Volatile fatty acid, metabolic by-product of periodontopathic bacteria, induces apoptosis in WEHI 231 and RAJI B lymphoma cells and splenic B cells.

abstract：:The action of injected bacterial lipopolysaccharide upon the uptake of cytophilic antibodies by macrophages was found to be unrelated either to changes in surface charge or to the rate of anaerobic glycolysis of these cells. It is apparently mediated by alterations in the levels of material in the serum which enhances...

journal_title：Infection and immunity

authors： Tizard IR

更新日期：1971-10-01 00:00:00

abstract：:Nonspecific interactions related to physicochemical properties of bacterial cell surfaces, such as hydrophobicity and electrostatic charge, are known to have important roles in bacterium-host cell encounters. Streptococcus pneumoniae (pneumococcus) expresses multiple, surface-exposed, choline-binding proteins (CBPs) w...

journal_title：Infection and immunity

authors： Swiatlo E,Champlin FR,Holman SC,Wilson WW,Watt JM

更新日期：2002-01-01 00:00:00

abstract：:Babesiosis has long been recognized as an economically important disease of cattle, but only in the last 30 years has Babesia been recognized as an important pathogen in humans. Invasion of erythrocytes is an integral part of the Babesia life cycle. However, very little information is available on the molecules involv...

journal_title：Infection and immunity

authors： Lobo CA

更新日期：2005-01-01 00:00:00

abstract：:Human sera were examined by an enzyme-linked immunosorbent assay for immunoglobulin G (IgG) and IgM antibodies to purified type III polysaccharide of group B streptococci. The antigen-binding capacity of a reference human serum was determined by a radioimmunoassay, and the total antibody content was determined by quan...

journal_title：Infection and immunity

authors： Anthony BF,Concepcion NF,Wass CA,Heiner DC

更新日期：1984-10-01 00:00:00

abstract：:Bordetella pertussis adenylate cyclase-hemolysin (AC-Hly), encoded by the cyaA gene, belongs to the RTX family of toxins with extensive glycine-rich repeats in the carboxy-terminal portion. AC-Hly possesses both adenylate cyclase toxic and hemolytic activities that depend on a posttranslational modification mediated b...

journal_title：Infection and immunity

authors： Betsou F,Sebo P,Guiso N

更新日期：1993-09-01 00:00:00

abstract：:Relapsing fever (RF) is a spirochetal infection characterized by periods of sickness with fever at time of high bacteremia that alternate with afebrile periods of relative well being during low bacteremia. Patients with epidemic RF who are doing relatively well have extraordinarily high levels of interleukin-10 (IL-10...

journal_title：Infection and immunity

authors： Londoño D,Marques A,Hornung RL,Cadavid D

更新日期：2008-12-01 00:00:00

abstract：:Streptolysin O (SLO) and streptolysin S (SLS) are potent cytolytic toxins produced by almost all clinical isolates of group A streptococci (GAS). Allele-replacement mutagenesis was used to construct nonpolar (in-frame) deletion mutations in the slo and sagB genes of the serotype M5 GAS strain Manfredo, producing isoge...

journal_title：Infection and immunity

authors： Fontaine MC,Lee JJ,Kehoe MA

更新日期：2003-07-01 00:00:00

abstract：:The pH 6 antigen (Psa) of Yersinia pestis consists of fimbriae with adhesive properties of potential importance for the pathogenesis of plague, including pneumonic plague. The Psa fimbriae mediate bacterial binding to human alveolar epithelial cells. The Psa fimbriae bound mostly to one component present in the total ...

journal_title：Infection and immunity

authors： Galván EM,Chen H,Schifferli DM

更新日期：2007-03-01 00:00:00

abstract：:Antibody levels in sera and respiratory secretions and resistance to respiratory infections were examined in mice given live infuenza virus in small-particle (2 mum) aerosols, large-particle (10 mum) aerosols, intraperitoneally, and subcutaneously. After parenteral administration antibody was found primarily in the se...

journal_title：Infection and immunity

authors： Scott GH,Sydiskis RJ

更新日期：1976-03-01 00:00:00

abstract：:To evaluate the enteropathogenicity of Aeromonas hydrophila and Plesiomonas shigelloides, the rate of isolation of these organisms was compared among individuals with and without diarrhea in Thailand. In two groups of American travelers, A. hydrophila, but not P. shigelloides, was associated with episodes of travelers...

journal_title：Infection and immunity

authors： Pitarangsi C,Echeverria P,Whitmire R,Tirapat C,Formal S,Dammin GJ,Tingtalapong M

更新日期：1982-02-01 00:00:00

abstract：:The enzymes responsible for reducing H2O2 were surveyed in 49 strains of Leptospira by using semiquantitative assays for catalase and peroxidase. The survey revealed a differential distribution of catalase and peroxidase activities between the two leptospiral complexes. The pathogenic Leptospira interrogans strains ga...

journal_title：Infection and immunity

authors： Corin RE,Boggs E,Cox CD

更新日期：1978-12-01 00:00:00

abstract：:Blastomyces dermatitidis is a thermally induced dimorphic fungus capable of causing lung and systemic infections in immunocompetent animal hosts. With the publication of genomic sequences from three different strains of B. dermatitidis and the development of RNA interference as a gene-silencing tool, it has become pos...

journal_title：Infection and immunity

authors： Krajaejun T,Wüthrich M,Gauthier GM,Warner TF,Sullivan TD,Klein BS

更新日期：2010-06-01 00:00:00

abstract：:Using a murine respiratory infection model, we have demonstrated previously that infection with Bordetella pertussis or immunization with a whole-cell pertussis vaccine induced antigen-specific Th1 cells, which conferred a high level of protection against aerosol challenge. In contrast, immunization with an acellular ...

journal_title：Infection and immunity

authors： Mahon BP,Ryan MS,Griffin F,Mills KH

更新日期：1996-12-01 00:00:00

abstract：:A 75-kilodalton major protein (75K protein) was purified to homogeneity from the cell lysate fraction and the envelope of Bacteroides gingivalis 381. The 75K protein was originally present in the outer membrane or the outermost part of this organism as a large, stable complex with an apparent molecular weight of about...

journal_title：Infection and immunity

authors： Yoshimura F,Watanabe K,Takasawa T,Kawanami M,Kato H

更新日期：1989-11-01 00:00:00

abstract：:We previously showed that cytotoxic necrotizing factor 1 (CNF1) contributes to Escherichia coli K1 invasion of human brain microvascular endothelial cells (HBMEC) and interacts with the receptor on the surface of HBMEC. CNF1 is the cytoplasmic protein, and it remains incompletely understood how CNF1 is secreted across...

journal_title：Infection and immunity

authors： Yu H,Kim KS

更新日期：2010-02-01 00:00:00

abstract：:Mannan (MAN) extracted from Candida albicans 20A was investigated for its potential as an antigen in the detection of cell-mediated immunity (CMI) in vivo and in vitro and for its ability to modulate CMI when administered intravenously (i.v.). CBA/J mice were either immunized as adults by the cutaneous inoculation of ...

journal_title：Infection and immunity

authors： Domer JE,Garner RE,Befidi-Mengue RN

更新日期：1989-03-01 00:00:00

abstract：:Genetic diversity and relationships among 109 isolates of Neisseria meningitidis obtained from throat cultures of healthy individuals in Norway in 1984 were assessed by analyzing electrophoretically demonstrable allelic variation at 15 enzyme-encoding chromosomal genes. Seventy-eight distinctive electrophoretic types ...

journal_title：Infection and immunity

authors： Caugant DA,Kristiansen BE,Frøholm LO,Bøvre K,Selander RK

更新日期：1988-08-01 00:00:00

abstract：:To investigate the correlation between the incA I47T mutation in Chlamydia trachomatis and the nonfusogenic phenotype, the incA genes of 25 isolates were sequenced. Four major sequence types were identified. Seven isolates (28%) had the I47T mutation. Isolates representing the four sequence types expressed IncA in the...

journal_title：Infection and immunity

authors： Pannekoek Y,van der Ende A,Eijk PP,van Marle J,de Witte MA,Ossewaarde JM,van den Brule AJ,Morré SA,Dankert J

更新日期：2001-07-01 00:00:00

abstract：:The plasma level of the chemokine CCL3 is elevated in patients with chronic severe schistosomiasis mansoni. We have previously shown that CCL3(-/-) mice with experimental infection showed diminished pathology and worm burden compared to those of wild-type (WT) mice. To elucidate further the role of CC chemokines durin...

journal_title：Infection and immunity

authors： Souza AL,Souza PR,Pereira CA,Fernandes A,Guabiraba R,Russo RC,Vieira LQ,Corrêa A Jr,Teixeira MM,Negrão-Corrêa D

更新日期：2011-04-01 00:00:00

abstract：:Streptococcus pneumoniae remains a major causative agent of serious human diseases. The worldwide increase of antibiotic resistant strains revealed the importance of horizontal gene transfer in this pathogen, a scenario that results in the modulation of the species-specific gene pool. We investigated genomic variation...

journal_title：Infection and immunity

authors： Hakenbeck R,Balmelle N,Weber B,Gardès C,Keck W,de Saizieu A

更新日期：2001-04-01 00:00:00

abstract：:Rabbits were immunized with the synthetic peptide EENVEHDA or (EENV)2, corresponding to a tandemly repeated sequence in the C-terminal part of the Plasmodium falciparum antigen Pf155/RESA, or with Escherichia coli-derived fusion proteins containing the corresponding repeats. For all sera, the capacity of the total imm...

journal_title：Infection and immunity

authors： Wåhlin B,Berzins K,Perlmann H,Anders RF,Perlmann P

更新日期：1990-09-01 00:00:00

abstract：:Using polystyrene microspheres coated with heparin or heparan sulfate, it was shown that coated microspheres specifically bound eukaryotic cells and were endocytosed by nonprofessional phagocytic cells. Coated microspheres displayed properties of binding to eukaryotic cells that were similar to those of chlamydiae, an...

journal_title：Infection and immunity

authors： Stephens RS,Fawaz FS,Kennedy KA,Koshiyama K,Nichols B,van Ooij C,Engel JN

更新日期：2000-03-01 00:00:00

abstract：:The nucleotide sequences of three previously undescribed Pseudomonas aeruginosa pilin structural genes are presented. Comparisons of deduced pilin primary structure and flanking DNA sequence allowed placement of these and six previously published sequences into one of two groups. Epitope mapping, using overlapping imm...

journal_title：Infection and immunity

authors： Castric PA,Deal CD

更新日期：1994-02-01 00:00:00

abstract：:Conjugated polysaccharide vaccines protect against serogroup C meningococci. However, this approach cannot be applied to serogroup B, which is still a major cause of meningitis. We evaluated the immunogenicity of three surface-exposed proteins from serogroup B Neisseria meningitidis (App, NhhA, and NadA) identified du...

journal_title：Infection and immunity

authors： Bowe F,Lavelle EC,McNeela EA,Hale C,Clare S,Arico B,Giuliani MM,Rae A,Huett A,Rappuoli R,Dougan G,Mills KH

更新日期：2004-07-01 00:00:00

abstract：:Recent work has demonstrated that the polyketide natural product Aurodox from Streptomyces goldiniensis is able to block the pathogenesis of the murine pathogen Citrobacter rodentium In this work, we aimed to gain a better understanding of the mechanism of action of the compound. We show that Aurodox downregulates the...

journal_title：Infection and immunity

authors： McHugh RE,O'Boyle N,Connolly JPR,Hoskisson PA,Roe AJ

更新日期：2019-01-24 00:00:00

abstract：:Patients with chronic bronchitis are colonized by and may develop acute bronchopulmonary infection due to nontypable Haemophilus influenzae (NTHI) despite the presence of bactericidal and opsonizing antibody to the infecting organism. To test the hypothesis that secretory immunoglobulin A (IgA) interferes with host de...

journal_title：Infection and immunity

authors： Musher DM,Goree A,Baughn RE,Birdsall HH

更新日期：1984-07-01 00:00:00

abstract：:Bacterial overgrowth in the small bowel is known to occur in patients with persistent diarrhea, but it has been unclear if colonization alone causes fluid secretion. We studied isogenic, nontoxigenic Escherichia coli strains with colonizing factor antigen II (CFA/II) (1392+) and without CFA/II (1392-) in 18-h rabbit i...

journal_title：Infection and immunity

authors： Wanke CA,Guerrant RL

更新日期：1987-08-01 00:00:00

abstract：:Salmonella enterica serovar Enteritidis is a major cause of food-borne diseases associated with consumption of shell eggs. Clinical isolates of S. enterica serovar Enteritidis exhibit a wide spectrum of virulence in mice. A highly virulent isolate (SE2472) was previously shown to be more resistant in vitro than other ...

journal_title：Infection and immunity

authors： Lu S,Killoran PB,Fang FC,Riley LW

更新日期：2002-02-01 00:00:00

abstract：:Vaccination with native full-length merozoite surface protein 1 (MSP1) or with recombinant C-terminal peptides protects mice against lethal challenge with virulent malaria parasites. To determine whether other regions of MSP1 can also induce protection, Plasmodium yoelii MSP1 was divided into four separate regions. Ea...

journal_title：Infection and immunity

authors： Tian JH,Kumar S,Kaslow DC,Miller LH

更新日期：1997-08-01 00:00:00

abstract：:Indoleamine 2,3-dioxygenase (IDO), a tryptophan-degrading enzyme, is inducible by various interferons (IFNs). IDO-mediated tryptophan degradation, but not the formation of IDO-catalyzed tryptophan metabolites, has been suggested as a mechanism for the antiparasitic action of IFN-gamma. To determine whether the IFN-gam...

journal_title：Infection and immunity

authors： Habara-Ohkubo A,Shirahata T,Takikawa O,Yoshida R

更新日期：1993-05-01 00:00:00