5-phosphonovaleric acid (4 mg/kg b.w., i.p.) and propentofylline (25 mg/kg b.w., i.p.), administered (alone or in combination) at the end of 15 min bilateral ischemia in gerbils were evaluated on mitochondrial superoxide dismutase (SOD), glut...

journal_title：Neurochemical research

authors： Stanimirovic DB,Micic DV,Markovic M,Spatz M,Mrsulja BB

更新日期：1994-02-01 00:00:00

abstract：:Nicotinic agonists stimulate 22Na flux in rat pheochromocytoma PC12 cells. The stimulatory effect of carbamylcholine is maximal at 1 mM, while the stimulatory effect of nicotine and anatoxin maximize at the same level at 100 microM and 10 microM, respectively. The tertiary amines arecolone and isoarecolone have no eff...

journal_title：Neurochemical research

authors： Daly JW,Nishizawa Y,Edwards MW,Waters JA,Aronstam RS

更新日期：1991-04-01 00:00:00

abstract：:Turmeric has been in use since ancient times as a condiment and due to its medicinal properties. Curcumin, the yellow colouring principle in turmeric, is polyphenolic and major active constituent. Besides anti-inflammatory, thrombolytic and anticarcinogenic activities, curcumin also possesses strong antioxidant proper...

journal_title：Neurochemical research

authors： Shukla PK,Khanna VK,Ali MM,Khan MY,Srimal RC

更新日期：2008-06-01 00:00:00

abstract：:The consumption of flavonoid-rich foods, in particular fruits and vegetables, has been epidemiologically associated with a reduced risk of heart disease, neurodegenerative disease, cancer and other chronic diseases. Flavonoid glycosides, the main class of flavonoids, have been shown to exert CNS-mediated activities, p...

journal_title：Neurochemical research

authors： Fernandez SP,Nguyen M,Yow TT,Chu C,Johnston GA,Hanrahan JR,Chebib M

更新日期：2009-10-01 00:00:00

abstract：:Our previous studies have shown that three sigma (sigma) receptor ligands, (+)-N-allylnormetazocine ((+)-SKF-10,047), (+/-)-pentazocine and 1,3-di(2-tolyl)guanidine (DTG) differently regulated the dopamine (DA) transmission in the rat brain. In the present study, we attempted to clarify the role of sigma 1 receptor su...

journal_title：Neurochemical research

authors： Kobayashi T,Matsuno K,Murai M,Mita S

更新日期：1997-09-01 00:00:00

abstract：:Neuronal differentiation and aging are known to involve many genes, which may also be differentially expressed during these developmental processes. From primary cultured cerebral cortical neurons, we have previously identified various differentially expressed gene transcripts from cultured cortical neurons using the ...

journal_title：Neurochemical research

authors： Yu AC,Sun CX,Li Q,Liu HD,Wang CR,Zhao GP,Jin M,Lau LT,Fung YW,Liu S

更新日期：2005-10-01 00:00:00

abstract：:Silibinin has been widely used to treat liver diseases due to its antioxidant activity. However, the effects of silibinin on the central nervous system have not been thoroughly investigated. The pathological hallmarks of Alzheimer's disease are the accumulation of amyloid β protein, development of neurofibrillary tang...

journal_title：Neurochemical research

authors： Bai D,Jin G,Yin S,Zou D,Zhu Q,Yang Z,Liu X,Ren L,Sun Y,Gan S

更新日期：2017-12-01 00:00:00

abstract：:It has been established that oligodendrocytes, the myelin forming cells, participate in iron homeostasis through the synthesis and secretion of transferrin. Here we investigated whether a correlation exists between myelination, the commonly studied function of oligodendrocytes, and that of transferrin synthesis and se...

journal_title：Neurochemical research

authors： Espinosa de los Monteros A,Kumar S,Zhao P,Huang CJ,Nazarian R,Pan T,Scully S,Chang R,de Vellis J

更新日期：1999-02-01 00:00:00