Abstract:
UNLABELLED:A 15-year-old healthy girl ingested 38.25 g (0.55 g/kg body weight) of metformin in a suicide attempt. Subsequently she developed lactic acidosis and moderate renal failure. An initial session of haemodialysis was able to treat the acidosis and reduce the toxic level of metformin. Nevertheless, a further increase in serum lactate was observed during and after the first dialysis treatment. A second session of haemodialysis was started 5 h after the end of the first session and resulted in a lowering of the lactate level and an almost total elimination of metformin. During the further clinical course, reversible acute renal failure with a maximum creatinine of 2.4 mg/dl was observed. CONCLUSION:Despite sufficient haemodialysis, the production of lactate can be greater than the elimination in the case of severe metformin intoxication. Therefore haemodialysis should be continued even in the situation of rising lactate levels during the treatment.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Lacher M,Hermanns-Clausen M,Haeffner K,Brandis M,Pohl Mdoi
10.1007/s00431-005-1634-ykeywords:
subject
Has Abstractpub_date
2005-06-01 00:00:00pages
362-5issue
6eissn
0340-6199issn
1432-1076journal_volume
164pub_type
杂志文章abstract::No previous studies have focused on postoperative fat malabsorption in children with choledochal cyst (CC) who undergo cyst excision and Roux-en-Y (RY) hepatico-jejunostomy (HJ), a combination of procedures that can lead to the non-physiological mixture of food and bile juice. To examine the effect of RYHJ with cholec...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-008-0703-4
更新日期:2009-01-01 00:00:00
abstract:UNLABELLED:The aim of the study was to determine the characteristic features and outcome of carcinoid or mucoepidermoid tumours in children. A retrospective analysis of all patients treated for a carcinoid or mucoepidermoid tumour in France between 1984 and 2001 was performed. There were 11 cases of carcinoid tumour an...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-005-1740-x
更新日期:2005-12-01 00:00:00
abstract::Tinea of the nails is not an exclusively adult pathology. The pediatrician should include this entity in the differential diagnosis. ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-006-0332-8
更新日期:2007-09-01 00:00:00
abstract:UNLABELLED:Adipsic hypernatraemia is an uncommon disorder in childhood caused by a defect in the osmoregulation of thirst, leading to impairment of water homeostasis and chronic hyperosmolality of body fluids. Adipsia is often associated with an abnormality in osmoregulated vasopressin secretion due to the close proxim...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-004-1495-9
更新日期:2004-10-01 00:00:00
abstract::We report what we believe to be the first case of simultaneous infection by Toxoplasma gondii and cytomegalovirus in a newborn. ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00496426
更新日期:1988-05-01 00:00:00
abstract::Maternal morbidity is associated with cesarean deliveries. However, new evidence suggests that short- and long-term neonatal morbidity is also associated. This includes respiratory morbidity with conflicting results. To determine whether mode of delivery has an impact on the long-term risk for respiratory morbidity in...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-018-3225-8
更新日期:2018-11-01 00:00:00
abstract::Portal hypertension was observed in a 17-year-old girl with urticaria pigmentosa since 2 months of age. Liver biopsies showed portal and sinusoidal infiltration with mast cells although spleen biopsies showed only fibrosis. CONCLUSION. Portal hypertension is a complication of systemic mastocytosis that can lead to dea...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF01959789
更新日期:1995-10-01 00:00:00
abstract::The clinical presentation of combined pituitary hormone deficiency (CPHD) is variable. Some patients present with hypoglycemia during the neonatal period or during the first few years of life. Others present later in childhood with growth failure. We report on 7 patients with very late diagnosed severe hypopituitarism...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-019-03489-3
更新日期:2020-01-01 00:00:00
abstract::Female patients with congenital adrenal hyperplasia have been frequently studied in order to determine the impact of prenatal androgen exposure on various aspects of psychological, psychosocial and psychosexual development. There is no published study to evaluate the impact of the genital malformation, genital operati...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02276713
更新日期:1995-09-01 00:00:00
abstract::An immunocompetent 9-year-old boy with disseminated cat scratch disease involving spleen, cervical and abdominal lymph nodes, skull, and one clavicle is reported. Antibodies to Rochalimaea quintana and R. henselae were detected, at increasing, then decreasing concentration. DNA extracted from the biopsied skull lesion...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::The Kabuki (Niikawa-Kuroki) syndrome was reported in 1981 by Niikawa et al. and Kuroki et al. in a total of ten unrelated Japanese children with a characteristic array of multiple congenital anomalies and mental retardation. The syndrome is characterized by a distinct face, mild to moderate mental retardation, postnat...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF01983409
更新日期:1994-06-01 00:00:00
abstract:UNLABELLED:Convincing evidence of moderate hyperhomocysteinaemia as a risk factor for vascular disease has accumulated within the last decade being independent of conventional risk factors and equally strong as hypercholesterolaemia and smoking. A synergistic interaction with hypertension and smoking in their joint art...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/pl00014292
更新日期:1998-04-01 00:00:00
abstract::A case-control study was conducted to examine the association of beta-haemolytic non-group A streptococci and pharyngitis in a paediatric population (n = 502). No association could be found between disease and traditional Lancefield groups B, C, F, or G. When the analysis included the clustering of genetically related...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02026709
更新日期:1991-09-01 00:00:00
abstract::Adverse drug reactions (ADRs) are a significant problem in children, affecting one in ten children in hospital. Within the community, one in 500 children will experience an adverse drug reaction each year. Pharmacovigilance has been useful in detecting suspected ADRs. However, most ADRs are unreported and often not su...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s00431-012-1871-9
更新日期:2013-05-01 00:00:00
abstract:UNLABELLED:Endocrine dysfunction and damage of the epiphysial growth plates have been reported as late effects of antileukaemic treatment during childhood. It is a common opinion that cranial irradiation (CI) is the most important factor for blunted growth. Accordingly, recent therapeutic strategies in acute lymphoblas...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s004310050599
更新日期:1997-04-01 00:00:00
abstract::There is evidence pointing to a decrease of the glomerular filtration rate (GFR) in a subgroup of nephrotic children, likely secondary to hypovolemia. The aim of this study is to validate the use of urinary potassium to the sum of potassium plus sodium ratio (UK/UK+UNa) as an indicator of hypovolemia in nephrotic synd...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-017-3029-2
更新日期:2018-01-01 00:00:00
abstract::Gradenigo's syndrome (GS) is a rare disease characterised by the triad otitis media, pain in the region innervated by the first and the second division of trigeminal nerve and abducens nerve palsy. Septic sinus thrombosis is one of the most frequent and relevant complication of GS; it is often due to persistent damage...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-009-1047-4
更新日期:2010-04-01 00:00:00
abstract::Exchange transfusion using a peripheral artery and vein was carried out 18 times in 17 newborn infants. The arteries use to withdraw blood were the radial [13], the ulnar [3] an the posterior tibial [2]. Infusion of blood was carried out simultaneously through a peripheral vein. There was no mortality or morbidity dir...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00443258
更新日期:1981-11-01 00:00:00
abstract::Urinary tract infection (UTI) is a common bacterial infection among infants and children. Predicting which children with upper UTI will develop long-term sequelae remains difficult. We aimed at evaluating the predictive value of urine concentrations of interleukin-6 (UIL-6) and interleukin-8 (UIL-8) in subsequent rena...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-012-1914-2
更新日期:2013-06-01 00:00:00
abstract::Homeopathic globules are frequently used in children as a first-line treatment. Most of these globules are coated with sugar substitutes like xylitol; these substitutes are known for their laxative effect. Our patient shows that consumption of globules coated with xylitol does not have only laxative effects. It may ca...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-010-1249-9
更新日期:2010-12-01 00:00:00
abstract::Complex regional pain syndrome (CRPS) is a condition of unknown etiology characterized by autonomic, sensory, and motor disturbance. CRPS usually follows an injury in the affected limb, which is often trivial in nature. CRPS involving the facial region is rare, and there have been no previous descriptions in children....
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-013-2159-4
更新日期:2014-03-01 00:00:00
abstract:UNLABELLED:In neonates with pulmonary atresia and intact ventricular septum the aims of therapy are maintenance of pulmonary blood flow and right ventricular decompression in order to achieve right ventricular support of the pulmonary circulation. Recent developments in interventional heart catheterization with pulmona...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s004310050960
更新日期:1998-11-01 00:00:00
abstract:UNLABELLED:Increased breastfeeding was suggested as a contributing factor to significant hyperbilirubinemia. The aim of this study was to identify the risk factors associated with jaundice in exclusively breastfed term neonates. We retrospectively reviewed all consecutively live-born neonates from August 2009 to July 2...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-011-1512-8
更新日期:2012-01-01 00:00:00
abstract:UNLABELLED:Improved surgical care during the last decades, together with advances in medical management, led to a remarkable increase in survival of patients with congenital heart disease (CHD). However, aging of the CHD population brings new challenges, and loss of follow-up of adolescents and adults with CHD is a maj...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s00431-015-2557-x
更新日期:2015-07-01 00:00:00
abstract::Two newborns with congenital rubella syndrome are reported. Cranial sonography demonstrated bilateral cystic lesions in the subependymal germinal matrix. Congenital rubella and cytomegalovirus (CMV) infections are the most common proven causes of subependymal cysts of nonhaemorrhagic origin in the newborn. The sonogra...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441403
更新日期:1988-12-01 00:00:00
abstract::We compared epinephrine and dopamine as a first-line vasoactive drug in 40 neonates (enrolled in two gestational age strata ≤ 306/7 and ≥ 310/7 weeks) with fluid-refractory septic shock. Epinephrine or dopamine was initiated at 0.2 or 10 μg/kg/min, respectively. If shock persisted after 15 min, epinephrine or dopamine...
journal_title:European journal of pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00431-018-3195-x
更新日期:2018-09-01 00:00:00
abstract:UNLABELLED:We report on a 5-year-old girl with an unusually severe course of tick-borne encephalitis following passive immunization with specific hyperimmune globulin after a tick bite in an endemic area. Serial investigations of the CSF revealed intrathecal production of specific antibodies paralleled by increasing nu...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02002905
更新日期:1996-09-01 00:00:00
abstract::Most reviews on weight status have focused on obesity, and little information on underweight children is available. This review aimed to examine the prevalence and trends of underweight status among Asian children and adolescent populations in the last two decades. A systematic review of publications between the years...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s00431-012-1685-9
更新日期:2012-05-01 00:00:00
abstract::Recently a novel and non-invasive technique of lower leg length measurement (knemometry) was introduced. The method estimates the distance between heel and knee in the sitting child with an accuracy of 0.09 mm(SD). Two female patients with anorexia nervosa, aged 14:4 and 13:7 years, weighing minus 27 and minus 38% of ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02467353
更新日期:1987-11-01 00:00:00
abstract::The aim of this study was to determine whether macrosomia related to maternal diabetes alters lipoprotein metabolism and whether these abnormalities still persist or regress after 1 month of life. Serum lipoprotein compositions and concentrations as well as serum lipid fatty acid compositions were investigated in macr...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s004310051194
更新日期:1999-09-01 00:00:00