Abstract:
BACKGROUND:Sutureless aortic valve prostheses have the potential to augment the adoption of alternative incision approaches for aortic valve replacement (AVR). Still, we lack the evidence on which surgical approach is best associated with sutureless AVR. METHODS:Data on 483 patients undergoing sutureless small incision AVR between 2010-2014 in two European institutions (207 with ministernotomy [MS] and 276 via right anterior minithoracotomy [RAMT]) have been retrospectively analyzed. After propensity score matching, 160 pairs of patients have been selected. RESULTS:No significant difference for in-hospital mortality was observed between MS and RAMT (P=0.12). Both perfusion and aortic cross-clamping times were longer in RAMT group (P<0.0005). Lower incidence of third degree atrioventricular block requiring pacemaker implantation (P=0.04), shorter ventilation times (P<0.0005) and less requirement for pleural drainage/thoracentesis (P=0.007) have been registered in the RAMT group. Follow-up was shorter for RAMT group (14.6 vs. 21.7 months, P<0.0005). Survival by Kaplan-Meier was comparable both for unmatched (P=0.79) and matched (P=0.90) cohorts. Cox regression analysis showed no statistically significant difference for mid-term survival between the two approaches (P=0.95 for intercohort comparison [MS vs. RAMT]). Mid-term survival by Cox multivariable proportional hazards regression model was associated with two independent predictors: preoperative left ventricular ejection fraction (P=0.021) and prolonged (>24 h) assisted ventilation (P=0.001). CONCLUSIONS:Small incision sutureless AVR through both partial sternotomy and right anterior minithoracotomy provides excellent clinical outcomes. Right anterior minithoracotomy, though associated with longer operative times compared to partial sternotomy, may result in less perioperative morbidity, with no difference in early and mid-term survival.
journal_name
Minerva Cardioangioljournal_title
Minerva cardioangiologicaauthors
Gilmanov D,Solinas M,Santarpino G,Farneti PA,Murzi M,Fischlein T,Pfeiffer Sdoi
10.23736/S0026-4725.17.04568-6subject
Has Abstractpub_date
2018-04-01 00:00:00pages
170-179issue
2eissn
0026-4725issn
1827-1618pii
S0026-4725.17.04568-6journal_volume
66pub_type
杂志文章abstract::The efficacy and safety of the treatment of arterial hypertension with the ACE-inhibitor quinapril, were evaluated in a multicentre study conducted in Italy. The study, lasting 14 weeks, after a preliminary wash-out period, allowed response-based titration of quinapril dose from 10 mg to 40 mg once a day, with provisi...
journal_title:Minerva cardioangiologica
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:1992-03-01 00:00:00
abstract::Three hundred carotid plaques (stenosis 45 to 65%) in 300 asymptomatic patients were included into a follow-up study considering three ultrasound types of plaques: type 1, non echogenic; type 2 intermediate, partially echogenic and type 3 highly echogenic. Types 1 and 2 had regular contour/surface while type 3 was irr...
journal_title:Minerva cardioangiologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1992-07-01 00:00:00
abstract:AIM:In mitral stenosis (MS) patients with a poor symptom-echocardiography correlation, dobutamine stress echocardiography (DSE) still does not have a confirmed utility and predictive value. Our aim is to evaluate usefulness of DSE in assessing 2 and 5 years clinical outcomes. METHODS:Forty-four consecutive patients wi...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:Adjuvant trastuzumab therapy increases survival rates in patients with early HER2-positive breast cancer, although it can be potentially cardiotoxic. The aim of this study was to evaluate the prevalence of left ventricular (LV) systolic dysfunction; and the relationship between the presence of cardiovascular...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.16.04278-X
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Ablation of ventricular tachycardia is the main therapy for patients with drug-refractory VT. Although evidence suggests that VT ablation could lower the incidence of recurrent VT, many cases still develop VT in follow-up. In this study, we performed a systematic review and meta-analysis to examine risk fact...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.20.05128-2
更新日期:2020-09-29 00:00:00
abstract:OBJECTIVES:To examine the relationship between patients gender, age and the development of different types of internal carotid artery plaque. DESIGN:Prospective open clinical study. METHODS:455 carotid duplex scans with a greater than 50% stenosis were analysed in terms of gender, age, degree of stenosis symptoms and...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract::Radial approach has been used since 1989 to perform coronary angiography as an alternative to femoral access. During past decades, the development of dedicated equipment has led to high efficacy also in complex procedures. ST elevation myocardial infarction (STEMI) is known to be a high bleeding risk setting and in tu...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2016-06-01 00:00:00
abstract::Renal denervation is a novel catheter based approach that has been shown to effectively lower blood pressure in patients with resistant hypertension. Small studies have shown additional benefits in patients being treated for hypertension, such as improvements in insulin sensitivity, sleep apnoea and arrhythmias. More ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2013-06-01 00:00:00
abstract::The authors present the results of a research on 3,888 patients (1,768 males and 2,120 females) admitted to the 1st Internal Medicine Department of Leghorn Hospital during two years (from July 1993 to June 1995). The research is intended to value the hyperlipidaemia's incidence in hospitalized patients, and the associ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::Saphenous vein is nowadays the material of choice performing on femoro-distal revascularisation; when this is not available, it is important to use a material which gives the closest approximation of an ideal conduit and for same time an easy handling during the execution of the anastomosis. Although vein's degenerati...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract::As echocardiography is being used more often, its value and accuracy are becoming more fully appreciated, especially for identifying normal anatomic variants and their possible erroneous interpretation as pathologic states. We report the echocardiographic and clinical findings observed in sixteen subjects examined at ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1989-07-01 00:00:00
abstract:AIM:In-stent restenosis still affects 10-50% of long-term outcome after percutaneous coronary intervention (PCI). Large clinical trials have shown that sirolimus-eluting stents (SES) have reduced restenosis rate to 0-9% in lesions at low-moderate risk. The aim of this study was to evaluate long-term clinical and angiog...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2004-06-01 00:00:00
abstract::The Authors describe a case of a patient showing, during an episode of chest pain, an ecg-pattern of wide and tall "Q" wave simulating inferior myocardial infarction. In fact, a further ecg recorded during sinus rhythm denotes that the "Q" wave was a retrograde P wave generated by a nodal rhythm. The other known cause...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::Transcatheter aortic valve implantation (TAVI) is the treatment of choice among patients with symptomatic severe aortic stenosis (AS) deemed inoperable and a valuable alternative to surgical aortic valve replacement for high-risk surgical patients. Over the years, this procedure proved to be relatively safe, but despi...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2016-06-01 00:00:00
abstract::Our previous researches proved that, in patients affected by Raynaud disease, microcirculatory alterations were greater in those cases in which the small vessels showed evocative appearances of a sclerodermatous connectivopathy. In this study we evaluated cutaneous microvasculature in 18 patients suffering from clear ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND:Unstable angina implies high risk of myocardial infarction and sudden death. Increased levels of cytoplasmatic enzymes and proteins (creatine phosphokinase, MB creatine phosphokinase troponin T, etc.) were described in unstable angina, providing information about incoming major coronary events. Cardiac tropo...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract::This report describes a rare case of concurrent abdominal aortic aneurysm and bilateral renal ectopia. Preoperative work-up included intravenous pyelography and angiography to assess renal function, renal artery anatomy, and ureter position. Conventional surgery was performed without renal protection. No deterioration...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2008-10-01 00:00:00
abstract::Drug-coated balloons (DCB) are widely used for several types of coronary artery disease, especially in-stent restenosis and de-novo small vessel disease. The role of correct lesion preparation is of paramount importance before DCB use. In the last years, the use of scoring balloons to achieve this goal has emerged as ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4725.19.05091-6
更新日期:2020-02-01 00:00:00
abstract::Cardiovascular diseases are the major cause of morbidity and mortality in the Western countries and their prevalence is increasing in developing world. The final biological evolution of atherosclerotic process, supporting development and progression of cardiovascular diseases, is thrombosis. In the most recent years s...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2005-12-01 00:00:00
abstract::The division of the venous circulation in to two sectors, one constituted by the superficial and deep venous trunks (macrocirculation) and the other by the capillaries and precapillary venules (microcirculation), is surely schematical but aids the comprehension of many hemodynamic effects connected to hampered venous ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:1992-11-01 00:00:00
abstract:AIM:Glomerular filtration rate (GFR) is commonly calculated using the modification of diet in renal disease (MDRD) and Cockroft-Gault (CG) formulas and recently by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) algorithm and not directly measured, so that the real impact of antihypertensive therapy on ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2014-08-01 00:00:00
abstract::Aneurysms are a later consequence of acute myocardial infarction, developing in about 20% of patients with transmural infarcts. Pathologically aneurysms have two general forms: the first type has large endocardial fibroelastosis overlying the infarct size, the second type contains little or no endocardial fibroelastos...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract::In a controlled study of 100 patients, mean age 65 years old, suffering from chronic peripheral obliterative arterial disease, Leriche's stage II, were randomised in two groups treated respectively with defibrotide (400 mg bid) or heparan-sulfate (40 mg bid) by the oral route for a period of 6 months. At basal and aft...
journal_title:Minerva cardioangiologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Infection due to severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), i.e. coronavirus-associated disease 2019 (COVID-2019), may occasionally lead to acute respiratory distress syndrome (ARDS), requiring in the most severe cases extracorporeal membrane oxygenation (ECMO). Yet, limited data, if any, ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.20.05328-1
更新日期:2020-10-01 00:00:00
abstract::The Post-CABG trial was designed to assess the effects of 2 different lipid lowering strategies and low dose warfarin vs placebo (2 x 2 factorial) design on the progression of atherosclerosis in saphenous vein grafts. Atherosclerotic progression was determined by comparing baseline and follow-up angiograms (mean inter...
journal_title:Minerva cardioangiologica
pub_type: 临床试验,杂志文章,评审
doi:
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:The deep femoral artery provides the primary blood supply to the thigh, and in addition serves as the major collateral channel for bypassing the obstructed superficial femoral artery. The purpose of isolated profundoplasty is to relieve a significant stenosis and improve perfusion of the ischaemic leg. METH...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVE:The proposal of this study is to compare the efficacy of lisinopril and theophylline, alone or in association, on erythrocytosis in renal-transplanted patients. DESIGN:Prospectic, case-control study. PATIENTS/ENVIRONMENT: 15 inpatients meeting 3 main criteria: 1) ACE therapy for past erythrocytosis, 2) actua...
journal_title:Minerva cardioangiologica
pub_type: 临床试验,杂志文章,评审
doi:
更新日期:1997-11-01 00:00:00
abstract::Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19) which recently has been characterized as a pandemic by the World Health Organization (WHO) having killed almost 250,000 people worldwide as of May 4th, 2020. Despite the fact that SARS-CoV-2 seem...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4725.20.05298-6
更新日期:2020-08-01 00:00:00
abstract::Fragments of synthetic prostheses in knitted Dacron velour implanted years previously have been examined. Macrophages were found which fragment elements of the prostheses. It is concluded that synthetic knitted velour prostheses are biodegradable. ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract:BACKGROUND:High sensitivity cardiac troponins I (hs-cTnI) and T (hs-cTnT) and natriuretic peptides (BNP and NT-proBNP) are universally recognized as cardiac reference biomarkers in patients with acute coronary syndromes and heart failure respectively. However, while on one hand the high sensitivity methods of cardiac b...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.20.05281-0
更新日期:2020-08-01 00:00:00