Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death.

abstract：:Moving the nucleus to a specific position within the cell is an important event during many cell and developmental processes. Several different molecular mechanisms exist to position nuclei in various cell types. In this Commentary, we review the recent progress made in elucidating mechanisms of nuclear migration in a...

journal_title：Journal of cell science

authors： Bone CR,Starr DA

更新日期：2016-05-15 00:00:00

abstract：:The lipid phosphate phosphatase-related proteins (LPPRs), also known as plasticity-related genes (PRGs), are classified as a new brain-enriched subclass of the lipid phosphate phosphatase (LPP) superfamily. They induce membrane protrusions, neurite outgrowth or dendritic spine formation in cell lines and primary neuro...

journal_title：Journal of cell science

authors： Yu P,Agbaegbu C,Malide DA,Wu X,Katagiri Y,Hammer JA,Geller HM

更新日期：2015-09-01 00:00:00

abstract：:The weak spindle integrity checkpoint in Drosophila spermatocytes has revealed a novel function of the gamma-tubulin ring complex (gammaTuRC) in maintaining spindle bipolarity throughout meiosis. Bipolar and bi-astral spindles could form in Drosophila mutants for dd4, the gene encoding the 91 kDa subunit of gammaTuRC....

journal_title：Journal of cell science

authors： Barbosa V,Gatt M,Rebollo E,Gonzalez C,Glover DM

更新日期：2003-03-01 00:00:00

abstract：:Triton X-100-treated sperms were injected into non-nucleate egg fragments of Xenopus laevis to determine whether the structure of the injected sperm nucleus is affected by the cyclic activity of the cytoplasm. Swollen vesicular nuclei were very frequently observed when the sperms were injected and incubated during the...

journal_title：Journal of cell science

authors： Sakai M,Shinagawa A

更新日期：1983-09-01 00:00:00

abstract：:Mob1 is a component of both the mitotic exit network and Hippo pathway, being required for cytokinesis, control of cell proliferation and apoptosis. Cell division accuracy is crucial in maintaining cell ploidy and genomic stability and relies on the correct establishment of the cell division axis, which is under the c...

journal_title：Journal of cell science

authors： Tavares A,Gonçalves J,Florindo C,Tavares AA,Soares H

更新日期：2012-01-15 00:00:00

abstract：:We have shown previously, by fluorescent antibody staining, that desmosomal antigens are widely distributed in the tissues of vertebrate animals. Furthermore, we have demonstrated mutual desmosome formation between cells derived from man, cow, dog, chicken and frog. In this paper we have studied the components of desm...

journal_title：Journal of cell science

authors： Suhrbier A,Garrod D

更新日期：1986-03-01 00:00:00

abstract：:In a wild population of the American newt Notophthalmus viridescens 15 females out of a total of 94 were found to be heterozygous for a paracentric inversion which includes almost the whole of the longer arm of the smallest chromosome (XI). The inversion was recognized in preparations of lampbrush chromosomes because ...

journal_title：Journal of cell science

authors： Hartley SE,Callan HG

更新日期：1977-04-01 00:00:00

abstract：:The glucocorticoid receptor and the mineralocorticoid receptor are hormone-dependent transcription factors. They regulate the excitability of rat hippocampus CA1 neurons in a coordinated fashion. We studied the spatial distribution of these transcription factors in nuclei of CA1 neurons by dual labeling immunocytochem...

journal_title：Journal of cell science

authors： van Steensel B,van Binnendijk EP,Hornsby CD,van der Voort HT,Krozowski ZS,de Kloet ER,van Driel R

更新日期：1996-04-01 00:00:00

abstract：:Mdm2 is a nucleoplasmic and nucleolar protein interacting with p53 and alternative reading frame (ARF) tumor suppressor proteins. Here we demonstrate relocalization and novel interactions of Mdm2 with the promyelocytic leukemia (PML) protein following cellular stress and DNA damage. We show that Mdm2 and PML interact ...

journal_title：Journal of cell science

authors： Kurki S,Latonen L,Laiho M

更新日期：2003-10-01 00:00:00

abstract：:DNA replication in the polytene chromosomes of larval salivary glands of Drosophila hydei has been examined under normal physiological conditions, with or without puromycin, by an autoradiographic procedure using [3H]thymidine. It has been demonstrated that puromycin induces new labelling patterns that can be identifi...

journal_title：Journal of cell science

authors： Mukherjee AS,Chatterjee C

更新日期：1984-01-01 00:00:00

abstract：:Phosphoinositides represent a major class of lipids specifically involved in the organization of signaling cascades, maintenance of the identity of organelles and regulation of multiple intracellular trafficking steps. We previously reported that phosphatidylinositol 5-monophosphate (PI5P), produced by the Shigella fl...

journal_title：Journal of cell science

authors： Boal F,Mansour R,Gayral M,Saland E,Chicanne G,Xuereb JM,Marcellin M,Burlet-Schiltz O,Sansonetti PJ,Payrastre B,Tronchère H

更新日期：2015-02-15 00:00:00

abstract：:Sister-chromatid arm cohesion is lost during the metaphase I/anaphase I transition to allow homologue separation. To obtain needed information on this process we have analysed in grasshopper bivalents the sequential release of arm cohesion in relation to the behaviour of chromatid axes. Results show that sister axes a...

journal_title：Journal of cell science

authors： Suja JA,Antonio C,Debec A,Rufas JS

更新日期：1999-09-01 00:00:00

abstract：:Inactivation of the transcription factor and tumor suppressor p53, and overexpression or mutational activation of PIK3CA, which encodes the p110alpha catalytic subunit of phosphatidylinositol-3-kinase (PI3K), are two of the most common deleterious genomic changes in cancer, including in ovarian carcinomas. We investig...

journal_title：Journal of cell science

authors： Astanehe A,Arenillas D,Wasserman WW,Leung PC,Dunn SE,Davies BR,Mills GB,Auersperg N

更新日期：2008-03-01 00:00:00

abstract：:Muscle regulatory factors activate myogenesis in all vertebrates, but their role has been studied in great detail only in the mouse embryo, where all but myogenin--Myod, Myf5 and Mrf4--are sufficient to activate (albeit not completely) skeletal myogenesis. In the zebrafish embryo, myod and myf5 are required for induct...

journal_title：Journal of cell science

authors： Schnapp E,Pistocchi AS,Karampetsou E,Foglia E,Lamia CL,Cotelli F,Cossu G

更新日期：2009-02-15 00:00:00

abstract：:The LEM domain (for lamina-associated polypeptide, emerin, MAN1 domain) defines a group of nuclear proteins that bind chromatin through interaction of the LEM motif with the conserved DNA crosslinking protein, barrier-to-autointegration factor (BAF). Here, we describe a LEM protein annotated in databases as 'Ankyrin r...

journal_title：Journal of cell science

authors： Brachner A,Braun J,Ghodgaonkar M,Castor D,Zlopasa L,Ehrlich V,Jiricny J,Gotzmann J,Knasmüller S,Foisner R

更新日期：2012-02-15 00:00:00

abstract：:Programmed cell death comprises several subtypes, as revealed by electron microscopy. Apoptosis or type I programmed cell death is characterized by condensation of cytoplasm and preservation of organelles, essentially without autophagic degradation. Autophagic cell death or type II programmed cell death exhibits exten...

journal_title：Journal of cell science

authors： Bursch W,Hochegger K,Torok L,Marian B,Ellinger A,Hermann RS

更新日期：2000-04-01 00:00:00

abstract：:Compartmentalization of membrane transport and signaling processes is of pivotal importance to eukaryotic cell function. While plasma membrane compartmentalization and dynamics are well known to depend on the scaffolding function of septin GTPases, the roles of septins at intracellular membranes have remained largely ...

journal_title：Journal of cell science

authors： Song K,Gras C,Capin G,Gimber N,Lehmann M,Mohd S,Puchkov D,Rödiger M,Wilhelmi I,Daumke O,Schmoranzer J,Schürmann A,Krauss M

更新日期：2019-02-01 00:00:00

abstract：:The surface of the ciliate Dileptus contains locomotor and sensory domains. Each domain contains cilia of its own kind, arranged in a characteristic pattern. Transformation of a portion of the locomotor area into the sensory domain has been studied. Locomotor ciliary units in the transforming area undergo resorption o...

journal_title：Journal of cell science

authors： Golinska K

更新日期：1983-07-01 00:00:00

abstract：:Cornichon proteins are structurally related transmembrane proteins that have been studied in and Drosophila and yeast. In Drosophila, Cornichon (Cni) is involved in embryo polarization by the TGFalpha-related Gurken. In yeast, the Cni-related Erv14 is required for axial budding. A cargo receptor function has been prop...

journal_title：Journal of cell science

authors： Castro CP,Piscopo D,Nakagawa T,Derynck R

更新日期：2007-07-15 00:00:00

abstract：:How signaling domains form is an important, yet largely unexplored question. Here, we show that ciliary proteins help establish two contiguous, yet distinct cyclic GMP (cGMP) signaling compartments in Caenorhabditis elegans thermosensory AFD neurons. One compartment, a bona fide cilium, is delineated by proteins assoc...

journal_title：Journal of cell science

authors： Nguyen PA,Liou W,Hall DH,Leroux MR

更新日期：2014-12-15 00:00:00

abstract：:Tissues fixed in osmium tetroxide or in combined osmium and glutaraldehyde (Hinde), embedded in Spurr's medium, cut at 0-5-I mum and mounted in Farrants' gum medium containing ethyl gallate, show good staining of lipid-contaning structures (droplets of triglyceride, membranes, mitochondria, etc.) in the light microsco...

journal_title：Journal of cell science

authors： Wigglesworth VB

更新日期：1975-12-01 00:00:00

abstract：:We have cloned and characterized a single copy C. reinhardtii gene containing an open reading frame of 333 nucleotides encoding a 12.7 kDa protein. The novel protein, DIP13, exhibits 60% identity with two mammalian proteins, human NA14 and an unnamed mouse protein. Homologous sequences are also present in several prot...

journal_title：Journal of cell science

authors： Pfannenschmid F,Wimmer VC,Rios RM,Geimer S,Kröckel U,Leiherer A,Haller K,Nemcová Y,Mages W

更新日期：2003-04-15 00:00:00

abstract：:Clusterin expression is increased in tissues undergoing apoptosis, including neurodegenerative retina, but the causal relationships remain to be clarified. To test the hypothesis that overexpression of clusterin could induce apoptosis in neurons, transgenic mice were generated in which rat clusterin transgene was expr...

journal_title：Journal of cell science

authors： Jomary C,Chatelain G,Michel D,Weston A,Neal MJ,Jones SE

更新日期：1999-05-01 00:00:00

abstract：:The extracellular environment and tissue architecture contribute to proper cell function and growth control. Cells growing in monolayers on standard polystyrene tissue culture plates differ in their shape, growth rate and response to external stimuli, compared with cells growing in vivo. Here, we showed that the EGFR ...

journal_title：Journal of cell science

authors： Mizushima H,Wang X,Miyamoto S,Mekada E

更新日期：2009-12-01 00:00:00

abstract：:The E-cadherin-catenin complex regulates Ca(2+)-dependent cell-cell adhesion and is localized to the basolateral membrane of polarized epithelial cells. Uncoupling beta-catenin from E-cadherin by deletion or substitution mutations causes accumulation of these proteins in intracellular compartments, including the trans...

journal_title：Journal of cell science

authors： Miyashita Y,Ozawa M

更新日期：2007-12-15 00:00:00

abstract：:Cultured endothelial cells isolated from fenestrated capillaries express many properties characteristic of their in vivo differentiated phenotype, including the formation of a limited number of fenestrae. In this study, we have investigated whether physiological factors that control cell differentiation might regulate...

journal_title：Journal of cell science

authors： Lombardi T,Montesano R,Furie MB,Silverstein SC,Orci L

更新日期：1988-10-01 00:00:00

abstract：:Human erythrocytes suspended in buffered isotonic saline were frozen to the temperature of liquid nitrogen at various cooling rates of 3, 140, 700, 1800, 3500, 8000 and 11 500 deg. C/min. The membrane ultrastructure in the frozen state and the extent of haemolysis after thawing were examined at each cooling rate. As t...

journal_title：Journal of cell science

authors： Fujikawa S

更新日期：1981-06-01 00:00:00

abstract：:Accurate chromosome segregation requires the spindle assembly checkpoint to be active at the onset of mitosis, before being silenced following chromosome alignment. p31(comet) is a checkpoint antagonist in that its inhibition delays mitotic exit, whereas its overexpression overrides the checkpoint. How exactly p31(com...

journal_title：Journal of cell science

authors： Westhorpe FG,Tighe A,Lara-Gonzalez P,Taylor SS

更新日期：2011-11-15 00:00:00

abstract：:Adult newt cardiomyocytes, in contrast to their mammalian counterparts, can proliferate after injury and contribute to the functional regeneration of the heart. In order to understand the mechanisms underlying this plasticity we performed longitudinal studies on single cardiomyocytes in culture. We find that the major...

journal_title：Journal of cell science

authors： Bettencourt-Dias M,Mittnacht S,Brockes JP

更新日期：2003-10-01 00:00:00

abstract：:The CHO1 antigen is a mitosis-specific kinesin-like motor located at the interzonal region of the spindle. The human cDNA coding for the antigen contains a domain with sequence similarity to the motor domain of kinesin-like protein (Nislow et al., Nature 359, 543, 1992). Here we cloned cDNAs encoding the CHO1 antigen ...

journal_title：Journal of cell science

authors： Kuriyama R,Dragas-Granoic S,Maekawa T,Vassilev A,Khodjakov A,Kobayashi H

更新日期：1994-12-01 00:00:00