Abstract:
AIM:The aim of the present study was to compare the safety and efficacy of amiodarone and procainamide in the acute cardiology setting. METHODS:The study population consisted of 223 patients with symptomatic atrial fibrillation (AF). After administration of digoxin for ventricular rate control, all patients who failed to restore sinus rhythm (SR) were randomized into 2 groups: group A (113 patients) were administered 300 mg amiodarone intravenously over 30 min and, in case of failure to restore SR, amiodarone of 20 mg/kg/24 h was administered intravenously. Group B (110 patients) were intravenously administered a bolus dose of 1 gm procainamide, at an infusion rate 50/mg/min, and, in case of failure to restore SR, 2 mg/min for the next 24 h. RESULTS:The rate of cardioversion to SR was similar between amiodarone (81.4%) and procainamide (82.7%) (P=NS). Procainamide loading recorded faster cardioversion times than amiodarone loading (P=0.02), but there was no significant difference after that. Amiodarone caused a significant decrease on systolic blood pressure compared to procainamide for the first 18 h (P<0.001), and a significant decrease in the diastolic blood pressure for the first 6 h (P<0.001). Side-effects for either medication were sparse. The only real prognostic factor for successful cardioversion remains the size of left atrium. CONCLUSION:Both drugs were equally effective in restoring SR, though procainamide acts quicker in the loading phase. Both medications are safe and side effects develop only in the maintenance phase.
journal_name
Minerva Cardioangioljournal_title
Minerva cardioangiologicaauthors
Xanthos T,Prapa V,Papadimitriou D,Papadimitriou Lsubject
Has Abstractpub_date
2007-08-01 00:00:00pages
433-41issue
4eissn
0026-4725issn
1827-1618journal_volume
55pub_type
杂志文章,随机对照试验abstract:AIM:The aim of this study was to evaluate the effects of low-dose niacin extended-release (niacin-ER) combined with simvastatin (SV) in the treatment of patients with mixed dyslipidemia who have not normalized their lipid profile with statin therapy alone. METHODS:A prospective, clinical trial of 35 patients with mixe...
journal_title:Minerva cardioangiologica
pub_type: 临床试验,杂志文章
doi:
更新日期:2010-10-01 00:00:00
abstract::Radial approach has been used since 1989 to perform coronary angiography as an alternative to femoral access. During past decades, the development of dedicated equipment has led to high efficacy also in complex procedures. ST elevation myocardial infarction (STEMI) is known to be a high bleeding risk setting and in tu...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
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abstract::The transradial access (TRA) for cardiac catheterization and percutaneous coronary intervention (PCI) has been widely adopted in the last decades since its first description in the late forties. The transradial approach has been associated with favourable outcomes as compared with transfemoral access (TFA) in several ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.20.05391-8
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journal_title:Minerva cardioangiologica
pub_type: 临床试验,杂志文章,评审
doi:
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abstract::Although drug-eluting stents (DES) have significantly reduced the rates of restenosis as compared to bare metal stents, late stent thrombosis remains a major drawback, especially for "off-label" use. Delayed arterial healing, characterized by persistent fibrin deposition and poor endothelialization, has been shown to ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.20.05347-5
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abstract::Cell based therapy has become a new and attractive option for the treatment of cardiac disease and heart failure. Although it has been demonstrated in vitro and in vivo that differentiation of non-differentiated cells (progenitor cells) into cardiomyocytes is able even in adult hearts the potential use of such transdi...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
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更新日期:2009-04-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,meta分析,评审
doi:
更新日期:2009-06-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2000-06-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2010-06-01 00:00:00
abstract::Congenital thrombophilia, specifically thrombophilia due to Leiden modified factor V as the cause of thromboembolic disease, is discussed. Thromboembolic disease is potentially fatal and disabling. A clinical case is presented of a girl of 15 with Leiden factor V thrombophilia in which all the typical thromboembolic e...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract::Thrombophilia is characterised by elevated thrombotic and embolic risk and may be caused by congenital or acquired coagulating inhibitor deficit. A young man was repeatedly admitted to Emergency Medicine Units because of pain, oedema and slight functional impairment of the left leg, and recurrent thrombophlebitis was ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4725.18.04678-9
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
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abstract:: ...
journal_title:Minerva cardioangiologica
pub_type: 信件
doi:10.23736/S0026-4725.19.04916-8
更新日期:2019-10-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 临床试验,杂志文章
doi:
更新日期:1997-01-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2009-08-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.20.05203-2
更新日期:2020-10-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2007-10-01 00:00:00
abstract::Significant variations in the ECG have been observed in a female aged 77 with heart failure and chronic atrial fibrillation during an occasional increase in blood potassium followed by normalization. The major phenomena observed during hyperkalemia, due to a severe dehydration, were a transient sinus rhythm with atrio...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:1997-06-01 00:00:00
abstract::In patients with atrial fibrillation (AF) warfarin has been the mainstay therapy for stroke prevention. In recent randomized clinical trials (RCTs) oral direct thrombin inhibitor (Dabigatran) and factor Xa inhibitors (Rivaroxaban and Apixaban) challenged the efficacy and safety benchmarks set by warfarin. These drugs ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2012-08-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 临床试验,杂志文章
doi:
更新日期:1997-07-01 00:00:00