Abstract:
UNLABELLED:The purpose of this study was to determine the effect of low birth weight at term on serum lipoproteins. Lipid and apolipoprotein (apo) contents were investigated in cord sera of small-for-gestational-age (SGA) newborns at term (2290 g +/- 33 g) and compared with those of appropriate-for-gestational-age (AGA) newborns (3570 g +/- 93 g). In SGA newborns, VLDL amounts were twofold higher, whereas LDL, HDL2 and HDL3 contents were lower than in AGA newborns (-38%, -44% and -42%, respectively). VLDL-triacylglycerols (TG), apo B-100 and apo E were higher, while VLDL-apo C-II values were 39% lower in SGA newborns compared with those of AGA newborns. In SGA newborns, HDL2-apolipoprotein, phospholipid and cholesteryl ester levels were respectively reduced to 70%, 50% and 40% compared with AGA values. HDL3-apolipoprotein and phospholipid contents were also decreased in SGA newborns (-43% and -60%, respectively). The different HDL2 and HDL3-apolipoproteins (apo A-I, A-II, C-III and E) were significantly decreased in SGA newborns. CONCLUSION:Intra-uterine growth retardation was accompanied by alterations in apolipoproteins and lipid compositions in the four lipoprotein fractions, which may impair lipid metabolism. Follow up studies on lipoprotein patterns in SGA infants are required to investigate whether such abnormalities at birth lead to diseases in adulthood.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Merzouk H,Meghelli-Bouchenak M,el-Korso N,Belleville J,Prost Jdoi
10.1007/s004310050820subject
Has Abstractpub_date
1998-04-01 00:00:00pages
321-6issue
4eissn
0340-6199issn
1432-1076journal_volume
157pub_type
杂志文章abstract:UNLABELLED:The inherited ion channel disorders (channelopathies) are a group of disorders caused by mutations in genes encoding ion channels. Ion channel disorders can affect any tissue, but the majority affect skeletal muscle or the central nervous system. These disorders include skeletal muscle sodium channelopathies...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/pl00014403
更新日期:2000-12-01 00:00:00
abstract::The new coronavirus disease outbreak in 2019 (COVID-19) represents a dramatic challenge for healthcare systems worldwide. As to viral tropism, lungs are not the only COVID-19 target but also the heart may be involved in a not negligible percentage of the infected patients. Myocarditis-related cardiac dysfunction and p...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-020-03699-0
更新日期:2020-07-01 00:00:00
abstract:UNLABELLED:A 15-year-old healthy girl ingested 38.25 g (0.55 g/kg body weight) of metformin in a suicide attempt. Subsequently she developed lactic acidosis and moderate renal failure. An initial session of haemodialysis was able to treat the acidosis and reduce the toxic level of metformin. Nevertheless, a further inc...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-005-1634-y
更新日期:2005-06-01 00:00:00
abstract::Inappropriate use of antibiotics in human and animal is one of the causes of antimicrobial resistance. This study evaluates the prevalence and predictors of antibiotic use among pediatric patients visiting the Emergency Department (ED) in Malaysia. A retrospective cross-sectional study was conducted in the ED of a ter...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-019-03560-z
更新日期:2020-05-01 00:00:00
abstract:INTRODUCTION:Newborns with intrauterine growth retardation (IUGR) have multiple risk factors for developing hypoglycaemia. Hyperinsulinism, both transient and prolonged, is one of the major risk factors responsible for the hypoglycaemia observed in some newborns with IUGR. Once the child has progressed beyond the infan...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-006-0371-1
更新日期:2007-10-01 00:00:00
abstract::The objective of this study was to determine the outcomes of Croatian children with biliary atresia. Health records of infants born in Croatia between January 1, 1992 and December 31, 2006 who were diagnosed with biliary atresia and treated at a single university center were reviewed. Survival rates were calculated wi...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-010-1266-8
更新日期:2010-12-01 00:00:00
abstract::Despite multiple recommendations, intramuscular epinephrine is poorly prescribed in emergency department receiving pediatric anaphylaxis. To evaluate the role of severity symptoms on this use, we included all admissions for a diagnosis linked to possible allergy in the two pediatric emergency departments of our instit...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-018-3246-3
更新日期:2019-01-01 00:00:00
abstract::There has been some limited progress in the understanding of the basic defect in Wilson disease and the gene concerned has been located to the chromosome region 13q14. Treatment with zinc has emerged as a definite alternative to penicillamine administration and some shortcomings and/or hazards of both forms of therapy...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF01963553
更新日期:1991-01-01 00:00:00
abstract::Clinically visible corneal opacities were observed in a patient with an extremely severe form of mucopolysaccharidosis II. In a second patient with an unusually mild form of mucopolysaccharidosis II, discrete corneal opacities were detected by slit-lamp examination. Thus clear corneae can no longer be regarded as a ha...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441369
更新日期:1978-08-17 00:00:00
abstract::An 8-year-old boy with an hepatic form of Wilson disease was treated with oral zinc sulphate as the primary and sole therapy. After 4 months, liver function had dramatically improved, and the parameters characterizing copper metabolism had also normalized. ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441526
更新日期:1989-06-01 00:00:00
abstract::Serum bile acids and their conjugates were analysed in 20 breast-fed infants with prolonged jaundice. The mean total bile acid levels in serum were increased in the breast-fed infants with jaundice, as compared with those in either breast- or bottle-fed infants without jaundice. However, there were no significant diff...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00491922
更新日期:1985-05-01 00:00:00
abstract:UNLABELLED:Lymphocytic hypophysitis is a rare disorder predominantly affecting females during the antepartum or postpartum period. It is characterized by destruction and lymphocytic infiltration of the pituitary gland, probably by an autoimmune process, leading to a pituitary mass lesion and/or various degrees of hypop...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s004310050690
更新日期:1997-09-01 00:00:00
abstract:UNLABELLED:Reports on schistosomiasis in children growing up in Europe are rare despite increased travel activity. We report on eight male and three female German children aged 50 months to 15 years with schistosomiasis. Six children were asymptomatic, whereas two presented with typical signs of Katayama fever. Persist...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s004310051326
更新日期:2000-07-01 00:00:00
abstract::We hypothesized that because 45,X/46,XY (X/XY) children share a cell line with Turner syndrome (TS), they also share co-morbidities described in TS. In addition, the presence of the Y chromosome in brain and in other body tissues would influence their function. On the basis of our findings, we aimed to establish optim...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-011-1600-9
更新日期:2012-03-01 00:00:00
abstract::Acute urinary tract infection (UTI) is the most common bacterial infection in childhood. Although hyponatremia was described in ~ 2/3 of these children, its clinical significance is still unclear. Herein, we evaluated the prevalence and clinical implications of hyponatremia in children hospitalized with a UTI. Medical...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-020-03808-z
更新日期:2020-09-19 00:00:00
abstract:UNLABELLED:Storage of human breast milk by freezing or refrigeration of milk with and without heating have been recommended. This can hardly be avoided because of the social circumstances of most mothers who are regularly separated from their infants because of work or schooling as well as the particular needs of some ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s004310000577
更新日期:2000-11-01 00:00:00
abstract:UNLABELLED:The purpose of this study was to assess how much of the variance in intellectual outcome at 2 and 6 years of age could be attributed to treatment variables in children with congenital hypothyroidism, and which of the parameters used for monitoring treatment predicted later development. Forty-five children, e...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF01955261
更新日期:1996-05-01 00:00:00
abstract::Despite rapidly evolving knowledge about COVID 19 infection, routes of perinatal COVID 19 transmission and viral load in mother neonate dyad remain uncertain. Data were analysed to describe the clinicodemographic profile and viral load in neonates born to COVID 19 positive mothers. Of 2947 deliveries, 69 mothers were ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-020-03800-7
更新日期:2021-02-01 00:00:00
abstract::Continuous negative extrathoracic pressure (CNEP) has been recently reintroduced as therapy for respiratory failure. To determine its effects on cardiac output a pilot study was performed in ten patients aged 2 months-3 years (median 4 months). All had chronic respiratory failure (seven with bronchopulmonary dysplasia...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF01954088
更新日期:1993-07-01 00:00:00
abstract::Diagnostic tools for the management of acute osteomyelitis (OM) and septic arthritis (SA) have improved over the last decade. To investigate the influence and availability of magnetic resonance imaging (MRI) and nucleic acid testing (NAT), a retrospective cohort study was done. Patients admitted with acute OM or SA be...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-018-3157-3
更新日期:2018-07-01 00:00:00
abstract:UNLABELLED:Improved surgical care during the last decades, together with advances in medical management, led to a remarkable increase in survival of patients with congenital heart disease (CHD). However, aging of the CHD population brings new challenges, and loss of follow-up of adolescents and adults with CHD is a maj...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s00431-015-2557-x
更新日期:2015-07-01 00:00:00
abstract:UNLABELLED:Administration of human growth hormone (GH) has yielded conflicting results concerning its role on thyroid function in patients with Ullrich-Turner syndrome. Therefore, we investigated the course of thyroid hormone parameters and thyroxin binding globulin in relation to GH therapy, IGF-I and additional oxand...
journal_title:European journal of pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s004310050563
更新日期:1997-02-01 00:00:00
abstract::Serum IgE concentration was measured on the 5th day of life in 943 infants. All infants were included in a 3 month follow-up study. The frequency of cow's milk allergy was studied according to either family history, IgE level, or both. Feeding (mother's milk or formula feeding) was taken into account. Manifestations s...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02429049
更新日期:1986-12-01 00:00:00
abstract::In a German pediatric oncology unit, the attending physicians diagnosed 27 cases of Clostridium difficile-associated disease (CDI) from January 01, 2010 to October 31, 2013. This refers to a CDI incidence density of 2.0/1000 inpatient days. According to the hospital hygiene standard, symptomatic patients with CDI were...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-017-3070-1
更新日期:2018-03-01 00:00:00
abstract::We aimed to demonstrate the value of monitoring infants with arteriovenous malformation (AVM) during endovascular embolization with integrated evaluation of hemodynamics (IEH) and guiding decisions according to the underlying pathophysiology. This is a retrospective analysis of the perioperative hemodynamics data for ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-020-03735-z
更新日期:2021-01-01 00:00:00
abstract::When a mother with tetralogy of Fallot has a conotruncal anomaly face, her child might have a 22q11.2 deletion and severe congenital heart disease. ...
journal_title:European journal of pediatrics
pub_type: 信件
doi:10.1007/s00431-001-0890-8
更新日期:2002-03-01 00:00:00
abstract:UNLABELLED:Increased breastfeeding was suggested as a contributing factor to significant hyperbilirubinemia. The aim of this study was to identify the risk factors associated with jaundice in exclusively breastfed term neonates. We retrospectively reviewed all consecutively live-born neonates from August 2009 to July 2...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-011-1512-8
更新日期:2012-01-01 00:00:00
abstract::In this study messenger ribonucleic acid (mRNA) and DNA of five Wilms tumours were investigated. As expected, the level of insulin-like growth factor (IGF) II-mRNA was elevated up to 50 times in tumour tissue as compared to normal adjacent kidney tissue. In addition, genomic DNA was isolated and digested with appropri...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF00441514
更新日期:1989-06-01 00:00:00
abstract::To clarify the relationship between hyperbilirubinaemia and abnormal results of biochemical liver function tests in infants with breast milk jaundice (BMJ), 58 breast-fed infants with indirect hyperbilirubinaemia were enrolled in this study. Sera obtained from the above infants were subjected to routine liver function...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF01955928
更新日期:1991-03-01 00:00:00
abstract::We report on a youngster followed by his paediatrician from birth until 14 years of age for premature beats, most likely of ventricular origin. The sudden death of his sister provoked a re-assessment of his electrocardiograms (ECG), resulting in the diagnosis of Brugada syndrome and the subsequent implantation of a ca...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s00431-006-0150-z
更新日期:2006-08-01 00:00:00