Continuous negative extrathoracic pressure and cardiac output--a pilot study.

Abstract:

:Continuous negative extrathoracic pressure (CNEP) has been recently reintroduced as therapy for respiratory failure. To determine its effects on cardiac output a pilot study was performed in ten patients aged 2 months-3 years (median 4 months). All had chronic respiratory failure (seven with bronchopulmonary dysplasia). Five were breathing spontaneously and five were intubated and undergoing intermittent positive pressure ventilation. Transcutaneous oxygen saturation and PCO2, together with ECG were continuously monitored. Pulmonary artery blood flow velocity was measured non-invasively using pulsed wave Doppler. The 95% confidence intervals for the changes with and without CNEP in spontaneously breathing and ventilated patients showed no statistically significant changes in heart rate, O2 saturation, transcutaneous PCO2 or cardiac output. This study shows that the use of CNEP, administered in a tank respirator, does not lead to large changes in cardiac output.

journal_name

Eur J Pediatr

authors

Raine J,Redington AN,Benatar A,Samuels MP,Southall DP

doi

10.1007/BF01954088

subject

Has Abstract

pub_date

1993-07-01 00:00:00

pages

595-8

issue

7

eissn

0340-6199

issn

1432-1076

journal_volume

152

pub_type

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