Abstract:
:The Post-CABG trial was designed to assess the effects of 2 different lipid lowering strategies and low dose warfarin vs placebo (2 x 2 factorial) design on the progression of atherosclerosis in saphenous vein grafts. Atherosclerotic progression was determined by comparing baseline and follow-up angiograms (mean interval: 4.3 years) using quantitative angiography. Significant progression of disease in SVG's was reduced with the aggressive lipid lowering strategy compared to the moderate strategy; significant progression in SVG's was not altered by low dose warfarin. The beneficial effects on angiographic changes were demonstrated in multiple subgroups of participants in the trial. The composite clinical end point of death, MI, stroke, PTCA or repeat CABG was analyzed at the end of the trial and 3 years (extended follow-up) after closure of the angiographic trial. At the time of the extended follow-up the aggressive lipid strategy was associated with reduced clinical events; low dose warfarin was also associated with reduced clinical events.
journal_name
Minerva Cardioangioljournal_title
Minerva cardioangiologicaauthors
Hoogwerf BJ,Hunninghake DB,Knatterud G,Campeau Lkeywords:
subject
Has Abstractpub_date
2002-08-01 00:00:00pages
291-9issue
4eissn
0026-4725issn
1827-1618journal_volume
50pub_type
临床试验,杂志文章,评审abstract::Radial approach has been used since 1989 to perform coronary angiography as an alternative to femoral access. During past decades, the development of dedicated equipment has led to high efficacy also in complex procedures. ST elevation myocardial infarction (STEMI) is known to be a high bleeding risk setting and in tu...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2016-06-01 00:00:00
abstract::Two hundred and one patients admitted to Coronary Care Unit with documented acute myocardial infarction, whose chest pain had occurred within 12 hours of hospital admission non thrombolised, were studied. The peak of creatine kinase (CK) was examined and compared between patients without previous manifestations of myo...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract:AIM:To evaluate any differences in ventricular pre-excitation secondary to Wolff Parkinson White syndrome in the aged compared to young and adult patients. METHODS: EXPERIMENTAL DESIGN:a clinical study was performed using a comparative prospective criterion with retrospective analysis. The duration of follow-up range...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00
abstract:AIM:Glomerular filtration rate (GFR) is commonly calculated using the modification of diet in renal disease (MDRD) and Cockroft-Gault (CG) formulas and recently by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) algorithm and not directly measured, so that the real impact of antihypertensive therapy on ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:To analyze the usefulness of autologous blood salvage and intraoperative isovolemic hemodilution in conjunction with autologous blood salvage in cardiac surgery, and also to compare two different autologous blood salvage methods. EXPERIMENTAL DESIGN:Retrospective analysis of transfusion practice in cardiac s...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:The purpose of this registry is to report the immediate and long-term safety and efficacy of the Biotronik Orsiro stent in an unselected population during everyday practice. METHODS:Between May 2012 and June 2013, 246 consecutive coronary angioplasty procedures were performed using at least one Orsiro drug-...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2016-02-01 00:00:00
abstract::The aim of this study was to provide a further contribution to the study on the alterations of left ventricular diastolic function induced by dialysis, using simple indexes of diastolic function obtained with Doppler. The study is conduced in 15 patients with renal failure aged between 22 and 51 years old by means of ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract::Chronic vascular disorders of the upper limbs are not frequently encountered in women; in addition, advanced age of onset tends to suggest the presence of common diseases such as arteriosclerosis or microembolization. Nonetheless, diagnosis is not always straightforward and in some cases both-laboratory and instrument...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract::The Impella left ventricular support system consists of two main components: a family of different ventricular support catheters with a microaxial pump to be placed across the aortic valve and a single external controller which is connected to activate and control the pump function. Four Impella left ventricular suppo...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4725.18.04703-5
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:The aim of this prospective supplement summer registry study was to evaluate the efficacy of Pycnogenol® in controlling symptoms of chronic venous insufficiency (CVI) and microcirculatory parameters: venous hypertension and microangiopathy. Pycnogenol® (Horphag Research) is the standardized extract of the ba...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.19.04948-X
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Sutureless aortic valve prostheses have the potential to augment the adoption of alternative incision approaches for aortic valve replacement (AVR). Still, we lack the evidence on which surgical approach is best associated with sutureless AVR. METHODS:Data on 483 patients undergoing sutureless small incisio...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.17.04568-6
更新日期:2018-04-01 00:00:00
abstract::The dilatation of the vascular grafts is a well known phenomenon. It is usually evaluated by means of ultrasounds or, in selected cases, by CT scans or MRI; nevertheless its characteristics are far beyond to be fully recognized. Following our promising preliminary experience with helical CT as sole preoperative imagin...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1996-05-01 00:00:00
abstract:BACKGROUND:Galectin-3 is a recently developed biomarker of fibrosis, which may play a role in cardiac remodeling and associated with both the progression and severity of heart failure (HF). METHODS:A prospective cohort study of 190 patients with documented prior myocardial infarction and chronic HF (NYHA class II-IV) ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to define a correct anesthesiological and surgical approach in patient who present a significant carotid stenosis with contralateral carotid occlusion. METHODS:Between 1996 and 1998 in our Department of Vascular Surgery of the Hospital S. Giovanni Battista has been executed 337...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
abstract::Stenting of symptomatic myocardial bridges is a therapeutic option with documented good short-term outcome. However, limited data on the long term outcome of myocardial bridge stenting has shown a higher restenosis rate comparing to stenting of de novo atherosclerotic lesions. Drug-eluting stenting of de novo atherosc...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2007-12-01 00:00:00
abstract::In order to assess left ventricular structure and diastolic function, 50 hypertensive male subjects, 25 with and 25 without a history of alcohol abuse, and 20 normotensive male controls underwent Doppler echocardiographic examination followed by ambulatory blood pressure monitoring for 24 hours. Left ventricular mass ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1993-07-01 00:00:00
abstract::In obesity, the systemic resistances (SR) are reduced while the blood volume is increased. The rise of cardiac output (CO), stress-induced, produces an increase in blood pressure (BP), as an hypertensive behavior of the stress-response. The aim of our study is to evaluate if, in obese subjects, the considerable increa...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::Atrial fibrillation is the most common cardiac arrhythmia and the most frequent cause of hospitalization and utilization expense among all heart diseases. Taking into account persistent atrial fibrillation we know that, in order to cardiovert persistent atrial fibrillation, external direct current cardioversion is the...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2004-04-01 00:00:00
abstract:UNLABELLED:Currently, there are not reliable data on the incidence and prevalence of post-phlebitic syndrome (PTS) after an episode of asymptomatic postoperative deep vein thrombosis (DVT). In order to evaluate the epidemiology and the clinical course of PTS in patients who were submitted to hip and knee replacement, w...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1997-03-01 00:00:00
abstract::A case of double unruptured intracranial aneurysm associated with aortic coarctation is presented. The main characteristics of the unusual association, the diagnostic criteria and the surgical strategies are reviewed. ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::The effectiveness of a new alpha-blocking agent with additional mechanism of action was evaluated during intraoperative hypertensive crises. Urapidil was administered both in bolus form and as a continuous infusion in order to compare the two routes of delivery. During the study systolic, diastolic, mean pressure and ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract:UNLABELLED:To test if a low Q wave voltage and its faulty increase after exercise is an additional sign of myocardial ischemia, 64 pts with no previous myocardial infarction, bundle branch block or left ventricular hypertrophy were studied by a treadmill test and coronary angiography. Nineteen had single vessel disease...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:1989-06-01 00:00:00
abstract::Palliative care is an alternate therapeutic approach that involves specialised medical care of a patient diagnosed with serious life threatening illness like heart failure (HF). The prime aim of the palliative care is to provide patient with relief from the symptoms, pain, physical stress, and mental stress of the dia...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2016-02-01 00:00:00
abstract:AIM:The aim of this study was to describe the five-year prognosis of an Italian cohort of patients following acute myocardial infarction (AMI) occurred at age ≤ 45 years and to investigate the potential role of risk predictors for future cardiovascular events (CVE). METHODS:The study enrolled 112 consecutive patients ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2010-08-01 00:00:00
abstract:AIM:To evaluate the relationship between body mass index (BMI), body fat distribution and some coronary heart disease risk factors like hyperlipidemia, hypertension and cigarette smoking. STUDY DESIGN:Cross-sectional. PLACE:Tiriolo, a little town close to Catanzaro, of prevalent rural economy. PARTICIPANTS:Volunteer...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract::Drug-coated balloons (DCB) are widely used for several types of coronary artery disease, especially in-stent restenosis and de-novo small vessel disease. The role of correct lesion preparation is of paramount importance before DCB use. In the last years, the use of scoring balloons to achieve this goal has emerged as ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4725.19.05091-6
更新日期:2020-02-01 00:00:00
abstract:AIM:The purpose of this paper was to verify whether there is any sign of involvement of the cardiovascular system in the early stages of collagen diseases. METHODS:Seventeen patients (10 female and 7 male, average age 41.35 +/- 9.85 years) (group A) recruited at the Ambulatory of Internal Medicine for suspected collag...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2006-02-01 00:00:00
abstract:AIM:Coronary artery disease (CAD) is a leading cause of morbidity and mortality in the developed world and is rapidly assuming epidemic proportions in developing countries, including India. Extensive research has proven the role of multiple etiologies such as dyslipidemia, inflammation, endothelial dysfunction and insu...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2011-04-01 00:00:00
abstract::The PAP/PEA (Prevalence of Early Atherosclerosis) study aims to define the prevalence of subclinical atherosclerosis in a typical population of central Italy. A concomitant study evaluates the prevalence of venous diseases. The first group of 850 patients evaluated, indicated the prevalence of superficial ve-nous dise...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract:BACKGROUND:The aim of this study was to correlate uric acid levels with the classic cardiovascular risk factors in an adult population in Campania. METHODS:The following parameters were assessed in the study population (600 men and 600 women) aged between 25-74 years old, subdivided into 5 age groups (25-34, 35-44, 45...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00