Abstract：
AIM:In mitral stenosis (MS) patients with a poor symptom-echocardiography correlation, dobutamine stress echocardiography (DSE) still does not have a confirmed utility and predictive value. Our aim is to evaluate usefulness of DSE in assessing 2 and 5 years clinical outcomes. METHODS:Forty-four consecutive patients with known MS were submitted, between April 1998 and July 1999, to basal and DSE. Patients were divided in 2 groups: group A if during DSE was reached a mean mitral gradient (MG) = or > 15 mmHg and/or a pulmonary arterial pressure (PAP) = or > 60 mmHg, and group B if MG and/or PAP were respectively lower than 15 and 60 mmHg. Endpoints considered were death, hospitalization for acute pulmonary edema, complications associated with mitral valve disease and mitral valve interventions (percutaneous or surgical). Mean follow-up was 73.6+/-16.6 months. RESULTS:Mean age was 55.2+/-10.5 years; 83.7% were women; NYHA class was I-II-III respectively in 18.6%, 58.1% and 23.3% of the patients; mean mitral valve area was 1.39+/-0.26 cm2; mean MG 8.05+/-2.54 mmHg; PAP 39.3+/-7.9 mmHg. Twenty-five patients met criteria for group A and 18 for group B. The event-free interval (27.9+/-32.1 months in group A vs 53.5+/-25.8 months in group B; P=0.008) and the 2 years event-free survival (40% for group A vs 88.9% for group B; P=0.002) showed significantly different patterns between the 2 groups. The 5 years survival analysis did not reach significance. CONCLUSION:DSE seems to detect MS patients that will have rapid evolution of their valvular disease within 24 months.
journal_name
Minerva Cardioangioljournal_title
Minerva cardioangiologicaauthors
Chirio C,Anselmino M,Mangiardi L,Morello M,Oliaro E,Omedè P,Trevi GPsubject
Has Abstractpub_date
2007-06-01 00:00:00pages
317-23issue
3eissn
0026-4725issn
1827-1618journal_volume
55pub_type
杂志文章abstract：:Hypertrophic cardiomyopathy is a diverse condition, encompassing a wide spectrum of clinical manifestations. Left ventricular outflow obstruction occurs in a proportion of patients, and is amenable to a variety of management strategies. Echocardiography plays a crucial role in the diagnosis of hypertrophic cardiomyopa...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
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abstract：BACKGROUND:Aim of the present comparative clinical study was to demonstrate the efficacy of the topical application of mesoglycan, a profibrinolytic agent, for healing of leg ulcers in patients with chronic venous insufficiency. METHODS:Forty patients, observed in our outpatients department, with venous leg ulcers hav...
journal_title：Minerva cardioangiologica
pub_type： 临床试验,杂志文章
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更新日期：1999-09-01 00:00:00
abstract：INTRODUCTION:The impact of the 'International Criteria' for ECG interpretation in athletes has further improved the diagnostic accuracy of the 12-lead ECG use for pre-participation screening (PPS) and these criteria have been evaluated in different populations of athletes and settings proving good results. EVIDENCE AC...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：10.23736/S0026-4725.20.05347-5
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journal_title：Minerva cardioangiologica
pub_type： 杂志文章
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journal_title：Minerva cardioangiologica
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journal_title：Minerva cardioangiologica
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Minerva cardioangiologica
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