[Effectiveness of mesoglycan topical treatment of leg ulcers in subjects with chronic venous insufficiency].

Abstract:

BACKGROUND:Aim of the present comparative clinical study was to demonstrate the efficacy of the topical application of mesoglycan, a profibrinolytic agent, for healing of leg ulcers in patients with chronic venous insufficiency. METHODS:Forty patients, observed in our outpatients department, with venous leg ulcers have been randomized in two groups of twenty subjects, each treated with topical application of mesoglycan (1 or 2 vials/day) or vegetal stimulins and followed for two months, with controls after 15, 30 and 60 days. RESULTS:At the end of the observation period, ulcer healing rate was 95% in the mesoglycan group, while a lower healing rate was obtained in the stimulins group (80%). CONCLUSIONS:The present study confirms previous clinical experiences with mesoglycan and suggests its application in the topical treatment of venous ulcers.

journal_name

Minerva Cardioangiol

authors

La Marca G,Pumilia G,Martino A

keywords:

subject

Has Abstract

pub_date

1999-09-01 00:00:00

pages

315-9

issue

9

eissn

0026-4725

issn

1827-1618

journal_volume

47

pub_type

临床试验,杂志文章
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    authors: Kiernan TJ,Kiernan GD,Yan BD

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    doi:

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    pub_type: 杂志文章

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    doi:

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  • Chronic venous insufficiency and venous microangiopathy: management with compression and Pycnogenol®.

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  • Biodegradable-polymer-based drug-eluting stent for left main coronary artery disease.

    abstract::Percutaneous coronary interventions (PCI) have gained widespread acceptation among cardiologists and among the general population for a variety of clinical indications, comprising from stable angina to ST-elevation acute myocardial infarction, due to the undisputed clinical benefit they provide and to their large avai...

    journal_title:Minerva cardioangiologica

    pub_type: 杂志文章,评审

    doi:

    authors: Gutiérrez-Chico JL,Jochheim D,Mehilli J

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  • [Clinical course and incidence of post-thrombophlebitic syndrome after profound asymptomatic deep vein thrombosis. Results of a transverse epidemiologic study].

    abstract:UNLABELLED:Currently, there are not reliable data on the incidence and prevalence of post-phlebitic syndrome (PTS) after an episode of asymptomatic postoperative deep vein thrombosis (DVT). In order to evaluate the epidemiology and the clinical course of PTS in patients who were submitted to hip and knee replacement, w...

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    authors: Siragusa S,Beltrametti C,Barone M,Piovella F

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  • [Inflammation, atherosclerosis and acute coronary syndromes].

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    pub_type: 杂志文章

    doi:

    authors: Biasucci LM,Santamaria M,Liuzzo G

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  • [Myocardial infarct without Q wave in the elderly: diagnostic evaluation using vectorcardiography].

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    journal_title:Minerva cardioangiologica

    pub_type: 杂志文章,评审

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    authors: Tedesco MA,Ratti G,Aquino D,Sarubbi B,Irace L,Giasi A,Cice G,Coppolino P,Iacono A

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  • [Verapamil in the cardioversion of atrial fibrillation. Clinical study].

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    doi:

    authors: Martinelli MM,Dragagna G,Vitali A,Fedele F

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  • [Cholesterol fractions in subjects with cerebral, coronary and peripheral vasculopathy].

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    journal_title:Minerva cardioangiologica

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    authors: Ferlito S,Ricceri M,Di Mauro C

    更新日期:1989-01-01 00:00:00

  • How to use the C-reactive protein in cardiac disease?

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    authors: Ursella S,Mazzone M,Portale G,Testa A,Pignataro G,Covino M,Fenici P,Gasbarrini GB,Gentiloni Silveri N

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    journal_title:Minerva cardioangiologica

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    doi:

    authors: Hassell ME,Grundeken MJ,Delewi R,Wykrzykowska JJ,Piek JJ

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    pub_type: 杂志文章

    doi:

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    更新日期:1990-05-01 00:00:00

  • [Changes in the left ventricular function in hemodialyzed patients. Role of Doppler echocardiography].

    abstract::The aim of this study was to provide a further contribution to the study on the alterations of left ventricular diastolic function induced by dialysis, using simple indexes of diastolic function obtained with Doppler. The study is conduced in 15 patients with renal failure aged between 22 and 51 years old by means of ...

    journal_title:Minerva cardioangiologica

    pub_type: 杂志文章

    doi:

    authors: Cavarra M,Lo Giudice P,Statella P,Liuzzo G,Circo A

    更新日期:1993-09-01 00:00:00

  • Abdominal aortic aneurysm associated with renal ectopia.

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    journal_title:Minerva cardioangiologica

    pub_type: 杂志文章

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    authors: Bianco G,Micheletti E,Silvestri F,Laezza F,Platì S,Mauro G,Scotto Di Uccio A,De Donato G

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  • [Deficit of anticoagulant factors, endothelial stress and thrombophilia].

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    doi:

    authors: Neri S,Ierna D,Sfogliano L

    更新日期:1997-10-01 00:00:00

  • [Iatrogenic torsade de pointes induced by thioridazine].

    abstract::Torsade de pointes is a form of polymorphous ventricular tachycardia in which the polarity of the QRS complex exhibits phasic alterations in both axis. Traditionally, torsade de pointes has been described in association with a congenital or acquired (including drug and metabolic) causes of QT prolongation. Clinical ou...

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    更新日期:1992-06-01 00:00:00

  • [Botallo's duct with pulmonary hypertension in the adult].

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