Abstract：
OBJECTIVE:The proposal of this study is to compare the efficacy of lisinopril and theophylline, alone or in association, on erythrocytosis in renal-transplanted patients. DESIGN:Prospectic, case-control study. PATIENTS/ENVIRONMENT: 15 inpatients meeting 3 main criteria: 1) ACE therapy for past erythrocytosis, 2) actual erythrocytosis, 3) symptomatic increase of haematocrit (Hct). INTERVENTION:The treatment has been divided into 3 consecutive phases of 30 days each: 1) lisinopril (5 mg/die), 2) theophylline (4 mg/kg/die), 3) association of 2 drugs. MEASUREMENTS:The evaluations were scheduled at the beginning and every month and consisted of renal function control, haemochromocytometric exam, serum level of folates, B12 vitamin and erythropoietin (EPO), iron level, cyclosporinemia, as well as clinic control and adverse events detection. RESULTS:A significative decrease of Hct values and a decrease of serum erythropoietin values was observed in patients treated with lisinopril. Patients treated with theophylline showed a significant reduction of Hct values causing a reduction of erythropoietin serum level in 8/13 patients. Lisinopril and theophylline administered in combination presented a significant decrease of Hct values, while EPO values diminished compared to basal values. CONCLUSIONS:These data showed that lisinopril is a valid therapy for the treatment of posttransplanted patients affected by erythrocytosis and, moreover, has the benefit of antihypertensive action. Theophylline remains an alternative therapy when ACEi are contraindicated. The combination of the 2 drugs doesn't produce additional benefits.
journal_name
Minerva Cardioangioljournal_title
Minerva cardioangiologicaauthors
D'Amelio A,Bonucchi D,Patruno P,Ballestri M,Mastrangelo Fsubject
Has Abstractpub_date
1997-11-01 00:00:00pages
567-72issue
11eissn
0026-4725issn
1827-1618journal_volume
45pub_type
临床试验,杂志文章,评审abstract：:Percutaneous coronary interventions (PCI) have gained widespread acceptation among cardiologists and among the general population for a variety of clinical indications, comprising from stable angina to ST-elevation acute myocardial infarction, due to the undisputed clinical benefit they provide and to their large avai...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2013-10-01 00:00:00
abstract：:Atrial fibrillation is the most common cardiac arrhythmia and the most frequent cause of hospitalization and utilization expense among all heart diseases. Taking into account persistent atrial fibrillation we know that, in order to cardiovert persistent atrial fibrillation, external direct current cardioversion is the...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2004-04-01 00:00:00
abstract：AIM:Paroxysmal supraventricular tachycardia (PSVT) is a very frequent type of arrhythmia. Atrioventricular nodal reciprocating tachycardia (AVNRT) and atrioventricular reciprocating tachycardia through extranodal accessory pathways (AVRT) are the most common types of paroxysmal supraventricular tachycardia. We describe...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2006-06-01 00:00:00
abstract：:The dilatation of the vascular grafts is a well known phenomenon. It is usually evaluated by means of ultrasounds or, in selected cases, by CT scans or MRI; nevertheless its characteristics are far beyond to be fully recognized. Following our promising preliminary experience with helical CT as sole preoperative imagin...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1996-05-01 00:00:00
abstract：:We report a case of a 86-year-old woman, with a 1-year history of pain during walking and standing; a duplex scanning of the popliteal fossa was performed bilaterally. We pointed out the presence of a bilateral popliteal vein aneurysm, partially thrombosed. She was treated only with oral anticoaugulant therapy, becaus...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1996-11-01 00:00:00
abstract：:Fragments of synthetic prostheses in knitted Dacron velour implanted years previously have been examined. Macrophages were found which fragment elements of the prostheses. It is concluded that synthetic knitted velour prostheses are biodegradable. ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：:With radioisotopes it is possible to study the heart obtaining complementary or substitutive informations to those provided by the most common noninvasive methods of myocardial assessment and by coronarography. This paper aim is to report experience with thallium 201 and 99mTc isonitrile in the diagnosis and followup ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：UNLABELLED:Currently, there are not reliable data on the incidence and prevalence of post-phlebitic syndrome (PTS) after an episode of asymptomatic postoperative deep vein thrombosis (DVT). In order to evaluate the epidemiology and the clinical course of PTS in patients who were submitted to hip and knee replacement, w...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：:The decision to offer patients with myocardial ischemia a coronary artery bypass graft (CABG) surgery has been largely determined by extent of coronary artery disease (CAD) and left ventricular function, since the early 1970's. Based upon subset analyses, and long-term follow-up, of three moderate-sized trials of stab...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2006-10-01 00:00:00
abstract：BACKGROUND:Aim of the present comparative clinical study was to demonstrate the efficacy of the topical application of mesoglycan, a profibrinolytic agent, for healing of leg ulcers in patients with chronic venous insufficiency. METHODS:Forty patients, observed in our outpatients department, with venous leg ulcers hav...
journal_title：Minerva cardioangiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：:Since its initial description by Gramiak and Shah in 1968, contrast echocardiography has become an established practice world-wide. Microbubbles have the unique property of being pure intravascular tracers. The basic rationale behind bubble imaging is the characteristic responses to ultrasound power that results in en...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2010-06-01 00:00:00
abstract：:Chronic venous insufficiency and chronic venous ulcers represent an important medical problem, because of the high incidence and prevalence in the general population, and need to be considered as a lifelong degenerative condition, with socioeconomic consequences. Ulceration is a severe complication of the post-thrombo...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2015-06-01 00:00:00
abstract：:Clopidogrel is an oral tyenopiridin with a central role in the management of acute coronary syndromes and after stent implantation. Despite the use of this drug, many patients continue to experience thrombotic events which are usually referred as "therapy failure". Actually, to date, only stent thrombosis is considere...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2013-12-01 00:00:00
abstract：AIM:The aim of the present study was to compare the safety and efficacy of amiodarone and procainamide in the acute cardiology setting. METHODS:The study population consisted of 223 patients with symptomatic atrial fibrillation (AF). After administration of digoxin for ventricular rate control, all patients who failed...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2007-08-01 00:00:00
abstract：:The best timing of orotracheal intubation and invasive ventilation in COVID-19 patients with acute respiratory distress syndrome is unknown. The use of non-invasive ventilation, a life-saving technique in many medical conditions, is debated in patients with ARDS since prolonged NIV and delayed intubation may be harmfu...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：10.23736/S0026-4725.20.05356-6
更新日期：2020-10-15 00:00:00
abstract：:The metabolic abnormalities associated with diabetes mellitus result in macrovascular and microvascular complications in multiple organ systems; it is the cardiovascular impact that accounts for the greatest morbidity and mortality associated with this disease. Heart failure, both with reduced and preserved systolic f...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2004-12-01 00:00:00
abstract：:The association between portal venous hypertension and pulmonary arterial hypertension has received scarce attention in the italian medical literature. Nevertheless the association is relatively frequent, it needs a multidisciplinary approach and it is a stimulus for the search of causes of so-called primary pulmonary...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：1996-07-01 00:00:00
abstract：:Congenital thrombophilia, specifically thrombophilia due to Leiden modified factor V as the cause of thromboembolic disease, is discussed. Thromboembolic disease is potentially fatal and disabling. A clinical case is presented of a girl of 15 with Leiden factor V thrombophilia in which all the typical thromboembolic e...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:Contrast enhanced computed tomography angiography (CTA) has seen rapid progress in its utility for the assessment of coronary artery disease (CAD) in the last few years. More and more technological enhancements have widened the horizons for the use of this non-invasive modality beyond its traditional role in assessmen...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2013-02-01 00:00:00
abstract：:Our previous researches proved that, in patients affected by Raynaud disease, microcirculatory alterations were greater in those cases in which the small vessels showed evocative appearances of a sclerodermatous connectivopathy. In this study we evaluated cutaneous microvasculature in 18 patients suffering from clear ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：:The PAP/PEA (Prevalence of Early Atherosclerosis) study aims to define the prevalence of subclinical atherosclerosis in a typical population of central Italy. A concomitant study evaluates the prevalence of venous diseases. The first group of 850 patients evaluated, indicated the prevalence of superficial ve-nous dise...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1997-05-01 00:00:00
abstract：:The Authors report their experience of the surgical treatment of cardiac prosthetic endocarditis. Between September 1974 and December 1988, 2,796 cardiac prostheses were implanted. An endocarditis in the follow-up of 23 patients involving 27 prostheses was diagnosed. The operative mortality was high in patients with m...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
abstract：:Hypertrophic cardiomyopathy is a disease characterised by massive ventricular hypertrophy, reduced diastolic function and excessive ventricular contraction. It involves sections of both ventricles, but in particular the left ventricle. Although it was initially thought that this pathology might depend on a modified sy...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1990-12-01 00:00:00
abstract：AIM:Drug-coated balloon (DCB) technology has emerged as a promising therapy particularly in the treatment of coronary in-stent restenosis. Although a variety of devices are available for clinical use, clinical outcomes have been variable and scope for significant improvement exists. METHODS:In a preclinical study, a t...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2012-10-01 00:00:00
abstract：:In the period 1972-1988, 209 patients (81 males, 128 females, mean age 42.4 +/- 11.9, range 20-71 years) underwent surgery for multiple valve repair (MVR) at the Italian Institution of Cardiac Surgery. Ninety-five patients had previously undergone mitral commissurotomy (MC). NTHA function class was III-IV in 89% of th...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：:The Post-CABG trial was designed to assess the effects of 2 different lipid lowering strategies and low dose warfarin vs placebo (2 x 2 factorial) design on the progression of atherosclerosis in saphenous vein grafts. Atherosclerotic progression was determined by comparing baseline and follow-up angiograms (mean inter...
journal_title：Minerva cardioangiologica
pub_type： 临床试验,杂志文章,评审
doi：
更新日期：2002-08-01 00:00:00
abstract：AIM:We aimed to investigate the effects of verapamil and adenosine in an adjunct to intravenous tirofiban on management and prognosis of no-reflow phenomenon during primary percutaneous coronary intervention (PPCI) and to compare their efficacies on reversing of no-reflow phenomenon and short and midterm survival. MET...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2014-10-01 00:00:00
abstract：AIM:The aim of this study was to assess cardiac mortality in patients with reduced ejection fraction (EF< or =45%) and anemia (Hb< or =12 g/dL) undergoing coronary stenting and to investigate whether iron-deficiency anemia influenced outcome when compared to non-anemic patients or patients with other types of anemia. ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2010-02-01 00:00:00
abstract：:Atrial fibrillation (AF) is the most common observed cardiac arrhythmia and is the most frequent condition associated with thromboembolic events in patients with or without mitral valve disease. The source of cardiac emboli is the left atrium, the left atrial appendage or, less frequently, the left ventricle. Emboli m...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2003-06-01 00:00:00
abstract：BACKGROUND:Aim of this registry study was the evaluation of the stability of carotid plaques by ultrasound in asymptomatic subjects with high oxidative stress following supplementation with a combination of the extract from bark of Pinus pinaster, Pycnogenol®, with an extract from Centella asiatica leaves, Centellicum®...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2016-12-01 00:00:00
